Hmgn3 (high mobility group nucleosomal binding domain 3) - Rat Genome Database

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Gene: Hmgn3 (high mobility group nucleosomal binding domain 3) Rattus norvegicus
Analyze
Symbol: Hmgn3
Name: high mobility group nucleosomal binding domain 3
RGD ID: 1359106
Description: Predicted to enable chromatin binding activity. Predicted to be involved in chromatin organization. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II and regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of chromatin. Predicted to be active in nucleus. Orthologous to human HMGN3 (high mobility group nucleosomal binding domain 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: high mobility group nucleosome binding domain 3; high mobility group nucleosome-binding domain-containing protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8892,902,555 - 92,939,980 (-)NCBIGRCr8
mRatBN7.2884,022,493 - 84,059,329 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl884,022,495 - 84,062,976 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx889,627,080 - 89,663,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0887,856,064 - 87,892,724 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0885,719,317 - 85,755,998 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0890,628,203 - 90,665,055 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl890,628,209 - 90,664,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0890,151,447 - 90,188,104 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4888,168,415 - 88,205,046 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1888,187,870 - 88,224,501 (-)NCBI
Celera883,680,164 - 83,716,759 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dimethylselenide  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
finasteride  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
glafenine  (EXP)
indole-3-methanol  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
methylparaben  (ISO)
N,N-diethyl-m-toluamide  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
permethrin  (EXP)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
trovafloxacin  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
vincaleukoblastine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
cytosol  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11356838   PMID:15082770   PMID:15489334   PMID:19651901   PMID:19885867   PMID:21278158   PMID:25002582   PMID:31904090  


Genomics

Comparative Map Data
Hmgn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8892,902,555 - 92,939,980 (-)NCBIGRCr8
mRatBN7.2884,022,493 - 84,059,329 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl884,022,495 - 84,062,976 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx889,627,080 - 89,663,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0887,856,064 - 87,892,724 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0885,719,317 - 85,755,998 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0890,628,203 - 90,665,055 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl890,628,209 - 90,664,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0890,151,447 - 90,188,104 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4888,168,415 - 88,205,046 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1888,187,870 - 88,224,501 (-)NCBI
Celera883,680,164 - 83,716,759 (-)NCBICelera
Cytogenetic Map8q31NCBI
HMGN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38679,201,245 - 79,234,682 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl679,201,245 - 79,234,689 (-)EnsemblGRCh38hg38GRCh38
GRCh37679,910,962 - 79,944,399 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36679,967,681 - 80,001,174 (-)NCBINCBI36Build 36hg18NCBI36
Build 34679,967,682 - 80,001,174NCBI
Celera680,298,225 - 80,331,717 (-)NCBICelera
Cytogenetic Map6q14.1NCBI
HuRef677,104,244 - 77,137,758 (-)NCBIHuRef
CHM1_1680,008,452 - 80,041,944 (-)NCBICHM1_1
T2T-CHM13v2.0680,378,935 - 80,412,370 (-)NCBIT2T-CHM13v2.0
Hmgn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39982,991,995 - 83,029,411 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl982,992,001 - 83,028,738 (-)EnsemblGRCm39 Ensembl
GRCm38983,109,942 - 83,147,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl983,109,948 - 83,146,685 (-)EnsemblGRCm38mm10GRCm38
MGSCv37983,003,549 - 83,040,214 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36982,906,666 - 82,943,322 (-)NCBIMGSCv36mm8
Celera980,206,588 - 80,244,118 (-)NCBICelera
Cytogenetic Map9E2NCBI
cM Map945.29NCBI
Hmgn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555027,037,126 - 7,064,053 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555027,037,126 - 7,064,333 (-)NCBIChiLan1.0ChiLan1.0
HMGN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2599,256,603 - 99,297,719 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1697,137,417 - 97,176,917 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0677,052,498 - 77,085,956 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1680,323,904 - 80,357,995 (-)NCBIpanpan1.1PanPan1.1panPan2
HMGN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11240,135,984 - 40,168,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1240,135,988 - 40,168,266 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1240,009,265 - 40,041,560 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01240,908,094 - 40,940,158 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1240,908,092 - 40,940,143 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11240,230,419 - 40,262,429 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01240,207,603 - 40,240,384 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01240,338,436 - 40,370,503 (-)NCBIUU_Cfam_GSD_1.0
Hmgn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494675,516,541 - 75,547,845 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651010,923,009 - 10,954,354 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651010,923,014 - 10,954,354 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMGN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,954,465 - 86,987,460 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,954,468 - 86,987,465 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2197,725,921 - 97,758,953 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HMGN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1133,909,460 - 3,943,339 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl133,909,430 - 3,942,394 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040180,133,659 - 180,165,973 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hmgn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248195,830,311 - 5,860,141 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248195,831,031 - 5,860,249 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hmgn3
247 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1011
Count of miRNA genes:292
Interacting mature miRNAs:374
Transcripts:ENSRNOT00000039917, ENSRNOT00000072225, ENSRNOT00000074896
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)87531177784531599Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 42 34 18 19 18 8 11 74 34 40 11 8
Low 1 1 23 23 23 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001007020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001201353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001201354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001201355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC082036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB751211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB774488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM058030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000039917   ⟹   ENSRNOP00000043980
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl890,628,209 - 90,664,554 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000072225   ⟹   ENSRNOP00000064650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl884,022,495 - 84,062,976 (-)Ensembl
Rnor_6.0 Ensembl890,628,209 - 90,664,554 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000074896   ⟹   ENSRNOP00000066015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl884,022,499 - 84,062,976 (-)Ensembl
Rnor_6.0 Ensembl890,628,209 - 90,664,554 (-)Ensembl
RefSeq Acc Id: NM_001007020   ⟹   NP_001007021
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,164 (-)NCBI
mRatBN7.2884,022,493 - 84,059,110 (-)NCBI
Rnor_6.0890,628,203 - 90,664,554 (-)NCBI
Rnor_5.0890,151,447 - 90,188,104 (-)NCBI
RGSC_v3.4888,168,415 - 88,205,046 (-)RGD
Celera883,680,164 - 83,716,759 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001201353   ⟹   NP_001188282
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,164 (-)NCBI
mRatBN7.2884,022,493 - 84,059,110 (-)NCBI
Rnor_6.0890,628,203 - 90,664,554 (-)NCBI
Rnor_5.0890,151,447 - 90,188,104 (-)NCBI
Celera883,680,164 - 83,716,759 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001201354   ⟹   NP_001188283
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,164 (-)NCBI
mRatBN7.2884,022,493 - 84,059,110 (-)NCBI
Rnor_6.0890,628,203 - 90,664,554 (-)NCBI
Rnor_5.0890,151,447 - 90,188,104 (-)NCBI
Celera883,680,164 - 83,716,759 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001201355   ⟹   NP_001188284
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,164 (-)NCBI
mRatBN7.2884,022,493 - 84,059,110 (-)NCBI
Rnor_6.0890,628,203 - 90,664,554 (-)NCBI
Rnor_5.0890,151,447 - 90,188,104 (-)NCBI
Celera883,680,164 - 83,716,759 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243445   ⟹   XP_006243507
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,319 (-)NCBI
mRatBN7.2884,022,975 - 84,059,258 (-)NCBI
Rnor_6.0890,628,585 - 90,665,044 (-)NCBI
Rnor_5.0890,151,447 - 90,188,104 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595402   ⟹   XP_017450891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,316 (-)NCBI
mRatBN7.2884,022,493 - 84,059,259 (-)NCBI
Rnor_6.0890,628,203 - 90,664,974 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595404   ⟹   XP_017450893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,987 - 92,939,980 (-)NCBI
mRatBN7.2884,022,827 - 84,059,322 (-)NCBI
Rnor_6.0890,628,586 - 90,665,055 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595405   ⟹   XP_017450894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,350 (-)NCBI
mRatBN7.2884,022,493 - 84,059,311 (-)NCBI
Rnor_6.0890,628,203 - 90,665,050 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039080656   ⟹   XP_038936584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,987 - 92,939,980 (-)NCBI
mRatBN7.2884,022,828 - 84,059,327 (-)NCBI
RefSeq Acc Id: XM_039080658   ⟹   XP_038936586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,319 (-)NCBI
mRatBN7.2884,022,493 - 84,059,259 (-)NCBI
RefSeq Acc Id: XM_039080659   ⟹   XP_038936587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,907,637 (-)NCBI
mRatBN7.2884,022,493 - 84,027,503 (-)NCBI
RefSeq Acc Id: XM_063264731   ⟹   XP_063120801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8892,902,555 - 92,939,980 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001007021   ⟸   NM_001007020
- Peptide Label: isoform 2
- UniProtKB: Q66H40 (UniProtKB/Swiss-Prot),   A6I1R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001188283   ⟸   NM_001201354
- Peptide Label: isoform 3
- UniProtKB: A6I1Q9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001188282   ⟸   NM_001201353
- Peptide Label: isoform 1
- UniProtKB: A6I1Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001188284   ⟸   NM_001201355
- Peptide Label: isoform 4
- UniProtKB: Q66H40 (UniProtKB/Swiss-Prot),   M0R953 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243507   ⟸   XM_006243445
- Peptide Label: isoform X2
- UniProtKB: M0R953 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450894   ⟸   XM_017595405
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017450891   ⟸   XM_017595402
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017450893   ⟸   XM_017595404
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000043980   ⟸   ENSRNOT00000039917
RefSeq Acc Id: ENSRNOP00000066015   ⟸   ENSRNOT00000074896
RefSeq Acc Id: ENSRNOP00000064650   ⟸   ENSRNOT00000072225
RefSeq Acc Id: XP_038936586   ⟸   XM_039080658
- Peptide Label: isoform X4
- UniProtKB: M0R953 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936587   ⟸   XM_039080659
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038936584   ⟸   XM_039080656
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120801   ⟸   XM_063264731
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H40-F1-model_v2 AlphaFold Q66H40 1-95 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696152
Promoter ID:EPDNEW_R6676
Type:initiation region
Name:Hmgn3_1
Description:high mobility group nucleosomal binding domain 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0890,664,512 - 90,664,572EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359106 AgrOrtholog
BioCyc Gene G2FUF-29700 BioCyc
Ensembl Genes ENSRNOG00000031032 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072225.2 UniProtKB/TrEMBL
  ENSRNOT00000074896.4 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7130894 IMAGE-MGC_LOAD
InterPro HMGN_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:113990 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:95173 IMAGE-MGC_LOAD
NCBI Gene 113990 ENTREZGENE
PANTHER NONHISTONE CHROMOSOMAL PROTEIN HMG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23087:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HMG14_17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hmgn3 PhenoGen
PRINTS NONHISHMG17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HMG14_17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031032 RatGTEx
SMART HMG17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6I1Q7_RAT UniProtKB/TrEMBL
  A6I1Q8 ENTREZGENE, UniProtKB/TrEMBL
  A6I1Q9 ENTREZGENE, UniProtKB/TrEMBL
  A6I1R0 ENTREZGENE, UniProtKB/TrEMBL
  HMGN3_RAT UniProtKB/Swiss-Prot
  M0R5I3_RAT UniProtKB/TrEMBL
  M0R953 ENTREZGENE, UniProtKB/TrEMBL
  Q66H40 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-01 Hmgn3  high mobility group nucleosomal binding domain 3  Hmgn3  high mobility group nucleosome binding domain 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-12 Hmgn3  high mobility group nucleosome binding domain 3  Hmgn3  high mobility group nucleosomal binding domain 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Hmgn3  high mobility group nucleosomal binding domain 3      Symbol and Name status set to provisional 70820 PROVISIONAL