Gene: LRRK2 (leucine-rich repeat kinase 2)  Homo sapiens
Symbol: LRRK2
Name: leucine-rich repeat kinase 2
Description: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: augmented in rheumatoid arthritis 17; AURA17; DARDARIN; leucine-rich repeat serine/threonine-protein kinase 2; OTTHUMP00000179167; PARK8; RIPK7; ROCO2
Orthologs: Mus musculus : Lrrk2 (leucine-rich repeat kinase 2)  MGI
Rattus norvegicus : Lrrk2 (leucine-rich repeat kinase 2)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11240,463,038 - 40,607,270+NCBI
Human Genome Assembly HuRef1237,646,624 - 37,790,676+NCBI
Human Genome Assembly GRCh371240,618,813 - 40,763,087+NCBI
Human Genome Assembly Build 361238,905,081 - 39,049,354+NCBI
Human Cytogenetic Map12q12 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

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