STAU2 (staufen double-stranded RNA binding protein 2) - Rat Genome Database

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Gene: STAU2 (staufen double-stranded RNA binding protein 2) Homo sapiens
Analyze
Symbol: STAU2
Name: staufen double-stranded RNA binding protein 2
RGD ID: 1351558
HGNC Page HGNC:11371
Description: Enables double-stranded RNA binding activity. Predicted to be involved in several processes, including anterograde dendritic transport of messenger ribonucleoprotein complex; intracellular mRNA localization; and protein localization to synapse. Located in membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 39K2; 39K3; DKFZp781K0371; double-stranded RNA-binding protein Staufen homolog 2; MGC119606; staufen homolog 2; staufen, RNA binding protein, homolog 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: STAU2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38873,420,369 - 73,747,480 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl873,420,369 - 73,747,708 (-)EnsemblGRCh38hg38GRCh38
GRCh37874,332,604 - 74,659,715 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36874,624,394 - 74,821,611 (-)NCBINCBI36Build 36hg18NCBI36
Build 34874,624,397 - 74,821,611NCBI
Celera870,330,172 - 70,657,629 (-)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef869,823,519 - 70,150,737 (-)NCBIHuRef
CHM1_1874,385,185 - 74,712,036 (-)NCBICHM1_1
T2T-CHM13v2.0873,850,269 - 74,176,939 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (EXP)
aflatoxin B1  (EXP,ISO)
alpha-pinene  (EXP)
antirheumatic drug  (EXP)
aristolochic acid A  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
choline  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (EXP)
dexamethasone  (EXP)
dibutyl phthalate  (ISO)
disodium selenite  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
FR900359  (EXP)
fulvestrant  (EXP)
gallic acid  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
indometacin  (EXP)
L-methionine  (ISO)
lead(0)  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (EXP)
N-nitrosodimethylamine  (ISO)
ozone  (EXP)
PCB138  (ISO)
phenylmercury acetate  (EXP)
pirinixic acid  (ISO)
potassium chromate  (EXP)
quercetin  (EXP)
resveratrol  (EXP)
SB 431542  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
tetraphene  (ISO)
thapsigargin  (EXP)
thioacetamide  (ISO)
trichostatin A  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valproic acid  (EXP)
vanadyl sulfate  (EXP)
venlafaxine hydrochloride  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The double-stranded RNA-binding protein Staufen 2 regulates eye size. Cockburn DM, etal., Mol Cell Neurosci. 2012 Nov;51(3-4):101-11. doi: 10.1016/j.mcn.2012.08.008. Epub 2012 Aug 24.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10585778   PMID:10707969   PMID:12140260   PMID:12477932   PMID:14702039   PMID:15024055   PMID:15489334   PMID:16169070   PMID:16964243   PMID:18094122   PMID:19322201  
PMID:19454010   PMID:19946888   PMID:21081503   PMID:21145461   PMID:21266579   PMID:21508097   PMID:21873635   PMID:21903422   PMID:22658674   PMID:22681889   PMID:23125361   PMID:23263869  
PMID:24144296   PMID:24457600   PMID:24520823   PMID:24778252   PMID:25665578   PMID:26186194   PMID:26496610   PMID:26777405   PMID:26843428   PMID:26949251   PMID:28302793   PMID:28514442  
PMID:29395067   PMID:29509190   PMID:29845934   PMID:29955894   PMID:30209976   PMID:30463901   PMID:30471916   PMID:30561431   PMID:30629181   PMID:30833792   PMID:31048545   PMID:31332168  
PMID:31343991   PMID:31527615   PMID:31586073   PMID:31594818   PMID:31640799   PMID:32149426   PMID:32513696   PMID:32687490   PMID:32707033   PMID:32807901   PMID:32877691   PMID:32994395  
PMID:33087562   PMID:33301849   PMID:33306668   PMID:33441653   PMID:33663378   PMID:33916271   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34159380   PMID:34597346   PMID:34732716  
PMID:34767673   PMID:34795231   PMID:34960728   PMID:35012549   PMID:35013218   PMID:35140242   PMID:35211260   PMID:35241646   PMID:35271311   PMID:35337019   PMID:35338135   PMID:35439318  
PMID:35446349   PMID:35509820   PMID:35652658   PMID:35777956   PMID:35819319   PMID:35944360   PMID:36215168   PMID:36232890   PMID:36244648   PMID:36252997   PMID:36373674   PMID:36526897  
PMID:36643863   PMID:36779422   PMID:37439148   PMID:37689310   PMID:37827155  


Genomics

Comparative Map Data
STAU2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38873,420,369 - 73,747,480 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl873,420,369 - 73,747,708 (-)EnsemblGRCh38hg38GRCh38
GRCh37874,332,604 - 74,659,715 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36874,624,394 - 74,821,611 (-)NCBINCBI36Build 36hg18NCBI36
Build 34874,624,397 - 74,821,611NCBI
Celera870,330,172 - 70,657,629 (-)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef869,823,519 - 70,150,737 (-)NCBIHuRef
CHM1_1874,385,185 - 74,712,036 (-)NCBICHM1_1
T2T-CHM13v2.0873,850,269 - 74,176,939 (-)NCBIT2T-CHM13v2.0
Stau2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,299,027 - 16,591,228 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,298,898 - 16,590,336 (-)EnsemblGRCm39 Ensembl
GRCm38116,228,803 - 16,520,332 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,228,674 - 16,520,112 (-)EnsemblGRCm38mm10GRCm38
MGSCv37116,218,891 - 16,509,383 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36116,329,412 - 16,360,609 (-)NCBIMGSCv36mm8
Celera116,163,216 - 16,444,255 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map15.05NCBI
Stau2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr857,623,528 - 7,868,206 (+)NCBIGRCr8
mRatBN7.252,840,741 - 3,084,935 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl52,840,765 - 3,084,929 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx54,956,947 - 5,202,341 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.056,595,823 - 6,841,200 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.056,301,201 - 6,537,576 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.052,257,910 - 2,497,429 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.052,255,014 - 2,485,906 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.452,084,331 - 2,182,359 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.152,084,330 - 2,086,001 (+)NCBI
Celera52,454,153 - 2,687,606 (+)NCBICelera
Cytogenetic Map5q11NCBI
Stau2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554446,538,310 - 6,778,708 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554446,538,310 - 6,777,132 (+)NCBIChiLan1.0ChiLan1.0
STAU2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2789,167,182 - 89,492,005 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1864,796,944 - 65,121,802 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0869,958,735 - 70,283,591 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1871,605,582 - 71,929,331 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl871,606,583 - 71,929,167 (-)Ensemblpanpan1.1panPan2
STAU2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,995,229 - 22,292,107 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,996,108 - 22,283,355 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2922,259,472 - 22,555,897 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02922,105,311 - 22,402,291 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2922,104,509 - 22,402,788 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12922,163,044 - 22,459,454 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02922,199,867 - 22,496,340 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02922,481,150 - 22,777,972 (-)NCBIUU_Cfam_GSD_1.0
Stau2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530356,978,148 - 57,276,321 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366482,171,957 - 2,469,869 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366482,172,263 - 2,470,494 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAU2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl462,139,464 - 62,455,499 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1462,139,456 - 62,455,509 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2467,846,349 - 68,043,836 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STAU2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1869,025,827 - 69,360,760 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl869,025,436 - 69,322,539 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603972,011,270 - 72,345,819 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stau2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474417,434,686 - 17,727,127 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474417,434,733 - 17,726,348 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STAU2
29 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8q21.11-21.13(chr8:73519300-82655582)x1 copy number loss See cases [RCV000051117] Chr8:73519300..82655582 [GRCh38]
Chr8:74431535..83567817 [GRCh37]
Chr8:74594089..83730372 [NCBI36]
Chr8:8q21.11-21.13		 pathogenic
GRCh38/hg38 8q12.1-21.13(chr8:57361243-79170078)x3 copy number gain See cases [RCV000053653] Chr8:57361243..79170078 [GRCh38]
Chr8:58273802..80082313 [GRCh37]
Chr8:58436356..80244868 [NCBI36]
Chr8:8q12.1-21.13		 pathogenic
GRCh38/hg38 8q12.3-21.13(chr8:61691800-82537696)x3 copy number gain See cases [RCV000053654] Chr8:61691800..82537696 [GRCh38]
Chr8:62604359..83449931 [GRCh37]
Chr8:62766913..83612486 [NCBI36]
Chr8:8q12.3-21.13		 pathogenic
GRCh38/hg38 8q13.3-21.11(chr8:70948393-74353284)x3 copy number gain See cases [RCV000053655] Chr8:70948393..74353284 [GRCh38]
Chr8:71860628..75265519 [GRCh37]
Chr8:72023182..75428074 [NCBI36]
Chr8:8q13.3-21.11		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
NM_001164380.1(STAU2):c.1223-6803A>G single nucleotide variant Lung cancer [RCV000107665] Chr8:73559122 [GRCh38]
Chr8:74471357 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.1(STAU2):c.411-865G>T single nucleotide variant Lung cancer [RCV000107666] Chr8:73618316 [GRCh38]
Chr8:74530551 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.1(STAU2):c.410+12674G>T single nucleotide variant Lung cancer [RCV000107667] Chr8:73660433 [GRCh38]
Chr8:74572668 [GRCh37]
Chr8:8q21.11		 uncertain significance
GRCh38/hg38 8q13.1-22.1(chr8:66171669-93505509)x3 copy number gain See cases [RCV000137050] Chr8:66171669..93505509 [GRCh38]
Chr8:67083904..94517737 [GRCh37]
Chr8:67246458..94586913 [NCBI36]
Chr8:8q13.1-22.1		 pathogenic
GRCh38/hg38 8q13.1-21.13(chr8:66633845-80100089)x3 copy number gain See cases [RCV000138027] Chr8:66633845..80100089 [GRCh38]
Chr8:67546080..81012324 [GRCh37]
Chr8:67708634..81174879 [NCBI36]
Chr8:8q13.1-21.13		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh37/hg19 8q13.3-21.13(chr8:70971013-82019151)x3 copy number gain See cases [RCV000240367] Chr8:70971013..82019151 [GRCh37]
Chr8:8q13.3-21.13		 likely pathogenic
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3		 pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3		 pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
NM_001164380.2(STAU2):c.789C>T (p.Arg263=) single nucleotide variant not provided [RCV000950168] Chr8:73613846 [GRCh38]
Chr8:74526081 [GRCh37]
Chr8:8q21.11		 benign
NM_001164380.2(STAU2):c.931C>T (p.Arg311Cys) single nucleotide variant Inborn genetic diseases [RCV003248551] Chr8:73603824 [GRCh38]
Chr8:74516059 [GRCh37]
Chr8:8q21.11		 uncertain significance
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
NM_001164380.2(STAU2):c.1040G>T (p.Gly347Val) single nucleotide variant not provided [RCV000916882] Chr8:73595287 [GRCh38]
Chr8:74507522 [GRCh37]
Chr8:8q21.11		 benign
NM_001164380.2(STAU2):c.1390A>G (p.Ile464Val) single nucleotide variant Inborn genetic diseases [RCV003276130] Chr8:73552152 [GRCh38]
Chr8:74464387 [GRCh37]
Chr8:8q21.11		 uncertain significance
GRCh37/hg19 8q21.11(chr8:74275902-74626066)x3 copy number gain not provided [RCV001258415] Chr8:74275902..74626066 [GRCh37]
Chr8:8q21.11		 uncertain significance
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771) copy number gain Polydactyly [RCV002280629] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
NM_001164380.2(STAU2):c.226C>T (p.Pro76Ser) single nucleotide variant not provided [RCV002251788] Chr8:73688702 [GRCh38]
Chr8:74600937 [GRCh37]
Chr8:8q21.11		 uncertain significance
GRCh37/hg19 8q13.2-24.3(chr8:70382990-146295771) copy number gain not specified [RCV002053772] Chr8:70382990..146295771 [GRCh37]
Chr8:8q13.2-24.3		 pathogenic
GRCh37/hg19 8q13.2-24.3(chr8:68912432-146295771)x2 copy number gain See cases [RCV002292707] Chr8:68912432..146295771 [GRCh37]
Chr8:8q13.2-24.3		 pathogenic
NM_001164380.2(STAU2):c.1424C>A (p.Ser475Tyr) single nucleotide variant Inborn genetic diseases [RCV003285801] Chr8:73552118 [GRCh38]
Chr8:74464353 [GRCh37]
Chr8:8q21.11		 uncertain significance
GRCh37/hg19 8q21.11(chr8:74515647-75122801)x4 copy number gain not provided [RCV002474943] Chr8:74515647..75122801 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.220A>G (p.Thr74Ala) single nucleotide variant Inborn genetic diseases [RCV002991135] Chr8:73688708 [GRCh38]
Chr8:74600943 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1505A>G (p.Tyr502Cys) single nucleotide variant Inborn genetic diseases [RCV002902233] Chr8:73552037 [GRCh38]
Chr8:74464272 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1387A>G (p.Thr463Ala) single nucleotide variant Inborn genetic diseases [RCV002683075] Chr8:73552155 [GRCh38]
Chr8:74464390 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1325A>G (p.Lys442Arg) single nucleotide variant Inborn genetic diseases [RCV002868119] Chr8:73552217 [GRCh38]
Chr8:74464452 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1393G>A (p.Ala465Thr) single nucleotide variant Inborn genetic diseases [RCV002893378] Chr8:73552149 [GRCh38]
Chr8:74464384 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1093G>T (p.Ala365Ser) single nucleotide variant Inborn genetic diseases [RCV002698273] Chr8:73595234 [GRCh38]
Chr8:74507469 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1675A>G (p.Ile559Val) single nucleotide variant Inborn genetic diseases [RCV002955396] Chr8:73421410 [GRCh38]
Chr8:74333645 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1280G>A (p.Arg427His) single nucleotide variant Inborn genetic diseases [RCV002940481] Chr8:73552262 [GRCh38]
Chr8:74464497 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1078A>G (p.Ile360Val) single nucleotide variant Inborn genetic diseases [RCV002941548] Chr8:73595249 [GRCh38]
Chr8:74507484 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.869A>G (p.Lys290Arg) single nucleotide variant Inborn genetic diseases [RCV003202094] Chr8:73613766 [GRCh38]
Chr8:74526001 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1102G>A (p.Ala368Thr) single nucleotide variant Inborn genetic diseases [RCV003195641] Chr8:73595225 [GRCh38]
Chr8:74507460 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1607G>T (p.Gly536Val) single nucleotide variant Inborn genetic diseases [RCV003349076] Chr8:73422626 [GRCh38]
Chr8:74334861 [GRCh37]
Chr8:8q21.11		 uncertain significance
NM_001164380.2(STAU2):c.1678G>A (p.Ala560Thr) single nucleotide variant Inborn genetic diseases [RCV003367615] Chr8:73421407 [GRCh38]
Chr8:74333642 [GRCh37]
Chr8:8q21.11		 uncertain significance
GRCh37/hg19 8p21.2-q21.3(chr8:27024288-89410121)x3 copy number gain not specified [RCV003986754] Chr8:27024288..89410121 [GRCh37]
Chr8:8p21.2-q21.3		 pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not specified [RCV003986742] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6885
Count of miRNA genes:1279
Interacting mature miRNAs:1621
Transcripts:ENST00000355780, ENST00000517542, ENST00000518502, ENST00000518767, ENST00000518981, ENST00000519818, ENST00000519961, ENST00000520872, ENST00000520945, ENST00000521210, ENST00000521293, ENST00000521419, ENST00000521447, ENST00000521451, ENST00000521727, ENST00000521736, ENST00000521845, ENST00000522061, ENST00000522509, ENST00000522695, ENST00000522818, ENST00000522962, ENST00000523160, ENST00000523533, ENST00000523558, ENST00000524104, ENST00000524113, ENST00000524191, ENST00000524300
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH12642  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,332,604 - 74,332,729UniSTSGRCh37
Build 36874,495,158 - 74,495,283RGDNCBI36
Celera870,330,172 - 70,330,297RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,823,519 - 69,823,644UniSTS
GeneMap99-GB4 RH Map8398.79UniSTS
NCBI RH Map8840.0UniSTS
D8S1982  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,396,376 - 74,396,551UniSTSGRCh37
Build 36874,558,930 - 74,559,105RGDNCBI36
Celera870,393,960 - 70,394,135RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,887,051 - 69,887,226UniSTS
Whitehead-YAC Contig Map8 UniSTS
SHGC-34599  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,652,391 - 74,652,540UniSTSGRCh37
Build 36874,814,945 - 74,815,094RGDNCBI36
Celera870,650,076 - 70,650,225RGD
Cytogenetic Map8q21.11UniSTS
HuRef870,143,185 - 70,143,334UniSTS
Stanford-G3 RH Map83069.0UniSTS
GeneMap99-GB4 RH Map8389.35UniSTS
Whitehead-RH Map8461.1UniSTS
NCBI RH Map8833.0UniSTS
GeneMap99-G3 RH Map83159.0UniSTS
RH93062  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,462,981 - 74,463,133UniSTSGRCh37
Build 36874,625,535 - 74,625,687RGDNCBI36
Celera870,460,649 - 70,460,801RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,953,642 - 69,953,794UniSTS
GeneMap99-GB4 RH Map8374.18UniSTS
RH94104  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,461,251 - 74,461,371UniSTSGRCh37
Build 36874,623,805 - 74,623,925RGDNCBI36
Celera870,458,919 - 70,459,039RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,951,912 - 69,952,032UniSTS
GeneMap99-GB4 RH Map8374.34UniSTS
SHGC-78998  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,513,856 - 74,514,138UniSTSGRCh37
Build 36874,676,410 - 74,676,692RGDNCBI36
Celera870,511,525 - 70,511,807RGD
Cytogenetic Map8q21.11UniSTS
HuRef870,004,512 - 70,004,794UniSTS
SHGC-85153  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,581,566 - 74,581,851UniSTSGRCh37
Build 36874,744,120 - 74,744,405RGDNCBI36
Celera870,579,236 - 70,579,521RGD
Cytogenetic Map8q21.11UniSTS
HuRef870,072,268 - 70,072,553UniSTS
TNG Radiation Hybrid Map837541.0UniSTS
RH122246  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,408,287 - 74,408,586UniSTSGRCh37
Build 36874,570,841 - 74,571,140RGDNCBI36
Celera870,405,871 - 70,406,170RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,898,944 - 69,899,243UniSTS
G63477  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,502,805 - 74,503,105UniSTSGRCh37
Build 36874,665,359 - 74,665,659RGDNCBI36
Celera870,500,480 - 70,500,780RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,993,466 - 69,993,766UniSTS
TNG Radiation Hybrid Map837521.0UniSTS
WI-17983  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,410,709 - 74,410,858UniSTSGRCh37
Build 36874,573,263 - 74,573,412RGDNCBI36
Celera870,408,293 - 70,408,442RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,901,367 - 69,901,516UniSTS
GeneMap99-GB4 RH Map8383.71UniSTS
Whitehead-RH Map8464.3UniSTS
NCBI RH Map8844.5UniSTS
WI-14265  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,461,875 - 74,462,002UniSTSGRCh37
Build 36874,624,429 - 74,624,556RGDNCBI36
Celera870,459,543 - 70,459,670RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,952,536 - 69,952,663UniSTS
GeneMap99-GB4 RH Map8374.18UniSTS
Whitehead-RH Map8460.0UniSTS
STS-AA027159  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,439,209 - 74,439,478UniSTSGRCh37
Build 36874,601,763 - 74,602,032RGDNCBI36
Celera870,436,631 - 70,436,900RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,929,871 - 69,930,140UniSTS
GeneMap99-GB4 RH Map8374.18UniSTS
A008X48  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,463,379 - 74,463,551UniSTSGRCh37
Build 36874,625,933 - 74,626,105RGDNCBI36
Celera870,461,047 - 70,461,219RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,954,040 - 69,954,212UniSTS
GeneMap99-GB4 RH MapX92.32UniSTS
SHGC-56844  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,462,629 - 74,462,718UniSTSGRCh37
Build 36874,625,183 - 74,625,272RGDNCBI36
Celera870,460,297 - 70,460,386RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,953,290 - 69,953,379UniSTS
TNG Radiation Hybrid Map837499.0UniSTS
D8S1387E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,332,700 - 74,332,817UniSTSGRCh37
Build 36874,495,254 - 74,495,371RGDNCBI36
Celera870,330,268 - 70,330,385RGD
Cytogenetic Map8q21.11UniSTS
HuRef869,823,615 - 69,823,732UniSTS
GeneMap99-GB4 RH Map8374.87UniSTS
RH44506  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,638,352 - 74,638,472UniSTSGRCh37
Build 36874,800,906 - 74,801,026RGDNCBI36
Celera870,636,036 - 70,636,156RGD
Cytogenetic Map8q21.11UniSTS
HuRef870,129,145 - 70,129,265UniSTS
GeneMap99-GB4 RH Map8396.65UniSTS
NCBI RH Map8841.8UniSTS
WI-16800  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X89,295,098 - 89,295,203UniSTSGRCh37
GRCh37874,527,936 - 74,529,550UniSTSGRCh37
Build 36X89,181,754 - 89,181,859RGDNCBI36
Celera870,525,598 - 70,527,212UniSTS
CeleraX89,772,985 - 89,773,090RGD
Cytogenetic Map8q21.11UniSTS
Cytogenetic MapXq21.31UniSTS
HuRef870,018,605 - 70,020,219UniSTS
GeneMap99-GB4 RH MapX266.52UniSTS
Whitehead-RH MapX234.9UniSTS
NCBI RH MapX531.7UniSTS
AFMB336XG5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37874,506,061 - 74,506,181UniSTSGRCh37
Build 36874,668,615 - 74,668,735RGDNCBI36
Celera870,503,735 - 70,503,851RGD
Cytogenetic Map8q21.11UniSTS
HuRef932,734,431 - 32,734,495UniSTS
HuRef869,996,722 - 69,996,838UniSTS
Whitehead-YAC Contig Map8 UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 404 705 327 112 699 83 1426 999 1619 229 425 636 43 1 208 1030 3 2
Low 2035 2264 1399 512 1234 382 2931 1194 2115 189 1035 977 131 996 1758 3
Below cutoff 22 18 4 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_014393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB210014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC018620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC027018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC100784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF459097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF459098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK307841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL079285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL079286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL079288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC071766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA311807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR627442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB501161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF458781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y19062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000355780   ⟹   ENSP00000348026
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,549,604 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000517542   ⟹   ENSP00000431111
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,551,830 - 73,746,879 (-)Ensembl
RefSeq Acc Id: ENST00000518502   ⟹   ENSP00000428284
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,552,126 - 73,746,903 (-)Ensembl
RefSeq Acc Id: ENST00000518767   ⟹   ENSP00000429005
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,552,066 - 73,747,466 (-)Ensembl
RefSeq Acc Id: ENST00000518981   ⟹   ENSP00000428664
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,551,896 - 73,747,471 (-)Ensembl
RefSeq Acc Id: ENST00000519818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,688,735 - 73,746,843 (-)Ensembl
RefSeq Acc Id: ENST00000519961   ⟹   ENSP00000430907
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,549,692 - 73,738,344 (-)Ensembl
RefSeq Acc Id: ENST00000520872
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,688,651 - 73,747,473 (-)Ensembl
RefSeq Acc Id: ENST00000520945
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,673,139 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000521210   ⟹   ENSP00000429173
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,421,212 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000521293
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,613,891 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000521419   ⟹   ENSP00000428681
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,653,658 - 73,746,888 (-)Ensembl
RefSeq Acc Id: ENST00000521447   ⟹   ENSP00000428829
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,613,927 - 73,746,849 (-)Ensembl
RefSeq Acc Id: ENST00000521451   ⟹   ENSP00000428476
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,550,547 - 73,746,884 (-)Ensembl
RefSeq Acc Id: ENST00000521727   ⟹   ENSP00000429973
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,549,786 - 73,747,697 (-)Ensembl
RefSeq Acc Id: ENST00000521736   ⟹   ENSP00000428737
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,673,230 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000521845
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,673,240 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000522061
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,688,753 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000522509   ⟹   ENSP00000427977
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,551,643 - 73,747,708 (-)Ensembl
RefSeq Acc Id: ENST00000522695   ⟹   ENSP00000428456
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,420,369 - 73,738,327 (-)Ensembl
RefSeq Acc Id: ENST00000522818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,420,959 - 73,458,787 (-)Ensembl
RefSeq Acc Id: ENST00000522962
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,653,498 - 73,746,818 (-)Ensembl
RefSeq Acc Id: ENST00000523160
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,738,301 - 73,747,366 (-)Ensembl
RefSeq Acc Id: ENST00000523533   ⟹   ENSP00000430511
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,527,369 - 73,582,830 (-)Ensembl
RefSeq Acc Id: ENST00000523558   ⟹   ENSP00000428741
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,421,130 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000524104   ⟹   ENSP00000430611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,652,257 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000524113
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,672,982 - 73,746,840 (-)Ensembl
RefSeq Acc Id: ENST00000524191
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,672,184 - 73,746,882 (-)Ensembl
RefSeq Acc Id: ENST00000524300   ⟹   ENSP00000428756
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl873,420,369 - 73,746,840 (-)Ensembl
RefSeq Acc Id: NM_001164380   ⟹   NP_001157852
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,420,369 - 73,746,840 (-)NCBI
GRCh37874,332,604 - 74,659,943 (-)RGD
Celera870,330,172 - 70,657,629 (-)RGD
HuRef869,823,519 - 70,150,737 (-)RGD
CHM1_1874,385,185 - 74,711,252 (-)NCBI
T2T-CHM13v2.0873,850,269 - 74,176,299 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001164381   ⟹   NP_001157853
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,420,369 - 73,746,840 (-)NCBI
GRCh37874,332,604 - 74,659,943 (-)RGD
Celera870,330,172 - 70,657,629 (-)RGD
HuRef869,823,519 - 70,150,737 (-)RGD
CHM1_1874,385,185 - 74,711,252 (-)NCBI
T2T-CHM13v2.0873,850,269 - 74,176,299 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001164382   ⟹   NP_001157854
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,420,369 - 73,746,840 (-)NCBI
GRCh37874,332,604 - 74,659,943 (-)RGD
Celera870,330,172 - 70,657,629 (-)RGD
HuRef869,823,519 - 70,150,737 (-)RGD
CHM1_1874,385,185 - 74,711,252 (-)NCBI
T2T-CHM13v2.0873,850,269 - 74,176,299 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001164383   ⟹   NP_001157855
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,420,369 - 73,746,840 (-)NCBI
GRCh37874,332,604 - 74,659,943 (-)RGD
Celera870,330,172 - 70,657,629 (-)RGD
HuRef869,823,519 - 70,150,737 (-)RGD
CHM1_1874,385,185 - 74,711,252 (-)NCBI
T2T-CHM13v2.0873,850,269 - 74,176,299 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001164384   ⟹   NP_001157856
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,549,601 - 73,747,480 (-)NCBI
GRCh37874,332,604 - 74,659,943 (-)RGD
Celera870,330,172 - 70,657,629 (-)RGD
HuRef869,823,519 - 70,150,737 (-)RGD
CHM1_1874,514,390 - 74,712,036 (-)NCBI
T2T-CHM13v2.0873,979,510 - 74,176,939 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001164385   ⟹   NP_001157857
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,549,601 - 73,746,840 (-)NCBI
GRCh37874,332,604 - 74,659,943 (-)RGD
Celera870,330,172 - 70,657,629 (-)RGD
HuRef869,823,519 - 70,150,737 (-)RGD
CHM1_1874,514,390 - 74,711,252 (-)NCBI
T2T-CHM13v2.0873,979,510 - 74,176,299 (-)NCBI
Sequence:
RefSeq Acc Id: NM_014393   ⟹   NP_055208
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,549,601 - 73,746,840 (-)NCBI
GRCh37874,332,604 - 74,659,943 (-)RGD
Build 36874,624,394 - 74,821,611 (-)NCBI Archive
Celera870,330,172 - 70,657,629 (-)RGD
HuRef869,823,519 - 70,150,737 (-)RGD
CHM1_1874,514,390 - 74,711,252 (-)NCBI
T2T-CHM13v2.0873,979,510 - 74,176,299 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001157852 (Get FASTA)   NCBI Sequence Viewer  
  NP_001157853 (Get FASTA)   NCBI Sequence Viewer  
  NP_001157854 (Get FASTA)   NCBI Sequence Viewer  
  NP_001157855 (Get FASTA)   NCBI Sequence Viewer  
  NP_001157856 (Get FASTA)   NCBI Sequence Viewer  
  NP_001157857 (Get FASTA)   NCBI Sequence Viewer  
  NP_055208 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH08369 (Get FASTA)   NCBI Sequence Viewer  
  AAH08370 (Get FASTA)   NCBI Sequence Viewer  
  AAI10448 (Get FASTA)   NCBI Sequence Viewer  
  AAN37926 (Get FASTA)   NCBI Sequence Viewer  
  AAN37927 (Get FASTA)   NCBI Sequence Viewer  
  BAA91766 (Get FASTA)   NCBI Sequence Viewer  
  BAA92111 (Get FASTA)   NCBI Sequence Viewer  
  BAB14522 (Get FASTA)   NCBI Sequence Viewer  
  BAE06096 (Get FASTA)   NCBI Sequence Viewer  
  BAF82830 (Get FASTA)   NCBI Sequence Viewer  
  BAG37183 (Get FASTA)   NCBI Sequence Viewer  
  BAH11522 (Get FASTA)   NCBI Sequence Viewer  
  BAH11582 (Get FASTA)   NCBI Sequence Viewer  
  BAH11778 (Get FASTA)   NCBI Sequence Viewer  
  BAH13900 (Get FASTA)   NCBI Sequence Viewer  
  CAB64341 (Get FASTA)   NCBI Sequence Viewer  
  CAH10527 (Get FASTA)   NCBI Sequence Viewer  
  EAW87003 (Get FASTA)   NCBI Sequence Viewer  
  EAW87004 (Get FASTA)   NCBI Sequence Viewer  
  EAW87005 (Get FASTA)   NCBI Sequence Viewer  
  EAW87006 (Get FASTA)   NCBI Sequence Viewer  
  EAW87007 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000348026
  ENSP00000348026.5
  ENSP00000427977
  ENSP00000427977.1
  ENSP00000428284.1
  ENSP00000428456
  ENSP00000428456.1
  ENSP00000428476.1
  ENSP00000428664.1
  ENSP00000428681.1
  ENSP00000428737.1
  ENSP00000428741
  ENSP00000428741.1
  ENSP00000428756
  ENSP00000428756.1
  ENSP00000428829.1
  ENSP00000429005.1
  ENSP00000429173
  ENSP00000429173.1
  ENSP00000429973.1
  ENSP00000430511.1
  ENSP00000430611.1
  ENSP00000430907.1
  ENSP00000431111
  ENSP00000431111.1
GenBank Protein Q9NUL3 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001157852   ⟸   NM_001164380
- Peptide Label: isoform a
- UniProtKB: Q9NVI5 (UniProtKB/Swiss-Prot),   Q96HM1 (UniProtKB/Swiss-Prot),   Q96HM0 (UniProtKB/Swiss-Prot),   Q6AHY7 (UniProtKB/Swiss-Prot),   E9PF50 (UniProtKB/Swiss-Prot),   E9PF26 (UniProtKB/Swiss-Prot),   E9PEI3 (UniProtKB/Swiss-Prot),   E7ER74 (UniProtKB/Swiss-Prot),   B7Z8B4 (UniProtKB/Swiss-Prot),   B7Z292 (UniProtKB/Swiss-Prot),   B7Z1I6 (UniProtKB/Swiss-Prot),   Q9UGG6 (UniProtKB/Swiss-Prot),   Q9NUL3 (UniProtKB/Swiss-Prot),   A0A0A0MTC5 (UniProtKB/TrEMBL),   E7EVJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157853   ⟸   NM_001164381
- Peptide Label: isoform b
- UniProtKB: A8K276 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157854   ⟸   NM_001164382
- Peptide Label: isoform c
- UniProtKB: A8K276 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157855   ⟸   NM_001164383
- Peptide Label: isoform d
- UniProtKB: E5RJN7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157856   ⟸   NM_001164384
- Peptide Label: isoform e
- UniProtKB: A8K276 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_055208   ⟸   NM_014393
- Peptide Label: isoform e
- UniProtKB: A8K276 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157857   ⟸   NM_001164385
- Peptide Label: isoform f
- UniProtKB: A8K276 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000431111   ⟸   ENST00000517542
RefSeq Acc Id: ENSP00000428664   ⟸   ENST00000518981
RefSeq Acc Id: ENSP00000429005   ⟸   ENST00000518767
RefSeq Acc Id: ENSP00000428284   ⟸   ENST00000518502
RefSeq Acc Id: ENSP00000430907   ⟸   ENST00000519961
RefSeq Acc Id: ENSP00000429173   ⟸   ENST00000521210
RefSeq Acc Id: ENSP00000429973   ⟸   ENST00000521727
RefSeq Acc Id: ENSP00000428737   ⟸   ENST00000521736
RefSeq Acc Id: ENSP00000428681   ⟸   ENST00000521419
RefSeq Acc Id: ENSP00000428829   ⟸   ENST00000521447
RefSeq Acc Id: ENSP00000428476   ⟸   ENST00000521451
RefSeq Acc Id: ENSP00000428456   ⟸   ENST00000522695
RefSeq Acc Id: ENSP00000427977   ⟸   ENST00000522509
RefSeq Acc Id: ENSP00000430511   ⟸   ENST00000523533
RefSeq Acc Id: ENSP00000428741   ⟸   ENST00000523558
RefSeq Acc Id: ENSP00000428756   ⟸   ENST00000524300
RefSeq Acc Id: ENSP00000430611   ⟸   ENST00000524104
RefSeq Acc Id: ENSP00000348026   ⟸   ENST00000355780
Protein Domains
DRBM   Staufen C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NUL3-F1-model_v2 AlphaFold Q9NUL3 1-570 view protein structure

Promoters
RGD ID:7213535
Promoter ID:EPDNEW_H12513
Type:initiation region
Name:STAU2_1
Description:staufen double-stranded RNA binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12514  EPDNEW_H12515  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,746,840 - 73,746,900EPDNEW
RGD ID:7213537
Promoter ID:EPDNEW_H12514
Type:initiation region
Name:STAU2_2
Description:staufen double-stranded RNA binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12513  EPDNEW_H12515  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,746,956 - 73,747,016EPDNEW
RGD ID:7213539
Promoter ID:EPDNEW_H12515
Type:initiation region
Name:STAU2_3
Description:staufen double-stranded RNA binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12513  EPDNEW_H12514  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38873,747,471 - 73,747,531EPDNEW
RGD ID:6807050
Promoter ID:HG_KWN:61527
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Jurkat
Transcripts:UC003XZO.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36874,813,166 - 74,813,666 (-)MPROMDB
RGD ID:6807051
Promoter ID:HG_KWN:61528
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000355780,   NM_001164380,   NM_001164381,   NM_001164382,   NM_001164383,   NM_001164384,   NM_001164385,   UC003XZQ.1,   UC003XZR.2,   UC003XZS.2,   UC010LZL.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36874,821,646 - 74,822,722 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11371 AgrOrtholog
COSMIC STAU2 COSMIC
Ensembl Genes ENSG00000040341 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000355780 ENTREZGENE
  ENST00000355780.9 UniProtKB/Swiss-Prot
  ENST00000517542 ENTREZGENE
  ENST00000517542.5 UniProtKB/Swiss-Prot
  ENST00000518502.5 UniProtKB/TrEMBL
  ENST00000518767.5 UniProtKB/TrEMBL
  ENST00000518981.5 UniProtKB/TrEMBL
  ENST00000519961.5 UniProtKB/TrEMBL
  ENST00000521210 ENTREZGENE
  ENST00000521210.5 UniProtKB/Swiss-Prot
  ENST00000521419.5 UniProtKB/TrEMBL
  ENST00000521447.5 UniProtKB/TrEMBL
  ENST00000521451.5 UniProtKB/Swiss-Prot
  ENST00000521727.5 UniProtKB/TrEMBL
  ENST00000521736.5 UniProtKB/TrEMBL
  ENST00000522509 ENTREZGENE
  ENST00000522509.5 UniProtKB/Swiss-Prot
  ENST00000522695 ENTREZGENE
  ENST00000522695.5 UniProtKB/Swiss-Prot
  ENST00000523533.5 UniProtKB/TrEMBL
  ENST00000523558 ENTREZGENE
  ENST00000523558.5 UniProtKB/Swiss-Prot
  ENST00000524104.5 UniProtKB/Swiss-Prot
  ENST00000524300 ENTREZGENE
  ENST00000524300.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.160.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.1360 UniProtKB/TrEMBL
GTEx ENSG00000040341 GTEx
HGNC ID HGNC:11371 ENTREZGENE
Human Proteome Map STAU2 Human Proteome Map
InterPro dsRBD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAU2_DSRM_1 UniProtKB/TrEMBL
  STAU2_DSRM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAU2_DSRM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAU2_DSRM_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Staufen_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:27067 UniProtKB/Swiss-Prot
NCBI Gene 27067 ENTREZGENE
OMIM 605920 OMIM
PANTHER DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATERNAL EFFECT PROTEIN STAUFEN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam dsrm UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Staufen_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36189 PharmGKB
PROSITE DS_RBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DSRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MTC5 ENTREZGENE
  A8K276 ENTREZGENE, UniProtKB/TrEMBL
  B7Z1I6 ENTREZGENE
  B7Z292 ENTREZGENE
  B7Z8B4 ENTREZGENE
  E5RFK1_HUMAN UniProtKB/TrEMBL
  E5RGQ5_HUMAN UniProtKB/TrEMBL
  E5RGT3_HUMAN UniProtKB/TrEMBL
  E5RJ67_HUMAN UniProtKB/TrEMBL
  E5RJN7 ENTREZGENE, UniProtKB/TrEMBL
  E7EPX0_HUMAN UniProtKB/TrEMBL
  E7ER74 ENTREZGENE
  E7EVI1_HUMAN UniProtKB/TrEMBL
  E7EVJ4 ENTREZGENE, UniProtKB/TrEMBL
  E9PEI3 ENTREZGENE
  E9PF26 ENTREZGENE
  E9PF50 ENTREZGENE
  H0YBY0_HUMAN UniProtKB/TrEMBL
  Q2TBD5_HUMAN UniProtKB/TrEMBL
  Q4LE57_HUMAN UniProtKB/TrEMBL
  Q6AHY7 ENTREZGENE
  Q96HM0 ENTREZGENE
  Q96HM1 ENTREZGENE
  Q9NUL3 ENTREZGENE
  Q9NVI5 ENTREZGENE
  Q9UGG6 ENTREZGENE
  STAU2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A0A0A0MTC5 UniProtKB/Swiss-Prot
  B7Z1I6 UniProtKB/Swiss-Prot
  B7Z292 UniProtKB/Swiss-Prot
  B7Z8B4 UniProtKB/Swiss-Prot
  E7ER74 UniProtKB/Swiss-Prot
  E9PEI3 UniProtKB/Swiss-Prot
  E9PF26 UniProtKB/Swiss-Prot
  E9PF50 UniProtKB/Swiss-Prot
  Q6AHY7 UniProtKB/Swiss-Prot
  Q96HM0 UniProtKB/Swiss-Prot
  Q96HM1 UniProtKB/Swiss-Prot
  Q9NVI5 UniProtKB/Swiss-Prot
  Q9UGG6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-11 STAU2  staufen double-stranded RNA binding protein 2  STAU2  staufen, RNA binding protein, homolog 2 (Drosophila)  Symbol and/or name change 5135510 APPROVED