PPP1R1B (protein phosphatase 1, regulatory (inhibitor) subunit 1B)

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Keyword

Gene: PPP1R1B (protein phosphatase 1, regulatory (inhibitor) subunit 1B) Homo sapiens

Symbol:

PPP1R1B

Name:

protein phosphatase 1, regulatory (inhibitor) subunit 1B

Description:

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

DARPP-32; DARPP32; dopamine and cAMP regulated phosphoprotein; dopamine and cAMP-regulated neuronal phosphoprotein 32; dopamine- and cAMP-regulated neuronal phosphoprotein; FLJ20940; OTTHUMP00000164273; OTTHUMP00000164274; OTTHUMP00000164275; OTTHUMP00000164276; protein phosphatase 1 regulatory subunit 1B; protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32)

Orthologs:

Mus musculus : Ppp1r1b (protein phosphatase 1, regulatory (inhibitor) subunit 1B) MGI
Rattus norvegicus : Ppp1r1b (protein phosphatase 1, regulatory (inhibitor) subunit 1B)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	17	38,570,396 - 38,580,097	+	NCBI
Human Genome Assembly HuRef	17	33,576,900 - 33,586,601	+	NCBI
Human Genome Assembly GRCh37	17	37,783,177 - 37,792,878	+	NCBI
Human Genome Assembly Build 36	17	35,036,705 - 35,046,404	+	NCBI
Human Cytogenetic Map	17	q12		NCBI
Human Genome Assembly	17	35,038,278 - 35,046,405		NCBI