HTR7 (5-hydroxytryptamine receptor 7)

Gene: HTR7 (5-hydroxytryptamine receptor 7) Homo sapiens

Analyze

Symbol:

HTR7

Name:

5-hydroxytryptamine receptor 7

RGD ID:

1346949

HGNC Page

HGNC:5302

Description:

Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; chemical synaptic transmission; and presynaptic modulation of chemical synaptic transmission. Predicted to be located in plasma membrane and trans-Golgi network membrane. Predicted to be active in dendrite; postsynaptic membrane; and presynaptic membrane. Implicated in alcohol use disorder.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; serotonin 5-HT-7 receptor; serotonin receptor 7

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Htr7 (5-hydroxytryptamine (serotonin) receptor 7)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Htr7 (5-hydroxytryptamine receptor 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Htr7 (5-hydroxytryptamine receptor 7)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	HTR7 (5-hydroxytryptamine receptor 7)	NCBI	Ortholog
Canis lupus familiaris (dog):	HTR7 (5-hydroxytryptamine receptor 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Htr7 (5-hydroxytryptamine receptor 7)	NCBI	Ortholog
Sus scrofa (pig):	HTR7 (5-hydroxytryptamine receptor 7)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	HTR7 (5-hydroxytryptamine receptor 7)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Htr7 (5-hydroxytryptamine receptor 7)	NCBI	Ortholog
Other homologs ²
Rattus norvegicus (Norway rat):	Gclc (glutamate-cysteine ligase, catalytic subunit)	HGNC	OMA
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Htr7 (5-hydroxytryptamine receptor 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Htr7 (5-hydroxytryptamine (serotonin) receptor 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	htr7a (5-hydroxytryptamine (serotonin) receptor 7a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	5-HT7	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ser-7	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	htr7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	htr7.S	Alliance	DIOPT (Xenbase)
Xenopus laevis (African clawed frog):	htr7.L	Alliance	DIOPT (Xenbase)

Related Pseudogenes:

HTR7P1

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	90,740,823 - 90,858,039 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	90,740,823 - 90,858,039 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	92,500,580 - 92,617,796 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	92,490,555 - 92,607,651 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	92,490,557 - 92,607,651	NCBI
Celera	10	86,247,007 - 86,364,124 (-)	NCBI		Celera
Cytogenetic Map	10	q23.31	NCBI
HuRef	10	86,129,586 - 86,246,677 (-)	NCBI		HuRef
CHM1_1	10	92,778,457 - 92,895,518 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	91,624,488 - 91,741,713 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alcohol use disorder (IAGP)

amnestic disorder (ISO)

anxiety disorder (EXP,ISO)

Brain Injuries (ISO)

childhood absence epilepsy (ISO)

cognitive disorder (ISO)

depressive disorder (EXP,ISO)

epilepsy (ISO)

genetic disease (IAGP)

Hyperalgesia (ISO)

Hyperkinesis (ISO)

irritable bowel syndrome (ISO)

learning disability (EXP)

Memory Disorders (EXP)

migraine (ISO)

muscular disease (EXP)

obsessive-compulsive disorder (ISO)

Pain (EXP)

Peripheral Nerve Injuries (ISO)

schizophrenia (EXP)

sleep disorder (EXP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

3',5'-cyclic AMP (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-carboxamidotryptamine (EXP)

5-fluorouracil (EXP)

5-methoxytryptamine (EXP)

6-propyl-2-thiouracil (ISO)

8-OH-DPAT (EXP)

aflatoxin B1 (EXP)

all-trans-retinoic acid (EXP)

ammonium chloride (ISO)

amphetamine (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

bromocriptine (EXP)

buta-1,3-diene (ISO)

calcium atom (ISO)

calcium(0) (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

clozapine (EXP)

colforsin daropate hydrochloride (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (EXP)

Cuprizon (ISO)

cyproheptadine (EXP)

decabromodiphenyl ether (ISO)

dextran sulfate (ISO)

diazinon (ISO)

dioxygen (EXP,ISO)

flavonoids (ISO)

folic acid (ISO)

furan (ISO)

glycidol (ISO)

ketanserin (EXP)

L-methionine (ISO)

levonorgestrel (EXP)

lipopolysaccharide (EXP,ISO)

lisuride (EXP)

lurasidone hydrochloride (EXP)

mercury atom (EXP)

mercury(0) (EXP)

mesulergine (EXP)

metergoline (EXP)

methiothepin (EXP)

mianserin (EXP)

mono(2-ethylhexyl) phthalate (EXP)

N-nitrosodiethylamine (ISO)

nickel sulfate (EXP)

paliperidone palmitate (EXP)

PD 0325901 (EXP)

risperidone (EXP)

ritanserin (EXP)

rotenone (EXP)

serotonin (EXP)

silicon dioxide (EXP)

sodium arsenite (EXP)

spiperone (EXP)

tamoxifen (EXP)

testosterone undecanoate (EXP)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

tunicamycin (ISO)

vortioxetine (EXP)

zinc atom (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating serotonin receptor signaling pathway (ISO)

behavioral response to pain (ISO)

blood circulation (TAS)

chemical synaptic transmission (IBA,IEA,TAS)

circadian rhythm (IEA,TAS)

detection of mechanical stimulus involved in sensory perception of pain (ISO)

dopaminergic neuron differentiation (ISO)

G protein-coupled receptor signaling pathway (IEA)

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (IBA,IEA,TAS)

G protein-coupled serotonin receptor signaling pathway (IEA)

long-term synaptic potentiation (ISO)

memory (ISO)

negative regulation of serotonin secretion (ISO)

positive regulation of neuron projection development (ISO)

presynaptic modulation of chemical synaptic transmission (ISO)

regulation of vein smooth muscle contraction (ISO)

response to corticosterone (ISO)

response to electrical stimulus (ISO)

serotonin receptor signaling pathway (ISO)

signal transduction (IEA)

smooth muscle contraction (IEA)

urinary bladder smooth muscle contraction (ISO)

vasoconstriction (IEA)

Cellular Component

axon terminus (ISO)

dendrite (IBA,IEA,ISO)

membrane (IEA)

neuronal cell body (ISO)

plasma membrane (IEA,TAS)

postsynaptic membrane (ISO)

presynaptic membrane (ISO)

synapse (IEA)

synaptic vesicle (ISO)

trans-Golgi network membrane (TAS)

Molecular Function

G protein-coupled receptor activity (IEA)

G protein-coupled serotonin receptor activity (IBA,IEA,ISO,TAS)

neurotransmitter receptor activity (IBA,IEA,ISO)

protein binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

serotonin signaling pathway via receptors engaging G alphas protein family (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	null	null
2.	Blockade of 5-HT7 receptors reduces tactile allodynia in the rat.	Amaya-Castellanos E, etal., Pharmacol Biochem Behav. 2011 Oct;99(4):591-7. Epub 2011 Jun 15.
3.	Role of peripheral versus spinal 5-HT(7) receptors in the modulation of pain undersensitizing conditions.	Brenchat A, etal., Eur J Pain. 2012 Jan;16(1):72-81. doi: 10.1016/j.ejpain.2011.07.004.
4.	Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity.	Galici R, etal., Behav Pharmacol. 2008 Mar;19(2):153-9.
5.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
6.	Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy.	Graf M, etal., Neurosci Lett. 2004 Apr 8;359(1-2):45-8.
7.	The 5-HT7 receptor influences stereotypic behavior in a model of obsessive-compulsive disorder.	Hedlund PB and Sutcliffe JG, Neurosci Lett. 2007 Mar 13;414(3):247-51. Epub 2007 Jan 11.
8.	The role of 5-hydroxytryptamine 7 receptors in the phencyclidine-induced novel object recognition deficit in rats.	Horiguchi M, etal., J Pharmacol Exp Ther. 2011 Aug;338(2):605-14. Epub 2011 May 10.
9.	Effects of 5-HT drugs in prefrontal cortex during memory formation and the ketamine amnesia-model.	Liy-Salmeron G and Meneses A, Hippocampus. 2008;18(9):965-74.
10.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
11.	5-Hydroxytryptamine potentiates neurogenic contractions of rat isolated urinary bladder through both 5-HT(7) and 5-HT(2C) receptors.	Rekik M, etal., Eur J Pharmacol. 2011 Jan 10;650(1):403-10. Epub 2010 Oct 20.
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Selective inhibition of 5-HT7 receptor reduces CGRP release in an experimental model for migraine.	Wang X, etal., Headache. 2010 Apr;50(4):579-87. Epub 2010 Mar 5.
14.	Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression.	Wesolowska A, etal., Neuropharmacology. 2006 Sep;51(3):578-86. Epub 2006 Jul 7.
15.	Constitutive deletion of the serotonin-7 (5-HT(7)) receptor decreases electrical and chemical seizure thresholds.	Witkin JM, etal., Epilepsy Res. 2007 Jun;75(1):39-45. Epub 2007 May 7.
16.	Elucidating the role of 5-HT(1A) and 5-HT(7) receptors on 8-OH-DPAT-induced behavioral recovery after experimental traumatic brain injury.	Yelleswarapu NK, etal., Neurosci Lett. 2012 Mar 21.
17.	Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.	Zlojutro M, etal., Am J Med Genet B Neuropsychiatr Genet. 2011 Jan;156B(1):44-58. doi: 10.1002/ajmg.b.31136. Epub 2010 Nov 2.
18.	Expression and role of 5-HT7 receptor in brain and intestine in rats with irritable bowel syndrome.	Zou BC, etal., Chin Med J (Engl). 2007 Dec 5;120(23):2069-74.

Additional References at PubMed

PMID:7601444	PMID:7656980	PMID:8226867	PMID:8398139	PMID:9084407	PMID:9154233	PMID:9298538	PMID:10490701	PMID:11163544	PMID:11888546	PMID:11906971	PMID:11916537
PMID:12036966	PMID:12446729	PMID:12477932	PMID:12767050	PMID:14741325	PMID:15086532	PMID:15489334	PMID:15581469	PMID:15896881	PMID:16192982	PMID:16385451	PMID:16870886
PMID:16935469	PMID:17321075	PMID:17406648	PMID:17428232	PMID:17936759	PMID:18079067	PMID:18240029	PMID:18243350	PMID:18577758	PMID:18855532	PMID:19086053	PMID:19156168
PMID:19233240	PMID:19439818	PMID:19455600	PMID:19486527	PMID:20468064	PMID:20602615	PMID:20827463	PMID:21424680	PMID:21873635	PMID:22245496	PMID:22543085	PMID:23355731
PMID:24736177	PMID:24935787	PMID:25070732	PMID:25228519	PMID:25706089	PMID:26609891	PMID:26797415	PMID:27016479	PMID:27380831	PMID:28455702	PMID:28745550	PMID:29079700
PMID:30021884	PMID:30827505	PMID:31172579	PMID:31892309	PMID:31941109	PMID:33081564	PMID:33528589	PMID:34555475	PMID:36006564

Genomics

Comparative Map Data

HTR7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	90,740,823 - 90,858,039 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	90,740,823 - 90,858,039 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	92,500,580 - 92,617,796 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	92,490,555 - 92,607,651 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	92,490,557 - 92,607,651	NCBI
Celera	10	86,247,007 - 86,364,124 (-)	NCBI		Celera
Cytogenetic Map	10	q23.31	NCBI
HuRef	10	86,129,586 - 86,246,677 (-)	NCBI		HuRef
CHM1_1	10	92,778,457 - 92,895,518 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	91,624,488 - 91,741,713 (-)	NCBI		T2T-CHM13v2.0

Htr7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	35,935,815 - 36,035,533 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	35,936,134 - 36,034,907 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	35,958,415 - 36,058,133 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	35,958,734 - 36,057,507 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	36,033,217 - 36,131,850 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	36,025,416 - 36,122,486 (-)	NCBI		MGSCv36	mm8
Celera	19	36,736,456 - 36,835,310 (-)	NCBI		Celera
Cytogenetic Map	19	C2	NCBI
cM Map	19	30.3	NCBI

Htr7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	243,049,064 - 243,173,636 (-)	NCBI		GRCr8
mRatBN7.2	1	233,636,442 - 233,761,063 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	233,636,452 - 233,760,626 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	242,035,877 - 242,157,610 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	248,959,213 - 249,074,281 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	241,797,382 - 241,912,442 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	254,547,964 - 254,671,811 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	254,547,620 - 254,671,778 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	261,759,122 - 261,879,914 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	240,136,279 - 240,260,620 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	240,308,574 - 240,434,503 (-)	NCBI
Celera	1	230,737,463 - 230,859,847 (-)	NCBI		Celera
Cytogenetic Map	1	q53	NCBI

Htr7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	2,321,420 - 2,420,530 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	2,321,420 - 2,420,420 (+)	NCBI	ChiLan1.0	ChiLan1.0

HTR7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	102,745,099 - 102,888,149 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	102,751,872 - 102,893,463 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	87,480,970 - 87,598,212 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	91,008,278 - 91,125,416 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	91,009,941 - 91,125,158 (-)	Ensembl	panpan1.1		panPan2

HTR7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	5,438,872 - 5,524,385 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	5,440,388 - 5,524,191 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	5,605,815 - 5,691,701 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	5,658,606 - 5,744,502 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	5,660,149 - 5,744,487 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	5,415,879 - 5,501,608 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	5,454,660 - 5,540,434 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	5,588,358 - 5,595,285 (-)	NCBI		UU_Cfam_GSD_1.0

Htr7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	41,937,016 - 42,106,548 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936601	3,569,544 - 3,626,797 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936601	3,569,626 - 3,626,782 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HTR7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	102,444,588 - 102,548,907 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	102,443,312 - 102,548,894 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	111,526,055 - 111,660,097 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HTR7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	84,081,713 - 84,191,112 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	84,083,396 - 84,190,876 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	44,783,137 - 44,901,015 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Htr7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	1,960,057 - 2,067,038 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	1,960,985 - 2,067,086 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in HTR7
17 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 10q23.31(chr10:90603795-90835134)x3	copy number gain	See cases [RCV000135855]	Chr10:90603795..90835134 [GRCh38] Chr10:92363552..92594891 [GRCh37] Chr10:92353532..92584871 [NCBI36] Chr10:10q23.31	benign
GRCh38/hg38 10q23.31(chr10:90327423-90845362)x3	copy number gain	See cases [RCV000142202]	Chr10:90327423..90845362 [GRCh38] Chr10:92087180..92605119 [GRCh37] Chr10:92077160..92595099 [NCBI36] Chr10:10q23.31	likely benign\|uncertain significance
GRCh37/hg19 10q23.31(chr10:92095432-92594891)x3	copy number gain	not provided [RCV000762771]	Chr10:92095432..92594891 [GRCh37] Chr10:10q23.31	likely benign
NM_019859.4(HTR7):c.197A>G (p.Asn66Ser)	single nucleotide variant	Inborn genetic diseases [RCV003266468]	Chr10:90857475 [GRCh38] Chr10:92617232 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q23.1-23.31(chr10:86766571-92609514)x1	copy number loss	See cases [RCV000447104]	Chr10:86766571..92609514 [GRCh37] Chr10:10q23.1-23.31	pathogenic
GRCh37/hg19 10q23.1-25.1(chr10:85557432-105804295)x1	copy number loss	Poly (ADP-Ribose) polymerase inhibitor response [RCV000431909]	Chr10:85557432..105804295 [GRCh37] Chr10:10q23.1-25.1	pathogenic\|drug response
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3	copy number gain	See cases [RCV000448750]	Chr10:93297..135378918 [GRCh37] Chr10:10p15.3-q26.3	pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)	copy number gain	See cases [RCV000511389]	Chr10:100027..135427143 [GRCh37] Chr10:10p15.3-q26.3	pathogenic\|uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3	copy number gain	See cases [RCV000510861]	Chr10:100027..135427143 [GRCh37] Chr10:10p15.3-q26.3	pathogenic
NM_019859.4(HTR7):c.415A>G (p.Ser139Gly)	single nucleotide variant	Inborn genetic diseases [RCV003292879]	Chr10:90857257 [GRCh38] Chr10:92617014 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1	copy number loss	Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438]	Chr10:42347406..135534747 [GRCh37] Chr10:10q11.21-26.3	drug response
NM_019859.4(HTR7):c.236T>G (p.Val79Gly)	single nucleotide variant	Inborn genetic diseases [RCV003249887]	Chr10:90857436 [GRCh38] Chr10:92617193 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q23.31-23.32(chr10:92605118-92926773)x1	copy number loss	See cases [RCV000512278]	Chr10:92605118..92926773 [GRCh37] Chr10:10q23.31-23.32	uncertain significance
GRCh37/hg19 10q23.1-23.32(chr10:83379241-93219169)x1	copy number loss	not provided [RCV000683284]	Chr10:83379241..93219169 [GRCh37] Chr10:10q23.1-23.32	pathogenic
GRCh37/hg19 10q21.3-23.32(chr10:69040366-93194993)x3	copy number gain	not provided [RCV000683289]	Chr10:69040366..93194993 [GRCh37] Chr10:10q21.3-23.32	pathogenic
GRCh37/hg19 10q23.31(chr10:92083015-92598823)x3	copy number gain	not provided [RCV000737258]	Chr10:92083015..92598823 [GRCh37] Chr10:10q23.31	benign
GRCh37/hg19 10q23.31(chr10:92617295-92617921)x1	copy number loss	not provided [RCV000737263]	Chr10:92617295..92617921 [GRCh37] Chr10:10q23.31	benign
GRCh37/hg19 10q23.31(chr10:92617295-92617927)x1	copy number loss	not provided [RCV000749763]	Chr10:92617295..92617927 [GRCh37] Chr10:10q23.31	benign
GRCh37/hg19 10q23.31(chr10:92617295-92618030)x1	copy number loss	not provided [RCV000749764]	Chr10:92617295..92618030 [GRCh37] Chr10:10q23.31	benign
GRCh37/hg19 10q23.31(chr10:92617295-92618082)x1	copy number loss	not provided [RCV000749765]	Chr10:92617295..92618082 [GRCh37] Chr10:10q23.31	benign
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3	copy number gain	not provided [RCV000749464]	Chr10:73232..135524321 [GRCh37] Chr10:10p15.3-q26.3	pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3	copy number gain	not provided [RCV000749465]	Chr10:98087..135477883 [GRCh37] Chr10:10p15.3-q26.3	pathogenic
NM_019859.4(HTR7):c.116C>G (p.Pro39Arg)	single nucleotide variant	Inborn genetic diseases [RCV003245585]	Chr10:90857556 [GRCh38] Chr10:92617313 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.701G>A (p.Ser234Asn)	single nucleotide variant	Inborn genetic diseases [RCV003271285]	Chr10:90749433 [GRCh38] Chr10:92509190 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.1343C>G (p.Pro448Arg)	single nucleotide variant	not provided [RCV000959117]	Chr10:90743643 [GRCh38] Chr10:92503400 [GRCh37] Chr10:10q23.31	benign
GRCh37/hg19 10q23.31(chr10:92079135-92600085)x3	copy number gain	not provided [RCV000848437]	Chr10:92079135..92600085 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q23.31(chr10:92085375-92605364)x3	copy number gain	not provided [RCV000849118]	Chr10:92085375..92605364 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q23.31(chr10:92077461-92605364)x3	copy number gain	not provided [RCV000847508]	Chr10:92077461..92605364 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.186G>T (p.Ala62=)	single nucleotide variant	not provided [RCV000903200]	Chr10:90857486 [GRCh38] Chr10:92617243 [GRCh37] Chr10:10q23.31	benign
GRCh37/hg19 10q23.31(chr10:92614401-92722894)x1	copy number loss	not provided [RCV001006345]	Chr10:92614401..92722894 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q23.31-23.33(chr10:89823147-96056941)x1	copy number loss	not provided [RCV002472645]	Chr10:89823147..96056941 [GRCh37] Chr10:10q23.31-23.33	pathogenic
GRCh37/hg19 10q23.1-23.32(chr10:82595472-93542416)x1	copy number loss	not provided [RCV002472429]	Chr10:82595472..93542416 [GRCh37] Chr10:10q23.1-23.32	pathogenic
NM_019859.4(HTR7):c.1165C>T (p.Arg389Trp)	single nucleotide variant	Inborn genetic diseases [RCV002974490]	Chr10:90748969 [GRCh38] Chr10:92508726 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.411C>A (p.Phe137Leu)	single nucleotide variant	Inborn genetic diseases [RCV002776676]	Chr10:90857261 [GRCh38] Chr10:92617018 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.1394A>G (p.Asp465Gly)	single nucleotide variant	Inborn genetic diseases [RCV002974331]	Chr10:90742528 [GRCh38] Chr10:92502285 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q23.31(chr10:92549833-92657760)x1	copy number loss	not provided [RCV002475526]	Chr10:92549833..92657760 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.50G>T (p.Arg17Leu)	single nucleotide variant	Inborn genetic diseases [RCV002910274]	Chr10:90857622 [GRCh38] Chr10:92617379 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.44A>G (p.His15Arg)	single nucleotide variant	Inborn genetic diseases [RCV002768340]	Chr10:90857628 [GRCh38] Chr10:92617385 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.193G>A (p.Asp65Asn)	single nucleotide variant	Inborn genetic diseases [RCV002989526]	Chr10:90857479 [GRCh38] Chr10:92617236 [GRCh37] Chr10:10q23.31	uncertain significance
NM_019859.4(HTR7):c.116C>A (p.Pro39Gln)	single nucleotide variant	Inborn genetic diseases [RCV002669589]	Chr10:90857556 [GRCh38] Chr10:92617313 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143)	copy number gain	Distal trisomy 10q [RCV003319593]	Chr10:11138692..135427143 [GRCh37] Chr10:10p14-q26.3	pathogenic
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143)	copy number loss	Distal 10q deletion syndrome [RCV003319583]	Chr10:12829206..135427143 [GRCh37] Chr10:10p13-q26.3	pathogenic
NM_019859.4(HTR7):c.343C>T (p.Pro115Ser)	single nucleotide variant	Inborn genetic diseases [RCV003369858]	Chr10:90857329 [GRCh38] Chr10:92617086 [GRCh37] Chr10:10q23.31	uncertain significance
GRCh37/hg19 10q11.21-24.2(chr10:42709645-100834951)x3	copy number gain	not provided [RCV003484798]	Chr10:42709645..100834951 [GRCh37] Chr10:10q11.21-24.2	pathogenic
GRCh37/hg19 10q23.31-24.2(chr10:90796994-100067505)x1	copy number loss	not specified [RCV003986861]	Chr10:90796994..100067505 [GRCh37] Chr10:10q23.31-24.2	pathogenic
GRCh37/hg19 10q23.31-23.32(chr10:89950990-92959893)x3	copy number gain	not specified [RCV003986875]	Chr10:89950990..92959893 [GRCh37] Chr10:10q23.31-23.32	uncertain significance
GRCh37/hg19 10q23.2-23.32(chr10:88121043-93641582)x1	copy number loss	not specified [RCV003986869]	Chr10:88121043..93641582 [GRCh37] Chr10:10q23.2-23.32	pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	2655
Count of miRNA genes:	557
Interacting mature miRNAs:	625
Transcripts:	ENST00000277874, ENST00000336152, ENST00000371719, ENST00000371721
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

D10S564

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	10	92,599,740 - 92,599,993	UniSTS	GRCh37
GRCh37	10	92,599,877 - 92,599,993	UniSTS	GRCh37
Build 36	10	92,589,720 - 92,589,973	RGD	NCBI36
Celera	10	86,346,322 - 86,346,436	UniSTS
Celera	10	86,346,185 - 86,346,436	RGD
Cytogenetic Map	10	q21-q24	UniSTS
HuRef	10	86,228,912 - 86,229,026	UniSTS
HuRef	10	86,228,775 - 86,229,026	UniSTS
Marshfield Genetic Map	10	112.58	UniSTS
Marshfield Genetic Map	10	112.58	RGD
Genethon Genetic Map	10	119.0	UniSTS
TNG Radiation Hybrid Map	10	44281.0	UniSTS
deCODE Assembly Map	10	110.74	UniSTS
Stanford-G3 RH Map	10	4149.0	UniSTS
GeneMap99-GB4 RH Map	10	436.66	UniSTS
Whitehead-YAC Contig Map	10		UniSTS
NCBI RH Map	10	1035.6	UniSTS
GeneMap99-G3 RH Map	10	4385.0	UniSTS

SHGC-132538

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	10	92,599,729 - 92,599,992	UniSTS	GRCh37
Build 36	10	92,589,709 - 92,589,972	RGD	NCBI36
Celera	10	86,346,174 - 86,346,435	RGD
Cytogenetic Map	10	q21-q24	UniSTS
HuRef	10	86,228,764 - 86,229,025	UniSTS
TNG Radiation Hybrid Map	10	44281.0	UniSTS

HTR7_1275

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	10	92,500,489 - 92,501,177	UniSTS	GRCh37
Build 36	10	92,490,469 - 92,491,157	RGD	NCBI36
Celera	10	86,246,921 - 86,247,609	RGD
HuRef	10	86,129,500 - 86,130,188	UniSTS

RH66814

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	10	92,508,665 - 92,508,804	UniSTS	GRCh37
Build 36	10	92,498,645 - 92,498,784	RGD	NCBI36
Celera	10	86,255,097 - 86,255,236	RGD
Cytogenetic Map	10	q21-q24	UniSTS
HuRef	10	86,137,676 - 86,137,815	UniSTS
GeneMap99-GB4 RH Map	10	438.37	UniSTS

HTR7

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	10	92,616,899 - 92,617,430	UniSTS	GRCh37
Celera	10	86,363,352 - 86,363,883	UniSTS
HuRef	10	86,245,905 - 86,246,436	UniSTS

D10S564

Human Assembly	Chr	Position (strand)	Source
Cytogenetic Map	10	q21-q24	UniSTS
TNG Radiation Hybrid Map	10	44281.0	UniSTS
Stanford-G3 RH Map	10	4149.0	UniSTS
GeneMap99-GB4 RH Map	10	436.66	UniSTS
NCBI RH Map	10	1035.6	UniSTS
GeneMap99-G3 RH Map	10	4385.0	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

High

Medium

186

280

Low

1018

1049

250

133

374

2491

467

1651

176

554

548

645

1615

Below cutoff

1315

1764

1356

417

1005

319

1656

1636

1916

185

558

966

100

554

1150

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NG_029218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_000872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_019859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_019860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024447973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054365712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB451482	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH005102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK292606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL360011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY493988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC047526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BG108256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L21195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U68487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U68488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X98147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X98193	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X98194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000277874 ⟹ ENSP00000277874

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	10	90,740,823 - 90,857,698 (-)	Ensembl

RefSeq Acc Id:

ENST00000336152 ⟹ ENSP00000337949

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	10	90,740,823 - 90,858,039 (-)	Ensembl

RefSeq Acc Id:

ENST00000371719 ⟹ ENSP00000360784

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	10	90,740,823 - 90,857,698 (-)	Ensembl

RefSeq Acc Id:

NM_000872 ⟹ NP_000863

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	10	90,740,823 - 90,858,039 (-)	NCBI
GRCh37	10	92,500,575 - 92,617,671 (-)	ENTREZGENE
Build 36	10	92,490,555 - 92,607,651 (-)	NCBI Archive
HuRef	10	86,129,586 - 86,246,677 (-)	ENTREZGENE
CHM1_1	10	92,778,457 - 92,895,518 (-)	NCBI
T2T-CHM13v2.0	10	91,624,488 - 91,741,713 (-)	NCBI

Sequence:

show sequence

GCACTCCGCAACTTCTGCCGCTGCCGCCCGGGCGCTCTCGGCGCAGCCGAGCTGCTGCTGCGAA
CTGTGGAGCTGCCAGCGGAGCCCAGCCCGAGCTCCCTCGACTCCGCGCGTCCCAGGCGTCCGTC
GGGGGCCGAAGCGCCTCCCGCAGGGAGTCCCCGTGAGGCCGCGCTGCCGCGTTACCCGCAGCGG
CCGGGGGTCCGGGGAGTGCGGGGCTCCGAGACAGAGCCAGGCGCCCCCCAGCGGTCGGCGCGGG
CCCCATGGCTGGGCCGGGCGGAGCGGAACCGGTGAGGTGAAGCCCCGGGGCCGGCAGCCGGAGG
CGCGTGGCCGGGGCGCCGGCTCCATGGGCAGCGGCACACGGCGGCGCGATGATGGACGTTAACA
GCAGCGGCCGCCCGGACCTCTACGGGCACCTCCGCTCTTTCCTTCTGCCAGAAGTGGGGCGCGG
GCTGCCCGACTTGAGCCCCGACGGTGGCGCCGACCCGGTCGCGGGCTCCTGGGCGCCGCACCTG
CTGAGCGAGGTGACAGCCAGCCCGGCGCCCACCTGGGACGCGCCCCCGGACAATGCCTCCGGCT
GTGGGGAACAGATCAACTACGGCAGAGTCGAGAAAGTTGTGATCGGCTCCATCCTGACGCTCAT
CACGCTGCTGACGATCGCGGGCAACTGCCTGGTGGTGATCTCCGTGTGCTTCGTCAAGAAGCTC
CGCCAGCCCTCCAACTACCTGATCGTGTCCCTGGCGCTGGCCGACCTCTCGGTGGCTGTGGCGG
TCATGCCCTTCGTCAGCGTCACCGACCTCATCGGGGGCAAGTGGATCTTTGGACACTTTTTCTG
TAATGTCTTCATCGCCATGGACGTCATGTGCTGCACGGCCTCGATCATGACCCTGTGCGTGATC
AGCATTGACAGGTACCTTGGGATCACAAGGCCCCTCACATACCCTGTGAGGCAGAATGGGAAAT
GCATGGCGAAGATGATTCTCTCCGTCTGGCTTCTCTCCGCCTCCATCACCTTACCTCCACTCTT
TGGATGGGCTCAGAATGTAAATGATGATAAGGTGTGCTTGATCAGCCAGGACTTTGGCTATACG
ATTTACTCTACCGCAGTGGCATTTTATATCCCCATGTCCGTCATGCTTTTCATGTACTACCAGA
TTTACAAGGCTGCCAGGAAGAGTGCTGCCAAACACAAGTTTCCTGGCTTCCCTCGAGTGGAGCC
AGACAGCGTCATCGCCCTGAATGGCATAGTGAAGCTCCAGAAGGAGGTGGAAGAGTGTGCAAAC
CTTTCGAGACTCCTCAAGCATGAAAGGAAAAACATCTCCATCTTTAAGCGAGAACAGAAAGCAG
CCACCACCCTGGGGATCATCGTCGGGGCCTTTACCGTGTGCTGGCTGCCATTTTTCCTCCTCTC
GACAGCCAGACCCTTCATCTGTGGCACTTCCTGCAGCTGCATCCCACTGTGGGTGGAGAGGACA
TTTCTGTGGCTAGGCTATGCAAACTCTCTCATTAACCCTTTTATATATGCCTTCTTCAACCGGG
ACCTGAGGACCACCTATCGCAGCCTGCTCCAGTGCCAGTACCGGAATATCAACCGGAAGCTCTC
AGCTGCAGGCATGCATGAAGCCCTGAAGCTTGCTGAGAGGCCAGAGAGACCTGAGTTTGTGCTA
CAAAATGCTGACTACTGTAGAAAAAAAGGTCATGATTCATGATTGAAAGCAGAACAATGGAGAT
GAAATAAACAAGGCAAAATAGAGGTGGAAACAGAAGGAAGTCATTTGCTGAGTCTGCAGAATGG
AATGCAGCTTCTGTCCTTTCTTGGGATGTCTAAAACATGACAAACAGGGTGATCTGTTGTACAC
ACTATCTTATGAGGGAGATGGTGACTTCTCCTTTTTTCTGTGGATCAGTGCTATTGTGTGTTCT
CAGTTTAAGATAGCAGATCATCTCAGCAGTAAGCACACCAACAGAACTGAGTTCCAGAAAGGAA
GCAGTTTCTGGTGCTTTGCATATGTCCAAATCCATGCAAGTGGGAGAAAGTTCCAGTGCACACT
TCCCATGCTTCTGAGTCTAGGCGTTGTGGTGAATATGCAGGAATCATTCATGAGACAGAATGTA
TTTTGTTGTATGACAGAAGGCTTTTCCAAGCAAACTGCGGTGAGCGTAGTGTTGAATATGTTGC
ATGTCCATGTTAGAAAACAGAATCCAGTCATCAGCTAATACAAATGATTTCCCAGAGCAGTGTT
TGTTTCAAGCTTCTGTCAAATAGTTTGGCTTTTCTGCAGGGTCTCTGTGATTTCCCCACCTATG
TACTTTTCTGTGTTAACTCACTTATTATGGTATAACTCAGGAACAGGTCTCAGGATGGAGAGAA
GCATACAACATGAGCAAAGCTTTTTCTCGTGCTCTGAAGGGTCTTGAGAGGGGAGTGGGATGCC
TTCTGTGAGGATTTTTATCGCAGTGAAGCTCAAGTGGTACCCAACTGCGTTGTAATTAACATGA
TTATTGGCATGTTTTTGACTCTCATTTTCTACAAGGCTGCAGTGGGCCCACCCATGGGCTGGCC
CATAACTGTATGTTATGTGGAAGAAGTGTGGGAATGATGGGTTTTCCATGAAATGTGATGCTTC
TGGAGATGGGGCATAAACATGTTCATTCTTGTTGAGCTGCATTGTGTTAAACCAAATTGTGTGA
AGCGAGGTCACCTGGACCACTCTTGGGAAATGCTTCAGAACACCAGTCTGTTCCTTCTAGAGAA
TTTGTTTTTGTGTTCTATGTATCTTAAATCAAATGTGTGCCTAAGCAATTCTGTCCTCTGATTC
CCACCCCTACCCACCAAAAAATGGTAGACATGAAAGGCAGGTGAGGAAACAGAAAAGGTCTCTT
TGCAGATATATATTTTTTAAATGGCACTATGTAGTAATTAAGAGCTAAGGAGACAGAAAGACAG
TAGATGAGAATAGAAGAGTACCTGTACCTACAAGGGGAAAAATGAATGCAATTCTTTATTTGAT
AAGAGTGAACTGAAAGAGAATATTATTTTCCTACAATAAAGCAAGCTGTCCTCTCACAGGATAA
AGTGGAATTCTGACATGGATTATGGACTTCTTCTAACTCCCATTGACATTGCTTCTTACCAGAC
ATGGGGAAAAGCTACCTTTCCTGAAAGGGGAGGAGGGCACTGTCCTTTCAGACAAAGCTTGTAC
AAATTCCTGAACCGCAAATTTGCTGAAGTGACCGTATATATTATATTCATAATTTAAATGATTA
TTTATGGTCAGATACATATTGTTAAACTTGAAAATGTTTTATTACATTACATCAAATAAAGTTT
ATTTGTAGCTGAAATAAAGCAACGTAAGTAACAATTTTTAA

hide sequence

RefSeq Acc Id:

NM_019859 ⟹ NP_062873

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	10	90,740,823 - 90,858,039 (-)	NCBI
GRCh37	10	92,500,575 - 92,617,671 (-)	ENTREZGENE
Build 36	10	92,490,555 - 92,607,651 (-)	NCBI Archive
HuRef	10	86,129,586 - 86,246,677 (-)	ENTREZGENE
CHM1_1	10	92,778,457 - 92,895,518 (-)	NCBI
T2T-CHM13v2.0	10	91,624,488 - 91,741,713 (-)	NCBI

Sequence:

show sequence

GCACTCCGCAACTTCTGCCGCTGCCGCCCGGGCGCTCTCGGCGCAGCCGAGCTGCTGCTGCGAA
CTGTGGAGCTGCCAGCGGAGCCCAGCCCGAGCTCCCTCGACTCCGCGCGTCCCAGGCGTCCGTC
GGGGGCCGAAGCGCCTCCCGCAGGGAGTCCCCGTGAGGCCGCGCTGCCGCGTTACCCGCAGCGG
CCGGGGGTCCGGGGAGTGCGGGGCTCCGAGACAGAGCCAGGCGCCCCCCAGCGGTCGGCGCGGG
CCCCATGGCTGGGCCGGGCGGAGCGGAACCGGTGAGGTGAAGCCCCGGGGCCGGCAGCCGGAGG
CGCGTGGCCGGGGCGCCGGCTCCATGGGCAGCGGCACACGGCGGCGCGATGATGGACGTTAACA
GCAGCGGCCGCCCGGACCTCTACGGGCACCTCCGCTCTTTCCTTCTGCCAGAAGTGGGGCGCGG
GCTGCCCGACTTGAGCCCCGACGGTGGCGCCGACCCGGTCGCGGGCTCCTGGGCGCCGCACCTG
CTGAGCGAGGTGACAGCCAGCCCGGCGCCCACCTGGGACGCGCCCCCGGACAATGCCTCCGGCT
GTGGGGAACAGATCAACTACGGCAGAGTCGAGAAAGTTGTGATCGGCTCCATCCTGACGCTCAT
CACGCTGCTGACGATCGCGGGCAACTGCCTGGTGGTGATCTCCGTGTGCTTCGTCAAGAAGCTC
CGCCAGCCCTCCAACTACCTGATCGTGTCCCTGGCGCTGGCCGACCTCTCGGTGGCTGTGGCGG
TCATGCCCTTCGTCAGCGTCACCGACCTCATCGGGGGCAAGTGGATCTTTGGACACTTTTTCTG
TAATGTCTTCATCGCCATGGACGTCATGTGCTGCACGGCCTCGATCATGACCCTGTGCGTGATC
AGCATTGACAGGTACCTTGGGATCACAAGGCCCCTCACATACCCTGTGAGGCAGAATGGGAAAT
GCATGGCGAAGATGATTCTCTCCGTCTGGCTTCTCTCCGCCTCCATCACCTTACCTCCACTCTT
TGGATGGGCTCAGAATGTAAATGATGATAAGGTGTGCTTGATCAGCCAGGACTTTGGCTATACG
ATTTACTCTACCGCAGTGGCATTTTATATCCCCATGTCCGTCATGCTTTTCATGTACTACCAGA
TTTACAAGGCTGCCAGGAAGAGTGCTGCCAAACACAAGTTTCCTGGCTTCCCTCGAGTGGAGCC
AGACAGCGTCATCGCCCTGAATGGCATAGTGAAGCTCCAGAAGGAGGTGGAAGAGTGTGCAAAC
CTTTCGAGACTCCTCAAGCATGAAAGGAAAAACATCTCCATCTTTAAGCGAGAACAGAAAGCAG
CCACCACCCTGGGGATCATCGTCGGGGCCTTTACCGTGTGCTGGCTGCCATTTTTCCTCCTCTC
GACAGCCAGACCCTTCATCTGTGGCACTTCCTGCAGCTGCATCCCACTGTGGGTGGAGAGGACA
TTTCTGTGGCTAGGCTATGCAAACTCTCTCATTAACCCTTTTATATATGCCTTCTTCAACCGGG
ACCTGAGGACCACCTATCGCAGCCTGCTCCAGTGCCAGTACCGGAATATCAACCGGAAGCTCTC
AGCTGCAGGCATGCATGAAGCCCTGAAGCTTGCTGAGAGGCCAGAGAGACCTGAGTTTGTGCTG
AGGGCCTGCACAAGGAGGGTGCTGTTGAGACCAGAAAAGAGGCCACCGGTATCTGTGTGGGTGC
TACAATCTCCAGACCATCACAATTGGTTAGCAGACAAAATGCTGACTACTGTAGAAAAAAAGGT
CATGATTCATGATTGAAAGCAGAACAATGGAGATGAAATAAACAAGGCAAAATAGAGGTGGAAA
CAGAAGGAAGTCATTTGCTGAGTCTGCAGAATGGAATGCAGCTTCTGTCCTTTCTTGGGATGTC
TAAAACATGACAAACAGGGTGATCTGTTGTACACACTATCTTATGAGGGAGATGGTGACTTCTC
CTTTTTTCTGTGGATCAGTGCTATTGTGTGTTCTCAGTTTAAGATAGCAGATCATCTCAGCAGT
AAGCACACCAACAGAACTGAGTTCCAGAAAGGAAGCAGTTTCTGGTGCTTTGCATATGTCCAAA
TCCATGCAAGTGGGAGAAAGTTCCAGTGCACACTTCCCATGCTTCTGAGTCTAGGCGTTGTGGT
GAATATGCAGGAATCATTCATGAGACAGAATGTATTTTGTTGTATGACAGAAGGCTTTTCCAAG
CAAACTGCGGTGAGCGTAGTGTTGAATATGTTGCATGTCCATGTTAGAAAACAGAATCCAGTCA
TCAGCTAATACAAATGATTTCCCAGAGCAGTGTTTGTTTCAAGCTTCTGTCAAATAGTTTGGCT
TTTCTGCAGGGTCTCTGTGATTTCCCCACCTATGTACTTTTCTGTGTTAACTCACTTATTATGG
TATAACTCAGGAACAGGTCTCAGGATGGAGAGAAGCATACAACATGAGCAAAGCTTTTTCTCGT
GCTCTGAAGGGTCTTGAGAGGGGAGTGGGATGCCTTCTGTGAGGATTTTTATCGCAGTGAAGCT
CAAGTGGTACCCAACTGCGTTGTAATTAACATGATTATTGGCATGTTTTTGACTCTCATTTTCT
ACAAGGCTGCAGTGGGCCCACCCATGGGCTGGCCCATAACTGTATGTTATGTGGAAGAAGTGTG
GGAATGATGGGTTTTCCATGAAATGTGATGCTTCTGGAGATGGGGCATAAACATGTTCATTCTT
GTTGAGCTGCATTGTGTTAAACCAAATTGTGTGAAGCGAGGTCACCTGGACCACTCTTGGGAAA
TGCTTCAGAACACCAGTCTGTTCCTTCTAGAGAATTTGTTTTTGTGTTCTATGTATCTTAAATC
AAATGTGTGCCTAAGCAATTCTGTCCTCTGATTCCCACCCCTACCCACCAAAAAATGGTAGACA
TGAAAGGCAGGTGAGGAAACAGAAAAGGTCTCTTTGCAGATATATATTTTTTAAATGGCACTAT
GTAGTAATTAAGAGCTAAGGAGACAGAAAGACAGTAGATGAGAATAGAAGAGTACCTGTACCTA
CAAGGGGAAAAATGAATGCAATTCTTTATTTGATAAGAGTGAACTGAAAGAGAATATTATTTTC
CTACAATAAAGCAAGCTGTCCTCTCACAGGATAAAGTGGAATTCTGACATGGATTATGGACTTC
TTCTAACTCCCATTGACATTGCTTCTTACCAGACATGGGGAAAAGCTACCTTTCCTGAAAGGGG
AGGAGGGCACTGTCCTTTCAGACAAAGCTTGTACAAATTCCTGAACCGCAAATTTGCTGAAGTG
ACCGTATATATTATATTCATAATTTAAATGATTATTTATGGTCAGATACATATTGTTAAACTTG
AAAATGTTTTATTACATTACATCAAATAAAGTTTATTTGTAGCTGAAATAAAGCAACGTAAGTA
ACAATTTTTAA

hide sequence

RefSeq Acc Id:

NM_019860 ⟹ NP_062874

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	10	90,740,823 - 90,858,039 (-)	NCBI
GRCh37	10	92,500,575 - 92,617,671 (-)	ENTREZGENE
Build 36	10	92,490,555 - 92,607,651 (-)	NCBI Archive
HuRef	10	86,129,586 - 86,246,677 (-)	ENTREZGENE
CHM1_1	10	92,778,457 - 92,895,518 (-)	NCBI
T2T-CHM13v2.0	10	91,624,488 - 91,741,713 (-)	NCBI

Sequence:

show sequence

GCACTCCGCAACTTCTGCCGCTGCCGCCCGGGCGCTCTCGGCGCAGCCGAGCTGCTGCTGCGAA
CTGTGGAGCTGCCAGCGGAGCCCAGCCCGAGCTCCCTCGACTCCGCGCGTCCCAGGCGTCCGTC
GGGGGCCGAAGCGCCTCCCGCAGGGAGTCCCCGTGAGGCCGCGCTGCCGCGTTACCCGCAGCGG
CCGGGGGTCCGGGGAGTGCGGGGCTCCGAGACAGAGCCAGGCGCCCCCCAGCGGTCGGCGCGGG
CCCCATGGCTGGGCCGGGCGGAGCGGAACCGGTGAGGTGAAGCCCCGGGGCCGGCAGCCGGAGG
CGCGTGGCCGGGGCGCCGGCTCCATGGGCAGCGGCACACGGCGGCGCGATGATGGACGTTAACA
GCAGCGGCCGCCCGGACCTCTACGGGCACCTCCGCTCTTTCCTTCTGCCAGAAGTGGGGCGCGG
GCTGCCCGACTTGAGCCCCGACGGTGGCGCCGACCCGGTCGCGGGCTCCTGGGCGCCGCACCTG
CTGAGCGAGGTGACAGCCAGCCCGGCGCCCACCTGGGACGCGCCCCCGGACAATGCCTCCGGCT
GTGGGGAACAGATCAACTACGGCAGAGTCGAGAAAGTTGTGATCGGCTCCATCCTGACGCTCAT
CACGCTGCTGACGATCGCGGGCAACTGCCTGGTGGTGATCTCCGTGTGCTTCGTCAAGAAGCTC
CGCCAGCCCTCCAACTACCTGATCGTGTCCCTGGCGCTGGCCGACCTCTCGGTGGCTGTGGCGG
TCATGCCCTTCGTCAGCGTCACCGACCTCATCGGGGGCAAGTGGATCTTTGGACACTTTTTCTG
TAATGTCTTCATCGCCATGGACGTCATGTGCTGCACGGCCTCGATCATGACCCTGTGCGTGATC
AGCATTGACAGGTACCTTGGGATCACAAGGCCCCTCACATACCCTGTGAGGCAGAATGGGAAAT
GCATGGCGAAGATGATTCTCTCCGTCTGGCTTCTCTCCGCCTCCATCACCTTACCTCCACTCTT
TGGATGGGCTCAGAATGTAAATGATGATAAGGTGTGCTTGATCAGCCAGGACTTTGGCTATACG
ATTTACTCTACCGCAGTGGCATTTTATATCCCCATGTCCGTCATGCTTTTCATGTACTACCAGA
TTTACAAGGCTGCCAGGAAGAGTGCTGCCAAACACAAGTTTCCTGGCTTCCCTCGAGTGGAGCC
AGACAGCGTCATCGCCCTGAATGGCATAGTGAAGCTCCAGAAGGAGGTGGAAGAGTGTGCAAAC
CTTTCGAGACTCCTCAAGCATGAAAGGAAAAACATCTCCATCTTTAAGCGAGAACAGAAAGCAG
CCACCACCCTGGGGATCATCGTCGGGGCCTTTACCGTGTGCTGGCTGCCATTTTTCCTCCTCTC
GACAGCCAGACCCTTCATCTGTGGCACTTCCTGCAGCTGCATCCCACTGTGGGTGGAGAGGACA
TTTCTGTGGCTAGGCTATGCAAACTCTCTCATTAACCCTTTTATATATGCCTTCTTCAACCGGG
ACCTGAGGACCACCTATCGCAGCCTGCTCCAGTGCCAGTACCGGAATATCAACCGGAAGCTCTC
AGCTGCAGGCATGCATGAAGCCCTGAAGCTTGCTGAGAGGCCAGAGAGACCTGAGTTTGTGCTG
TAAGACAAAATGCTGACTACTGTAGAAAAAAAGGTCATGATTCATGATTGAAAGCAGAACAATG
GAGATGAAATAAACAAGGCAAAATAGAGGTGGAAACAGAAGGAAGTCATTTGCTGAGTCTGCAG
AATGGAATGCAGCTTCTGTCCTTTCTTGGGATGTCTAAAACATGACAAACAGGGTGATCTGTTG
TACACACTATCTTATGAGGGAGATGGTGACTTCTCCTTTTTTCTGTGGATCAGTGCTATTGTGT
GTTCTCAGTTTAAGATAGCAGATCATCTCAGCAGTAAGCACACCAACAGAACTGAGTTCCAGAA
AGGAAGCAGTTTCTGGTGCTTTGCATATGTCCAAATCCATGCAAGTGGGAGAAAGTTCCAGTGC
ACACTTCCCATGCTTCTGAGTCTAGGCGTTGTGGTGAATATGCAGGAATCATTCATGAGACAGA
ATGTATTTTGTTGTATGACAGAAGGCTTTTCCAAGCAAACTGCGGTGAGCGTAGTGTTGAATAT
GTTGCATGTCCATGTTAGAAAACAGAATCCAGTCATCAGCTAATACAAATGATTTCCCAGAGCA
GTGTTTGTTTCAAGCTTCTGTCAAATAGTTTGGCTTTTCTGCAGGGTCTCTGTGATTTCCCCAC
CTATGTACTTTTCTGTGTTAACTCACTTATTATGGTATAACTCAGGAACAGGTCTCAGGATGGA
GAGAAGCATACAACATGAGCAAAGCTTTTTCTCGTGCTCTGAAGGGTCTTGAGAGGGGAGTGGG
ATGCCTTCTGTGAGGATTTTTATCGCAGTGAAGCTCAAGTGGTACCCAACTGCGTTGTAATTAA
CATGATTATTGGCATGTTTTTGACTCTCATTTTCTACAAGGCTGCAGTGGGCCCACCCATGGGC
TGGCCCATAACTGTATGTTATGTGGAAGAAGTGTGGGAATGATGGGTTTTCCATGAAATGTGAT
GCTTCTGGAGATGGGGCATAAACATGTTCATTCTTGTTGAGCTGCATTGTGTTAAACCAAATTG
TGTGAAGCGAGGTCACCTGGACCACTCTTGGGAAATGCTTCAGAACACCAGTCTGTTCCTTCTA
GAGAATTTGTTTTTGTGTTCTATGTATCTTAAATCAAATGTGTGCCTAAGCAATTCTGTCCTCT
GATTCCCACCCCTACCCACCAAAAAATGGTAGACATGAAAGGCAGGTGAGGAAACAGAAAAGGT
CTCTTTGCAGATATATATTTTTTAAATGGCACTATGTAGTAATTAAGAGCTAAGGAGACAGAAA
GACAGTAGATGAGAATAGAAGAGTACCTGTACCTACAAGGGGAAAAATGAATGCAATTCTTTAT
TTGATAAGAGTGAACTGAAAGAGAATATTATTTTCCTACAATAAAGCAAGCTGTCCTCTCACAG
GATAAAGTGGAATTCTGACATGGATTATGGACTTCTTCTAACTCCCATTGACATTGCTTCTTAC
CAGACATGGGGAAAAGCTACCTTTCCTGAAAGGGGAGGAGGGCACTGTCCTTTCAGACAAAGCT
TGTACAAATTCCTGAACCGCAAATTTGCTGAAGTGACCGTATATATTATATTCATAATTTAAAT
GATTATTTATGGTCAGATACATATTGTTAAACTTGAAAATGTTTTATTACATTACATCAAATAA
AGTTTATTTGTAGCTGAAATAAAGCAACGTAAGTAACAATTTTTAA

hide sequence

RefSeq Acc Id:

XM_024447973 ⟹ XP_024303741

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	10	90,740,823 - 90,777,196 (-)	NCBI

Sequence:

show sequence

GGAGGCATCTTAAGGCCACAGGTACCTTGGGATCACAAGGCCCCTCACATACCCTGTGAGGCAG
AATGGGAAATGCATGGCGAAGATGATTCTCTCCGTCTGGCTTCTCTCCGCCTCCATCACCTTAC
CTCCACTCTTTGGATGGGCTCAGAATGTAAATGATGATAAGGTGTGCTTGATCAGCCAGGACTT
TGGCTATACGATTTACTCTACCGCAGTGGCATTTTATATCCCCATGTCCGTCATGCTTTTCATG
TACTACCAGATTTACAAGGCTGCCAGGAAGAGTGCTGCCAAACACAAGTTTCCTGGCTTCCCTC
GAGTGGAGCCAGACAGCGTCATCGCCCTGAATGGCATAGTGAAGCTCCAGAAGGAGGTGGAAGA
GTGTGCAAACCTTTCGAGACTCCTCAAGCATGAAAGGAAAAACATCTCCATCTTTAAGCGAGAA
CAGAAAGCAGCCACCACCCTGGGGATCATCGTCGGGGCCTTTACCGTGTGCTGGCTGCCATTTT
TCCTCCTCTCGACAGCCAGACCCTTCATCTGTGGCACTTCCTGCAGCTGCATCCCACTGTGGGT
GGAGAGGACATTTCTGTGGCTAGGCTATGCAAACTCTCTCATTAACCCTTTTATATATGCCTTC
TTCAACCGGGACCTGAGGACCACCTATCGCAGCCTGCTCCAGTGCCAGTACCGGAATATCAACC
GGAAGCTCTCAGCTGCAGGCATGCATGAAGCCCTGAAGCTTGCTGAGAGGCCAGAGAGACCTGA
GTTTGTGCTGAGGGCCTGCACAAGGAGGGTGCTGTTGAGACCAGAAAAGAGGCCACCGGTATCT
GTGTGGGTGCTACAATCTCCAGACCATCACAATTGGTTAGCAGACAAAATGCTGACTACTGTAG
AAAAAAAGGTCATGATTCATGATTGAAAGCAGAACAATGGAGATGAAATAAACAAGGCAAAATA
GAGGTGGAAACAGAAGGAAGTCATTTGCTGAGTCTGCAGAATGGAATGCAGCTTCTGTCCTTTC
TTGGGATGTCTAAAACATGACAAACAGGGTGATCTGTTGTACACACTATCTTATGAGGGAGATG
GTGACTTCTCCTTTTTTCTGTGGATCAGTGCTATTGTGTGTTCTCAGTTTAAGATAGCAGATCA
TCTCAGCAGTAAGCACACCAACAGAACTGAGTTCCAGAAAGGAAGCAGTTTCTGGTGCTTTGCA
TATGTCCAAATCCATGCAAGTGGGAGAAAGTTCCAGTGCACACTTCCCATGCTTCTGAGTCTAG
GCGTTGTGGTGAATATGCAGGAATCATTCATGAGACAGAATGTATTTTGTTGTATGACAGAAGG
CTTTTCCAAGCAAACTGCGGTGAGCGTAGTGTTGAATATGTTGCATGTCCATGTTAGAAAACAG
AATCCAGTCATCAGCTAATACAAATGATTTCCCAGAGCAGTGTTTGTTTCAAGCTTCTGTCAAA
TAGTTTGGCTTTTCTGCAGGGTCTCTGTGATTTCCCCACCTATGTACTTTTCTGTGTTAACTCA
CTTATTATGGTATAACTCAGGAACAGGTCTCAGGATGGAGAGAAGCATACAACATGAGCAAAGC
TTTTTCTCGTGCTCTGAAGGGTCTTGAGAGGGGAGTGGGATGCCTTCTGTGAGGATTTTTATCG
CAGTGAAGCTCAAGTGGTACCCAACTGCGTTGTAATTAACATGATTATTGGCATGTTTTTGACT
CTCATTTTCTACAAGGCTGCAGTGGGCCCACCCATGGGCTGGCCCATAACTGTATGTTATGTGG
AAGAAGTGTGGGAATGATGGGTTTTCCATGAAATGTGATGCTTCTGGAGATGGGGCATAAACAT
GTTCATTCTTGTTGAGCTGCATTGTGTTAAACCAAATTGTGTGAAGCGAGGTCACCTGGACCAC
TCTTGGGAAATGCTTCAGAACACCAGTCTGTTCCTTCTAGAGAATTTGTTTTTGTGTTCTATGT
ATCTTAAATCAAATGTGTGCCTAAGCAATTCTGTCCTCTGATTCCCACCCCTACCCACCAAAAA
ATGGTAGACATGAAAGGCAGGTGAGGAAACAGAAAAGGTCTCTTTGCAGATATATATTTTTTAA
ATGGCACTATGTAGTAATTAAGAGCTAAGGAGACAGAAAGACAGTAGATGAGAATAGAAGAGTA
CCTGTACCTACAAGGGGAAAAATGAATGCAATTCTTTATTTGATAAGAGTGAACTGAAAGAGAA
TATTATTTTCCTACAATAAAGCAAGCTGTCCTCTCACAGGATAAAGTGGAATTCTGACATGGAT
TATGGACTTCTTCTAACTCCCATTGACATTGCTTCTTACCAGACATGGGGAAAAGCTACCTTTC
CTGAAAGGGGAGGAGGGCACTGTCCTTTCAGACAAAGCTTGTACAAATTCCTGAACCGCAAATT
TGCTGAAGTGACCGTATATATTATATTCATAATTTAAATGATTATTTATGGTCAGATACATATT
GTTAAACTTGAAAATGTTTTATTACATTACATCAAATAAAGTTTATTTGTAGCTGAAATAAAGC
AACGTAAGTAACAATTTTTAATTAAAGGTCTTATGTCATACATGTTGCTGTCTGTAGAATGGCT
GAAGGGCAGACATTTTACGTGTTTGCTAAAATCCTAACAGGTAGCTAAGACAGCTCTGGTTTCA
ATTCCATTTCACTGTGGATTCATTCACTTAGTGACTTTATTTTTATAAAACAATGACTGTTCAT
TACTTGATCTGATTAATGAGCATTGTTTGGGCTCCTGGCACATTAGCATTGCTGGCATCAAGGG
GACAAAGATGGGTATGGCACAGTCCTTGCTTTTAAGAGTTTGCCATCAGGTAGAAGGCAAACAT
GTCTCGATTTGTCACAATATAGTATAGTAAGTGCTGTAACAGGTTTTAGGGAGTGACTTTTTCT
TTCCTGTAGTGTAAGACAGGGCACTATGGTTAGTTGGATTGATTCAGGTTTTCAAATGTGTTGT
TTAATTTTTTATTAAGACCTTCATGATTCATATTGGCTCCTTATCCTGCCTGACTTGAATGCCC
GACTATTGACCTCTCTGCTTCATTCTGGCTATAGAGGCTGAGCTTCATGTGTAGACTGTACTTT
AAATATACAGCAGCAAATAAAAGGAAAAGGTAGAAATCGAAAGGGGATGAGAAAAATAAATCAT
TAATACAGTTTCACATATGACATAATTTGTGCCAAAGACACAGCTTTTGTTTTAACTAAGAATT
GGGAAAATCATTGAAATGAACATTTTATATATAATGACTGTTCAAGCAAGAAGGACTATTCCTC
TTCTCACTCTATGGTATCAGCTGTCATTTTCTGGCAAGGCTGAGTACTGGGAAACCATGCTTGA
GAAGTAAAGCACTTACTTGTAAGAGATAACTGAATCACTGTTGCCTTAGCTTTTAGTTTTATTC
TGTAAATATTAAACAGGAGACACTCAGAGTTCCTCGATTTTCTAGCAACTGTTTCATAACTGAA
AGCATTGATTATGTTGTCATGGACTTGATATGCTTGTGCATGTATTTGATGATCATATTTTCAT
ATAGTTTTATTAGGTTCATTGATTGCAGGCAGTGGGTCAAAAATATGAATGGAAAATGCAGGTA
ATTTTTTCAAATAGTTTATGCTAATATAATAATTGAATTACCATCTGGAGATAGTGGGAATTTC
CCTTTCAGCATTTTCATTGTCAATTTAGTTTTCAATTTAATGGCTATAAATGTTGCTAAATACT
GGAGTCTTGAAAAATTGTTCATGCTCCTTCTGATCTCAGGACCTTCACACATGCTTTCCCTCTT
GGTTTGTGATATTCCTCCTGATCTCATTTATTTGATGTATGCCTTCATTATCATCCAGTAAATC
TTCAAGGGTAGGGGCCATGTCTGTTTTTCTCAACAATATGCCCATTACCTAGCACCATGCTGGG
AACATATATATGGTAGGCCAACAATGGGTATGTTTTAATGAGAAGGAGGGAGGGAAGGAGAGAG
AGGCAAGAGTTCACTGGCACTTTTTAAAAATGTTTATATGAGGAAACAAAGAAGACTTGCTGTG
ATCCAGCGACATGCCCAGTGAGTGGAAGAGAAGAAACTGGAATTAAGCTATTCTGTGTGCCACT
TAGGTCAGGCCCTCCACTACATGGTCCTGCTTCTCTTGCATGAGTTAGCTACTCATATCATGAG
AGCATCCCTTTCTTAATTTTCTGCGCTAGTGGAGCAGAGCCATGTATGTGCTATGGCCCATATG
TTGAAACTTGTTTATCTACAGCTAGCCAGATGGTCTGTAACAGCACACAAAGAAGCCATTTGGA
AACTTTCAGAGGGTCAGCACGTTTTGAAAACAACTCAGAGTAATGCATATTGTGATGTCATTGC
TTACTTTAAGCTTACAGTGAGGAATATCTTGTTAGGTACTGAATGTGAAACATGCAGACTTTGA
GAACCAACTCAGAGGTCCTAGCCCCCAGAGACAGAAATTTATTTAATTGGATCACCCTTTAGAC
TTGTTTTGTCTACATGTTCTCTGAAAAAGGAATATAATGTCTTAATTTAAAATACTTTGTTTTT
TAAGTTGCTGCTGGGTTAAATACATTTTTTTTTAAAGAAAACCTGCTTATGCAGTACATGTTAA
CAGATATGATGTGGTCATCAATAAAAATGTAAAATAAAA

hide sequence

RefSeq Acc Id:

XM_054365712 ⟹ XP_054221687

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	10	91,624,488 - 91,660,873 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_000863	(Get FASTA)	NCBI Sequence Viewer
	NP_062873	(Get FASTA)	NCBI Sequence Viewer
	NP_062874	(Get FASTA)	NCBI Sequence Viewer
	XP_024303741	(Get FASTA)	NCBI Sequence Viewer
	XP_054221687	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB48393	(Get FASTA)	NCBI Sequence Viewer
	AAB48394	(Get FASTA)	NCBI Sequence Viewer
	AAB48397	(Get FASTA)	NCBI Sequence Viewer
	AAC37538	(Get FASTA)	NCBI Sequence Viewer
	AAF07217	(Get FASTA)	NCBI Sequence Viewer
	AAF07218	(Get FASTA)	NCBI Sequence Viewer
	AAH47526	(Get FASTA)	NCBI Sequence Viewer
	AAR87480	(Get FASTA)	NCBI Sequence Viewer
	BAF85295	(Get FASTA)	NCBI Sequence Viewer
	BAG70296	(Get FASTA)	NCBI Sequence Viewer
	CAA66865	(Get FASTA)	NCBI Sequence Viewer
	EAW50118	(Get FASTA)	NCBI Sequence Viewer
	EAW50119	(Get FASTA)	NCBI Sequence Viewer
	EAW50120	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000277874
	ENSP00000277874.6
	ENSP00000337949
	ENSP00000337949.3
	ENSP00000360784
	ENSP00000360784.2
GenBank Protein	P34969	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_000863 ⟸ NM_000872
- Peptide Label:	isoform a
- UniProtKB:	P34969 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPP DNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADL SVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV RQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVML FMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFK REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIY AFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLQNADYCRKKGHDS hide sequence

RefSeq Acc Id:	NP_062873 ⟸ NM_019859
- Peptide Label:	isoform d
- UniProtKB:	Q5VX02 (UniProtKB/Swiss-Prot), Q5VX01 (UniProtKB/Swiss-Prot), P78516 (UniProtKB/Swiss-Prot), P78372 (UniProtKB/Swiss-Prot), P78336 (UniProtKB/Swiss-Prot), B5BUP6 (UniProtKB/Swiss-Prot), Q5VX03 (UniProtKB/Swiss-Prot), P34969 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPP DNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADL SVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV RQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVML FMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFK REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIY AFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPP VSVWVLQSPDHHNWLADKMLTTVEKKVMIHD hide sequence

RefSeq Acc Id:	NP_062874 ⟸ NM_019860
- Peptide Label:	isoform b
- UniProtKB:	P34969 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPP DNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADL SVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV RQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVML FMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFK REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIY AFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVL hide sequence

RefSeq Acc Id:

XP_024303741 ⟸ XM_024447973

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQI
YKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAA
TTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRD
LRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVL
QSPDHHNWLADKMLTTVEKKVMIHD

hide sequence

RefSeq Acc Id:

ENSP00000360784 ⟸ ENST00000371719

RefSeq Acc Id:

ENSP00000337949 ⟸ ENST00000336152

RefSeq Acc Id:

ENSP00000277874 ⟸ ENST00000277874

RefSeq Acc Id:	XP_054221687 ⟸ XM_054365712
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P34969-F1-model_v2	AlphaFold	P34969	1-479	view protein structure

Promoters

RGD ID:

7218123

Promoter ID:

EPDNEW_H14806

Type:

initiation region

Name:

HTR7_1

Description:

5-hydroxytryptamine receptor 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	10	90,857,750 - 90,857,810	EPDNEW

RGD ID:

6787592

Promoter ID:

HG_KWN:10524

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, HeLa_S3, NB4

Transcripts:

ENST00000394281

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	10	92,607,006 - 92,607,747 (-)	MPROMDB

RGD ID:

6787769

Promoter ID:

HG_KWN:10525

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

K562

Transcripts:

ENST00000371721, UC001KGZ.1, UC001KHA.1, UC001KHB.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	10	92,607,346 - 92,607,846 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:5302	AgrOrtholog
COSMIC	HTR7	COSMIC
Ensembl Genes	ENSG00000148680	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000277874	ENTREZGENE
	ENST00000277874.10	UniProtKB/Swiss-Prot
	ENST00000336152	ENTREZGENE
	ENST00000336152.8	UniProtKB/Swiss-Prot
	ENST00000371719	ENTREZGENE
	ENST00000371719.2	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
GTEx	ENSG00000148680	GTEx
HGNC ID	HGNC:5302	ENTREZGENE
Human Proteome Map	HTR7	Human Proteome Map
InterPro	5HT_7_rcpt	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
KEGG Report	hsa:3363	UniProtKB/Swiss-Prot
NCBI Gene	3363	ENTREZGENE
OMIM	182137	OMIM
PANTHER	5-HYDROXYTRYPTAMINE RECEPTOR	UniProtKB/Swiss-Prot
	5-HYDROXYTRYPTAMINE RECEPTOR 7	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PharmGKB	PA29561	PharmGKB
PRINTS	5HT7RECEPTR	UniProtKB/Swiss-Prot
	GPCRRHODOPSN	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot
UniProt	5HT7R_HUMAN	UniProtKB/Swiss-Prot
	B5BUP6	ENTREZGENE
	P34969	ENTREZGENE
	P78336	ENTREZGENE
	P78372	ENTREZGENE
	P78516	ENTREZGENE
	Q5VX01	ENTREZGENE
	Q5VX02	ENTREZGENE
	Q5VX03	ENTREZGENE
UniProt Secondary	B5BUP6	UniProtKB/Swiss-Prot
	P78336	UniProtKB/Swiss-Prot
	P78372	UniProtKB/Swiss-Prot
	P78516	UniProtKB/Swiss-Prot
	Q5VX01	UniProtKB/Swiss-Prot
	Q5VX02	UniProtKB/Swiss-Prot
	Q5VX03	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-10	HTR7	5-hydroxytryptamine receptor 7	HTR7	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	Symbol and/or name change	5135510	APPROVED
2012-03-13	HTR7	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB