Gene: UGT1A5 (UDP glucuronosyltransferase 1 family, polypeptide A5)  Homo sapiens
Symbol: UGT1A5
Name: UDP glucuronosyltransferase 1 family, polypeptide A5
Description: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: OTTHUMP00000065195; OTTHUMP00000065199; UDP glycosyltransferase 1 family, polypeptide A5; UDP-glucuronosyltransferase 1 family polypeptide A5s; UDP-glucuronosyltransferase 1-5; UDP-glucuronosyltransferase 1-E; UDP-glucuronosyltransferase 1A5; UDPGT; UDPGT 1-5; UGT-1E; UGT1*5; UGT1E
Orthologs: Mus musculus : Ugt1a5 (UDP glucuronosyltransferase 1 family, polypeptide A5)  MGI
Rattus norvegicus : Ugt1a5 (UDP glucuronosyltransferase 1 family, polypeptide A5)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_12233,994,249 - 234,054,578+NCBI
Human Genome Assembly HuRef2226,421,632 - 226,481,779+NCBI
Human Genome Assembly GRCh372234,621,638 - 234,681,945+NCBI
Human Celera Assembly2228,342,257 - 228,402,577+NCBI
Human Genome Assembly Build 362234,286,377 - 234,346,684+NCBI
Human Cytogenetic Map2q37 NCBI
Human Genome Assembly2234,403,637 - 234,463,945 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)

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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
  
More on UGT1A5
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1346830
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2013-02-27
Status: ACTIVE



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