Crb1<sup>m1</sup> (crumbs 1, cell polarity complex component, mutant 1) - Rat Genome Database

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Gene: Crb1m1 (crumbs 1, cell polarity complex component, mutant 1) Rattus norvegicus
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Symbol: Crb1m1
Name: crumbs 1, cell polarity complex component, mutant 1
RGD ID: 13451133
Description: A deletion insertion mutation (c.1685_1698delinsCAAGATGG) in exon 6 of the rat crb1 was identified to be responsible for the retinal phenotype of BN-Crb1m1 (RGD:13451132).
ASSOCIATED WITH abnormal Muller cell morphology; abnormal retina pigmentation; disorganized retina outer nuclear layer; ASSOCIATED WITH Idiopathic Juxtafoveal Retinal Telangiectasia
Type: allele  of Crb1  
Previously known as: Crb1^[m1]; Crb1m1; crumbs 1, cell polarity complex component;mutant 1
Is Marker For: Strains:   BN-Crb1m1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. A new CRB1 rat mutation links Müller glial cells to retinal telangiectasia. Zhao M, etal., J Neurosci. 2015 Apr 15;35(15):6093-106. doi: 10.1523/JNEUROSCI.3412-14.2015.

Genomics


Related Rat Strains
The following Strains have been annotated to Crb1m1
BN-Crb1m1    


Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-03 Crb1m1  crumbs 1, cell polarity complex component, mutant 1  Crb1m1  crumbs 1, cell polarity complex component;mutant 1  Name changed 629549 APPROVED