Gene: WDR24 (WD repeat domain 24)
Homo sapiens
Symbol:
WDR24
Name:
WD repeat domain 24
Description:
ENCODES a protein that exhibits peroxisome matrix targeting signal-2 binding (inferred); INVOLVED IN protein import into peroxisome matrix (inferred); FOUND IN peroxisome (inferred); INTERACTS WITH benzo[a]pyrene; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 2,4,6-trinitrotoluene (ortholog)
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
C16orf21; DKFZp434F054; JFP7; OTTHUMP00000115488; WD repeat-containing protein 24
Orthologs:
Mus musculus : Wdr24
(WD repeat domain 24)
MGI
Rattus norvegicus : Wdr24
(WD repeat domain 24)
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 16 672,344 - 678,042 - NCBI Human Genome Assembly HuRef 16 656,579 - 662,277 - NCBI Human Genome Assembly GRCh37 16 734,702 - 740,400 - NCBI Human Celera Assembly 16 934,859 - 940,557 - NCBI Human Genome Assembly Build 36 16 674,703 - 680,401 - NCBI Human Cytogenetic Map 16 p13.3 NCBI Human Genome Assembly 16 674,702 - 680,401 NCBI
Model
Gene-Chemical Interaction Annotations
2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1551186 6480464 Tetrachlorodibenzodioxin affects the expression of WDR24 mRNA CTD PMID:21570461 2,4,6-trinitrotoluene affects expression ISO RGD:1304803 6480464 Trinitrotoluene affects the expression of WDR24 mRNA CTD PMID:21346803 2,4-dinitrotoluene affects expression ISO RGD:1304803 6480464 2,4-dinitrotoluene affects the expression of WDR24 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression ISO RGD:1304803 6480464 2,6-dinitrotoluene affects the expression of WDR24 mRNA CTD PMID:21346803 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1551186 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of WDR24 mRNA CTD PMID:20188158 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of WDR24 mRNA CTD PMID:20106945
Gene Ontology Annotations
Biological Process
protein import into peroxisome matrix IEA InterPro:IPR025651 2290271 GO_REF:0000002 InterPro GO_REF:0000002
1358837 MULTSCL9_H Multiple sclerosis susceptibility QTL 9 (human) Multiple sclerosis susceptibility 16 1 16709764 Human 2314553 INSUL3_H Insulin level QTL 3 (human) 2.8 .00048 Insulin level fasting 16 1 16709764 Human 2316049 GLUCO211_H Glucose level QTL 211 (human) .039 Glucose level 16 1 19043306 Human 1559367 BW47_H Body weight QTL 47 (human) 3.12 .00025 Body weight body mass index 16 1 22718456 Human 2292990 PRSTS147_H Prostate tumor susceptibility QTL 147 (human) 5.69 .000022 Prostate tumor susceptibility 16 1 22718456 Human 2315775 GLUCO145_H Glucose level QTL 145 (human) 1.15 .01796 Glucose level 16 1 23277455 Human 2289195 SLEP12_H Serum leptin level QTL 12 (human) 1.72 .0024 Hormone level leptin 16 1 23277455 Human 1578593 SCL134_H Serum cholesterol level QTL 134 (human) 2.1 Lipid level total cholesterol 16 1 25139539 Human 2293366 PRSTS233_H Prostate tumor susceptibility QTL 233 (human) 1.22 Prostate tumor susceptibility 16 1 25139539 Human 2293415 PRSTS232_H Prostate tumor susceptibility QTL 232 (human) 1.58 Prostate tumor susceptibility 16 1 25139539 Human