Gene: NAT1 (N-acetyltransferase 1 (arylamine N-acetyltransferase))  Homo sapiens
Symbol: NAT1
Name: N-acetyltransferase 1 (arylamine N-acetyltransferase)
Description: This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AAC1; arylamide acetylase 1; arylamine N-acetyltransferase 1; MNAT; monomorphic arylamine N-acetyltransferase; N-acetyltransferase type 1; NAT-1; NATI; OTTHUMP00000122488; OTTHUMP00000224577; OTTHUMP00000224578; OTTHUMP00000224579
Orthologs: Mus musculus : Nat2 (N-acetyltransferase 2 (arylamine N-acetyltransferase))  MGI
Rattus norvegicus : Nat1 (N-acetyltransferase 1 (arylamine N-acetyltransferase))
Latest Assembly: Human Genome Assembly GRCh37
NCBI Annotation Information: Note: Loci in other organisms that are functionally homologous to this one are validly referred to as both NAT1 and NAT2; i.e., the functional homologs of NAT1 include mouse and rat Nat2, while the functional homologs of human NAT2 include mouse and rat Nat1. Name:sequence associations are consistent with current use in the field. [27 Apr 2009]
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1818,282,847 - 18,336,068+NCBI
Human Genome Assembly HuRef816,572,274 - 16,625,520+NCBI
Human Genome Assembly GRCh37818,027,971 - 18,081,198+NCBI
Human Genome Assembly Build 36818,111,895 - 18,125,100+NCBI
Human Cytogenetic Map8p22 NCBI
Human Genome Assembly818,111,894 - 18,125,099 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

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Genomics

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Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
  
More on NAT1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
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Vista
Vista + UCSC

RGD Object Information
RGD ID: 1344668
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE



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