MADCAM1 (mucosal vascular addressin cell adhesion molecule 1)

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Keyword

Gene: MADCAM1 (mucosal vascular addressin cell adhesion molecule 1) Homo sapiens

Symbol:

MADCAM1

Name:

mucosal vascular addressin cell adhesion molecule 1

Description:

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

hMAdCAM-1; MACAM1; MAdCAM-1; mucosal addressin cell adhesion molecule 1; mucosal addressin cell adhesion molecule-1

Orthologs:

Mus musculus : Madcam1 (mucosal vascular addressin cell adhesion molecule 1) MGI
Rattus norvegicus : Madcam1 (mucosal vascular addressin cell adhesion molecule 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	19	428,463 - 437,761	+	NCBI
Human Genome Assembly HuRef	19	266,619 - 275,499	+	NCBI
Human Genome Assembly GRCh37	19	496,490 - 505,343	+	NCBI
Human Genome Assembly Build 36	19	447,490 - 456,343	+	NCBI
Human Cytogenetic Map	19	p13.3		NCBI
Human Genome Assembly	19	447,489 - 456,342		NCBI