ACSM6 (acyl-CoA synthetase medium chain family member 6) - Rat Genome Database

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Gene: ACSM6 (acyl-CoA synthetase medium chain family member 6) Homo sapiens
Analyze
Symbol: ACSM6
Name: acyl-CoA synthetase medium chain family member 6
RGD ID: 1344514
HGNC Page HGNC:31665
Description: Predicted to enable fatty acid ligase activity and fatty-acyl-CoA synthase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: acyl-CoA synthetase medium-chain family member 6; acyl-coenzyme A synthetase ACSM6, mitochondrial; AMP-binding enzyme; bA310E22.3; C10orf129
RGD Orthologs
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: AC018653.2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381095,194,238 - 95,228,929 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1095,194,200 - 95,228,929 (+)EnsemblGRCh38hg38GRCh38
GRCh371096,953,995 - 96,988,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361096,943,947 - 96,976,152 (+)NCBINCBI36Build 36hg18NCBI36
Build 341096,943,946 - 96,976,152NCBI
Celera1090,695,101 - 90,729,842 (+)NCBICelera
Cytogenetic Map10q23.33NCBI
HuRef1090,581,065 - 90,615,820 (+)NCBIHuRef
CHM1_11097,235,716 - 97,270,449 (+)NCBICHM1_1
T2T-CHM13v2.01096,073,280 - 96,108,083 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16385451   PMID:21873635   PMID:23884467   PMID:24270810  


Genomics

Comparative Map Data
ACSM6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381095,194,238 - 95,228,929 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1095,194,200 - 95,228,929 (+)EnsemblGRCh38hg38GRCh38
GRCh371096,953,995 - 96,988,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361096,943,947 - 96,976,152 (+)NCBINCBI36Build 36hg18NCBI36
Build 341096,943,946 - 96,976,152NCBI
Celera1090,695,101 - 90,729,842 (+)NCBICelera
Cytogenetic Map10q23.33NCBI
HuRef1090,581,065 - 90,615,820 (+)NCBIHuRef
CHM1_11097,235,716 - 97,270,449 (+)NCBICHM1_1
T2T-CHM13v2.01096,073,280 - 96,108,083 (+)NCBIT2T-CHM13v2.0
ACSM6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28107,093,668 - 107,127,530 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110107,098,986 - 107,132,848 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01091,800,561 - 91,834,123 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11095,309,060 - 95,341,767 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1095,309,060 - 95,341,767 (+)Ensemblpanpan1.1panPan2
LOC103231985
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X47,865,823 - 47,877,119 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660861,486,553 - 1,501,012 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ACSM6
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q23.33-25.3(chr10:95112607-116776637)x3 copy number gain See cases [RCV000050747] Chr10:95112607..116776637 [GRCh38]
Chr10:96872364..118383651 [GRCh37]
Chr10:96862354..118526138 [NCBI36]
Chr10:10q23.33-25.3
pathogenic
GRCh38/hg38 10q23.33-24.1(chr10:94872737-95346558)x3 copy number gain See cases [RCV000051183] Chr10:94872737..95346558 [GRCh38]
Chr10:96632494..97106315 [GRCh37]
Chr10:96622484..97096305 [NCBI36]
Chr10:10q23.33-24.1
uncertain significance
GRCh38/hg38 10q23.33-24.2(chr10:92626680-97755102)x1 copy number loss See cases [RCV000052564] Chr10:92626680..97755102 [GRCh38]
Chr10:94386437..99514859 [GRCh37]
Chr10:94376417..99504849 [NCBI36]
Chr10:10q23.33-24.2
pathogenic
GRCh38/hg38 10q23.33-24.32(chr10:93181201-101356779)x1 copy number loss See cases [RCV000052565] Chr10:93181201..101356779 [GRCh38]
Chr10:94940958..103116536 [GRCh37]
Chr10:94930948..103106526 [NCBI36]
Chr10:10q23.33-24.32
pathogenic
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3
pathogenic
NM_207321.2(ACSM6):c.928C>T (p.Pro310Ser) single nucleotide variant Malignant melanoma [RCV000069107] Chr10:95212873 [GRCh38]
Chr10:96972630 [GRCh37]
Chr10:96962620 [NCBI36]
Chr10:10q23.33
not provided
NM_207321.2(ACSM6):c.995+1963C>T (p.Ser349=) single nucleotide variant Malignant melanoma [RCV000069108] Chr10:95214903 [GRCh38]
Chr10:96974660 [GRCh37]
Chr10:96964650 [NCBI36]
Chr10:10q23.33
not provided
GRCh38/hg38 10q23.33(chr10:94298267-95267990)x1 copy number loss See cases [RCV000134773] Chr10:94298267..95267990 [GRCh38]
Chr10:96058024..97027747 [GRCh37]
Chr10:96048014..97017737 [NCBI36]
Chr10:10q23.33
uncertain significance
GRCh38/hg38 10q23.33-24.1(chr10:94401557-95444828)x3 copy number gain See cases [RCV000137970] Chr10:94401557..95444828 [GRCh38]
Chr10:96161314..97204585 [GRCh37]
Chr10:96151304..97194575 [NCBI36]
Chr10:10q23.33-24.1
uncertain significance
GRCh38/hg38 10q23.33-24.1(chr10:92643919-95471137)x1 copy number loss See cases [RCV000137919] Chr10:92643919..95471137 [GRCh38]
Chr10:94403676..97230894 [GRCh37]
Chr10:94393656..97220884 [NCBI36]
Chr10:10q23.33-24.1
pathogenic
GRCh38/hg38 10q23.33-24.1(chr10:94376979-95466604)x3 copy number gain See cases [RCV000142079] Chr10:94376979..95466604 [GRCh38]
Chr10:96136736..97226361 [GRCh37]
Chr10:96126726..97216351 [NCBI36]
Chr10:10q23.33-24.1
uncertain significance
GRCh37/hg19 10q23.33-24.1(chr10:94393383-97219175) copy number loss not provided [RCV000767566] Chr10:94393383..97219175 [GRCh37]
Chr10:10q23.33-24.1
likely pathogenic
GRCh37/hg19 10q23.31-24.1(chr10:92667881-98970384)x1 copy number loss See cases [RCV000447362] Chr10:92667881..98970384 [GRCh37]
Chr10:10q23.31-24.1
pathogenic
GRCh37/hg19 10q23.1-25.1(chr10:85557432-105804295)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000431909] Chr10:85557432..105804295 [GRCh37]
Chr10:10q23.1-25.1
pathogenic|drug response
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10q23.32-26.3(chr10:93283493-135427143)x3 copy number gain See cases [RCV000510972] Chr10:93283493..135427143 [GRCh37]
Chr10:10q23.32-26.3
pathogenic
NM_207321.3(ACSM6):c.468G>T (p.Met156Ile) single nucleotide variant Inborn genetic diseases [RCV003290998] Chr10:95207272 [GRCh38]
Chr10:96967029 [GRCh37]
Chr10:10q23.33
uncertain significance
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3
drug response
GRCh37/hg19 10q23.32-24.2(chr10:93908171-101809723)x1 copy number loss See cases [RCV000512315] Chr10:93908171..101809723 [GRCh37]
Chr10:10q23.32-24.2
pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:94346520-135427143)x3 copy number gain not provided [RCV000683291] Chr10:94346520..135427143 [GRCh37]
Chr10:10q23.33-26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10q23.33-24.1(chr10:96711444-97306336)x3 copy number gain not provided [RCV000849461] Chr10:96711444..97306336 [GRCh37]
Chr10:10q23.33-24.1
uncertain significance
GRCh37/hg19 10q23.33-24.1(chr10:96140621-97222801)x3 copy number gain not provided [RCV001258459] Chr10:96140621..97222801 [GRCh37]
Chr10:10q23.33-24.1
uncertain significance
GRCh37/hg19 10q23.33-24.1(chr10:96136737-97224160)x3 copy number gain not provided [RCV001829229] Chr10:96136737..97224160 [GRCh37]
Chr10:10q23.33-24.1
uncertain significance
GRCh37/hg19 10q23.31-24.1(chr10:92667881-98970384) copy number loss not specified [RCV002052882] Chr10:92667881..98970384 [GRCh37]
Chr10:10q23.31-24.1
pathogenic
NM_207321.3(ACSM6):c.1231C>T (p.Pro411Ser) single nucleotide variant Inborn genetic diseases [RCV003261412] Chr10:95225320 [GRCh38]
Chr10:96985077 [GRCh37]
Chr10:10q23.33
uncertain significance
GRCh37/hg19 10q23.33-24.1(chr10:96155285-97224160)x3 copy number gain not provided [RCV002474676] Chr10:96155285..97224160 [GRCh37]
Chr10:10q23.33-24.1
uncertain significance
NM_207321.3(ACSM6):c.212A>G (p.Tyr71Cys) single nucleotide variant Inborn genetic diseases [RCV002901642] Chr10:95202004 [GRCh38]
Chr10:96961761 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.1082A>G (p.Lys361Arg) single nucleotide variant Inborn genetic diseases [RCV002778595] Chr10:95214938 [GRCh38]
Chr10:96974695 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.59C>G (p.Ala20Gly) single nucleotide variant Inborn genetic diseases [RCV002859287] Chr10:95194544 [GRCh38]
Chr10:96954301 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.800G>A (p.Gly267Asp) single nucleotide variant Inborn genetic diseases [RCV002837308] Chr10:95211922 [GRCh38]
Chr10:96971679 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.1234G>C (p.Gly412Arg) single nucleotide variant Inborn genetic diseases [RCV002845104] Chr10:95225323 [GRCh38]
Chr10:96985080 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.887C>T (p.Thr296Ile) single nucleotide variant Inborn genetic diseases [RCV002950182] Chr10:95212009 [GRCh38]
Chr10:96971766 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.967G>C (p.Glu323Gln) single nucleotide variant Inborn genetic diseases [RCV002910817] Chr10:95212912 [GRCh38]
Chr10:96972669 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.224G>C (p.Trp75Ser) single nucleotide variant Inborn genetic diseases [RCV002783517] Chr10:95202016 [GRCh38]
Chr10:96961773 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.526G>A (p.Val176Met) single nucleotide variant Inborn genetic diseases [RCV002964805] Chr10:95207330 [GRCh38]
Chr10:96967087 [GRCh37]
Chr10:10q23.33
likely benign
NM_207321.3(ACSM6):c.1121G>A (p.Gly374Asp) single nucleotide variant Inborn genetic diseases [RCV003008550] Chr10:95219892 [GRCh38]
Chr10:96979649 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.1112C>T (p.Thr371Met) single nucleotide variant Inborn genetic diseases [RCV002897340] Chr10:95214968 [GRCh38]
Chr10:96974725 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.217G>C (p.Ala73Pro) single nucleotide variant Inborn genetic diseases [RCV002879108] Chr10:95202009 [GRCh38]
Chr10:96961766 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.1193T>C (p.Ile398Thr) single nucleotide variant Inborn genetic diseases [RCV002722670] Chr10:95219964 [GRCh38]
Chr10:96979721 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.1423G>A (p.Ala475Thr) single nucleotide variant Inborn genetic diseases [RCV003176237] Chr10:95228764 [GRCh38]
Chr10:96988521 [GRCh37]
Chr10:10q23.33
uncertain significance
GRCh37/hg19 10q23.32-24.1(chr10:93281410-97596360)x1 copy number loss See cases [RCV003159569] Chr10:93281410..97596360 [GRCh37]
Chr10:10q23.32-24.1
pathogenic
NM_207321.3(ACSM6):c.767A>T (p.Asp256Val) single nucleotide variant Inborn genetic diseases [RCV003213110] Chr10:95211889 [GRCh38]
Chr10:96971646 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.766G>T (p.Asp256Tyr) single nucleotide variant Inborn genetic diseases [RCV003213109] Chr10:95211888 [GRCh38]
Chr10:96971645 [GRCh37]
Chr10:10q23.33
uncertain significance
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3
pathogenic
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3
pathogenic
NM_207321.3(ACSM6):c.1259G>A (p.Arg420His) single nucleotide variant Inborn genetic diseases [RCV003356731] Chr10:95225348 [GRCh38]
Chr10:96985105 [GRCh37]
Chr10:10q23.33
uncertain significance
NM_207321.3(ACSM6):c.1175A>G (p.Lys392Arg) single nucleotide variant Inborn genetic diseases [RCV003386616] Chr10:95219946 [GRCh38]
Chr10:96979703 [GRCh37]
Chr10:10q23.33
uncertain significance
GRCh37/hg19 10q23.33-24.1(chr10:96760412-97021792)x3 copy number gain not provided [RCV003484811] Chr10:96760412..97021792 [GRCh37]
Chr10:10q23.33-24.1
uncertain significance
GRCh37/hg19 10q11.21-24.2(chr10:42709645-100834951)x3 copy number gain not provided [RCV003484798] Chr10:42709645..100834951 [GRCh37]
Chr10:10q11.21-24.2
pathogenic
GRCh37/hg19 10q23.33-24.1(chr10:96298410-97426086)x3 copy number gain not provided [RCV003484810] Chr10:96298410..97426086 [GRCh37]
Chr10:10q23.33-24.1
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1601
Count of miRNA genes:634
Interacting mature miRNAs:693
Transcripts:ENST00000327739, ENST00000341686, ENST00000394005, ENST00000404473, ENST00000430183
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
G59656  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371096,970,262 - 96,970,412UniSTSGRCh37
Build 361096,960,252 - 96,960,402RGDNCBI36
Celera1090,711,417 - 90,711,567RGD
Cytogenetic Map10q23.33UniSTS
HuRef1090,597,396 - 90,597,546UniSTS
TNG Radiation Hybrid Map146681.0UniSTS
G65756  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371096,977,508 - 96,977,787UniSTSGRCh37
Build 361096,967,498 - 96,967,777RGDNCBI36
Celera1090,718,670 - 90,718,949RGD
Cytogenetic Map10q23.33UniSTS
HuRef1090,604,649 - 90,604,928UniSTS
G54703  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371096,970,246 - 96,970,432UniSTSGRCh37
Celera1090,711,401 - 90,711,587UniSTS
Cytogenetic Map10q23.33UniSTS
HuRef1090,597,380 - 90,597,566UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 1 1 25 1 2
Low 240 18 465 5 68 4 705 17 30 47 329 464 1 90 305
Below cutoff 1540 1764 1052 415 905 275 2615 1323 2425 221 738 822 149 1 985 1668 1

Sequence


RefSeq Acc Id: ENST00000327739   ⟹   ENSP00000328491
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1095,194,200 - 95,226,405 (+)Ensembl
RefSeq Acc Id: ENST00000341686   ⟹   ENSP00000340296
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1095,194,200 - 95,228,928 (+)Ensembl
RefSeq Acc Id: ENST00000394005   ⟹   ENSP00000377573
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1095,194,238 - 95,228,929 (+)Ensembl
RefSeq Acc Id: ENST00000404473   ⟹   ENSP00000384922
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1095,194,477 - 95,225,335 (+)Ensembl
RefSeq Acc Id: NM_207321   ⟹   NP_997204
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381095,194,238 - 95,228,929 (+)NCBI
GRCh371096,953,957 - 96,988,686 (+)RGD
Build 361096,943,947 - 96,976,152 (+)NCBI Archive
Celera1090,695,101 - 90,729,842 (+)RGD
HuRef1090,581,065 - 90,615,820 (+)ENTREZGENE
CHM1_11097,235,716 - 97,270,449 (+)NCBI
T2T-CHM13v2.01096,073,367 - 96,108,083 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047424638   ⟹   XP_047280594
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381095,194,238 - 95,225,652 (+)NCBI
RefSeq Acc Id: XM_047424639   ⟹   XP_047280595
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381095,194,238 - 95,225,652 (+)NCBI
RefSeq Acc Id: XM_054364868   ⟹   XP_054220843
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01096,073,367 - 96,104,809 (+)NCBI
RefSeq Acc Id: XM_054364869   ⟹   XP_054220844
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01096,073,280 - 96,104,809 (+)NCBI
RefSeq Acc Id: NP_997204   ⟸   NM_207321
- Peptide Label: precursor
- UniProtKB: Q5VZX2 (UniProtKB/Swiss-Prot),   A4IF38 (UniProtKB/Swiss-Prot),   A4FU95 (UniProtKB/Swiss-Prot),   Q6ZTX1 (UniProtKB/Swiss-Prot),   Q6P461 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000384922   ⟸   ENST00000404473
RefSeq Acc Id: ENSP00000328491   ⟸   ENST00000327739
RefSeq Acc Id: ENSP00000377573   ⟸   ENST00000394005
RefSeq Acc Id: ENSP00000340296   ⟸   ENST00000341686
RefSeq Acc Id: XP_047280595   ⟸   XM_047424639
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047280594   ⟸   XM_047424638
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054220844   ⟸   XM_054364869
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054220843   ⟸   XM_054364868
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P461-F1-model_v2 AlphaFold Q6P461 1-480 view protein structure

Promoters
RGD ID:7218245
Promoter ID:EPDNEW_H14868
Type:initiation region
Name:ACSM6_1
Description:acyl-CoA synthetase medium-chain family member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381095,194,238 - 95,194,298EPDNEW

Additional Information

Database Acc Id Source(s)
COSMIC ACSM6 COSMIC
Ensembl Genes ENSG00000173124 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000327739.7 UniProtKB/TrEMBL
  ENST00000394005 ENTREZGENE
  ENST00000394005.4 UniProtKB/Swiss-Prot
  ENST00000404473.6 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12780 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000173124 GTEx
HGNC ID HGNC:31665 ENTREZGENE
Human Proteome Map ACSM6 Human Proteome Map
InterPro AMP-dep_Synth/Lig UniProtKB/Swiss-Prot
  AMP-dep_Synthh-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:142827 UniProtKB/Swiss-Prot
NCBI Gene 142827 ENTREZGENE
PANTHER ACYL-COENZYME A SYNTHETASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACYL-COENZYME A SYNTHETASE ACSM6, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/Swiss-Prot
PharmGKB PA134905303 PharmGKB
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A4FU95 ENTREZGENE
  A4IF38 ENTREZGENE
  ACSM6_HUMAN UniProtKB/Swiss-Prot
  H7BXS6_HUMAN UniProtKB/TrEMBL
  H7BYZ2_HUMAN UniProtKB/TrEMBL
  Q5VZX2 ENTREZGENE
  Q6P461 ENTREZGENE
  Q6ZTX1 ENTREZGENE
UniProt Secondary A4FU95 UniProtKB/Swiss-Prot
  A4IF38 UniProtKB/Swiss-Prot
  Q5VZX2 UniProtKB/Swiss-Prot
  Q6ZTX1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-20 ACSM6  acyl-CoA synthetase medium chain family member 6    acyl-CoA synthetase medium-chain family member 6  Symbol and/or name change 5135510 APPROVED
2014-06-04 ACSM6  acyl-CoA synthetase medium-chain family member 6  C10orf129  chromosome 10 open reading frame 129  Symbol and/or name change 5135510 APPROVED