Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | OR2T4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Endosulfan results in increased expression of OR2T4 mRNA] | CTD | PMID:26159488 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of OR2T47D mRNA | CTD | PMID:21346803 | aflatoxin B1 | decreases methylation | ISO | OR2T4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of OR2T4 gene | CTD | PMID:27153756 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of OR2T4 mRNA and bisphenol A results in decreased expression of OR2T47D mRNA | CTD | PMID:25181051 | endosulfan | multiple interactions | ISO | OR2T4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Endosulfan results in increased expression of OR2T4 mRNA] | CTD | PMID:26159488 | endosulfan | increases expression | ISO | OR2T4 (Homo sapiens) | 6480464 | Endosulfan results in increased expression of OR2T4 mRNA | CTD | PMID:26159488 | hydrogen peroxide | decreases expression | ISO | OR2T4 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of OR2T4 mRNA | CTD | PMID:34581912 | sulforaphane | decreases expression | ISO | OR2T4 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of OR2T4 mRNA | CTD | PMID:26833863 | valproic acid | decreases methylation | ISO | OR2T4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of OR2T4 gene | CTD | PMID:29154799 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Genome sequence of the Brown Norway rat yields insights into mammalian evolution. | Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521. |
| 3. | GOA pipeline | RGD automated data pipeline |
| 4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Genomics
Comparative Map Data
| Or2t47d (Rattus norvegicus - Norway rat) |
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| OR2T4 (Homo sapiens - human) |
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| Or2t46 (Mus musculus - house mouse) |
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| LOC129392907 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| LOC110259735 (Sus scrofa - pig) |
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Variants
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Variants in Or2t47d
3 total Variants 
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