Or14j5e (olfactory receptor family 14 subfamily J member 5E) - Rat Genome Database

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Pathways
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Gene: Or14j5e (olfactory receptor family 14 subfamily J member 5E) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or14j5e
Name: olfactory receptor family 14 subfamily J member 5E
RGD ID: 1333186
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane; INTERACTS WITH C60 fullerene; cadmium dichloride; Cuprizon.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC100910382; olfactory receptor 14J1-like; olfactory receptor 1688; olfactory receptor gene Olr1688; olfactory receptor Olr1688; Olr1688; ratchr20-540075-541079_ORF
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820598,816 - 599,820 (+)NCBIGRCr8
mRatBN7.220593,545 - 594,549 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20589,265 - 599,909 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx20608,603 - 609,607 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.020612,071 - 613,075 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020527,333 - 528,337 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.020915,079 - 916,083 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl20915,079 - 916,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl20734,642 - 735,646 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.020900,113 - 901,117 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.420540,075 - 541,079 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.120540,074 - 541,079 (+)NCBI
Celera201,375,546 - 1,376,550 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or14j5e
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:9
Interacting mature miRNAs:10
Transcripts:ENSRNOT00000073543, ENSRNOT00000074181
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000073543   ⟹   ENSRNOP00000067247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl20734,642 - 735,646 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000074181   ⟹   ENSRNOP00000063954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl20915,079 - 916,083 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110988   ⟹   ENSRNOP00000084399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20589,265 - 599,909 (+)Ensembl
RefSeq Acc Id: NM_001000275   ⟹   NP_001000275
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr820598,816 - 599,820 (+)NCBI
mRatBN7.220593,545 - 594,549 (+)NCBI
Rnor_6.020915,079 - 916,083 (+)NCBI
Rnor_5.020900,113 - 901,117 (+)NCBI
RGSC_v3.420540,075 - 541,079 (+)RGD
Celera201,375,546 - 1,376,550 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000275 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000084399
  ENSRNOP00000084399.1
Reference Protein Sequences
RefSeq Acc Id: NP_001000275   ⟸   NM_001000275
- UniProtKB: M0RCD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063954   ⟸   ENSRNOT00000074181
RefSeq Acc Id: ENSRNOP00000067247   ⟸   ENSRNOT00000073543
RefSeq Acc Id: ENSRNOP00000084399   ⟸   ENSRNOT00000110988
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RCD3-F1-model_v2 AlphaFold M0RCD3 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333186 AgrOrtholog
BioCyc Gene G2FUF-5071 BioCyc
Ensembl Genes ENSRNOG00000046733 Ensembl
  ENSRNOG00000050612 Ensembl
  ENSRNOG00000065073 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000110988 ENTREZGENE
  ENSRNOT00000110988.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:294164 UniProtKB/TrEMBL
NCBI Gene 294164 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or14j5e PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046733 RatGTEx
  ENSRNOG00000050612 RatGTEx
  ENSRNOG00000065073 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt M0RCD3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or14j5e  olfactory receptor family 14 subfamily J member 5E  Olr1688  olfactory receptor 1688  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr1688  olfactory receptor 1688  LOC100910382  olfactory receptor 14J1-like  Data merged from RGD:6499045 737654 PROVISIONAL
2012-07-05 LOC100910382  olfactory receptor 14J1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1688  olfactory receptor 1688   Olr1688_predicted  olfactory receptor 1688 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1688_predicted  olfactory receptor 1688 (predicted)      Symbol and Name status set to approved 70820 APPROVED