Or12d14c (olfactory receptor family 12 subfamily D member 14C) - Rat Genome Database

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Gene: Or12d14c (olfactory receptor family 12 subfamily D member 14C) Rattus norvegicus
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Symbol: Or12d14c
Name: olfactory receptor family 12 subfamily D member 14C
RGD ID: 1333138
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR12D2 (olfactory receptor family 12 subfamily D member 2); INTERACTS WITH cadmium dichloride; trichloroethene; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1738; olfactory receptor gene Olr1738; Olr1738; Or12
RGD Orthologs
Human
Mouse
Bonobo
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,301,891 - 1,302,781 (+)NCBIGRCr8
mRatBN7.2201,296,642 - 1,297,532 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,296,470 - 1,297,620 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,349,844 - 1,350,734 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,353,330 - 1,354,220 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,294,865 - 1,295,755 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,787,346 - 1,788,236 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,787,174 - 1,788,324 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,831,522 - 3,832,412 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,387,403 - 1,388,293 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera202,010,138 - 2,011,028 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, etal., Genome Res 2004 Apr;14(4):631-9.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or12d14c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,301,891 - 1,302,781 (+)NCBIGRCr8
mRatBN7.2201,296,642 - 1,297,532 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,296,470 - 1,297,620 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,349,844 - 1,350,734 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,353,330 - 1,354,220 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,294,865 - 1,295,755 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,787,346 - 1,788,236 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,787,174 - 1,788,324 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,831,522 - 3,832,412 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,387,403 - 1,388,293 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera202,010,138 - 2,011,028 (+)NCBICelera
Cytogenetic Map20p12NCBI
OR12D2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,395,631 - 29,398,008 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,395,631 - 29,398,008 (+)EnsemblGRCh38hg38GRCh38
GRCh37629,363,408 - 29,365,785 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,472,456 - 29,473,379 (+)NCBINCBI36Build 36hg18NCBI36
Build 34629,472,455 - 29,473,379NCBI
Celera630,970,469 - 30,971,501 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,171,566 - 29,172,598 (+)NCBIHuRef
CHM1_1629,366,381 - 29,367,413 (+)NCBICHM1_1
T2T-CHM13v2.0629,270,421 - 29,272,655 (+)NCBIT2T-CHM13v2.0
Or12d2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,624,302 - 37,625,328 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,622,686 - 37,627,945 (-)EnsemblGRCm39 Ensembl
GRCm381737,313,411 - 37,314,437 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,311,795 - 37,317,054 (-)EnsemblGRCm38mm10GRCm38
MGSCv371737,450,356 - 37,451,382 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361736,921,509 - 36,922,435 (-)NCBIMGSCv36mm8
Celera1740,757,004 - 40,758,028 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
LOC100971665
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,028,947 - 44,031,197 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,993,312 - 39,995,562 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,215,484 - 29,216,711 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,873,579 - 29,875,145 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC101959288
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,250,360 - 32,251,286 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367231,340,597 - 1,341,523 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110255232
(Sus scrofa - pig)		 No map positions available.

Variants

.
Variants in Or12d14c
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:52
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000041883
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1 14 17 10 1 4 9
Below cutoff 1 4 6 4 2 4 2 2 1 7 3 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000041883   ⟹   ENSRNOP00000040084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,787,310 - 1,788,236 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072824   ⟹   ENSRNOP00000067856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,296,470 - 1,297,620 (+)Ensembl
Rnor_6.0 Ensembl201,787,174 - 1,788,324 (+)Ensembl
RefSeq Acc Id: NM_001006599   ⟹   NP_001006599
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,301,891 - 1,302,781 (+)NCBI
mRatBN7.2201,296,642 - 1,297,532 (+)NCBI
Rnor_6.0201,787,346 - 1,788,236 (+)NCBI
Rnor_5.0203,831,522 - 3,832,412 (+)NCBI
RGSC_v3.4201,387,403 - 1,388,293 (+)RGD
Celera202,010,138 - 2,011,028 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001006599 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040084.2
  ENSRNOP00000067856
  ENSRNOP00000067856.2
Reference Protein Sequences
RefSeq Acc Id: NP_001006599   ⟸   NM_001006599
- UniProtKB: M0RDZ2 (UniProtKB/TrEMBL),   F1LV77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067856   ⟸   ENSRNOT00000072824
RefSeq Acc Id: ENSRNOP00000040084   ⟸   ENSRNOT00000041883
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LV77-F1-model_v2 AlphaFold F1LV77 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333138 AgrOrtholog
BioCyc Gene G2FUF-5005 BioCyc
Ensembl Genes ENSRNOG00000029883 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000065286 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041883.2 UniProtKB/TrEMBL
  ENSRNOT00000072824 ENTREZGENE
  ENSRNOT00000072824.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:406039 UniProtKB/TrEMBL
NCBI Gene 406039 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or12d14c PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029883 RatGTEx
  ENSRNOG00000065286 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt F1LV77 ENTREZGENE, UniProtKB/TrEMBL
  M0RDZ2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or12d14c  olfactory receptor family 12 subfamily D member 14C  Olr1738  olfactory receptor 1738  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1738  olfactory receptor 1738   Olr1738_predicted  olfactory receptor 1738 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1738_predicted  olfactory receptor 1738 (predicted)      Symbol and Name status set to approved 70820 APPROVED