Or8h7b (olfactory receptor family 8 subfamily H member 7B) - Rat Genome Database

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Gene: Or8h7b (olfactory receptor family 8 subfamily H member 7B) Rattus norvegicus
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Symbol: Or8h7b (Ensembl: Olr522)
Name: olfactory receptor family 8 subfamily H member 7B (Ensembl:olfactory receptor 522)
RGD ID: 1333046
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Orthologous to human OR8H2 (olfactory receptor family 8 subfamily H member 2); INTERACTS WITH vinclozolin; 2-hydroxypropanoic acid (ortholog); 2-palmitoylglycerol (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 522; olfactory receptor gene Olr522; olfactory receptor Olr522; Olr522; ratchr3-70010454-70009507_ORF
RGD Orthologs
Human
Mouse
Bonobo
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8392,297,102 - 92,298,049 (-)NCBIGRCr8
UTH_Rnor_SHR_Utx375,285,852 - 75,286,799 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0383,884,394 - 83,885,341 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0381,663,824 - 81,664,771 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0374,255,120 - 74,256,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl374,255,120 - 74,256,067 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0380,905,288 - 80,906,235 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4370,113,135 - 70,114,082 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1370,009,506 - 70,010,454 (-)NCBI
Celera371,191,227 - 71,192,174 (-)NCBICelera
Cytogenetic Map3q24NCBI


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or8h7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8392,297,102 - 92,298,049 (-)NCBIGRCr8
UTH_Rnor_SHR_Utx375,285,852 - 75,286,799 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0383,884,394 - 83,885,341 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0381,663,824 - 81,664,771 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0374,255,120 - 74,256,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl374,255,120 - 74,256,067 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0380,905,288 - 80,906,235 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4370,113,135 - 70,114,082 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1370,009,506 - 70,010,454 (-)NCBI
Celera371,191,227 - 71,192,174 (-)NCBICelera
Cytogenetic Map3q24NCBI
OR8H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,103,687 - 56,107,658 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,103,687 - 56,107,658 (+)EnsemblGRCh38hg38GRCh38
GRCh371155,871,163 - 55,875,134 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361155,629,095 - 55,630,033 (+)NCBINCBI36Build 36hg18NCBI36
Build 341155,629,094 - 55,630,033NCBI
Celera1153,212,689 - 53,213,627 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1152,201,516 - 52,202,454 (+)NCBIHuRef
CHM1_11155,738,044 - 55,738,982 (+)NCBICHM1_1
T2T-CHM13v2.01156,042,036 - 56,046,005 (+)NCBIT2T-CHM13v2.0
Or8h10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39286,808,173 - 86,809,138 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl286,806,373 - 86,810,298 (-)EnsemblGRCm39 Ensembl
GRCm38286,977,829 - 86,978,794 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl286,976,029 - 86,979,954 (-)EnsemblGRCm38mm10GRCm38
MGSCv37286,817,986 - 86,818,951 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36286,778,668 - 86,779,633 (-)NCBIMGSCv36mm8
Celera288,569,128 - 88,570,093 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.86NCBI
LOC100972794
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2957,264,642 - 57,268,623 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11158,280,164 - 58,284,146 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01151,349,105 - 51,350,213 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:13
Count of miRNA genes:12
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000047747
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

respiratory system
High
Medium
Low
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000047747   ⟹   ENSRNOP00000041464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl374,255,120 - 74,256,067 (-)Ensembl
RefSeq Acc Id: NM_001000562   ⟹   NP_001000562
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8392,297,102 - 92,298,049 (-)NCBI
Rnor_6.0374,255,120 - 74,256,067 (-)NCBI
Rnor_5.0380,905,288 - 80,906,235 (-)NCBI
RGSC_v3.4370,113,135 - 70,114,082 (-)RGD
Celera371,191,227 - 71,192,174 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000562 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001000562   ⟸   NM_001000562
- UniProtKB: D3ZLZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041464   ⟸   ENSRNOT00000047747

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLZ1-F1-model_v2 AlphaFold D3ZLZ1 1-315 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333046 AgrOrtholog
Ensembl Genes ENSRNOG00000049234 Ensembl
NCBI Gene 366100 ENTREZGENE
PhenoGen Or8h7b PhenoGen
RatGTEx ENSRNOG00000049234 RatGTEx
UniProt D3ZLZ1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or8h7b  olfactory receptor family 8 subfamily H member 7B  Olr522  olfactory receptor 522  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr522  olfactory receptor 522   Olr522_predicted  olfactory receptor 522 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr522_predicted  olfactory receptor 522 (predicted)      Symbol and Name status set to approved 70820 APPROVED