Or1f21c (olfactory receptor family 1 subfamily F member 21C) - Rat Genome Database

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Gene: Or1f21c (olfactory receptor family 1 subfamily F member 21C) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or1f21c (Ensembl: Or1f21b)
Name: olfactory receptor family 1 subfamily F member 21C (Ensembl:olfactory receptor family 1 subfamily F member 21B)
RGD ID: 1332793
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. Orthologous to human OR1F1 (olfactory receptor family 1 subfamily F member 1); INTERACTS WITH copper atom; copper(0).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1525; olfactory receptor gene Olr1525; olfactory receptor Olr1525; Olr1525; ratchr10_random-311207-310245_ORF
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81012,409,643 - 12,410,605 (-)NCBIGRCr8
mRatBN7.21011,903,285 - 11,904,247 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1011,899,986 - 11,904,247 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1011,969,158 - 11,973,419 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01012,283,775 - 12,284,736 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,311,730 - 12,312,692 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,283,775 - 12,284,736 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,118,157 - 12,125,254 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1010,842,159 - 10,843,121 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
copper atom  (EXP)
copper(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:77
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000073059
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000081865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1012,283,775 - 12,284,736 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101770   ⟹   ENSRNOP00000097608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1011,969,158 - 11,973,419 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107258   ⟹   ENSRNOP00000087310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1011,899,986 - 11,904,247 (-)Ensembl
RefSeq Acc Id: NM_001000529   ⟹   NP_001000529
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81012,409,643 - 12,410,605 (-)NCBI
mRatBN7.21011,903,285 - 11,904,247 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001000529 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000087310.1
  ENSRNOP00000097608.1
Reference Protein Sequences
RefSeq Acc Id: NP_001000529   ⟸   NM_001000529
- UniProtKB: A0A8I6GFV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000097608   ⟸   ENSRNOT00000101770
RefSeq Acc Id: ENSRNOP00000087310   ⟸   ENSRNOT00000107258
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R4C2-F1-model_v2 AlphaFold M0R4C2 1-320 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1332793 AgrOrtholog
BioCyc Gene G2FUF-25981 BioCyc
Ensembl Genes ENSRNOG00000050126 Ensembl
  ENSRNOG00000061166 Ensembl
  ENSRNOG00000066553 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000067870 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000101770.1 UniProtKB/TrEMBL
  ENSRNOT00000107258.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene 363710 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 1J4 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1f21c PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050126 RatGTEx
  ENSRNOG00000061166 RatGTEx
  ENSRNOG00000066553 RatGTEx
  ENSRNOG00000067870 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6GFV7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or1f21c  olfactory receptor family 1 subfamily F member 21C  Olr1525  olfactory receptor 1525  Symbol and Name Changed 1299863 APPROVED
2022-06-02 Olr1525  olfactory receptor 1525  Olr1525  olfactory receptor 1525  Data merged from RGD:149736416 737654 PROVISIONAL
2021-08-09 Olr1525  olfactory receptor 1525      Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 Olr1525  olfactory receptor 1525   Olr1525_predicted  olfactory receptor 1525 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1525_predicted  olfactory receptor 1525 (predicted)      Symbol and Name status set to approved 70820 APPROVED