Or1f19 (olfactory receptor family 1 subfamily F member 19) - Rat Genome Database

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Gene: Or1f19 (olfactory receptor family 1 subfamily F member 19) Rattus norvegicus
Analyze
Symbol: Or1f19
Name: olfactory receptor family 1 subfamily F member 19
RGD ID: 1332671
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. Orthologous to human OR1F1 (olfactory receptor family 1 subfamily F member 1) and OR1F2P (olfactory receptor family 1 subfamily F member 2 pseudogene); INTERACTS WITH benzo[a]pyrene (ortholog); crocidolite asbestos (ortholog); valproic acid (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1373; olfactory receptor gene Olr1373; olfactory receptor Olr1373; Olr1373
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81012,767,753 - 12,768,694 (+)NCBIGRCr8
mRatBN7.21012,263,109 - 12,264,050 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,261,803 - 12,264,965 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1016,952,691 - 16,953,632 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,441,501 - 16,442,442 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01011,989,472 - 11,990,413 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01012,602,388 - 12,603,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,602,388 - 12,603,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,426,322 - 12,427,263 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41012,479,223 - 12,480,164 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11012,479,222 - 12,480,164 (+)NCBI
Celera1011,988,212 - 11,989,153 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or1f19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81012,767,753 - 12,768,694 (+)NCBIGRCr8
mRatBN7.21012,263,109 - 12,264,050 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,261,803 - 12,264,965 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1016,952,691 - 16,953,632 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,441,501 - 16,442,442 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01011,989,472 - 11,990,413 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01012,602,388 - 12,603,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,602,388 - 12,603,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,426,322 - 12,427,263 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41012,479,223 - 12,480,164 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11012,479,222 - 12,480,164 (+)NCBI
Celera1011,988,212 - 11,989,153 (+)NCBICelera
Cytogenetic Map10q12NCBI
OR1F2P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,215,562 - 3,216,546 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,215,611 - 3,216,543 (+)EnsemblGRCh38hg38GRCh38
GRCh37163,265,562 - 3,266,546 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,205,563 - 3,206,547 (+)NCBINCBI36Build 36hg18NCBI36
Build 34163,205,551 - 3,206,550NCBI
Celera163,471,235 - 3,472,219 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef163,235,410 - 3,236,394 (+)NCBIHuRef
CHM1_1163,265,510 - 3,266,494 (+)NCBICHM1_1
T2T-CHM13v2.0163,242,672 - 3,243,656 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in Or1f19
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000060989
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system integumental system musculoskeletal system nervous system appendage
High
Medium
Low
Below cutoff 1 1 1 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000060989   ⟹   ENSRNOP00000057708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1012,261,803 - 12,264,965 (+)Ensembl
Rnor_6.0 Ensembl1012,602,388 - 12,603,329 (+)Ensembl
RefSeq Acc Id: NM_214830   ⟹   NP_999995
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81012,767,753 - 12,768,694 (+)NCBI
mRatBN7.21012,263,109 - 12,264,050 (+)NCBI
Rnor_6.01012,602,388 - 12,603,329 (+)NCBI
Rnor_5.01012,426,322 - 12,427,263 (+)NCBI
RGSC_v3.41012,479,223 - 12,480,164 (+)RGD
Celera1011,988,212 - 11,989,153 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_999995 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057708
  ENSRNOP00000057708.2
Reference Protein Sequences
RefSeq Acc Id: NP_999995   ⟸   NM_214830
- UniProtKB: D4A222 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000057708   ⟸   ENSRNOT00000060989
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A222-F1-model_v2 AlphaFold D4A222 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1332671 AgrOrtholog
BioCyc Gene G2FUF-25964 BioCyc
Ensembl Genes ENSRNOG00000039760 Ensembl
  ENSRNOG00000065251 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060989 ENTREZGENE
  ENSRNOT00000060989.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:287090 UniProtKB/TrEMBL
NCBI Gene 287090 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 1F1-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1f19 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039760 RatGTEx
  ENSRNOG00000065251 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D4A222 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or1f19  olfactory receptor family 1 subfamily F member 19  Olr1373  olfactory receptor 1373  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1373  olfactory receptor 1373   Olr1373_predicted  olfactory receptor 1373 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1373_predicted  olfactory receptor 1373 (predicted)      Symbol and Name status set to approved 70820 APPROVED