Or1o11b (olfactory receptor family 1 subfamily O member 11B) - Rat Genome Database

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Pathways
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Gene: Or1o11b (olfactory receptor family 1 subfamily O member 11B) Rattus norvegicus
Analyze
Symbol: Or1o11b
Name: olfactory receptor family 1 subfamily O member 11B
RGD ID: 1332651
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane; INTERACTS WITH cadmium dichloride; copper atom; copper(0).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1726; olfactory receptor gene Olr1726; olfactory receptor Olr1726; Olr1726
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,117,064 - 1,117,993 (-)NCBIGRCr8
mRatBN7.2201,111,816 - 1,112,745 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,111,816 - 1,112,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,146,741 - 1,147,670 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,150,223 - 1,151,152 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.0201,577,657 - 1,578,590 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,577,656 - 1,578,595 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,622,612 - 3,623,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,199,859 - 1,200,788 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,199,858 - 1,200,788 (-)NCBI
Celera201,850,716 - 1,851,645 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or1o11b
25 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:82
Count of miRNA genes:54
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000048085, ENSRNOT00000074574
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

nervous system
High
Medium
Low
Below cutoff 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000079038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,577,656 - 1,578,595 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105836   ⟹   ENSRNOP00000087962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,111,816 - 1,112,745 (-)Ensembl
RefSeq Acc Id: NM_001000896   ⟹   NP_001000896
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,117,064 - 1,117,993 (-)NCBI
mRatBN7.2201,111,816 - 1,112,745 (-)NCBI
Rnor_6.0201,577,657 - 1,578,590 (-)NCBI
Rnor_5.0203,622,612 - 3,623,545 (-)NCBI
RGSC_v3.4201,199,859 - 1,200,788 (-)RGD
Celera201,850,716 - 1,851,645 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000896 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000087962
  ENSRNOP00000087962.1
Reference Protein Sequences
RefSeq Acc Id: NP_001000896   ⟸   NM_001000896
- UniProtKB: A0A8I6A8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000087962   ⟸   ENSRNOT00000105836
Protein Domains
G-protein coupled receptors family 1 profile

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-5023 BioCyc
Ensembl Genes ENSRNOG00000053091 Ensembl
  ENSRNOG00000062631 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000105836 ENTREZGENE
  ENSRNOT00000105836.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405204 UniProtKB/TrEMBL
NCBI Gene 405204 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1o11b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053091 RatGTEx
  ENSRNOG00000062631 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6A8T3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or1o11b  olfactory receptor family 1 subfamily O member 11B  Olr1726  olfactory receptor 1726  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1726  olfactory receptor 1726   Olr1726_predicted  olfactory receptor 1726 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1726_predicted  olfactory receptor 1726 (predicted)      Symbol and Name status set to approved 70820 APPROVED