Nexn (nexilin) - Rat Genome Database

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Gene: Nexn (nexilin) Mus musculus
Analyze
Symbol: Nexn
Name: nexilin
RGD ID: 1331922
MGI Page MGI
Description: Predicted to enable actin filament binding activity and cell-cell adhesion mediator activity. Predicted to be a structural constituent of muscle. Acts upstream of or within response to bacterium. Predicted to be located in actin cytoskeleton and cell-substrate junction. Predicted to be active in several cellular components, including Z disc; axon; and focal adhesion. Is expressed in diaphragm; gut; head mesenchyme; heart; and vertebral axis musculature. Used to study dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Orthologous to human NEXN (nexilin F-actin binding protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110046H09Rik; AA553326; F-actin binding protein; F-actin-binding protein; nelin; nexilin alpha; nexilin beta; nexilin gamma; nF actin binding protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393151,942,619 - 151,972,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3151,942,619 - 151,971,987 (-)EnsemblGRCm39 Ensembl
GRCm383152,236,982 - 152,266,350 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3152,236,982 - 152,266,350 (-)EnsemblGRCm38mm10GRCm38
MGSCv373151,899,946 - 151,929,284 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363152,174,368 - 152,216,670 (-)NCBIMGSCv36mm8
Celera3158,714,841 - 158,744,187 (-)NCBICelera
Cytogenetic Map3H3NCBI
cM Map377.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
ammonium hexachloroplatinate  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bucladesine  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cantharidin  (EXP)
carbamazepine  (ISO)
choline  (EXP)
chrysene  (EXP)
cisplatin  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (ISO)
glycidyl methacrylate  (ISO)
hexadecanoic acid  (ISO)
hexamethylene diisocyanate  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (ISO)
medroxyprogesterone acetate  (ISO)
methyl methanesulfonate  (ISO)
nickel atom  (EXP)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenylmercury acetate  (ISO)
pioglitazone  (EXP)
progesterone  (ISO)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
resorcinol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (EXP)
triadimefon  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP)
valproic acid  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11544199   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:23012479   PMID:24427314   PMID:24457600   PMID:24623780   PMID:24866383   PMID:25826454   PMID:26659360   PMID:26930384   PMID:27171814   PMID:30335684   PMID:30589415  
PMID:30635555   PMID:30982350   PMID:32325033   PMID:32635769   PMID:32814711   PMID:35273083   PMID:36220570  


Genomics

Comparative Map Data
Nexn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393151,942,619 - 151,972,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3151,942,619 - 151,971,987 (-)EnsemblGRCm39 Ensembl
GRCm383152,236,982 - 152,266,350 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3152,236,982 - 152,266,350 (-)EnsemblGRCm38mm10GRCm38
MGSCv373151,899,946 - 151,929,284 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363152,174,368 - 152,216,670 (-)NCBIMGSCv36mm8
Celera3158,714,841 - 158,744,187 (-)NCBICelera
Cytogenetic Map3H3NCBI
cM Map377.07NCBI
NEXN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,888,624 - 77,943,895 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,888,513 - 77,943,895 (+)EnsemblGRCh38hg38GRCh38
GRCh37178,354,309 - 78,409,580 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,126,788 - 78,182,168 (+)NCBINCBI36Build 36hg18NCBI36
Build 34178,095,828 - 78,120,930NCBI
Celera176,593,252 - 76,648,659 (+)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef176,485,827 - 76,541,199 (+)NCBIHuRef
CHM1_1178,470,589 - 78,525,920 (+)NCBICHM1_1
T2T-CHM13v2.0177,727,428 - 77,782,694 (+)NCBIT2T-CHM13v2.0
Nexn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82243,846,736 - 243,878,268 (-)NCBIGRCr8
mRatBN7.22241,186,783 - 241,218,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2241,186,790 - 241,218,342 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2249,001,122 - 249,021,940 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02246,888,139 - 246,908,957 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02241,787,531 - 241,808,345 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02257,452,937 - 257,484,607 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2257,453,347 - 257,484,587 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02276,129,684 - 276,161,434 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42250,762,017 - 250,783,765 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12250,776,623 - 250,798,372 (-)NCBI
Celera2233,122,059 - 233,142,757 (-)NCBICelera
Cytogenetic Map2q45NCBI
Nexn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542315,278,526 - 15,299,659 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542315,278,526 - 15,299,654 (-)NCBIChiLan1.0ChiLan1.0
NEXN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21148,945,882 - 149,003,523 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,104,269 - 77,162,517 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,187,779 - 79,247,161 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,187,779 - 79,244,732 (+)Ensemblpanpan1.1panPan2
NEXN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1668,963,953 - 69,014,874 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl668,964,187 - 69,107,009 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha671,621,447 - 71,672,401 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0669,548,680 - 69,599,798 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl669,549,074 - 69,597,504 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1669,055,004 - 69,106,149 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0669,000,304 - 69,051,252 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0669,486,699 - 69,537,684 (-)NCBIUU_Cfam_GSD_1.0
Nexn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505889,191,107 - 89,217,953 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365714,703,955 - 4,729,018 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365714,704,009 - 4,728,305 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEXN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6135,318,754 - 135,382,882 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16135,315,000 - 135,382,911 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26125,500,984 - 125,502,455 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NEXN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12055,229,093 - 55,286,703 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2055,234,782 - 55,285,755 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603362,227,938 - 62,283,369 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nexn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474219,313,264 - 19,349,394 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474219,313,262 - 19,357,052 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nexn
640 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:116
Interacting mature miRNAs:120
Transcripts:ENSMUST00000046045
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119057332153057456Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119057332153057456Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119318586153318586Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119318586153318586Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3119778857153779044Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3120772078154772078Mouse
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse
1301222Scc7_mcolon tumor susceptibility 7 (mouse)Not determined3143352986156364108Mouse
10045615Hrtfm8_mheart failure modifier 8 (mouse)Not determined3148451045152592311Mouse

Markers in Region
RH125594  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383152,237,018 - 152,237,270UniSTSGRCm38
MGSCv373151,899,982 - 151,900,234UniSTSGRCm37
Celera3158,714,877 - 158,715,129UniSTS
Cytogenetic Map3H3UniSTS
cM Map370.5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001357206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_199465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ179982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ179983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ179984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000046045   ⟹   ENSMUSP00000037120
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,942,619 - 151,971,955 (-)Ensembl
GRCm38.p6 Ensembl3152,236,982 - 152,266,318 (-)Ensembl
RefSeq Acc Id: ENSMUST00000196504   ⟹   ENSMUSP00000143180
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,953,718 - 151,967,172 (-)Ensembl
GRCm38.p6 Ensembl3152,248,081 - 152,261,535 (-)Ensembl
RefSeq Acc Id: ENSMUST00000196529   ⟹   ENSMUSP00000143436
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,943,251 - 151,953,901 (-)Ensembl
GRCm38.p6 Ensembl3152,237,614 - 152,248,264 (-)Ensembl
RefSeq Acc Id: ENSMUST00000196815   ⟹   ENSMUSP00000142573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,953,669 - 151,971,432 (-)Ensembl
GRCm38.p6 Ensembl3152,248,032 - 152,265,795 (-)Ensembl
RefSeq Acc Id: ENSMUST00000197282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,958,154 - 151,971,987 (-)Ensembl
GRCm38.p6 Ensembl3152,252,517 - 152,266,350 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198404
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,953,658 - 151,954,101 (-)Ensembl
GRCm38.p6 Ensembl3152,248,021 - 152,248,464 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198460   ⟹   ENSMUSP00000143573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,943,288 - 151,960,948 (-)Ensembl
GRCm38.p6 Ensembl3152,237,651 - 152,255,311 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198648   ⟹   ENSMUSP00000143294
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,953,700 - 151,969,143 (-)Ensembl
GRCm38.p6 Ensembl3152,248,063 - 152,263,506 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198734
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,948,377 - 151,949,773 (-)Ensembl
GRCm38.p6 Ensembl3152,242,740 - 152,244,136 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198750   ⟹   ENSMUSP00000142574
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,949,649 - 151,961,002 (-)Ensembl
GRCm38.p6 Ensembl3152,244,012 - 152,255,365 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199423   ⟹   ENSMUSP00000142936
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,943,203 - 151,960,948 (-)Ensembl
GRCm38.p6 Ensembl3152,237,566 - 152,255,311 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199470   ⟹   ENSMUSP00000143133
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,942,619 - 151,971,404 (-)Ensembl
GRCm38.p6 Ensembl3152,236,982 - 152,265,767 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199685   ⟹   ENSMUSP00000142569
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,953,820 - 151,968,167 (-)Ensembl
GRCm38.p6 Ensembl3152,248,183 - 152,262,530 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199752
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,958,367 - 151,958,735 (-)Ensembl
GRCm38.p6 Ensembl3152,252,730 - 152,253,098 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199983
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,943,889 - 151,950,462 (-)Ensembl
GRCm38.p6 Ensembl3152,238,252 - 152,244,825 (-)Ensembl
RefSeq Acc Id: ENSMUST00000200589   ⟹   ENSMUSP00000142559
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3151,949,593 - 151,971,405 (-)Ensembl
GRCm38.p6 Ensembl3152,243,956 - 152,265,768 (-)Ensembl
RefSeq Acc Id: NM_001357206   ⟹   NP_001344135
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,619 - 151,971,407 (-)NCBI
GRCm383152,236,982 - 152,265,795 (-)NCBI
Sequence:
RefSeq Acc Id: NM_199465   ⟹   NP_955759
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,619 - 151,971,955 (-)NCBI
GRCm383152,236,982 - 152,266,350 (-)NCBI
MGSCv373151,899,946 - 151,929,284 (-)RGD
Celera3158,714,841 - 158,744,187 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501990   ⟹   XP_006502053
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,970,843 (-)NCBI
GRCm383152,237,056 - 152,265,682 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501991   ⟹   XP_006502054
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,970,316 (-)NCBI
GRCm383152,237,056 - 152,264,902 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501993   ⟹   XP_006502056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,972,000 (-)NCBI
GRCm383152,237,056 - 152,266,235 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501996   ⟹   XP_006502059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,971,774 (-)NCBI
GRCm383152,237,056 - 152,266,164 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501998   ⟹   XP_006502061
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,971,775 (-)NCBI
GRCm383152,237,056 - 152,266,163 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240214   ⟹   XP_011238516
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,970,843 (-)NCBI
GRCm383152,237,056 - 152,265,682 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240216   ⟹   XP_011238518
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,971,773 (-)NCBI
GRCm383152,237,056 - 152,266,163 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252783   ⟹   XP_030108643
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,970,842 (-)NCBI
GRCm383152,237,056 - 152,265,682 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036163268   ⟹   XP_036019161
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393151,942,693 - 151,972,000 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001344135 (Get FASTA)   NCBI Sequence Viewer  
  NP_955759 (Get FASTA)   NCBI Sequence Viewer  
  XP_006502053 (Get FASTA)   NCBI Sequence Viewer  
  XP_006502054 (Get FASTA)   NCBI Sequence Viewer  
  XP_006502056 (Get FASTA)   NCBI Sequence Viewer  
  XP_006502059 (Get FASTA)   NCBI Sequence Viewer  
  XP_006502061 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238516 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238518 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108643 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019161 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH52878 (Get FASTA)   NCBI Sequence Viewer  
  AEM53920 (Get FASTA)   NCBI Sequence Viewer  
  AEM53921 (Get FASTA)   NCBI Sequence Viewer  
  AEM53922 (Get FASTA)   NCBI Sequence Viewer  
  BAE22724 (Get FASTA)   NCBI Sequence Viewer  
  BAE22818 (Get FASTA)   NCBI Sequence Viewer  
  BAE22822 (Get FASTA)   NCBI Sequence Viewer  
  BAE37339 (Get FASTA)   NCBI Sequence Viewer  
  EDL11929 (Get FASTA)   NCBI Sequence Viewer  
  EDL11930 (Get FASTA)   NCBI Sequence Viewer  
  EDL11931 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000037120
  ENSMUSP00000037120.9
  ENSMUSP00000142559.2
  ENSMUSP00000142569.2
  ENSMUSP00000142573.2
  ENSMUSP00000142574.2
  ENSMUSP00000142936
  ENSMUSP00000142936.2
  ENSMUSP00000143133
  ENSMUSP00000143133.2
  ENSMUSP00000143180.2
  ENSMUSP00000143294.2
  ENSMUSP00000143436.2
  ENSMUSP00000143573
  ENSMUSP00000143573.2
GenBank Protein Q7TPW1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_955759   ⟸   NM_199465
- Peptide Label: isoform 2
- UniProtKB: Q3UWU6 (UniProtKB/Swiss-Prot),   Q3UWU2 (UniProtKB/Swiss-Prot),   Q3TQP3 (UniProtKB/Swiss-Prot),   E9QJX5 (UniProtKB/Swiss-Prot),   Q3UX39 (UniProtKB/Swiss-Prot),   Q7TPW1 (UniProtKB/Swiss-Prot),   G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502056   ⟸   XM_006501993
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JEX1 (UniProtKB/TrEMBL),   G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502059   ⟸   XM_006501996
- Peptide Label: isoform X2
- UniProtKB: G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502061   ⟸   XM_006501998
- Peptide Label: isoform X3
- UniProtKB: Q3UWU6 (UniProtKB/Swiss-Prot),   Q3UWU2 (UniProtKB/Swiss-Prot),   Q3TQP3 (UniProtKB/Swiss-Prot),   E9QJX5 (UniProtKB/Swiss-Prot),   Q3UX39 (UniProtKB/Swiss-Prot),   Q7TPW1 (UniProtKB/Swiss-Prot),   G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502053   ⟸   XM_006501990
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JEX1 (UniProtKB/TrEMBL),   G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502054   ⟸   XM_006501991
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JEX1 (UniProtKB/TrEMBL),   G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011238518   ⟸   XM_011240216
- Peptide Label: isoform X4
- UniProtKB: G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011238516   ⟸   XM_011240214
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JEX1 (UniProtKB/TrEMBL),   G4W8R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001344135   ⟸   NM_001357206
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JEX1 (UniProtKB/TrEMBL),   G4W8R2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108643   ⟸   XM_030252783
- Peptide Label: isoform X2
- UniProtKB: G4W8R2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000143294   ⟸   ENSMUST00000198648
RefSeq Acc Id: ENSMUSP00000142574   ⟸   ENSMUST00000198750
RefSeq Acc Id: ENSMUSP00000143573   ⟸   ENSMUST00000198460
RefSeq Acc Id: ENSMUSP00000037120   ⟸   ENSMUST00000046045
RefSeq Acc Id: ENSMUSP00000143133   ⟸   ENSMUST00000199470
RefSeq Acc Id: ENSMUSP00000142936   ⟸   ENSMUST00000199423
RefSeq Acc Id: ENSMUSP00000142569   ⟸   ENSMUST00000199685
RefSeq Acc Id: ENSMUSP00000142573   ⟸   ENSMUST00000196815
RefSeq Acc Id: ENSMUSP00000143436   ⟸   ENSMUST00000196529
RefSeq Acc Id: ENSMUSP00000143180   ⟸   ENSMUST00000196504
RefSeq Acc Id: ENSMUSP00000142559   ⟸   ENSMUST00000200589
RefSeq Acc Id: XP_036019161   ⟸   XM_036163268
- Peptide Label: isoform X2
- UniProtKB: G4W8R2 (UniProtKB/TrEMBL)
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TPW1-F1-model_v2 AlphaFold Q7TPW1 1-607 view protein structure

Promoters
RGD ID:6834147
Promoter ID:MM_KWN:36426
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   MEF_B4
Transcripts:UC008RTC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363151,910,836 - 151,911,687 (-)MPROMDB
RGD ID:6834148
Promoter ID:MM_KWN:36427
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   MEF_B6
Transcripts:UC008RTD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363151,916,476 - 151,917,447 (-)MPROMDB
RGD ID:6834146
Promoter ID:MM_KWN:36428
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:UC008RTB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363151,928,804 - 151,929,304 (-)MPROMDB
RGD ID:6882644
Promoter ID:EPDNEW_M4773
Type:multiple initiation site
Name:Nexn_2
Description:Mus musculus nexilin , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4774  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383152,255,362 - 152,255,422EPDNEW
RGD ID:6882646
Promoter ID:EPDNEW_M4774
Type:initiation region
Name:Nexn_1
Description:Mus musculus nexilin , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4773  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383152,265,768 - 152,265,828EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916060 AgrOrtholog
Ensembl Genes ENSMUSG00000039103 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000046045 ENTREZGENE
  ENSMUST00000046045.13 UniProtKB/Swiss-Prot
  ENSMUST00000196504.5 UniProtKB/TrEMBL
  ENSMUST00000196529.5 UniProtKB/TrEMBL
  ENSMUST00000196815.5 UniProtKB/TrEMBL
  ENSMUST00000198460 ENTREZGENE
  ENSMUST00000198460.5 UniProtKB/TrEMBL
  ENSMUST00000198648.5 UniProtKB/TrEMBL
  ENSMUST00000198750.5 UniProtKB/TrEMBL
  ENSMUST00000199423 ENTREZGENE
  ENSMUST00000199423.5 UniProtKB/TrEMBL
  ENSMUST00000199470 ENTREZGENE
  ENSMUST00000199470.5 UniProtKB/TrEMBL
  ENSMUST00000199685.2 UniProtKB/TrEMBL
  ENSMUST00000200589.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Basigin-like UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:68810 UniProtKB/Swiss-Prot
MGD MGI:1916060 ENTREZGENE
NCBI Gene 68810 ENTREZGENE
PANTHER MITOGUARDIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITOGUARDIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEXILIN UniProtKB/TrEMBL
  PTHR10075 UniProtKB/TrEMBL
Pfam I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nexn PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JDY6_MOUSE UniProtKB/TrEMBL
  A0A0G2JDZ3_MOUSE UniProtKB/TrEMBL
  A0A0G2JDZ7_MOUSE UniProtKB/TrEMBL
  A0A0G2JDZ8_MOUSE UniProtKB/TrEMBL
  A0A0G2JEX1 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JFD8_MOUSE UniProtKB/TrEMBL
  A0A0G2JFI0_MOUSE UniProtKB/TrEMBL
  A0A0G2JFT2_MOUSE UniProtKB/TrEMBL
  A0A0G2JG59_MOUSE UniProtKB/TrEMBL
  A0A0G2JGI1_MOUSE UniProtKB/TrEMBL
  E9QJX5 ENTREZGENE
  G4W8R2 ENTREZGENE, UniProtKB/TrEMBL
  G4W8R3_MOUSE UniProtKB/TrEMBL
  G4W8R4_MOUSE UniProtKB/TrEMBL
  NEXN_MOUSE UniProtKB/Swiss-Prot
  Q3TQP3 ENTREZGENE
  Q3UWU2 ENTREZGENE
  Q3UWU6 ENTREZGENE
  Q3UX39 ENTREZGENE
  Q7TPW1 ENTREZGENE
UniProt Secondary E9QJX5 UniProtKB/Swiss-Prot
  Q3TQP3 UniProtKB/Swiss-Prot
  Q3UWU2 UniProtKB/Swiss-Prot
  Q3UWU6 UniProtKB/Swiss-Prot
  Q3UX39 UniProtKB/Swiss-Prot