CDC73 (cell division cycle 73) - Rat Genome Database

Help | FTP Download | Citing RGD | Contact Us

Keyword

Gene: CDC73 (cell division cycle 73) Homo sapiens

Symbol:

CDC73

Name:

cell division cycle 73

Description:

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

C1orf28; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; cell division cycle protein 73 homolog; FLJ23316; HPTJT; HRPT2; hyperparathyroidism 2 protein; HYX; OTTHUMP00000033765; Paf1/RNA polymerase II complex component; parafibromin

Orthologs:

Mus musculus : Cdc73 (cell division cycle 73, Paf1/RNA polymerase II complex component) MGI
Rattus norvegicus : Cdc73 (cell division cycle 73)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	1	199,630,020 - 199,762,779	+	NCBI
Human Genome Assembly HuRef	1	164,326,911 - 164,459,852	+	NCBI
Human Genome Assembly GRCh37	1	193,091,088 - 193,223,945	+	NCBI
Human Genome Assembly Build 36	1	191,357,784 - 191,487,679	+	NCBI
Human Cytogenetic Map	1	q25		NCBI
Human Genome Assembly	1	189,822,817 - 189,952,713		NCBI