PTPN3 (protein tyrosine phosphatase, non-receptor type 3)

Help | FTP Download | Citing RGD | Contact Us

Keyword

Gene: PTPN3 (protein tyrosine phosphatase, non-receptor type 3) Homo sapiens

Symbol:

PTPN3

Name:

protein tyrosine phosphatase, non-receptor type 3

Description:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

cytoskeletal-associated protein tyrosine phosphatase; DKFZp686N0569; OTTHUMP00000021885; protein tyrosin phosphatase H1; protein-tyrosine phosphatase H1; PTP-H1; PTP-H1; PTPH1; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 3

Orthologs:

Mus musculus : Ptpn3 (protein tyrosine phosphatase, non-receptor type 3) MGI
Rattus norvegicus : Ptpn3 (protein tyrosine phosphatase, non-receptor type 3)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	9	112,146,989 - 112,234,766	-	NCBI
Human Genome Assembly HuRef	9	81,738,137 - 81,860,645	-	NCBI
Human Genome Assembly GRCh37	9	112,137,974 - 112,260,593	-	NCBI
Human Genome Assembly Build 36	9	111,180,337 - 111,265,557	-	NCBI
Human Cytogenetic Map	9	q31		NCBI
Human Genome Assembly	9	109,220,072 - 109,305,289		NCBI