Gene: IL36RN (interleukin 36 receptor antagonist)
Homo sapiens
Symbol:
IL36RN
Name:
interleukin 36 receptor antagonist
Description:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
family of interleukin 1-delta; FIL1; FIL1 delta; FIL1(DELTA); FIL1D; IL-1 delta; IL-1 related protein 3; IL-1-related protein 3; IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta); IL-1HY1; IL-1L1; IL-1ra homolog 1; IL1F5; IL1F5 (Canonical product IL-1F5a); IL1HY1; IL1L1; IL1RP3; IL36RA; interleukin 1 family, member 5 (delta); interleukin 1, delta; interleukin-1 delta; interleukin-1 family member 5; interleukin-1 HY1; interleukin-1 receptor antagonist homolog 1; interleukin-1-like protein 1; interleukin-36 receptor antagonist protein; MGC29840; OTTHUMP00000162015; OTTHUMP00000203697; OTTHUMP00000203698; PSORP
Orthologs:
Mus musculus : Il1f5
(interleukin 1 family, member 5 (delta))
MGI
Il36rn
(interleukin 36 receptor antagonist)
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 2 113,329,793 - 113,335,899 + NCBI Human Genome Assembly HuRef 2 106,271,122 - 106,277,233 + NCBI Human Genome Assembly GRCh37 2 113,816,215 - 113,822,321 + NCBI Human Genome Assembly Build 36 2 113,532,686 - 113,538,792 + NCBI Human Cytogenetic Map 2 q14 NCBI Human Genome Assembly 2 113,532,445 - 113,538,549 NCBI
Model
Gene Ontology Annotations
1558699 HRV2_H Heart rate variability QTL 2 (human) 1.81 Heart rate variability low-frequency power 2 59291776 208725006 Human 1300023 BP46_H Blood pressure QTL 46 (human) 2.26 .00062 Blood pressure systolic 2 75830381 218576756 Human 2289436 BW397_H Body weight QTL 397 (human) 4.04 Body weight BMI 2 85488426 156283230 Human 2289614 BW398_H Body weight QTL 398 (human) 2.56 Body weight BMI 2 99998595 125998595 Human 1559368 BW76_H Body weight QTL 76 (human) 1.77 .006 Body weight body mass index 2 103241007 129241007 Human 2302777 MAMTS9_H Mammary tumor susceptibility QTL 9 (human) .013 Mammary tumor susceptibility 2 103241007 129241007 Human 2302766 MAMTS38_H Mammary tumor susceptibility QTL 38 (human) .077 Mammary tumor susceptibility 2 107243233 116241085 Human 2289419 BW402_H Body weight QTL 402 (human) 1.91 Body fat amount percent fat 2 111249982 137249982 Human 2289438 BW403_H Body weight QTL 403 (human) 2.03 Body fat amount none 2 111249982 137249982 Human 1298440 OSTEAR11_H Osteoarthritis QTL 11 (human) 2.51 Joint/bone inflammation distal interphalangeal joint osteoarthritis 2 112693169 119989061 Human 1357310 AASTH42_H Allergic/atopic asthma related QTL 42 (human) .004 Reversible airflow obstruction 2 113186805 139186805 Human 1643465 SLIPL7_H Serum lipid level QTL 7 (human) 2 .001 Lipid level 2 113186805 139186805 Human
Gene Ontology Annotations
