Sorcs2 (sortilin-related VPS10 domain containing receptor 2) - Rat Genome Database

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Gene: Sorcs2 (sortilin-related VPS10 domain containing receptor 2) Mus musculus
Analyze
Symbol: Sorcs2
Name: sortilin-related VPS10 domain containing receptor 2
RGD ID: 1321632
MGI Page MGI
Description: Involved in intracellular protein transport and long-term synaptic depression. Located in endosome membrane; plasma membrane; and postsynaptic density. Is expressed in several structures, including brain; future spinal cord; musculature; sensory organ; and spinal cord. Orthologous to human SORCS2 (sortilin related VPS10 domain containing receptor 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: mKIAA1329; N28137; VPS10 domain receptor protein SORCS 2; VPS10 domain-containing receptor SorCS2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39536,174,524 - 36,555,541 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl536,174,524 - 36,555,483 (-)EnsemblGRCm39 Ensembl
GRCm38536,017,180 - 36,398,197 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl536,017,180 - 36,398,139 (-)EnsemblGRCm38mm10GRCm38
MGSCv37536,359,829 - 36,740,788 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36536,334,092 - 36,715,203 (-)NCBIMGSCv36mm8
Celera533,494,787 - 33,878,421 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map519.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,7-dihydropurine-6-thione  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
butane-2,3-dione  (ISO)
cantharidin  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
choline  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fenvalerate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
iron dichloride  (ISO)
isoprenaline  (EXP)
L-methionine  (EXP)
lead diacetate  (EXP)
lead(0)  (EXP,ISO)
manganese(II) chloride  (ISO)
mercaptopurine  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paraquat  (ISO)
pentane-2,3-dione  (ISO)
phenylmercury acetate  (ISO)
purine-6-thiol  (ISO)
SB 431542  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
tungsten  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11165493   PMID:11217851   PMID:12465718   PMID:12477932   PMID:12904583   PMID:14610273   PMID:14645517   PMID:15009648   PMID:15226823  
PMID:16141072   PMID:16141073   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23091165   PMID:24715575   PMID:24908487   PMID:26964886   PMID:27457814   PMID:28346477  
PMID:28378742   PMID:28469074   PMID:29405286   PMID:30061605   PMID:30840898   PMID:31156431   PMID:31898841   PMID:31988435   PMID:32325033   PMID:34611268   PMID:37897724  


Genomics

Comparative Map Data
Sorcs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39536,174,524 - 36,555,541 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl536,174,524 - 36,555,483 (-)EnsemblGRCm39 Ensembl
GRCm38536,017,180 - 36,398,197 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl536,017,180 - 36,398,139 (-)EnsemblGRCm38mm10GRCm38
MGSCv37536,359,829 - 36,740,788 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36536,334,092 - 36,715,203 (-)NCBIMGSCv36mm8
Celera533,494,787 - 33,878,421 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map519.14NCBI
SORCS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3847,192,538 - 7,742,827 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl47,192,538 - 7,742,827 (+)EnsemblGRCh38hg38GRCh38
GRCh3747,194,265 - 7,744,554 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3647,245,373 - 7,795,464 (+)NCBINCBI36Build 36hg18NCBI36
Build 3447,312,543 - 7,862,634NCBI
Celera47,098,892 - 7,646,499 (+)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef47,121,365 - 7,666,825 (+)NCBIHuRef
CHM1_147,192,978 - 7,742,776 (+)NCBICHM1_1
T2T-CHM13v2.047,165,091 - 7,714,720 (+)NCBIT2T-CHM13v2.0
Sorcs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81478,592,290 - 78,960,582 (+)NCBIGRCr8
mRatBN7.21474,371,089 - 74,735,943 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1474,371,415 - 74,735,943 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1478,813,341 - 79,177,234 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01480,054,214 - 80,418,108 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01476,499,206 - 76,863,105 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01479,538,911 - 79,912,333 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1479,538,911 - 79,912,333 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01479,176,694 - 79,547,823 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41479,968,072 - 80,344,330 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11480,096,523 - 80,344,581 (+)NCBI
Celera1473,307,871 - 73,668,512 (+)NCBICelera
Cytogenetic Map14q21NCBI
Sorcs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555143,053,071 - 3,390,125 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555143,053,127 - 3,390,125 (-)NCBIChiLan1.0ChiLan1.0
SORCS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v237,461,355 - 8,018,926 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan147,390,923 - 7,947,395 (+)NCBINHGRI_mPanPan1
PanPan1.147,259,342 - 7,805,275 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl47,259,337 - 7,803,594 (+)Ensemblpanpan1.1panPan2
SORCS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1359,319,707 - 59,679,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl359,255,848 - 59,679,049 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha361,869,645 - 62,328,037 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0359,694,699 - 60,150,946 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl359,693,881 - 60,150,928 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1359,190,682 - 59,647,586 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0359,393,438 - 59,850,032 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0359,749,003 - 60,208,135 (+)NCBIUU_Cfam_GSD_1.0
Sorcs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528565,251,269 - 65,577,361 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647718,952,959 - 19,279,198 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647718,952,965 - 19,279,053 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SORCS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl83,207,098 - 3,760,393 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.183,207,087 - 3,715,002 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.283,962,102 - 4,004,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103246549
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12743,629,273 - 43,700,888 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666113202,336 - 351,788 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sorcs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475523,479,893 - 23,659,370 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475523,346,247 - 23,657,637 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sorcs2
11821 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1971
Count of miRNA genes:757
Interacting mature miRNAs:965
Transcripts:ENSMUST00000037370, ENSMUST00000070720, ENSMUST00000135324, ENSMUST00000137040, ENSMUST00000141508
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53102427565024480Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53102427565024480Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53157045865570458Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53348866767488876Mouse
1301845Lxw4_mlupus BXSB x NZW 4 (mouse)Not determined53569446269694594Mouse
11049561Lmr24e_mleishmaniasis resistance 24e (mouse)53569446269694594Mouse
11049559Lmr24c_mleishmaniasis resistance 24c (mouse)53569446269694594Mouse
11049558Lmr24b_mleishmaniasis resistance 24b (mouse)53569446269694594Mouse
1301223Hdlq7_mHDL QTL 7 (mouse)Not determined53585456869854714Mouse
13464252Ahl10_mage related hearing loss, early onset 10 (mouse)53585456869854714Mouse
4141647Hrvhf1_mheart rate variability, high frequency 1 (mouse)Not determined3643342370433423Mouse
1301170Lith13_mlithogenic gene 13 (mouse)Not determined53649448670494598Mouse

Markers in Region
D5Jcs30  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,340,597 - 36,340,808UniSTSGRCm38
MGSCv37536,683,246 - 36,683,457UniSTSGRCm37
Celera533,820,680 - 33,820,891UniSTS
Cytogenetic Map5B3UniSTS
cM Map5 UniSTS
D5Jcs31  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,355,103 - 36,355,261UniSTSGRCm38
MGSCv37536,697,752 - 36,697,910UniSTSGRCm37
Celera533,835,297 - 33,835,455UniSTS
Cytogenetic Map5B3UniSTS
cM Map5 UniSTS
D5Jcs34  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,259,517 - 36,259,667UniSTSGRCm38
MGSCv37536,602,166 - 36,602,316UniSTSGRCm37
Celera533,739,109 - 33,739,255UniSTS
Cytogenetic Map5B3UniSTS
cM Map5 UniSTS
D5Jcs33  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,230,156 - 36,230,305UniSTSGRCm38
MGSCv37536,572,805 - 36,572,954UniSTSGRCm37
Celera533,711,236 - 33,711,375UniSTS
Cytogenetic Map5B3UniSTS
cM Map5 UniSTS
D5Jcs76  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,328,573 - 36,328,725UniSTSGRCm38
MGSCv37536,671,222 - 36,671,374UniSTSGRCm37
Celera533,808,676 - 33,808,814UniSTS
Cytogenetic Map5B3UniSTS
cM Map5 UniSTS
D5Mit75  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,304,140 - 36,304,289UniSTSGRCm38
MGSCv37536,646,789 - 36,646,938UniSTSGRCm37
Celera533,784,090 - 33,784,233UniSTS
Cytogenetic Map5B3UniSTS
cM Map520.0UniSTS
Whitehead Genetic515.3UniSTS
Whitehead/MRC_RH5478.22UniSTS
30.MMHAP29FLB6.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,018,441 - 36,018,600UniSTSGRCm38
MGSCv37536,361,090 - 36,361,249UniSTSGRCm37
Celera533,496,048 - 33,496,207UniSTS
Cytogenetic Map5B3UniSTS
Whitehead/MRC_RH5474.98UniSTS
RH125058  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,017,655 - 36,017,782UniSTSGRCm38
MGSCv37536,360,304 - 36,360,431UniSTSGRCm37
Celera533,495,262 - 33,495,389UniSTS
Cytogenetic Map5B3UniSTS
RH127225  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,110,746 - 36,110,979UniSTSGRCm38
MGSCv37536,453,395 - 36,453,628UniSTSGRCm37
Celera533,588,404 - 33,588,630UniSTS
Cytogenetic Map5B3UniSTS
cM Map518.0UniSTS
Whitehead/MRC_RH5478.32UniSTS
UniSTS:490742  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38536,204,056 - 36,205,502UniSTSGRCm38
MGSCv37536,546,705 - 36,548,151UniSTSGRCm37
Celera533,684,828 - 33,686,274UniSTS
Cytogenetic Map5B3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_030889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006504202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB093294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC115743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC133937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY004316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO428928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV784176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000037370   ⟹   ENSMUSP00000041828
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl536,174,524 - 36,555,468 (-)Ensembl
GRCm38.p6 Ensembl536,017,180 - 36,398,124 (-)Ensembl
RefSeq Acc Id: ENSMUST00000070720   ⟹   ENSMUSP00000065292
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl536,307,547 - 36,555,483 (-)Ensembl
GRCm38.p6 Ensembl536,150,203 - 36,398,139 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135324   ⟹   ENSMUSP00000123543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl536,222,720 - 36,425,823 (-)Ensembl
GRCm38.p6 Ensembl536,065,376 - 36,268,479 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137040
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl536,218,425 - 36,555,451 (-)Ensembl
GRCm38.p6 Ensembl536,061,081 - 36,398,107 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl536,308,577 - 36,523,262 (-)Ensembl
GRCm38.p6 Ensembl536,151,233 - 36,365,918 (-)Ensembl
RefSeq Acc Id: NM_030889   ⟹   NP_112151
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39536,174,524 - 36,555,483 (-)NCBI
GRCm38536,017,180 - 36,398,139 (-)NCBI
MGSCv37536,359,829 - 36,740,788 (-)RGD
Celera533,494,787 - 33,878,421 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006504202   ⟹   XP_006504265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39536,174,524 - 36,555,541 (-)NCBI
GRCm38536,017,180 - 36,398,197 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165630   ⟹   XP_036021523
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39536,174,524 - 36,540,637 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165631   ⟹   XP_036021524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39536,174,524 - 36,540,637 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_112151   ⟸   NM_030889
- Peptide Label: precursor
- UniProtKB: B2RSI2 (UniProtKB/Swiss-Prot),   B2RSI4 (UniProtKB/Swiss-Prot),   Q9EPR5 (UniProtKB/Swiss-Prot),   Q8CHA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006504265   ⟸   XM_006504202
- Peptide Label: isoform X1
- UniProtKB: Q8CHA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000065292   ⟸   ENSMUST00000070720
RefSeq Acc Id: ENSMUSP00000123543   ⟸   ENSMUST00000135324
RefSeq Acc Id: ENSMUSP00000041828   ⟸   ENSMUST00000037370
RefSeq Acc Id: XP_036021524   ⟸   XM_036165631
- Peptide Label: isoform X3
- UniProtKB: Q8CHA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036021523   ⟸   XM_036165630
- Peptide Label: isoform X2
- UniProtKB: Q8CHA4 (UniProtKB/TrEMBL)
Protein Domains
PKD   Sortilin N-terminal   VPS10

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EPR5-F1-model_v2 AlphaFold Q9EPR5 1-1159 view protein structure

Promoters
RGD ID:6886528
Promoter ID:EPDNEW_M6715
Type:initiation region
Name:Sorcs2_1
Description:Mus musculus sortilin-related VPS10 domain containing receptor2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38536,398,110 - 36,398,170EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1932289 AgrOrtholog
Ensembl Genes ENSMUSG00000029093 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000037370 ENTREZGENE
  ENSMUST00000037370.14 UniProtKB/Swiss-Prot
  ENSMUST00000070720.8 UniProtKB/TrEMBL
  ENSMUST00000135324.8 UniProtKB/TrEMBL
Gene3D-CATH 2.10.70.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.60.270 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKD_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sortilin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sortilin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VPS10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:81840 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1932289 ENTREZGENE
NCBI Gene 81840 ENTREZGENE
PANTHER SORTILIN RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PKD_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sortilin-Vps10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sortilin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sorcs2 PhenoGen
PROSITE PKD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART VPS10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Oligoxyloglucan reducing end-specific cellobiohydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49299 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RSI2 ENTREZGENE
  B2RSI4 ENTREZGENE
  D3YYF4_MOUSE UniProtKB/TrEMBL
  Q3TU45_MOUSE UniProtKB/TrEMBL
  Q8BI61_MOUSE UniProtKB/TrEMBL
  Q8BI74_MOUSE UniProtKB/TrEMBL
  Q8CHA4 ENTREZGENE, UniProtKB/TrEMBL
  Q9EPR5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2RSI2 UniProtKB/Swiss-Prot
  B2RSI4 UniProtKB/Swiss-Prot