T (brachyury, T-box transcription factor T)

Gene: T (brachyury, T-box transcription factor T) Mus musculus

Analyze

Symbol:

Name:

brachyury, T-box transcription factor T

RGD ID:

1320870

MGI Page

MGI

Description:

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in cardiac muscle cell myoblast differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including chordate embryonic development; circulatory system development; and embryonic morphogenesis. Located in cytoplasm and nucleus. Part of chromatin. Is expressed in several structures, including egg cylinder; embryo mesenchyme; future spinal cord; genitourinary system; and mesoderm. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human TBXT (T-box transcription factor T).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

B; Bra; brachyury; brachyury protein; brachyury-like 2; brachyury-like 3; cou; D17Mit170; Low; low ratio; Lr; me75; T-box transcription factor T; T1; Tbxt; Tl2; Tl3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TBXT (T-box transcription factor T)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Tbxt (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tbxt (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TBXT (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TBXT (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tbxt (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TBXT (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TBXT (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tbxt (T-box transcription factor T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TBX19 (T-box transcription factor 19)	HGNC	OrthoDB
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Tbxt (T-box transcription factor T)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TBXT (T-box transcription factor T)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tbxta	Alliance	DIOPT (PANTHER\|ZFIN)
Drosophila melanogaster (fruit fly):	byn	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tbxtb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	tbxt	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	tbxt.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	8,653,255 - 8,661,328 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	8,653,255 - 8,661,328 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	8,434,423 - 8,442,496 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	8,434,423 - 8,442,496 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	8,627,288 - 8,635,361 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	8,272,597 - 8,280,670 (+)	NCBI		MGSCv36	mm8
Celera	17	8,480,245 - 8,488,318 (+)	NCBI		Celera
Cytogenetic Map	17	A1	NCBI
cM Map	17	4.92	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive intellectual developmental disorder 40 (ISO)

chordoma (ISO)

genetic disease (ISO)

neural tube defect (ISO)

Sacral Agenesis with Vertebral Anomalies (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

5-fluorouracil (EXP)

6-propyl-2-thiouracil (ISO)

acetic acid (EXP)

all-trans-retinoic acid (ISO)

amitrole (ISO)

arsane (EXP,ISO)

arsenic atom (EXP,ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

bromochloroacetic acid (EXP)

butylated hydroxyanisole (EXP)

carbamazepine (ISO)

CGP 52608 (ISO)

chlorpyrifos (EXP)

choline (EXP)

cisplatin (ISO)

Cuprizon (ISO)

curcumin (EXP)

cypermethrin (EXP)

fluoxetine (EXP)

folic acid (EXP,ISO)

glycidol (ISO)

L-methionine (EXP)

lead diacetate (EXP)

lead(0) (ISO)

methimazole (ISO)

methoxyacetic acid (EXP)

Monobutylphthalate (EXP)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP)

raloxifene (ISO)

resveratrol (EXP)

SB 431542 (ISO)

sodium arsenite (EXP,ISO)

sulfadimethoxine (ISO)

testosterone (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anatomical structure morphogenesis (IMP)

anterior/posterior pattern specification (IMP)

bone morphogenesis (IGI)

cardiac muscle cell differentiation (NAS)

cardiac muscle cell myoblast differentiation (IMP,ISO)

cell fate specification (IBA)

cell population proliferation (IMP)

cellular response to retinoic acid (ISO)

determination of heart left/right asymmetry (IMP)

embryonic skeletal system development (IMP)

heart morphogenesis (IBA,ISO)

mesoderm development (IMP)

mesoderm formation (IBA)

mesoderm migration involved in gastrulation (IMP)

negative regulation of transcription by RNA polymerase II (IDA)

neural plate morphogenesis (IMP)

neural tube closure (IMP)

notochord development (IMP)

notochord formation (IMP)

penetration of zona pellucida (IMP)

positive regulation of cell population proliferation (IMP)

positive regulation of DNA-templated transcription (IEA)

positive regulation of transcription by RNA polymerase II (IGI,IMP,ISO)

post-anal tail morphogenesis (IGI,IMP)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA,IDA)

signal transduction involved in regulation of gene expression (IDA)

somitogenesis (IBA,IMP)

transcription by RNA polymerase II (IGI)

vasculogenesis (IMP)

Cellular Component

chromatin (IBA,IDA,IMP,ISO)

cytoplasm (IDA)

nucleoplasm (ISO,TAS)

nucleus (IBA,IDA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IDA,ISO)

protein binding (IPI)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IDA,ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (IPI,ISO)

sequence-specific DNA binding (IDA)

sequence-specific double-stranded DNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal allantois morphology (IAGP)

abnormal axial mesoderm morphology (IAGP)

abnormal bone ossification (IAGP)

abnormal cervical atlas morphology (IAGP)

abnormal cervical vertebrae morphology (IAGP)

abnormal colon morphology (IAGP)

abnormal dorsal aorta morphology (IEA)

abnormal embryo development (IAGP)

abnormal epidermal layer morphology (IEA)

abnormal forelimb bud morphology (IEA)

abnormal head shape (IEA)

abnormal heart looping (IAGP)

abnormal heart tube morphology (IAGP)

abnormal limb bud morphology (IAGP)

abnormal lumbar vertebrae morphology (IAGP)

abnormal mesoderm development (IAGP)

abnormal nervous system development (IEA)

abnormal neural fold formation (IAGP)

abnormal neural tube morphology (IAGP)

abnormal notochord morphology (IAGP)

abnormal nucleus pulposus morphology (IAGP)

abnormal odontoid process morphology (IAGP)

abnormal pelvic girdle bone morphology (IEA)

abnormal pericardial cavity morphology (IEA)

abnormal placenta development (IEA)

abnormal posterior primitive streak morphology (IAGP)

abnormal prechordal plate morphology (IAGP)

abnormal primitive streak formation (IAGP)

abnormal roof plate morphology (IAGP)

abnormal rostral-caudal axis patterning (IAGP)

abnormal rostral-caudal body axis extension (IEA)

abnormal sacral vertebrae morphology (IAGP)

abnormal somite development (IAGP)

abnormal spinal cord morphology (IAGP)

abnormal tail bud morphology (IAGP)

abnormal tail development (IEA)

abnormal tail morphology (IAGP)

abnormal thoracic vertebrae morphology (IEA)

abnormal vertebrae morphology (IAGP)

abnormal vertebral arch development (IAGP)

abnormal vertebral body development (IAGP)

abnormal vertebral body morphology (IAGP)

absent allantois (IAGP)

absent anus (IEA)

absent caudal vertebrae (IEA)

absent forelimb buds (IAGP)

absent hindlimb buds (IAGP)

absent notochord (IAGP)

absent primitive node (IAGP)

absent sacral vertebrae (IEA)

absent somites (IAGP)

absent tail (IAGP)

absent tail bud (IAGP)

absent vertebrae (IAGP)

absent vertebral arch (IEA)

absent vertebral body (IAGP)

bleb (IEA)

caudal body truncation (IAGP)

cervical vertebral fusion (IAGP)

curly tail (IAGP)

decreased body size (IAGP)

decreased caudal vertebrae number (IAGP)

decreased embryo size (IEA)

decreased litter size (IEA)

decreased presacral vertebrae number (IAGP)

decreased rib number (IAGP)

decreased survivor rate (IAGP)

decreased ventral ectodermal ridge size (IAGP)

delayed heart development (IEA)

distended pericardium (IAGP)

distended urinary bladder (IAGP)

edema (IAGP)

embryonic growth arrest (IAGP)

embryonic growth retardation (IAGP)

embryonic lethality (IAGP)

embryonic lethality between implantation and somite formation, complete penetrance (IAGP)

embryonic lethality between somite formation and embryo turning, complete penetrance (IAGP)

embryonic lethality during organogenesis, complete penetrance (IAGP)

embryonic lethality during organogenesis, incomplete penetrance (IAGP)

embryonic lethality, complete penetrance (IAGP)

failure of heart looping (IAGP)

failure of initiation of embryo turning (IAGP)

fusion of vertebral arches (IAGP)

head tilt (IAGP)

hemopericardium (IEA)

hemorrhage (IEA)

hindlimb paralysis (IAGP)

incomplete caudal neuropore closure (IAGP)

incomplete embryo turning (IAGP)

incomplete somite formation (IAGP)

kinked neural tube (IAGP)

kinked tail (IAGP)

male infertility (IAGP)

meningocele (IAGP)

meningomyelocele (IEA)

neonatal lethality, incomplete penetrance (IAGP)

no abnormal phenotype detected (IAGP)

notochord degeneration (IEA)

open neural tube (IAGP)

perinatal lethality, incomplete penetrance (IAGP)

postnatal lethality (IAGP)

postnatal lethality, complete penetrance (IAGP)

prenatal lethality (IEA)

prenatal lethality, complete penetrance (IEA)

preweaning lethality, incomplete penetrance (IEA)

reduced male fertility (IAGP)

rib fusion (IAGP)

short ribs (IAGP)

short tail (IAGP)

spina bifida occulta (IAGP)

split notochord (IAGP)

thin tail (IAGP)

thoracic vertebral fusion (IAGP)

transmission ratio distortion (IAGP)

vertebral fusion (IAGP)

vestigial tail (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	MGDs mouse GO annotations	MGD data from the GO Consortium
2.	MGD IEA	MGD IEA
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:305895	PMID:321329	PMID:419532	PMID:455464	PMID:521667	PMID:600262	PMID:628373	PMID:692659	PMID:924142	PMID:1003081	PMID:1218735	PMID:1225760
PMID:1256555	PMID:1295727	PMID:1299362	PMID:1363228	PMID:1391349	PMID:1421767	PMID:1495973	PMID:1572534	PMID:1581629	PMID:1592235	PMID:1665374	PMID:1676981
PMID:1689462	PMID:1794044	PMID:1794053	PMID:1799792	PMID:1820026	PMID:1821859	PMID:1845916	PMID:1859671	PMID:1922339	PMID:1936961	PMID:2016041	PMID:2076813
PMID:2081600	PMID:2132728	PMID:2154694	PMID:2272509	PMID:2318411	PMID:2345346	PMID:2570638	PMID:2658196	PMID:2717616	PMID:2725545	PMID:2759663	PMID:2767429
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PMID:18600225	PMID:18617531	PMID:18691704	PMID:18701545	PMID:18710940	PMID:18729134	PMID:18781635	PMID:18794329	PMID:18794365	PMID:18800919	PMID:18929642	PMID:18930042
PMID:18974875	PMID:19056682	PMID:19056886	PMID:19094029	PMID:19103193	PMID:19156687	PMID:19168680	PMID:19174539	PMID:19191225	PMID:19228964	PMID:19234065	PMID:19362612
PMID:19379695	PMID:19439496	PMID:19515997	PMID:19605690	PMID:19615442	PMID:19660449	PMID:19666828	PMID:19701191	PMID:19705445	PMID:19706423	PMID:19706528	PMID:19720144
PMID:19753101	PMID:19786569	PMID:19795512	PMID:19796622	PMID:19801444	PMID:19841259	PMID:19853565	PMID:19877283	PMID:19906845	PMID:19998061	PMID:20040491	PMID:20211162
PMID:20221402	PMID:20233719	PMID:20350929	PMID:20412781	PMID:20436477	PMID:20484223	PMID:20484740	PMID:20519941	PMID:20573697	PMID:20596238	PMID:20630950	PMID:20637190
PMID:20689803	PMID:20704721	PMID:20708584	PMID:20730911	PMID:20809182	PMID:20826531	PMID:20876643	PMID:20941375	PMID:21040460	PMID:21045827	PMID:21056461	PMID:21069829
PMID:21149574	PMID:21163256	PMID:21246658	PMID:21267068	PMID:21283715	PMID:21337463	PMID:21368122	PMID:21394824	PMID:21423341	PMID:21445260	PMID:21466802	PMID:21483770
PMID:21554866	PMID:21555575	PMID:21606373	PMID:21632880	PMID:21652651	PMID:21660050	PMID:21677750	PMID:21693517	PMID:21731673	PMID:21763783	PMID:21768372	PMID:21799763
PMID:21816365	PMID:21816850	PMID:21873635	PMID:21896659	PMID:21898690	PMID:21953618	PMID:21966279	PMID:21998041	PMID:22013995	PMID:22072575	PMID:22075149	PMID:22110054
PMID:22164283	PMID:22342906	PMID:22354863	PMID:22475651	PMID:22479388	PMID:22546692	PMID:22573616	PMID:22669107	PMID:22675207	PMID:22678773	PMID:22698281	PMID:22912414
PMID:22939930	PMID:22949634	PMID:22954964	PMID:22988430	PMID:22990867	PMID:22992956	PMID:22995555	PMID:23085236	PMID:23154415	PMID:23213408	PMID:23213481	PMID:23359409
PMID:23383217	PMID:23406901	PMID:23436999	PMID:23469192	PMID:23487311	PMID:23521771	PMID:23552073	PMID:23651855	PMID:23690951	PMID:23712942	PMID:23747598	PMID:23760955
PMID:23763947	PMID:23824574	PMID:23825703	PMID:24123507	PMID:24131634	PMID:24284205	PMID:24318810	PMID:24331926	PMID:24332837	PMID:24335282	PMID:24475213	PMID:24508530
PMID:24558432	PMID:24596343	PMID:24616493	PMID:24631216	PMID:24632399	PMID:24633704	PMID:24698271	PMID:24706806	PMID:24801048	PMID:24859004	PMID:24891386	PMID:24928429
PMID:25009997	PMID:25020278	PMID:25115237	PMID:25152336	PMID:25209090	PMID:25219788	PMID:25371364	PMID:25412078	PMID:25480920	PMID:25511461	PMID:25512563	PMID:25536399
PMID:25569111	PMID:25588837	PMID:25641698	PMID:25739401	PMID:25805847	PMID:25813538	PMID:25907228	PMID:25922526	PMID:25977363	PMID:26084695	PMID:26159997	PMID:26269429
PMID:26305214	PMID:26329597	PMID:26393908	PMID:26441343	PMID:26453549	PMID:26494787	PMID:26496195	PMID:26498761	PMID:26534985	PMID:26593875	PMID:26678520	PMID:26780186
PMID:26809587	PMID:26969725	PMID:26975355	PMID:27006501	PMID:27026076	PMID:27061115	PMID:27217206	PMID:27226536	PMID:27239041	PMID:27256596	PMID:27292645	PMID:27297885
PMID:27369076	PMID:27411055	PMID:27453501	PMID:27466203	PMID:27515175	PMID:27521049	PMID:27586544	PMID:27713415	PMID:27760115	PMID:27870829	PMID:27881714	PMID:27894818
PMID:27930333	PMID:28009287	PMID:28087629	PMID:28174238	PMID:28182636	PMID:28188179	PMID:28196692	PMID:28254784	PMID:28322735	PMID:28389228	PMID:28445719	PMID:28565025
PMID:28619992	PMID:28826820	PMID:28839193	PMID:28854362	PMID:28875501	PMID:28882402	PMID:29084802	PMID:29138255	PMID:29141987	PMID:29168693	PMID:29203676	PMID:29378823
PMID:29412136	PMID:29467473	PMID:29618843	PMID:29636380	PMID:29915126	PMID:29964027	PMID:30026265	PMID:30061166	PMID:30189017	PMID:30201686	PMID:30297839	PMID:30380057
PMID:30446626	PMID:30530745	PMID:30592646	PMID:30661984	PMID:30842446	PMID:30940539	PMID:30959515	PMID:31092598	PMID:31107948	PMID:31143371	PMID:31189761	PMID:31232685
PMID:31235634	PMID:31260508	PMID:31276560	PMID:31301300	PMID:31371508	PMID:31597657	PMID:31792383	PMID:31794640	PMID:31909538	PMID:31950080	PMID:32156757	PMID:32296071
PMID:32376682	PMID:32439762	PMID:32450229	PMID:32521258	PMID:32523119	PMID:32541007	PMID:32579954	PMID:32597756	PMID:32628936	PMID:32855167	PMID:33051257	PMID:33184218
PMID:33230114	PMID:33247143	PMID:33308481	PMID:33420489	PMID:33454424	PMID:33929320	PMID:33951437	PMID:33999917	PMID:34168324	PMID:34256037	PMID:34446717	PMID:34601382
PMID:34671097	PMID:34672258	PMID:34679163	PMID:34686326	PMID:34769078	PMID:34822716	PMID:34887431	PMID:35017475	PMID:35177595	PMID:35276131	PMID:35297517	PMID:35440748
PMID:35514236	PMID:35608036	PMID:35726782	PMID:35876795	PMID:35950911	PMID:35988542	PMID:35998584	PMID:36007540	PMID:36123354	PMID:36142249	PMID:36154671	PMID:36197846
PMID:36517595	PMID:36717694	PMID:36913092	PMID:37012455	PMID:37024462	PMID:37080203	PMID:37163450	PMID:37217538	PMID:37315133	PMID:37390294	PMID:37414952	PMID:37633271
PMID:37709743	PMID:37761995	PMID:37852970	PMID:37940010	PMID:38110169	PMID:38345319	PMID:38418917

Genomics

Comparative Map Data

T
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	8,653,255 - 8,661,328 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	8,653,255 - 8,661,328 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	8,434,423 - 8,442,496 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	8,434,423 - 8,442,496 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	8,627,288 - 8,635,361 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	8,272,597 - 8,280,670 (+)	NCBI		MGSCv36	mm8
Celera	17	8,480,245 - 8,488,318 (+)	NCBI		Celera
Cytogenetic Map	17	A1	NCBI
cM Map	17	4.92	NCBI

TBXT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	166,157,656 - 166,168,655 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	166,157,656 - 166,168,700 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	166,571,144 - 166,582,143 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	166,491,076 - 166,502,121 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	166,541,496 - 166,552,542	NCBI
Celera	6	167,310,712 - 167,321,757 (-)	NCBI		Celera
Cytogenetic Map	6	q27	NCBI
HuRef	6	164,037,863 - 164,048,876 (-)	NCBI		HuRef
CHM1_1	6	166,835,290 - 166,846,303 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	167,527,458 - 167,538,457 (-)	NCBI		T2T-CHM13v2.0

Tbxt
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	54,845,674 - 54,859,340 (-)	NCBI		GRCr8
mRatBN7.2	1	52,298,104 - 52,309,813 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	52,298,099 - 52,305,864 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	52,999,608 - 53,007,373 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	58,991,427 - 58,999,192 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	53,075,196 - 53,082,961 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	52,887,067 - 52,900,691 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	52,887,067 - 52,894,832 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	54,139,554 - 54,147,385 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	46,937,223 - 46,944,988 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	46,940,188 - 46,947,933 (-)	NCBI
Celera	1	48,061,384 - 48,069,149 (-)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

Tbxt
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955439	15,676,095 - 15,683,554 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955439	15,675,680 - 15,683,542 (+)	NCBI	ChiLan1.0	ChiLan1.0

TBXT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	186,353,564 - 186,363,413 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	184,249,368 - 184,259,217 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	164,112,117 - 164,122,253 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	169,095,723 - 169,106,595 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	169,095,723 - 169,106,595 (-)	Ensembl	panpan1.1		panPan2

TBXT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	54,183,495 - 54,192,331 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	54,183,153 - 54,192,352 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	54,970,966 - 54,979,790 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	54,360,266 - 54,369,833 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	54,360,928 - 54,369,833 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	54,257,349 - 54,266,189 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	54,107,519 - 54,116,264 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	54,733,858 - 54,742,687 (-)	NCBI		UU_Cfam_GSD_1.0

Tbxt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	148,774,775 - 148,782,886 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936489	16,027,359 - 16,035,041 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936489	16,027,359 - 16,035,041 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TBXT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	2,717,165 - 2,725,601 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	2,717,165 - 2,725,561 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	3,857,228 - 3,861,219 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TBXT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	93,854,086 - 93,864,910 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	93,855,534 - 93,864,507 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	65,656,160 - 65,666,958 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tbxt
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624785	13,058,444 - 13,066,719 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624785	13,058,520 - 13,066,607 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in T
241 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	538
Count of miRNA genes:	382
Interacting mature miRNAs:	449
Transcripts:	ENSMUST00000074667, ENSMUST00000136922, ENSMUST00000177118
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357452	Vtbt18_m	vertebral trabecular bone trait 18 (mouse)			Not determined		17	1	20975022	Mouse
1302196	Myaa1_m	modifier of Yaa 1 (mouse)			Not determined		17	1	20975022	Mouse
1357902	Obq19_m	obesity QTL 19 (mouse)			Not determined		17	1	25662076	Mouse
12910982	Pifs2_m	peptide-induced fatal syndrome 2 (mouse)					17	1	26189355	Mouse
1357743	Lith3_m	lithogenic gene 3 (mouse)			Not determined		17	1	26194456	Mouse
1301615	Cfld3_m	cystic fibrosis lung disease 3 (mouse)			Not determined		17	1	27081639	Mouse
1300613	Pcyts4_m	plasmacytoma susceptibility 4 (mouse)			Not determined		17	1	27081639	Mouse
1302100	Circp2_m	circadian photosensitivity 2 (mouse)			Not determined		17	1	29198453	Mouse
12910527	Nrq1a_m	noise-induced hearing loss resistant QTL 1a (mouse)					17	1	29198453	Mouse
12910528	Nrq1_m	noise-induced hearing loss resistant QTL 1 (mouse)					17	1	29198453	Mouse
13524851	Asrq8_m	acoustic startle response 8 (mouse)					17	1	31030170	Mouse
10412276	Leci2_m	leukocyte endothelial cell interactions 2 (mouse)			Not determined		17	3348175	37348299	Mouse
1357680	Idd23_m	insulin dependent diabetes susceptibility 23 (mouse)			Not determined		17	3974890	26401133	Mouse
1300890	Bhr3_m	bronchial hyperresponsiveness 3 (mouse)			Not determined		17	3974890	48866091	Mouse
1301327	Lmr7_m	leishmaniasis resistance 7 (mouse)			Not determined		17	4854752	27715939	Mouse
4141215	Mnic1_m	macronutrient intake, carbohydrate 1 (mouse)			Not determined			4854752	45670266	Mouse
1300706	Alan1_m	alloantigen response 1 (mouse)			Not determined		17	4854752	46469702	Mouse
1357789	Kdnw3_m	kidney weight 3 (mouse)			Not determined		17	4854752	47885665	Mouse
4141272	Tfv1_m	total food volume 1 (mouse)			Not determined			4854752	65637357	Mouse
10043949	Pbft7_m	percent body fat 7 (mouse)			Not determined		17	6893936	40893936	Mouse
4141608	Phl1_m	progressive hearing loss 1 (mouse)			Not determined		17	7875843	29487423	Mouse
13824987	Flal1_m	fatty liver accumulation QTL 1, females only (mouse)					17	8218832	11218887	Mouse
1301935	Skull24_m	skull morphology 24 (mouse)			Not determined		17	8584914	42585149	Mouse
1300787	Cd8mts5_m	CD8 memory T cell subset 5 (mouse)			Not determined		17	8584914	42585149	Mouse

Markers in Region

X51683

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	17	8,442,269 - 8,442,373	UniSTS	GRCm38
MGSCv37	17	8,635,134 - 8,635,238	UniSTS	GRCm37
Celera	17	8,488,091 - 8,488,195	UniSTS
Cytogenetic Map	17	A1	UniSTS
cM Map	17	4.02	UniSTS
Whitehead/MRC_RH	17	70.74	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
MGSCv37	17	8,634,462 - 8,634,784	UniSTS	GRCm37
MGSCv37	17	8,628,251 - 8,629,062	UniSTS	GRCm37
MGSCv37	17	8,635,064 - 8,635,327	UniSTS	GRCm37
MGSCv37	17	8,629,003 - 8,629,893	UniSTS	GRCm37
Celera	17	8,488,021 - 8,488,284	UniSTS
Celera	17	8,481,960 - 8,482,850	UniSTS
Celera	17	8,481,208 - 8,482,019	UniSTS
Celera	17	8,487,419 - 8,487,741	UniSTS
Cytogenetic Map	17	A1	UniSTS
cM Map	17	4.02	UniSTS
cM Map	17	4.02	UniSTS
cM Map	17	4.02	UniSTS
cM Map	17	4.02	UniSTS
cM Map	17	4.02	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	17	A1	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	17	A1	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	17	A1	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	17	A1	UniSTS
cM Map	17	4.02	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	17	8,436,138 - 8,437,028	UniSTS	GRCm38
MGSCv37	17	8,629,003 - 8,629,893	UniSTS	GRCm37
Celera	17	8,481,960 - 8,482,850	UniSTS
Cytogenetic Map	17	A1	UniSTS
cM Map	17	4.02	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	17	8,441,597 - 8,441,919	UniSTS	GRCm38
MGSCv37	17	8,634,462 - 8,634,784	UniSTS	GRCm37
Celera	17	8,487,419 - 8,487,741	UniSTS
Cytogenetic Map	17	A1	UniSTS
cM Map	17	4.02	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	17	A1	UniSTS
cM Map	17	4.02	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	17	A1	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	17	8,435,386 - 8,436,197	UniSTS	GRCm38
MGSCv37	17	8,628,251 - 8,629,062	UniSTS	GRCm37
Celera	17	8,481,208 - 8,482,019	UniSTS
Cytogenetic Map	17	A1	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	17	8,442,199 - 8,442,462	UniSTS	GRCm38
MGSCv37	17	8,635,064 - 8,635,327	UniSTS	GRCm37
Celera	17	8,488,021 - 8,488,284	UniSTS
Cytogenetic Map	17	A1	UniSTS

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	17	A1	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_009309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC154579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF466883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC120807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X51683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000074667 ⟹ ENSMUSP00000074236

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	17	8,653,255 - 8,661,328 (+)	Ensembl
GRCm38.p6 Ensembl	17	8,434,423 - 8,442,496 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000136922 ⟹ ENSMUSP00000119581

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	17	8,653,757 - 8,655,824 (+)	Ensembl
GRCm38.p6 Ensembl	17	8,434,925 - 8,436,992 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000177118 ⟹ ENSMUSP00000135526

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	17	8,654,243 - 8,660,574 (+)	Ensembl
GRCm38.p6 Ensembl	17	8,435,411 - 8,441,742 (+)	Ensembl

RefSeq Acc Id:

NM_009309 ⟹ NP_033335

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	17	8,653,255 - 8,661,328 (+)	NCBI
GRCm38	17	8,434,423 - 8,442,496 (+)	NCBI
MGSCv37	17	8,627,288 - 8,635,361 (+)	RGD
Celera	17	8,480,245 - 8,488,318 (+)	RGD
cM Map	17		ENTREZGENE

Sequence:

show sequence

GGCTCCGCAGAGTGACCCTTTTTCTTGGAAAAGCGGTGGCGAGAGAAGTGAAGGTGGCTGTTGG
GTAGGGAGTCAAGACTCCTGGAAGGTGGAGAGGGTGGCGGGAGGATGAGCTCGCCGGGCACAGA
GAGCGCAGGGAAGAGCCTGCAGTACCGAGTGGACCACCTGCTCAGCGCCGTGGAGAGCGAGCTG
CAGGCGGGCAGCGAGAAGGGAGACCCCACCGAACGCGAACTGCGAGTGGGCCTGGAGGAGAGCG
AGCTGTGGCTGCGCTTCAAGGAGCTAACTAACGAGATGATTGTGACCAAGAACGGCAGGAGGAT
GTTCCCGGTGCTGAAGGTAAATGTGTCAGGCCTGGACCCCAATGCCATGTACTCTTTCTTGCTG
GACTTCGTGACGGCTGACAACCACCGCTGGAAATATGTGAACGGGGAGTGGGTACCTGGGGGCA
AACCAGAGCCTCAGGCGCCCAGCTGCGTCTACATCCACCCAGACTCGCCCAATTTTGGGGCCCA
CTGGATGAAGGCGCCTGTGTCTTTCAGCAAAGTCAAACTCACCAACAAGCTCAATGGAGGGGGA
CAGATCATGTTAAACTCCTTGCATAAGTATGAACCTCGGATTCACATCGTGAGAGTTGGGGGCC
CGCAACGCATGATCACCAGCCACTGCTTTCCCGAGACCCAGTTCATAGCTGTGACTGCCTACCA
GAATGAGGAGATTACAGCCCTTAAAATTAAATACAACCCATTTGCTAAAGCCTTCCTTGATGCC
AAAGAAAGAAACGACCACAAAGATGTAATGGAGGAACCGGGGGACTGCCAGCAGCCGGGGTATT
CCCAATGGGGGTGGCTTGTTCCTGGTGCTGGCACCCTCTGCCCGCCTGCCAGCTCCCACCCTCA
GTTTGGAGGCTCGCTCTCTCTCCCCTCCACACACGGCTGTGAGAGGTACCCAGCTCTAAGGAAC
CACCGGTCATCGCCCTACCCCAGCCCCTATGCTCATCGGAACAGCTCTCCAACCTATGCGGACA
ATTCATCTGCTTGTCTGTCCATGCTGCAGTCCCATGATAACTGGTCTAGCCTCGGAGTGCCTGG
CCACACCAGCATGCTGCCTGTGAGTCATAACGCCAGCCCACCTACTGGCTCTAGCCAGTATCCC
AGTCTCTGGTCTGTGAGCAATGGTACCATCACCCCAGGCTCCCAGACAGCTGGGGTGTCCAACG
GGCTGGGAGCTCAGTTCTTTCGAGGCTCCCCTGCACATTACACACCACTGACGCACACGGTCTC
AGCTGCCACGTCCTCGTCTTCTGGTTCTCCGATGTATGAAGGGGCTGCTACAGTCACAGACATT
TCTGACAGCCAGTATGACACGGCCCAAAGCCTCCTCATAGCCTCGTGGACACCTGTGTCACCCC
CATCTATGTGAATTGAACTTTCCTCCATGTGCTGAGACTTGTAACAACCGGTGTCAACTGGATC
TTCTAGGCTCAAAGTGGCAGGCTCTTGGGACAAGGGAAAAATAAATAAATAAAAGCTAGATACT
AACAACTCCATTTTCAAATAAGAGCAATAATACATGTCCTATAATCATGTTCTACAGCCTCTTG
TTTGATACCTACAGTAGTGATATGTGTCCTACATTATGAAGCCAAGGACAGAGAGACGGCTGTG
GTCCAGTTTTTTGTGACTGGCAGTTAATCAGAGTCCTTTGCTAGGTAGGGTCCTATATCTTGTG
TTTCTCTACAACATATATGTGACTTTGAAATCCTGGAATTCGTCCACCCCCTGTCCTACTTTAG
TGAGACACAAGGTACACCTCTAATGTCCTCCCTTGTTGCCTTAGAGTAGTTAACTTTGAGGACA
GAAAAAAGCATAGCCAGAAGATTGTAACTGAACCGTCAACTGTTCTGCCCTTGGAACATGCCTA
CTTTAAGCACACGTAGCTTTTTGTGTTGGGAAGTCAACTGTATGGATACTTTTCTGTTGACAAA
GTAGCCAAAGACAATCTGCAGAAAGTGTTTTCTGCACAATAAAGGCAATATATAGCACCTGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_033335	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI20808	(Get FASTA)	NCBI Sequence Viewer
	AAM21001	(Get FASTA)	NCBI Sequence Viewer
	CAA35985	(Get FASTA)	NCBI Sequence Viewer
	EDL02101	(Get FASTA)	NCBI Sequence Viewer
	EDL02102	(Get FASTA)	NCBI Sequence Viewer
	EDL02103	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000074236
	ENSMUSP00000074236.3
	ENSMUSP00000119581.2
	ENSMUSP00000135526.2
GenBank Protein	P20293	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_033335 ⟸ NM_009309

- UniProtKB:

P20293 (UniProtKB/Swiss-Prot), Q78ZW9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSPGTESAGKSLQYRVDHLLSAVESELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIV
TKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVTADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPD
SPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQF
IAVTAYQNEEITALKIKYNPFAKAFLDAKERNDHKDVMEEPGDCQQPGYSQWGWLVPGAGTLCP
PASSHPQFGGSLSLPSTHGCERYPALRNHRSSPYPSPYAHRNSSPTYADNSSACLSMLQSHDNW
SSLGVPGHTSMLPVSHNASPPTGSSQYPSLWSVSNGTITPGSQTAGVSNGLGAQFFRGSPAHYT
PLTHTVSAATSSSSGSPMYEGAATVTDISDSQYDTAQSLLIASWTPVSPPSM

hide sequence

RefSeq Acc Id:

ENSMUSP00000135526 ⟸ ENSMUST00000177118

RefSeq Acc Id:

ENSMUSP00000074236 ⟸ ENSMUST00000074667

RefSeq Acc Id:

ENSMUSP00000119581 ⟸ ENSMUST00000136922

Protein Domains

T-box

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P20293-F1-model_v2	AlphaFold	P20293	1-436	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:98472	AgrOrtholog
Ensembl Genes	ENSMUSG00000062327	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000074667	ENTREZGENE
	ENSMUST00000074667.9	UniProtKB/Swiss-Prot
	ENSMUST00000136922.8	UniProtKB/TrEMBL
	ENSMUST00000177118.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.820	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	p53-like_TF_DNA-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	T-box_DNA-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	T-box_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_Brachyury	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_T-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_T-box_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:20997	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:98472	ENTREZGENE
NCBI Gene	20997	ENTREZGENE
PANTHER	PTHR11267	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	T-BOX TRANSCRIPTION FACTOR T	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	T-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	T	PhenoGen
PRINTS	BRACHYURY	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TBOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	TBOX_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TBOX_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TBOX_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	TBOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49417	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	D3Z1X4_MOUSE	UniProtKB/TrEMBL
	H3BKU2_MOUSE	UniProtKB/TrEMBL
	P20293	ENTREZGENE
	Q78ZW9	ENTREZGENE, UniProtKB/TrEMBL
	TBXT_MOUSE	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-11-16	T	brachyury, T-box transcription factor T		brachyury	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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