Myo7a<sup>tnd</sup>/Hubr (myosin VIIA; ENU induced tornado mutant, Hubr) - Rat Genome Database

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Gene: Myo7atnd/Hubr (myosin VIIA; ENU induced tornado mutant, Hubr) Rattus norvegicus
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Symbol: Myo7atnd/Hubr
Name: myosin VIIA; ENU induced tornado mutant, Hubr
RGD ID: 13204705
Description: ENU induced an A-to-T transversion at position 362 caused a premature stopcodon in exon 5 in the middle of the myosin head encoding sequence and thereby most likely results in a complete loss of function of the rat Myo7a gene.
ASSOCIATED WITH abnormal auditory brainstem response; abnormal cochlear hair cell stereociliary bundle morphology; abnormal vestibular system physiology
Type: allele  of Myo7a  
Previously known as: Myo7atnd-1Hubr; Myo7atnd /Hubr; Myo7a^[tnd]/Hubr; Myo7atnd /Hubr
Is Marker For: Strains:   W-Myo7atnd/Hubr  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics. Smits BM, etal., Genetics. 2005 Aug;170(4):1887-96. Epub 2005 Jun 18.

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Myo7atnd/Hubr-var1 chr1 152392431 152392431 T A point_mutation mRatBN7.2
Myo7atnd/Hubr-var1 chr1 163049850 163049850 T A point_mutation Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Myo7atnd/Hubr
W-Myo7atnd/Hubr    


Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-14 Myo7atnd/Hubr  myosin VIIA; ENU induced tornado mutant, Hubr  Myo7atnd /Hubr  myosin VIIA; ENU induced tornado mutant, Hubr  Symbol changed 629549 APPROVED