HOXD4 (homeobox D4) - Rat Genome Database

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Keyword

Gene: HOXD4 (homeobox D4) Homo sapiens

Symbol:

HOXD4

Name:

homeobox D4

Description:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

HHO.C13; homeo box d4; homeobox protein HHO.C13; homeobox protein Hox-4B; homeobox protein Hox-5.1; homeobox protein Hox-D4; Hox-4.2; Hox-4.2, mouse, homolog of homeo box X; HOX-5.1; HOX4; HOX4B; OTTHUMP00000163340

Orthologs:

Mus musculus : Hoxd4 (homeobox D4) MGI
Rattus norvegicus : Hoxd4 (homeo box D4)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	176,410,982 - 176,412,820	+	NCBI
Human Genome Assembly HuRef	2	168,892,961 - 168,894,799	+	NCBI
Human Genome Assembly GRCh37	2	177,016,113 - 177,017,951	+	NCBI
Human Genome Assembly Build 36	2	176,724,359 - 176,726,197	+	NCBI
Human Cytogenetic Map	2	q31.1		NCBI
Human Genome Assembly	2	176,841,619 - 176,843,454		NCBI