Gene: Sf3b4 (splicing factor 3b, subunit 4)
Mus musculus |
| Symbol: |
Sf3b4
|
| Name: |
splicing factor 3b, subunit 4
|
| Description: |
ENCODES a protein that exhibits nucleic acid binding (inferred); nucleotide binding (inferred); RNA binding (inferred); INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; FOUND IN spliceosomal complex (ortholog); U12-type spliceosomal complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,4-methylenedioxymethamphetamine |
| Type: |
protein-coding
|
| RefSeq Status: |
PROVISIONAL
|
| Also known as: |
49kDa; MGC36369; MGC36564; OTTMUSP00000024556; Sap49; SF3b49; SF3b50; spliceosome associated protein 49; splicing factor 3B subunit 4; splicing factor 3b, subunit 4, 49kD
|
| Orthologs: |
Homo sapiens : SF3B4
(splicing factor 3b, subunit 4, 49kDa)
HGNC
Rattus norvegicus : Sf3b4
(splicing factor 3b, subunit 4)
|
| Related Pseudogenes: |
Gm7935
|
| Latest Assembly: |
Mouse Genome Assembly Build 37
|
| Position: |
| Map | Chr | Position | Strand | Source |
|---|
Mouse Genome Assembly GRCm38 | 3 | 96,172,550 - 96,177,564 | + | NCBI | Mouse cM Map | 3 | | + | NCBI | Mouse Celera Assembly | 3 | 97,608,698 - 97,613,377 | + | NCBI | Mouse Genome Assembly Build 37 | 3 | 95,976,473 - 95,981,487 | + | NCBI | Mouse Genome Assembly Build 36.1 | 3 | 95,976,473 - 95,981,487 | + | NCBI | Mouse Cytogenetic Map | 3 | F2.1 | | NCBI |
|
| Model |
|
 Gene-Chemical Interaction Annotations
| (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1320131 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SF3B4 mRNA | CTD | PMID:22079256 | | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SF3B4 mRNA | CTD | PMID:20702594 | | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SF3B4 mRNA | CTD | PMID:20702594 PMID:21570461 | | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SF3B4 mRNA | CTD | PMID:19465110 | | 2,4-dinitrotoluene | affects expression | ISO | RGD:1309667 | 6480464 | 2,4-dinitrotoluene affects the expression of SF3B4 mRNA | CTD | PMID:21346803 | | 3,3',4,4',5-pentachlorobiphenyl | affects expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl affects the expression of SF3B4 mRNA | CTD | PMID:20702594 | | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SF3B4 mRNA | CTD | PMID:20188158 | | benzo[a]pyrene | decreases expression | ISO | RGD:1320131 | 6480464 | Benzo(a)pyrene results in decreased expression of SF3B4 protein | CTD | PMID:20097212 | | copper(2+) sulfate | increases expression | ISO | RGD:1320131 | 6480464 | Copper Sulfate results in increased expression of SF3B4 mRNA | CTD | PMID:19549813 | | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of SF3B4 mRNA | CTD | PMID:17361019 | | diethylstilbestrol | increases expression | ISO | RGD:1309667 | 6480464 | Diethylstilbestrol results in increased expression of SF3B4 mRNA | CTD | PMID:17011747 | | elemental selenium | increases expression | ISO | RGD:1320131 | 6480464 | Selenium results in increased expression of SF3B4 mRNA | CTD | PMID:19244175 | | ionomycin | multiple interactions | ISO | RGD:1320131 | 6480464 | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA; more ... | CTD | PMID:15477007 | | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SF3B4 mRNA | CTD | PMID:17562736 | | phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:1320131 | 6480464 | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA; more ... | CTD | PMID:15477007 | | quercetin | increases expression | ISO | RGD:1320131 | 6480464 | Quercetin results in increased expression of SF3B4 mRNA | CTD | PMID:21632981 | | selenium atom | increases expression | ISO | RGD:1320131 | 6480464 | Selenium results in increased expression of SF3B4 mRNA | CTD | PMID:19244175 | |
 Gene Ontology Annotations
Biological Process
| mRNA processing | | IEA | UniProtKB-KW:KW-0507 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 | | RNA splicing | | IEA | UniProtKB-KW:KW-0508 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 | |
| 1558843 | Ecla_m | epistatic circling A C57L/J 1 (mouse) | | | Not determined | | 3 | 65366294 | 99366439 | Mouse |
| 1301971 | Cia5_m | collagen induced arthritis QTL 5 (mouse) | | | Not determined | | 3 | 65943273 | 99943410 | Mouse |
| 4141669 | Vmmt18_m | vertebral morphology and mechanical traits 18 (mouse) | | | Not determined | | 3 | 68203118 | 102203263 | Mouse |
| 4142498 | Hctq1_m | hematocrit QTL 1 (mouse) | | | Not determined | | 3 | 68985423 | 102985534 | Mouse |
| 1357796 | Trmq5_m | T cell ratio modifier QTL 5 (mouse) | | | Not determined | | 3 | 70067069 | 104067190 | Mouse |
| 1301422 | Sle11_m | systematic lupus erythematosus susceptibility 11 (mouse) | | | Not determined | | 3 | 70105519 | 104105657 | Mouse |
| 1300595 | Tmevd2_m | Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse) | | | Not determined | | 3 | 75359917 | 109360164 | Mouse |
| 1301392 | Eae3_m | susceptibility to experimental allergic encephalomyelitis 3 (mouse) | | | Not determined | | 3 | 79445337 | 113445444 | Mouse |
| 4142423 | Prtia1_m | pristane induced arthritis 1 (mouse) | | | Not determined | | 3 | 79885628 | 113885768 | Mouse |
| 1357629 | Ssta5_m | susceptibility to Salmonella typhimurium antigens 5 (mouse) | | | Not determined | | 3 | 79885628 | 113885768 | Mouse |
| 1301277 | nctm1_m | Nakano cataract modifier 1 (mouse) | | | Not determined | | 3 | 80083059 | 114083208 | Mouse |
| 1301947 | Pcfm3_m | periosteal circumference and femur length 3 (mouse) | | | Not determined | | 3 | 80981259 | 114981404 | Mouse |
| 1301904 | Iba2_m | induction of brown adipocytes 2 (mouse) | | | Not determined | | 3 | 82043650 | 116043791 | Mouse |
| 1301862 | Tchol1_m | total cholesterol level 1 (mouse) | | | Not determined | | 3 | 83269519 | 117269667 | Mouse |
| 1302181 | Lvic2_m | liver iron content 2 (mouse) | | | Not determined | | 3 | 83269519 | 117269667 | Mouse |
| 1300752 | Ap6q_m | alcohol preference 6 QTL (mouse) | | | Not determined | | 3 | 83360598 | 117360744 | Mouse |
| 1301388 | Hdlq21_m | HDL QTL 21 (mouse) | | | Not determined | | 3 | 83360598 | 117360744 | Mouse |
| 1301272 | Cfsw1_m | cystic fibrosis survival to weaning 1 (mouse) | | | Not determined | | 3 | 83779519 | 117779651 | Mouse |
| 4142099 | Cq3_m | cholesterol QTL 3 (mouse) | | | Not determined | | 3 | 84785525 | 118785674 | Mouse |
| 4141455 | Bwq8_m | body weight QTL 8 (mouse) | | | Not determined | | 3 | 84785525 | 118785674 | Mouse |
| 4141747 | Tbqt4_m | tibia bone quality traits 4 (mouse) | | | Not determined | | 3 | 84827765 | 118827914 | Mouse |
| 4142178 | Ctrq2_m | C. trachomatis resistance QTL 2 (mouse) | | | Not determined | | 3 | 89036582 | 137410211 | Mouse |
| 1357489 | Trmq6_m | T cell ratio modifier QTL 6 (mouse) | | | Not determined | | 3 | 90272538 | 124272674 | Mouse |
| 1301349 | Pgia26_m | proteoglycan induced arthritis 26 (mouse) | | | Not determined | | 3 | 92147135 | 126147252 | Mouse |