Gene: Dok1 (docking protein 1)
Mus musculus
Symbol:
Dok1
Name:
docking protein 1
Description:
ENCODES a protein that exhibits receptor signaling protein activity; INVOLVED IN intracellular protein kinase cascade; Ras protein signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; PARTICIPATES IN insulin signaling pathway; platelet-derived growth factor signaling pathway; measles infection pathway; ASSOCIATED WITH abnormal bone marrow cell morphology/development; abnormal epididymal fat pad morphology; abnormal fat cell morphology; FOUND IN cytoplasm (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
AW557123; docking protein 1; downstream of tyrosine kinase 1; OTTMUSP00000027191; p62(dok); p62DOK
Orthologs:
Homo sapiens : DOK1
(docking protein 1, 62kDa (downstream of tyrosine kinase 1))
HGNC
Rattus norvegicus : Dok1
(docking protein 1)
Latest Assembly:
Mouse Genome Assembly Build 37
Position:
Map Chr Position Strand Source Mouse Genome Assembly GRCm38 6 83,030,934 - 83,033,471 - NCBI Mouse cM Map 6 35.94 NCBI Mouse Celera Assembly 6 85,012,444 - 85,014,981 - NCBI Mouse Genome Assembly Build 37 6 82,980,928 - 82,983,465 - NCBI Mouse Genome Assembly Build 36.1 6 82,980,928 - 82,983,459 - NCBI Mouse Cytogenetic Map 6 C3 NCBI
Model
Gene Ontology Annotations
Biological Process
intracellular protein kinase cascade IPI UniProtKB:P97797 2290270 MGI:MGI:1350556|PMID:10585470 MGI MGI:MGI:1350556 PMID:10585470 MAPK cascade TAS 2290270 MGI:MGI:2137764|PMID:11470823 MGI MGI:MGI:2137764 PMID:11470823 Ras protein signal transduction IPI UniProtKB:Q91YX7 2290270 MGI:MGI:892055|PMID:9008161 MGI MGI:MGI:892055 PMID:9008161 transmembrane receptor protein tyrosine kinase signaling pathway IPI UniProtKB:P07141 2290270 MGI:MGI:1350556|PMID:10585470 MGI MGI:MGI:1350556 PMID:10585470
1301589 Obq14_m obesity QTL 14 (mouse) Not determined 6 81943982 115944100 Mouse 1301320 Ots1_m ovarian teratoma susceptibility 1 (mouse) Not determined 6 79605945 113606143 Mouse 1357875 Pfat2_m predicted fat percentage 2 (mouse) Not determined 6 76413943 110414087 Mouse 4141376 Dbm1_m diabetes modifier 1 (mouse) Not determined 6 75666497 109666691 Mouse 1300954 Fcsa1_m femoral cross-sectional area 1 (mouse) Not determined 6 71931018 105931164 Mouse 1301521 Pas1c_m pulmonary adenoma susceptibility 1c (mouse) Not determined 6 71931018 105931164 Mouse 1558903 Salpa2_m serum alkaline phosphatase activity 2 (mouse) Not determined 6 71525054 105525172 Mouse 1300869 Stheal5_m soft tissue heal 5 (mouse) Not determined 6 71525054 105525172 Mouse 1301813 Skl3_m skeletal size (tail length) 3 (mouse) Not determined 6 70375892 104376028 Mouse 1301034 Egrm2_m early growth rate (mouse) Not determined 6 70375892 104376028 Mouse 1301254 Skts11_m skin tumor susceptibility 11 (mouse) Not determined 6 70375892 104376028 Mouse 1301962 Eila2_m ethanol induced locomotor activity 2 (mouse) Not determined 6 70375892 104376028 Mouse 1300782 Rear1_m rearing 1 (mouse) Not determined 6 70375892 104376028 Mouse 1301876 Bits2_m bitterness sensitivity 2 (mouse) Not determined 6 70375892 104376028 Mouse 1300711 Pbwg8_m postnatal body weight growth 8 (mouse) Not determined 6 69756799 103756921 Mouse 1300650 Bw18_m body weight QTL 18 (mouse) Not determined 6 66663863 100664025 Mouse 1300546 Ssta3_m susceptibility to Salmonella typhimurium antigens 3 (mouse) Not determined 6 66421193 100421316 Mouse 1301369 Im4_m immunoregulatory 4 (mouse) Not determined 6 63434732 97434899 Mouse 4141287 Bmd20_m bone mineral density 20 (mouse) Not determined 6 58494350 92494483 Mouse 1300556 Cia6_m collagen induced arthritis QTL 6 (mouse) Not determined 6 58397577 92397704 Mouse 1302131 Bmd8_m bone mineral density 8 (mouse) Not determined 6 52111712 116105285 Mouse