Gene: CCNT2 (cyclin T2)  Homo sapiens
Symbol: CCNT2
Name: cyclin T2
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cyclin T2a; cyclin T2b; cyclin-T2; cycT2; CYCT2; FLJ13583; FLJ90560; MGC134840; OTTHUMP00000162502; OTTHUMP00000162503; SDS-stable vimentin-bound DNA fragment HEF42VIM22; subunit of positive elongation transcription factor b
Orthologs: Mus musculus : Ccnt2 (cyclin T2)  MGI
Rattus norvegicus : Ccnt2 (cyclin T2)
Related Pseudogenes: CCNT2P1  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_12135,176,183 - 135,216,995+NCBI
Human Genome Assembly HuRef2127,668,086 - 127,708,608+NCBI
Human Genome Assembly GRCh372135,676,392 - 135,716,915+NCBI
Human Genome Assembly Build 362135,392,863 - 135,431,057+NCBI
Human Cytogenetic Map2q21.3 NCBI
Human Genome Assembly2135,510,124 - 135,548,316 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)

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References - curated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
  
More on CCNT2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
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Vista
Vista + UCSC

RGD Object Information
RGD ID: 1319417
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE



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