Gene: Prmt5 (protein arginine N-methyltransferase 5)  Mus musculus

Symbol: Prmt5
Name: protein arginine N-methyltransferase 5
Description: ENCODES a protein that exhibits chromatin binding; methyltransferase activity (ortholog); protein-arginine omega-N symmetric methyltransferase activity (ortholog); INVOLVED IN negative regulation of transcription from RNA polymerase II promoter; endothelial cell activation (ortholog); peptidyl-arginine methylation (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; p53 signaling pathway; ASSOCIATED WITH abnormal inner cell mass proliferation; complete embryonic lethality between implantation and somite formation; ASSOCIATED WITH Leydig Cell Tumor (ortholog); Seminoma (ortholog); FOUND IN nucleus; cytoplasm (ortholog); protein complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Jbp1; OTTMUSP00000021696; protein arginine N-methyltransferase 5; shk1 kinase-binding protein 1 homolog; Skb1; SKB1 homolog
Orthologs: Homo sapiens : PRMT5 (protein arginine methyltransferase 5)  HGNC
Rattus norvegicus : Prmt5 (protein arginine methyltransferase 5)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381454,507,182 - 54,517,470-NCBI
Mouse cM Map14 -NCBI
Mouse Celera Assembly1452,302,644 - 52,312,943-NCBI
Mouse Genome Assembly Build 371455,126,019 - 55,136,307-NCBI
Mouse Genome Assembly Build 36.11455,126,296 - 55,136,252-NCBI
Mouse Cytogenetic Map14 C1 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Prmt5
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
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RGD Object Information
RGD ID: 1319179
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2013-06-11
Status: ACTIVE