Gene: SCUBE1 (signal peptide, CUB domain, EGF-like 1)
Homo sapiens
Symbol:
SCUBE1
Name:
signal peptide, CUB domain, EGF-like 1
Description:
This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
OTTHUMP00000198230; signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide-CUB domain-EGF-related 1
Orthologs:
Mus musculus : Scube1
(signal peptide, CUB domain, EGF-like 1)
MGI
Scube1
(signal peptide, CUB domain, EGF-like 1)
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 22 27,515,181 - 27,655,617 - NCBI Human Genome Assembly HuRef 22 26,557,501 - 26,697,243 - NCBI Human Genome Assembly GRCh37 22 43,599,229 - 43,739,394 - NCBI Human Celera Assembly 22 27,509,622 - 27,649,802 - NCBI Human Genome Assembly Build 36 22 41,929,174 - 42,069,299 - NCBI Human Cytogenetic Map 22 q13 NCBI Human Genome Assembly 22 41,924,495 - 42,063,785 NCBI
Model
Gene Ontology Annotations
1300033 BP38_H Blood pressure QTL 38 (human) 2.07 Blood pressure hypertension susceptibility 22 21595686 47595686 Human 2292884 PRSTS36_H Prostate tumor susceptibility QTL 36 (human) Prostate tumor susceptibility early onsset 22 21595686 47595686 Human 2301166 PRSTS398_H Prostate tumor susceptibility QTL 398 (human) 2.21 Prostate tumor susceptibility 22 21595686 47595686 Human 2302769 MAMTS33_H Mammary tumor susceptibility QTL 33 (human) .046 Mammary tumor susceptibility 22 23274073 49274073 Human 1331647 COPD4_H Chronic obstructive pulmonary disease QTL 4 (human) 1.37 Chronic airflow obstruction FEV1 <80% predicted and FEV/FVC<90% predicted 22 23406771 49406771 Human 2292840 PRSTS91_H Prostate tumor susceptibility QTL 91 (human) Prostate tumor susceptibility 22 23750965 49750965 Human 2292844 PRSTS85_H Prostate tumor susceptibility QTL 85 (human) Prostate tumor susceptibility 22 23750965 49750965 Human 2302754 MAMTS30_H Mammary tumor susceptibility QTL 30 (human) .013 Mammary tumor susceptibility 22 24023322 50023322 Human 2303083 MAMTS47_H Mammary tumor susceptibility QTL 47 (human) 1.2 Mammary tumor susceptibility 22 29501409 45475610 Human 2289610 BW480_H Body weight QTL 480 (human) 1.4 Body weight lean mass 22 30540955 51238065 Human 1300031 BP55_H Blood pressure QTL 55 (human) 1.54 .00383 Blood pressure diastolic 22 32269254 51238065 Human 2292982 PRSTS144_H Prostate tumor susceptibility QTL 144 (human) 5.15 .000019 Prostate tumor susceptibility 22 32269254 51238065 Human 2302758 MAMTS5_H Mammary tumor susceptibility QTL 5 (human) .0003 Mammary tumor susceptibility 22 40419332 51238065 Human
Gene Ontology Annotations
