Gene: Htra2 (HtrA serine peptidase 2)  Mus musculus

Symbol: Htra2
Name: HtrA serine peptidase 2
Description: ENCODES a protein that exhibits peptidase activity (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN adult locomotory behavior; adult walking behavior; forebrain development; PARTICIPATES IN intrinsic apoptotic pathway; Parkinson disease pathway; ASSOCIATED WITH abnormal action potential; abnormal astrocyte morphology; abnormal basal ganglion morphology; ASSOCIATED WITH Huntington Disease; Infarction, Middle Cerebral Artery; Myocardial Reperfusion Injury; FOUND IN CD40 receptor complex; internal side of plasma membrane; mitochondrion; INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; cadmium dichloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI481710; high temperature requirement protein A2; mnd2; motor neuron degeneration 2; Omi; omi stress-regulated endoprotease; OTTMUSP00000025609; OTTMUSP00000025610; OTTMUSP00000025611; OTTMUSP00000025612; OTTMUSP00000025613; protease, serine, 25; Prss25; serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI
Orthologs: Homo sapiens : HTRA2 (HtrA serine peptidase 2)  HGNC
Rattus norvegicus : Htra2 (HtrA serine peptidase 2)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm38683,051,266 - 83,054,571-NCBI
Mouse cM Map635.94 NCBI
Mouse Celera Assembly685,033,853 - 85,037,160-NCBI
Mouse Genome Assembly Build 37683,001,260 - 83,004,565-NCBI
Mouse Genome Assembly Build 36.1683,001,276 - 83,004,565-NCBI
Mouse Cytogenetic Map6 C3 NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
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RGD Object Information
RGD ID: 1318944
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2013-02-27
Status: ACTIVE