USP34 (ubiquitin specific peptidase 34)

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General
Array IDs

Gene: USP34 (ubiquitin specific peptidase 34) Homo sapiens

Symbol:

USP34

Name:

ubiquitin specific peptidase 34

Description:

ENCODES a protein that exhibits cysteine-type endopeptidase activity; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; INVOLVED IN positive regulation of canonical Wnt receptor signaling pathway; protein K48-linked deubiquitination; INTERACTS WITH (-)-epigallocatechin 3-gallate; benzo[a]pyrene; formaldehyde

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

deubiquitinating enzyme 34; FLJ43910; KIAA0570; KIAA0729; MGC104459; OTTHUMP00000201402; ubiquitin carboxyl-terminal hydrolase 34; ubiquitin specific protease 34; ubiquitin thioesterase 34; ubiquitin thiolesterase 34; ubiquitin-specific-processing protease 34

Orthologs:

Rattus norvegicus : Usp34 (ubiquitin specific peptidase 34)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	61,280,123 - 61,532,046	-	NCBI
Human Genome Assembly HuRef	2	61,155,323 - 61,406,983	-	NCBI
Human Genome Assembly GRCh37	2	61,414,590 - 61,697,849	-	NCBI
Human Celera Assembly	2	61,259,053 - 61,542,286	-	NCBI
Human Genome Assembly Build 36	2	61,268,094 - 61,551,353	-	NCBI
Human Cytogenetic Map	2	p15		NCBI
Human Genome Assembly	2	61,326,887 - 61,544,591		NCBI

Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation (Toggle Detail/Summary View)

Gene-Chemical Interaction Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
(-)-epigallocatechin 3-gallate	multiple interactions	EXP		6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of USP34 mRNA	CTD	PMID:22079256
2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO		6480464	Tetrachlorodibenzodioxin affects the expression of USP34 mRNA	CTD	PMID:18691609
2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:1565181	6480464	Tetrachlorodibenzodioxin results in decreased expression of USP34 mRNA	CTD	PMID:21215274
2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO		6480464	Tetrachlorodibenzodioxin results in decreased expression of USP34 mRNA	CTD	PMID:19770486
3,4-methylenedioxymethamphetamine	decreases expression	ISO		6480464	N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of USP34 mRNA	CTD	PMID:20188158
aflatoxin B1	increases expression	ISO		6480464	Aflatoxin B1 results in increased expression of USP34 mRNA	CTD	PMID:19770486
benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of USP34 mRNA	CTD	PMID:20106945
benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of USP34 mRNA	CTD	PMID:20106945 PMID:21632981
benzo[a]pyrene	multiple interactions	ISO		6480464	[Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of USP34 mRNA	CTD	PMID:21715664
ciguatoxin CTX1B	affects expression	ISO		6480464	Ciguatoxins affects the expression of USP34 mRNA	CTD	PMID:18353800
formaldehyde	decreases expression	EXP		6480464	Formaldehyde results in decreased expression of USP34 mRNA	CTD	PMID:20655997
succimer	multiple interactions	ISO		6480464	[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of USP34 mRNA	CTD	PMID:21641980
testosterone enanthate	affects expression	EXP		6480464	testosterone enanthate affects the expression of USP34 mRNA	CTD	PMID:17440010
tunicamycin	decreases expression	ISO		6480464	Tunicamycin results in decreased expression of USP34 mRNA	CTD	PMID:17127020

Gene Ontology Annotations

Biological Process

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
positive regulation of canonical Wnt receptor signaling pathway		IDA		2290271	PMID:21383061	UniProtKB	PMID:21383061
protein K48-linked deubiquitination		IDA		2290271	PMID:21383061	UniProtKB	PMID:21383061
ubiquitin-dependent protein catabolic process		IEA	InterPro:IPR001394\|InterPro:IPR018200	2290271	GO_REF:0000002	InterPro	GO_REF:0000002
Wnt receptor signaling pathway		IEA	UniProtKB-KW:KW-0879	2290271	GO_REF:0000037	UniProtKB	GO_REF:0000037

Molecular Function

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
cysteine-type endopeptidase activity		IMP		2290271	PMID:21383061	UniProtKB	PMID:21383061
protein binding		IPI	UniProtKB:O15169	2290271	PMID:21383061	UniProtKB	PMID:21383061
protein binding		IPI	UniProtKB:Q9Y2T1	2290271	PMID:21383061	UniProtKB	PMID:21383061
ubiquitin thiolesterase activity		IDA		2290271	PMID:21383061	UniProtKB	PMID:21383061
ubiquitin-specific protease activity		IDA		2290271	PMID:21383061	UniProtKB	PMID:21383061

Gene-Chemical Interaction Annotations

	(-)-epigallocatechin 3-gallate (EXP)
	2,3,7,8-tetrachlorodibenzodioxine (ISO)
	3,4-methylenedioxymethamphetamine (ISO)
	aflatoxin B1 (ISO)

	benzo[a]pyrene (EXP,ISO)
	ciguatoxin CTX1B (ISO)
	formaldehyde (EXP)
	succimer (ISO)

	testosterone enanthate (EXP)
	tunicamycin (ISO)

Gene Ontology Annotations

Biological Process

	positive regulation of canonical Wnt receptor signaling pathway (IDA)
	protein K48-linked deubiquitination (IDA)
	ubiquitin-dependent protein catabolic process (IEA)

Wnt receptor signaling pathway (IEA)

Molecular Function

	cysteine-type endopeptidase activity (IMP)
	protein binding (IPI)

	ubiquitin thiolesterase activity (IDA)
	ubiquitin-specific protease activity (IDA)

References - curated

1.	RGD automated import pipeline for gene-chemical interactions

References - uncurated

PubMed	12168954
	12477932
	12838346
	14702039
	14715245
	15345747
	15489334
	17478428
	20379614
	21139048
	21383061
	21890473
	21906983
	22118674
	22412388
	22505724
	22586326
	22863883
	22939629
	9628581
	9872452

Genomics

Comparative Map Data

USP34 (Homo sapiens)

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	61,280,123 - 61,532,046	-	NCBI
Human Genome Assembly HuRef	2	61,155,323 - 61,406,983	-	NCBI
Human Genome Assembly GRCh37	2	61,414,590 - 61,697,849	-	NCBI
Human Celera Assembly	2	61,259,053 - 61,542,286	-	NCBI
Human Genome Assembly Build 36	2	61,268,094 - 61,551,353	-	NCBI
Human Cytogenetic Map	2	p15		NCBI
Human Genome Assembly	2	61,326,887 - 61,544,591		NCBI

Usp34 (Rattus norvegicus)

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	14	q22		NCBI
RGSC Genome Assembly v5.0	14	104,954,072 - 105,100,563	+	NCBI
RGSC Genome Assembly v3.4	14	103,990,220 - 104,426,186	+	NCBI
Rat Celera Assembly	14	96,263,246 - 96,453,075	+	NCBI

Position Markers

D2S337

Map	Chr	Position	Source
Human GeneMap99-G3 RH Map	2	2441.0	UniSTS
Human Whitehead-RH Map	2	259.8	UniSTS
Human GeneMap99-GB4 RH Map	2	189.82	UniSTS
Human Stanford-G3 RH Map	2	2484.0	UniSTS
Human deCODE Assembly Map	2	83.98	UniSTS
Human TNG Radiation Hybrid Map	2	39333.0	UniSTS
Human Genome Assembly HuRef	2	61,410,355 - 61,410,595	UniSTS
Human Genome Assembly GRCh37	2	61,669,931 - 61,670,171	UniSTS
Human Genome Assembly GRCh37	6	151,201,504 - 151,201,711	UniSTS
Human Celera Assembly	2	61,514,371 - 61,514,609	RGD
Human Celera Assembly	6	151,935,364 - 151,935,571	UniSTS
Human Genome Assembly Build 36	2	61,523,435 - 61,523,675	RGD
Genethon Human Genetic Map	2	84.1	UniSTS
Marshfield Human Genetic Map	2	80.69	RGD

SHGC-44477

Map	Chr	Position	Source
Human TNG Radiation Hybrid Map	2	34603.0	UniSTS
Human Genome Assembly HuRef	2	61,243,579 - 61,243,701	UniSTS
Human Genome Assembly GRCh37	2	61,502,880 - 61,503,002	UniSTS
Human Celera Assembly	2	61,347,336 - 61,347,458	RGD
Human Genome Assembly Build 36	2	61,356,384 - 61,356,506	RGD
Human Cytogenetic Map	2	p15	UniSTS

SGC31101

Map	Chr	Position	Source
Human Whitehead-RH Map	2	259.7	UniSTS
Human GeneMap99-GB4 RH Map	2	193.88	UniSTS
Human Genome Assembly HuRef	2	61,245,957 - 61,246,095	UniSTS
Human Genome Assembly GRCh37	2	61,505,258 - 61,505,396	UniSTS
Human Celera Assembly	2	61,349,714 - 61,349,852	RGD
Human Genome Assembly Build 36	2	61,358,762 - 61,358,900	RGD
Human Cytogenetic Map	2	p15	UniSTS

RH68443

Map	Chr	Position	Source
Human NCBI RH Map	2	349.4	UniSTS
Human GeneMap99-GB4 RH Map	2	193.88	UniSTS
Human Genome Assembly HuRef	2	61,386,285 - 61,386,426	UniSTS
Human Genome Assembly GRCh37	2	61,645,870 - 61,646,011	UniSTS
Human Celera Assembly	2	61,490,310 - 61,490,451	RGD
Human Genome Assembly Build 36	2	61,499,374 - 61,499,515	RGD
Human Cytogenetic Map	2	p15	UniSTS

RH16395

Map	Chr	Position	Source
Human NCBI RH Map	2	349.4	UniSTS
Human GeneMap99-GB4 RH Map	2	193.88	UniSTS
Human Genome Assembly HuRef	2	61,265,925 - 61,266,051	UniSTS
Human Genome Assembly GRCh37	2	61,525,225 - 61,525,351	UniSTS
Human Celera Assembly	2	61,369,682 - 61,369,808	RGD
Human Genome Assembly Build 36	2	61,378,729 - 61,378,855	RGD
Human Cytogenetic Map	2	p15	UniSTS

RH93011

Map	Chr	Position	Source
Human GeneMap99-GB4 RH Map	2	189.82	UniSTS
Human Genome Assembly HuRef	2	61,207,348 - 61,207,502	UniSTS
Human Genome Assembly GRCh37	2	61,466,645 - 61,466,799	UniSTS
Human Celera Assembly	2	61,311,104 - 61,311,258	RGD
Human Genome Assembly Build 36	2	61,320,149 - 61,320,303	RGD
Human Cytogenetic Map	2	p15	UniSTS

RH122613

Map	Chr	Position	Source
Human TNG Radiation Hybrid Map	2	34616.0	UniSTS
Human Genome Assembly HuRef	2	61,256,068 - 61,256,351	UniSTS
Human Genome Assembly GRCh37	2	61,515,368 - 61,515,651	UniSTS
Human Celera Assembly	2	61,359,825 - 61,360,108	RGD
Human Genome Assembly Build 36	2	61,368,872 - 61,369,155	RGD
Human Cytogenetic Map	2	p15	UniSTS

D1S2533

Map	Chr	Position	Source
Human Genome Assembly HuRef	2	61,155,371 - 61,155,454	UniSTS
Human Genome Assembly GRCh37	2	61,414,642 - 61,414,725	UniSTS
Human Celera Assembly	2	61,259,101 - 61,259,184	RGD
Human Genome Assembly Build 36	2	61,268,146 - 61,268,229	RGD
Human Cytogenetic Map	2	p15	UniSTS

SHGC-107752

Map	Chr	Position	Source
Human TNG Radiation Hybrid Map	2	34621.0	UniSTS
Human Genome Assembly HuRef	2	61,281,073 - 61,281,263	UniSTS
Human Genome Assembly GRCh37	2	61,540,450 - 61,540,640	UniSTS
Human Celera Assembly	2	61,384,922 - 61,385,112	RGD
Human Genome Assembly Build 36	2	61,393,954 - 61,394,144	RGD
Human Cytogenetic Map	2	p15	UniSTS

ECD12965

Map	Chr	Position	Source
Human Genome Assembly HuRef	21	19,624,965 - 19,625,495	UniSTS
Human Genome Assembly HuRef	2	61,384,403 - 61,384,927	UniSTS
Human Genome Assembly GRCh37	21	34,213,774 - 34,214,304	UniSTS
Human Genome Assembly GRCh37	2	61,643,988 - 61,644,512	UniSTS
Human Celera Assembly	21	19,399,352 - 19,399,882	UniSTS
Human Celera Assembly	2	61,488,428 - 61,488,952	RGD
Human Genome Assembly Build 36	2	61,497,492 - 61,498,016	RGD
Human Cytogenetic Map	2	p15	UniSTS

SHGC-34452

Map	Chr	Position	Source
Human Whitehead-RH Map	2	254.6	UniSTS
Human GeneMap99-GB4 RH Map	2	187.61	UniSTS
Human Genome Assembly HuRef	2	61,155,172 - 61,155,321	UniSTS
Human Genome Assembly GRCh37	2	61,414,439 - 61,414,588	UniSTS
Human Celera Assembly	2	61,258,902 - 61,259,051	RGD
Human Genome Assembly Build 36	2	61,267,943 - 61,268,092	RGD
Human Cytogenetic Map	2	p15	UniSTS

D2S2701

Map	Chr	Position	Source
Human Whitehead-YAC Contig Map	2		UniSTS
Human Whitehead-RH Map	2	256.8	UniSTS
Human GeneMap99-GB4 RH Map	2	189.92	UniSTS
Human Genome Assembly HuRef	2	61,155,342 - 61,155,544	UniSTS
Human Genome Assembly GRCh37	2	61,414,609 - 61,414,815	UniSTS
Human Celera Assembly	2	61,259,072 - 61,259,274	RGD
Human Genome Assembly Build 36	2	61,268,113 - 61,268,319	RGD
Human Cytogenetic Map	2	p15	UniSTS

RH68436

Map	Chr	Position	Source
Human NCBI RH Map	2	349.4	UniSTS
Human GeneMap99-GB4 RH Map	2	193.88	UniSTS
Human Genome Assembly HuRef	2	61,155,081 - 61,155,215	UniSTS
Human Genome Assembly GRCh37	2	61,414,348 - 61,414,482	UniSTS
Human Celera Assembly	2	61,258,811 - 61,258,945	RGD
Human Genome Assembly Build 36	2	61,267,852 - 61,267,986	RGD
Human Cytogenetic Map	2	p15	UniSTS

A009P16

Map	Chr	Position	Source
Human GeneMap99-GB4 RH Map	2	193.88	UniSTS
Human Genome Assembly HuRef	2	61,157,750 - 61,157,849	UniSTS
Human Genome Assembly GRCh37	2	61,417,021 - 61,417,120	UniSTS
Human Celera Assembly	2	61,261,477 - 61,261,576	RGD
Human Genome Assembly Build 36	2	61,270,525 - 61,270,624	RGD
Human Cytogenetic Map	2	p15	UniSTS

RH45777

Map	Chr	Position	Source
Human NCBI RH Map	2	349.4	UniSTS
Human GeneMap99-GB4 RH Map	2	193.88	UniSTS
Human Genome Assembly HuRef	2	61,158,862 - 61,159,037	UniSTS
Human Genome Assembly GRCh37	2	61,418,133 - 61,418,308	UniSTS
Human Celera Assembly	2	61,262,589 - 61,262,764	RGD
Human Genome Assembly Build 36	2	61,271,637 - 61,271,812	RGD
Human Cytogenetic Map	2	p15	UniSTS

RH45746

Map	Chr	Position	Source
Human NCBI RH Map	2	346.7	UniSTS
Human GeneMap99-GB4 RH Map	2	189.82	UniSTS
Human Genome Assembly HuRef	2	61,186,866 - 61,187,052	UniSTS
Human Genome Assembly GRCh37	2	61,446,136 - 61,446,322	UniSTS
Human Celera Assembly	2	61,290,600 - 61,290,786	RGD
Human Genome Assembly Build 36	2	61,299,640 - 61,299,826	RGD
Human Cytogenetic Map	2	p15	UniSTS

G32731

Map	Chr	Position	Source
Human Genome Assembly HuRef	2	61,157,750 - 61,157,849	UniSTS
Human Genome Assembly GRCh37	2	61,417,021 - 61,417,120	UniSTS
Human Celera Assembly	2	61,261,477 - 61,261,576	UniSTS
Human Cytogenetic Map	2	p15	UniSTS

RH68825

Map	Chr	Position	Strand	Source
Human GeneMap99-GB4 RH Map	2	190.02		UniSTS
Human Cytogenetic Map	2	p15		UniSTS

D2S337

Map	Chr	Position	Source
Human Whitehead-RH Map	2	259.8	UniSTS
Human deCODE Assembly Map	2	83.98	UniSTS
Human Cytogenetic Map	6	q25.1	UniSTS
Human Cytogenetic Map	2	p15	UniSTS
Genethon Human Genetic Map	2	84.1	UniSTS
Marshfield Human Genetic Map	2	80.69	UniSTS

QTLs in Region (Human Genome Assembly GRCh37)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357382	SLEP2_H	Serum leptin level QTL 2 (human)	4.95	.0000009	Hormone level	leptin	2	17491957	68239157	Human
2289624	BW483_H	Body weight QTL 483 (human)	3.3		Body fat amount	percent fat	2	36622327	62622327	Human
2289627	BW482_H	Body weight QTL 482 (human)	2.56		Body fat amount	none	2	49622186	68239157	Human
1559126	SCL53_H	Serum cholesterol level QTL 53 (human)	2.32		Lipid level	triglyceride	2	55239077	81239077	Human
2289322	BW372_H	Body weight QTL 372 (human)	1.88	.00164	Body fat amount	abdominal	2	55239077	81239077	Human
1558699	HRV2_H	Heart rate variability QTL 2 (human)	1.81		Heart rate variability	low-frequency power	2	59291776	208725006	Human
1578611	SCL132_H	Serum cholesterol level QTL 132 (human)	2		Lipid level	HDL cholesterol	2	60139274	86139274	Human
2289213	BW346_H	Body weight QTL 346 (human)		.003	Body fat amount	percent fat	2	60139274	86139274	Human

Sequence

Nucleotide Sequences

Nucleotide RefSeqs	NM_014709	(Get FASTA)	Search GEO for Microarray Profiles
GenBank Nucleotide	AB011142	(Get FASTA)	Search GEO for Microarray Profiles
	AB018272	(Get FASTA)	Search GEO for Microarray Profiles
	ABBA01075349	(Get FASTA)	Search GEO for Microarray Profiles
	ABBA01075350	(Get FASTA)	Search GEO for Microarray Profiles
	ABBA01075351	(Get FASTA)	Search GEO for Microarray Profiles
	ABBA01075352	(Get FASTA)	Search GEO for Microarray Profiles
	ABBA01075353	(Get FASTA)	Search GEO for Microarray Profiles
	AC016727	(Get FASTA)	Search GEO for Microarray Profiles
	AC016747	(Get FASTA)	Search GEO for Microarray Profiles
	AC016894	(Get FASTA)	Search GEO for Microarray Profiles
	AC018889	(Get FASTA)	Search GEO for Microarray Profiles
	AJ586138	(Get FASTA)	Search GEO for Microarray Profiles
	AK001193	(Get FASTA)	Search GEO for Microarray Profiles
	AK022637	(Get FASTA)	Search GEO for Microarray Profiles
	AK023171	(Get FASTA)	Search GEO for Microarray Profiles
	AK023845	(Get FASTA)	Search GEO for Microarray Profiles
	AK024341	(Get FASTA)	Search GEO for Microarray Profiles
	AK124932	(Get FASTA)	Search GEO for Microarray Profiles
	AK125898	(Get FASTA)	Search GEO for Microarray Profiles
	AK126741	(Get FASTA)	Search GEO for Microarray Profiles
	AL050092	(Get FASTA)	Search GEO for Microarray Profiles
	AL050376	(Get FASTA)	Search GEO for Microarray Profiles
	AL831918	(Get FASTA)	Search GEO for Microarray Profiles
	AMYH01010380	(Get FASTA)	Search GEO for Microarray Profiles
	AW293998	(Get FASTA)	Search GEO for Microarray Profiles
	BC022783	(Get FASTA)	Search GEO for Microarray Profiles
	BC062325	(Get FASTA)	Search GEO for Microarray Profiles
	BC107761	(Get FASTA)	Search GEO for Microarray Profiles
	BC141839	(Get FASTA)	Search GEO for Microarray Profiles
	BX473680	(Get FASTA)	Search GEO for Microarray Profiles
	CH471053	(Get FASTA)	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

NM_014709

RefSeq Status:

VALIDATED

Type:

CODING

Protein Acc Id:

NP_055524

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	61,280,123 - 61,532,046	-	NCBI
Human Genome Assembly HuRef	2	61,155,323 - 61,406,983	-	RGD
Human Genome Assembly GRCh37	2	61,414,590 - 61,697,849	-	RGD
Human Celera Assembly	2	61,259,053 - 61,542,286	-	RGD
Human Genome Assembly Build 36	2	61,268,094 - 61,551,353	-	NCBI Archive

Protein Sequences

Protein RefSeqs	NP_055524	(Get FASTA)
GenBank Protein	AAH22783	(Get FASTA)
	AAH62325	(Get FASTA)
	AAI07762	(Get FASTA)
	BAA25496	(Get FASTA)
	BAA34449	(Get FASTA)
	BAG54261	(Get FASTA)
	CAB43264	(Get FASTA)
	CAD38579	(Get FASTA)
	CAE51938	(Get FASTA)
	EAW99998	(Get FASTA)
	Q70CQ2	(Get FASTA)

Promoters

RGD ID:

6798417

Promoter ID:

HG_KWN:32801

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

HeLa_S3, K562, Lymphoblastoid

Transcripts:

OTTHUMT00000325835

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,270,411 - 61,270,952	-	MPROMDB

RGD ID:

6798414

Promoter ID:

HG_KWN:32802

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Lymphoblastoid, NB4

Transcripts:

OTTHUMT00000325758

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,271,311 - 61,272,822	-	MPROMDB

RGD ID:

6798416

Promoter ID:

HG_KWN:32803

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

K562, Lymphoblastoid

Transcripts:

OTTHUMT00000325834

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,274,426 - 61,274,926	-	MPROMDB

RGD ID:

6798415

Promoter ID:

HG_KWN:32815

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Jurkat, Lymphoblastoid

Transcripts:

OTTHUMT00000325825

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,346,781 - 61,347,281	-	MPROMDB

RGD ID:

6859962

Promoter ID:

EPDNEW_H3142

Type:

initiation region

Name:

USP34_7

Description:

ubiquitin specific peptidase 34

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,418,498 - 61,418,558		EPDNEW

RGD ID:

6859956

Promoter ID:

EPDNEW_H3143

Type:

initiation region

Name:

USP34_6

Description:

ubiquitin specific peptidase 34

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,441,762 - 61,441,822		EPDNEW

RGD ID:

6859958

Promoter ID:

EPDNEW_H3144

Type:

initiation region

Name:

USP34_5

Description:

ubiquitin specific peptidase 34

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,447,500 - 61,447,560		EPDNEW

RGD ID:

6859960

Promoter ID:

EPDNEW_H3145

Type:

initiation region

Name:

USP34_4

Description:

ubiquitin specific peptidase 34

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,449,776 - 61,449,836		EPDNEW

RGD ID:

6860018

Promoter ID:

EPDNEW_H3146

Type:

initiation region

Name:

USP34_3

Description:

ubiquitin specific peptidase 34

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,493,175 - 61,493,235		EPDNEW

RGD ID:

6859964

Promoter ID:

EPDNEW_H3147

Type:

initiation region

Name:

USP34_2

Description:

ubiquitin specific peptidase 34

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,508,305 - 61,508,365		EPDNEW

RGD ID:

6798420

Promoter ID:

HG_KWN:32823

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, Jurkat, K562, Lymphoblastoid, NB4

Transcripts:

OTTHUMT00000325650, OTTHUMT00000327075

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	2	61,551,206 - 61,552,117	-	MPROMDB

RGD ID:

6856200

Promoter ID:

EPDNEW_H1265

Type:

initiation region

Name:

RWDD3_1

Description:

RWD domain containing 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Human Genome Assembly Build 36	1	95,699,779 - 95,699,839		EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
COSMIC	USP34	COSMIC
Ensembl Genes	ENSG00000115464	ENTREZGENE
Ensembl Protein	ENSP00000381577	ENTREZGENE
Ensembl Transcript	ENST00000398571	ENTREZGENE
Entrez Gene	9736	ENTREZGENE
Germonline	ENSG00000115464
HGNC ID	20066	ENTREZGENE
HomoloGene Group ID	40978	ENTREZGENE
HPRD ID	11665	ENTREZGENE
InterPro	ARM-type_fold	UniProtKB/Swiss-Prot
	Pept_C19ubi-hydrolase_C_CS	UniProtKB/Swiss-Prot
	Peptidase_C19	UniProtKB/Swiss-Prot
IPI	IPI00297593	UniProtKB/Swiss-Prot
	IPI00787401	UniProtKB/Swiss-Prot
	IPI00894492	UniProtKB/Swiss-Prot
KEGG Report	hsa:9736	ENTREZGENE, UniProtKB/Swiss-Prot
Pfam	UCH	UniProtKB/Swiss-Prot
PharmGKB	PA134897042	PharmGKB
PROSITE	UCH_2_1	UniProtKB/Swiss-Prot
	UCH_2_2	UniProtKB/Swiss-Prot
	UCH_2_3	UniProtKB/Swiss-Prot
Superfamily-SCOP	ARM-type_fold	UniProtKB/Swiss-Prot
UniGene	Hs.644708	ENTREZGENE
UniProt	H7BZ73_HUMAN	UniProtKB/TrEMBL
	H7C150_HUMAN	UniProtKB/TrEMBL
	H7C183_HUMAN	UniProtKB/TrEMBL
	UBP34_HUMAN	UniProtKB/Swiss-Prot

More on USP34

Entrez Gene

Ensembl Gene

Genome Browser:

(hg18) (hg19)

RGD Object Information
RGD ID:	1318847
Created:	2005-01-12
Species:	Homo sapiens
Last Modified:	2013-03-05
Status:	ACTIVE