SLC30A8 (solute carrier family 30 (zinc transporter), member 8)

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Keyword

Gene: SLC30A8 (solute carrier family 30 (zinc transporter), member 8) Homo sapiens

Symbol:

SLC30A8

Name:

solute carrier family 30 (zinc transporter), member 8

Description:

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

OTTHUMP00000228049; OTTHUMP00000228051; OTTHUMP00000228052; zinc transporter 8; zinc transporter ZnT-8; ZnT-8; ZNT8

Orthologs:

Mus musculus : Slc30a8 (solute carrier family 30 (zinc transporter), member 8) MGI
Rattus norvegicus : Slc30a8 (solute carrier family 30 (zinc transporter), member 8)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	8	118,232,607 - 118,459,713	+	NCBI
Human Genome Assembly HuRef	8	113,288,921 - 113,515,635	+	NCBI
Human Genome Assembly GRCh37	8	117,962,512 - 118,188,953	+	NCBI
Human Genome Assembly Build 36	8	118,216,518 - 118,258,134	+	NCBI
Human Cytogenetic Map	8	q24.11		NCBI
Human Genome Assembly	8	118,216,747 - 118,254,101		NCBI