Gene: WBP11 (WW domain binding protein 11)
Homo sapiens
Symbol:
WBP11
Name:
WW domain binding protein 11
Description:
This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008]
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
DKFZp779M1063; Npw38-binding protein NpwBP; NPWBP; OTTHUMP00000239327; OTTHUMP00000239328; SH3 domain-binding protein SNP70; SIPP1; splicing factor that interacts with PQBP-1 and PP1; splicing factor, PQBP1 and PP1 interacting; WBP-11; WBP-11; WW domain-binding protein 11
Orthologs:
Mus musculus : Wbp11
(WW domain binding protein 11)
MGI
Wbp11
(WW domain binding protein 11)
Related Pseudogenes:
WBP11P1
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 12 14,808,152 - 14,825,141 - NCBI Human Genome Assembly HuRef 12 14,708,868 - 14,725,858 - NCBI Human Genome Assembly GRCh37 12 14,939,412 - 14,956,401 - NCBI Human Celera Assembly 12 20,084,400 - 20,101,388 - NCBI Human Genome Assembly Build 36 12 14,830,679 - 14,847,668 - NCBI Human Cytogenetic Map 12 p12.3 NCBI Human Genome Assembly 12 14,830,680 - 14,847,668 NCBI
Model
Gene Ontology Annotations
Biological Process mRNA processing IEA UniProtKB-KW:KW-0507 2290271 GO_REF:0000037 UniProtKB GO_REF:0000037 RNA processing IEA InterPro:IPR019007 2290271 GO_REF:0000002 InterPro GO_REF:0000002 RNA splicing IEA Ensembl:ENSMUSP00000112213 2290271 GO_REF:0000019 ENSEMBL GO_REF:0000019 rRNA processing IEA UniProtKB-KW:KW-0698 2290271 GO_REF:0000037 UniProtKB GO_REF:0000037
1298480 RA20_H Rheumatoid arthritis QTL 20 (human) .0031 Joint/bone inflammation rheumatoid arthritis 12 4015103 30015103 Human 1300028 BP53_H Blood pressure QTL 53 (human) 1.33 .00673 Blood pressure systolic 12 1 16587449 Human 1331663 COPD1_H Chronic obstructive pulmonary disease QTL 1 (human) 2.61 Chronic airflow obstruction FEV1 <80% predicted and FEV/FVC<90% predicted 12 13606455 20679893 Human 1331646 COPD21_H Chronic obstructive pulmonary disease QTL 21 (human) 2.43 Chronic airflow obstruction FEV1 12 13084357 21739503 Human 1358216 BW65_H Body weight QTL 65 (human) 2.2 Body fat amount fat mass before exercise training 12 5351170 47336847 Human 1559357 BW81_H Body weight QTL 81 (human) 1.89 .005 Body weight body mass index 10 1 21157708 Human 1559345 BW82_H Body weight QTL 82 (human) 1.83 .006 Body weight body mass index 12 1 21157708 Human 1559125 SPSL2_H Serum P-selectin level QTL 2 (human) 2.59 Serum P-selectin level 12 12450154 116082709 Human 1578622 SCL130_H Serum cholesterol level QTL 130 (human) 2.6 Lipid level HDL cholesterol 12 12449930 53197213 Human 1643086 BW160_H Body weight QTL 160 (human) .0226 Body weight BMI 12 4015103 30015103 Human 1643279 BW192_H Body weight QTL 192 (human) .0128 Body weight BMI 12 1 21157708 Human 2289481 BW252_H Body weight QTL 252 (human) 2.04 Body morphometry waist circumference 12 5973666 31973666 Human 2293480 PRSTS284_H Prostate tumor susceptibility QTL 284 (human) Prostate tumor susceptibility 12 1 16991805 Human 2293467 PRSTS304_H Prostate tumor susceptibility QTL 304 (human) .032 Prostate tumor susceptibility 12 1 16991805 Human 2299959 PRSTS329_H Prostate tumor susceptibility QTL 329 (human) 1.55 .0038 Prostate tumor susceptibility 12 1 16587449 Human 2300115 PRSTS336_H Prostate tumor susceptibility QTL 336 (human) Prostate tumor susceptibility 12 1 16587449 Human 2301155 PRSTS402_H Prostate tumor susceptibility QTL 402 (human) 1 Prostate tumor susceptibility 12 14647434 40647434 Human 2316878 GLUCO293_H Glucose level QTL 293 (human) 2.58 .001 Glucose level 12 5973666 31973666 Human 2316332 GLUCO228_H Glucose level QTL 228 (human) 1.99 .0012 Glucose level 12 14647434 40647434 Human 2316329 GLUCO229_H Glucose level QTL 229 (human) 1 .02 Glucose level 18 14647434 40647434 Human
Gene Ontology Annotations
