Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | Glod4 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of GLOD4 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | Glod4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GLOD4 mRNA | CTD | PMID:22206623 | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | decreases expression | EXP | | 6480464 | Metribolone results in decreased expression of GLOD4 protein | CTD | PMID:17152098 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Glod4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GLOD4 promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GLOD4 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Glod4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GLOD4 mRNA | CTD | PMID:21570461 and PMID:24680724 | 3-chloropropane-1,2-diol | increases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of GLOD4 mRNA | CTD | PMID:28522335 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GLOD4 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GLOD4 mRNA | CTD | PMID:28628672 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of GLOD4 mRNA | CTD | PMID:15498508 | amphotericin B | decreases expression | EXP | | 6480464 | Amphotericin B results in decreased expression of GLOD4 mRNA | CTD | PMID:20849824 | aristolochic acid A | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of GLOD4 protein | CTD | PMID:33212167 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Soot co-treated with Benzo(a)pyrene] results in increased expression of GLOD4 protein modified form | CTD | PMID:24464499 | benzo[e]pyrene | increases methylation | EXP | | 6480464 | benzo(e)pyrene results in increased methylation of GLOD4 intron | CTD | PMID:30157460 | bisphenol A | multiple interactions | ISO | Glod4 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of GLOD4 mRNA | CTD | PMID:26496021 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GLOD4 protein | CTD | PMID:37567409 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of GLOD4 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of GLOD4 mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | ISO | Glod4 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of GLOD4 gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of GLOD4 mRNA | CTD | PMID:25181051 | Brodifacoum | increases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | bromfenacoum results in increased expression of GLOD4 protein | CTD | PMID:28903499 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of GLOD4 mRNA | CTD | PMID:20849824 | cyclophosphamide | decreases expression | EXP | | 6480464 | Cyclophosphamide results in decreased expression of GLOD4 mRNA | CTD | PMID:20849824 | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GLOD4 mRNA | CTD | PMID:28628672 | dibutyl phthalate | decreases expression | ISO | Glod4 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of GLOD4 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | EXP | | 6480464 | dicrotophos results in decreased expression of GLOD4 mRNA | CTD | PMID:28302478 | disodium selenite | increases expression | EXP | | 6480464 | Sodium Selenite results in increased expression of GLOD4 mRNA | CTD | PMID:18175754 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of GLOD4 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of GLOD4 mRNA | CTD | PMID:29391264 | enzyme inhibitor | multiple interactions | EXP | | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of GLOD4 protein | CTD | PMID:23301498 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of GLOD4 protein | CTD | PMID:20621659 | fenvalerate | increases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of GLOD4 protein | CTD | PMID:33656234 | folic acid | multiple interactions | ISO | Glod4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GLOD4 mRNA | CTD | PMID:22206623 | folpet | increases expression | ISO | Glod4 (Mus musculus) | 6480464 | folpet results in increased expression of GLOD4 mRNA | CTD | PMID:31558096 | fulvestrant | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of GLOD4 gene | CTD | PMID:31601247 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of GLOD4 mRNA | CTD | PMID:20849824 | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GLOD4 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of GLOD4 protein | CTD | PMID:32959892 | lead diacetate | increases expression | ISO | Glod4 (Mus musculus) | 6480464 | lead acetate results in increased expression of GLOD4 mRNA | CTD | PMID:21829687 | methapyrilene | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of GLOD4 mRNA | CTD | PMID:30467583 | methapyrilene | increases methylation | EXP | | 6480464 | Methapyrilene results in increased methylation of GLOD4 intron | CTD | PMID:30157460 | paracetamol | affects expression | ISO | Glod4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of GLOD4 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of GLOD4 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of GLOD4 mRNA | CTD | PMID:25704631 | perfluorododecanoic acid | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | perfluorododecanoic acid results in decreased expression of GLOD4 protein | CTD | PMID:19854247 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | Glod4 (Mus musculus) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of GLOD4 protein | CTD | PMID:26178269 | perfluorooctanoic acid | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | perfluorooctanoic acid results in decreased expression of GLOD4 mRNA | CTD | PMID:19162173 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of GLOD4 protein | CTD | PMID:26879310 | SB 431542 | multiple interactions | EXP | | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of GLOD4 protein | CTD | PMID:37664457 | silver atom | decreases expression | ISO | Glod4 (Mus musculus) | 6480464 | Silver results in decreased expression of GLOD4 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Glod4 (Mus musculus) | 6480464 | Silver results in decreased expression of GLOD4 mRNA | CTD | PMID:27131904 | sodium arsenite | affects expression | EXP | | 6480464 | sodium arsenite affects the expression of GLOD4 mRNA | CTD | PMID:29319823 | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of GLOD4 mRNA | CTD | PMID:31533062 | tamibarotene | affects expression | EXP | | 6480464 | tamibarotene affects the expression of GLOD4 mRNA | CTD | PMID:15498508 | tert-butyl hydroperoxide | increases expression | ISO | Glod4 (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in increased expression of GLOD4 mRNA | CTD | PMID:15003993 | testosterone | multiple interactions | ISO | Glod4 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of GLOD4 mRNA | CTD | PMID:26496021 | thioacetamide | decreases expression | ISO | Glod4 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of GLOD4 mRNA | CTD | PMID:34492290 | triptonide | decreases expression | ISO | Glod4 (Mus musculus) | 6480464 | triptonide results in decreased expression of GLOD4 mRNA | CTD | PMID:33045310 | |