Gene: SRCRB4D (scavenger receptor cysteine rich domain containing, group B (4 domains))
Homo sapiens
Symbol:
SRCRB4D
Name:
scavenger receptor cysteine rich domain containing, group B (4 domains)
Description:
The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.[supplied by OMIM, Apr 2004]
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
OTTHUMP00000161135; S4-SRCRB; S4D-SRCRB; scavenger receptor cysteine-rich domain-containing group B protein; scavenger receptor cysteine-rich protein SRCRB-S4D; SRCRB-S4D; SSC4D
Orthologs:
Mus musculus : Srcrb4d
(scavenger receptor cysteine rich domain containing, group B (4 domains))
MGI
Srcrb4d
(scavenger receptor cysteine rich domain containing, group B (4 domains))
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 7 79,326,161 - 79,346,547 - NCBI Human Alternate Assembly CRA_TCAGchr7v2 7 75,351,710 - 75,372,076 - NCBI Human Genome Assembly HuRef 7 71,105,136 - 71,125,320 - NCBI Human Genome Assembly GRCh37 7 76,018,646 - 76,039,012 - NCBI Human Celera Assembly 7 70,887,164 - 70,907,528 - NCBI Human Genome Assembly Build 36 7 75,856,582 - 75,876,948 - NCBI Human Cytogenetic Map 7 q11.23 NCBI Human Genome Assembly 7 75,663,296 - 75,683,663 NCBI
Model
Gene Ontology Annotations
Cellular Component extracellular region IEA UniProtKB-SubCell:SL-0243 2290271 GO_REF:0000039 UniProtKB GO_REF:0000039 membrane IEA InterPro:IPR001190|InterPro:IPR017448 2290271 GO_REF:0000002 InterPro GO_REF:0000002
1559392 SCL108_H Serum cholesterol level QTL 108 (human) 2.05 Lipid level triglyceride 7 42029608 96333512 Human 1581533 BP66_H Blood pressure QTL 66 (human) 3.1 .001 Blood pressure pulse pressure 7 55552490 81552490 Human 2314711 GLUCO67_H Glucose level QTL 67(human) 3.01 .018 Glucose level insulin sensitivity 7 55552490 81552490 Human 2314725 GLUCO63_H Glucose level QTL 63 (human) 2.11 .165 Glucose level insulin sensitivity 7 55552490 81552490 Human 2292938 PRSTS149_H Prostate tumor susceptibility QTL 149 (human) 5.66 .000083 Prostate tumor susceptibility 7 64872583 90872583 Human 2316718 GLUCO274_H Glucose level QTL 274 (human) 1.68 .00479 Glucose level 7 64872583 90872583 Human 1643547 GLUCO25_H Glucose level QTL 25 (human) .011 Glucose level non-insulin-dependent 7 65127036 91127036 Human 2314722 INSUL16_H Insulin level QTL 16 (human) 1.77 .127 Insulin level 7 65127036 91127036 Human 2301153 PRSTS390_H Prostate tumor susceptibility QTL 390 (human) 1.96 Prostate tumor susceptibility 7 65127036 91127036 Human 2301183 PRSTS380_H Prostate tumor susceptibility QTL 380 (human) Prostate tumor susceptibility 7 69796886 95796886 Human 1578608 SCL133_H Serum cholesterol level QTL 133 (human) 2.3 Lipid level total cholesterol 7 70789500 96789500 Human 1643388 BW321_H Body weight QTL 321 (human) 2.59 .0003 Body fat amount 7 70789500 96789500 Human 1643401 BMD1_H Bone mineral density QTL 1 (human) 2.59 .0003 Bone mineral density 7 70789500 96789500 Human 1558708 SCL5_H Serum cholesterol level QTL 5 (human) 1.6 Lipid level HDL cholesterol 7 71842345 96333512 Human 1559402 SCL110_H Serum cholesterol level QTL 110 (human) 1.67 Lipid level HDL cholesterol 7 71842345 112037629 Human
Gene Ontology Annotations
