BRPF3 (bromodomain and PHD finger containing 3) - Rat Genome Database

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Gene: BRPF3 (bromodomain and PHD finger containing 3) Homo sapiens
Analyze
Symbol: BRPF3
Name: bromodomain and PHD finger containing 3
RGD ID: 1315730
HGNC Page HGNC:14256
Description: Contributes to histone acetyltransferase activity. Involved in positive regulation of DNA replication. Located in nucleus. Part of MOZ/MORF histone acetyltransferase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bromodomain and PHD finger containing, 3; bromodomain and PHD finger-containing protein 3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38636,196,744 - 36,232,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl636,196,744 - 36,232,790 (+)EnsemblGRCh38hg38GRCh38
GRCh37636,164,521 - 36,200,567 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,272,528 - 36,308,545 (+)NCBINCBI36Build 36hg18NCBI36
Build 34636,272,527 - 36,308,541NCBI
Celera637,719,088 - 37,755,105 (+)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef635,884,145 - 35,920,113 (+)NCBIHuRef
CHM1_1636,166,317 - 36,202,330 (+)NCBICHM1_1
T2T-CHM13v2.0636,017,037 - 36,053,081 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Autism  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:6457647   PMID:10574462   PMID:12477932   PMID:14574404   PMID:14630798   PMID:16387653   PMID:17474147   PMID:18794358   PMID:19322201   PMID:21873635   PMID:24981860   PMID:25593309  
PMID:26496610   PMID:26620551   PMID:27270040   PMID:28514442   PMID:28533407   PMID:29507755   PMID:30021884   PMID:31753913   PMID:32296183   PMID:32694731   PMID:32911434   PMID:33961781  
PMID:34079125   PMID:35013218   PMID:35271311   PMID:36724073  


Genomics

Comparative Map Data
BRPF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38636,196,744 - 36,232,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl636,196,744 - 36,232,790 (+)EnsemblGRCh38hg38GRCh38
GRCh37636,164,521 - 36,200,567 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,272,528 - 36,308,545 (+)NCBINCBI36Build 36hg18NCBI36
Build 34636,272,527 - 36,308,541NCBI
Celera637,719,088 - 37,755,105 (+)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef635,884,145 - 35,920,113 (+)NCBIHuRef
CHM1_1636,166,317 - 36,202,330 (+)NCBICHM1_1
T2T-CHM13v2.0636,017,037 - 36,053,081 (+)NCBIT2T-CHM13v2.0
Brpf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,020,088 - 29,057,763 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1729,020,064 - 29,058,923 (+)EnsemblGRCm39 Ensembl
GRCm381728,801,126 - 28,838,789 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,801,090 - 28,839,949 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,938,071 - 28,975,734 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361728,528,715 - 28,566,378 (+)NCBIMGSCv36mm8
Celera1729,360,452 - 29,393,360 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.03NCBI
Brpf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8206,866,378 - 6,904,456 (+)NCBIGRCr8
mRatBN7.2206,864,684 - 6,902,760 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl206,865,985 - 6,902,690 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx207,582,306 - 7,612,192 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0206,944,161 - 6,974,050 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,425,707 - 7,455,600 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,047,800 - 6,086,099 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,049,286 - 6,086,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0208,301,702 - 8,339,497 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,090,877 - 7,121,564 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,086,214 - 7,122,618 (+)NCBI
Celera208,424,988 - 8,454,924 (+)NCBICelera
Cytogenetic Map20p12NCBI
Brpf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554373,951,160 - 3,985,338 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554373,951,160 - 3,985,133 (+)NCBIChiLan1.0ChiLan1.0
BRPF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2550,661,710 - 50,697,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1646,531,510 - 46,567,433 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0635,755,305 - 35,791,304 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1636,956,841 - 36,992,113 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl636,959,709 - 36,989,933 (+)Ensemblpanpan1.1panPan2
BRPF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,315,228 - 5,346,328 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,310,617 - 5,350,055 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,331,493 - 5,366,230 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,659,469 - 5,694,224 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,662,630 - 5,694,224 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,314,136 - 5,348,838 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,393,160 - 5,427,851 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,493,161 - 5,527,895 (+)NCBIUU_Cfam_GSD_1.0
Brpf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494640,802,400 - 40,833,409 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647623,126,607 - 23,157,876 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647623,126,821 - 23,157,838 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRPF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl731,926,308 - 31,966,001 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1731,926,313 - 31,966,006 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2736,856,521 - 36,865,837 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BRPF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11735,891,139 - 35,926,621 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1735,891,141 - 35,923,084 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604436,151,210 - 36,186,729 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brpf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475421,431,574 - 21,462,051 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475421,431,574 - 21,466,158 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BRPF3
51 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_015695.2(BRPF3):c.1934C>T (p.Ser645Phe) single nucleotide variant Malignant melanoma [RCV000067331] Chr6:36210283 [GRCh38]
Chr6:36178060 [GRCh37]
Chr6:36286038 [NCBI36]
Chr6:6p21.31		 not provided
NM_015695.2(BRPF3):c.747C>T (p.Ile249=) single nucleotide variant Malignant melanoma [RCV000061417] Chr6:36201069 [GRCh38]
Chr6:36168846 [GRCh37]
Chr6:36276824 [NCBI36]
Chr6:6p21.31		 not provided
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_015695.3(BRPF3):c.2521A>C (p.Thr841Pro) single nucleotide variant Inborn genetic diseases [RCV003279448] Chr6:36213918 [GRCh38]
Chr6:36181695 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3149G>A (p.Gly1050Asp) single nucleotide variant Inborn genetic diseases [RCV003251275] Chr6:36222233 [GRCh38]
Chr6:36190010 [GRCh37]
Chr6:6p21.31		 uncertain significance
GRCh37/hg19 6p21.31-21.2(chr6:34683518-36905281)x3 copy number gain not provided [RCV000682660] Chr6:34683518..36905281 [GRCh37]
Chr6:6p21.31-21.2		 likely pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_015695.3(BRPF3):c.1685del (p.Ala562fs) deletion not provided [RCV003314112] Chr6:36207392 [GRCh38]
Chr6:36175169 [GRCh37]
Chr6:6p21.31		 uncertain significance
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1		 pathogenic
NM_015695.3(BRPF3):c.1978C>T (p.Leu660Phe) single nucleotide variant Autism [RCV003313343] Chr6:36210327 [GRCh38]
Chr6:36178104 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2077G>A (p.Ala693Thr) single nucleotide variant Inborn genetic diseases [RCV003249533] Chr6:36210426 [GRCh38]
Chr6:36178203 [GRCh37]
Chr6:6p21.31		 uncertain significance
GRCh37/hg19 6p21.31-21.2(chr6:34401304-38435497) copy number loss Severe intrauterine growth retardation [RCV001291973] Chr6:34401304..38435497 [GRCh37]
Chr6:6p21.31-21.2		 pathogenic
NC_000006.11:g.(?_30695893)_(36953949_?)dup duplication Proteasome-associated autoinflammatory syndrome 1 [RCV003113679] Chr6:30695893..36953949 [GRCh37]
Chr6:6p21.33-21.2		 uncertain significance
NM_015695.3(BRPF3):c.847A>G (p.Ser283Gly) single nucleotide variant Inborn genetic diseases [RCV003287357] Chr6:36201169 [GRCh38]
Chr6:36168946 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3520A>G (p.Ser1174Gly) single nucleotide variant Inborn genetic diseases [RCV002968605] Chr6:36230511 [GRCh38]
Chr6:36198288 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2882C>A (p.Ala961Asp) single nucleotide variant Inborn genetic diseases [RCV002753924] Chr6:36214279 [GRCh38]
Chr6:36182056 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2432C>G (p.Ala811Gly) single nucleotide variant Inborn genetic diseases [RCV002968637] Chr6:36211510 [GRCh38]
Chr6:36179287 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3344C>T (p.Pro1115Leu) single nucleotide variant Inborn genetic diseases [RCV002794175] Chr6:36228966 [GRCh38]
Chr6:36196743 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2908C>T (p.Arg970Cys) single nucleotide variant Inborn genetic diseases [RCV002773982] Chr6:36214305 [GRCh38]
Chr6:36182082 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2749G>A (p.Gly917Ser) single nucleotide variant Inborn genetic diseases [RCV002754375] Chr6:36214146 [GRCh38]
Chr6:36181923 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.599G>A (p.Arg200His) single nucleotide variant Inborn genetic diseases [RCV002685184] Chr6:36200921 [GRCh38]
Chr6:36168698 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.294A>T (p.Lys98Asn) single nucleotide variant Inborn genetic diseases [RCV002973975] Chr6:36200616 [GRCh38]
Chr6:36168393 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3019G>A (p.Glu1007Lys) single nucleotide variant Inborn genetic diseases [RCV002682734] Chr6:36217946 [GRCh38]
Chr6:36185723 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1643A>T (p.Glu548Val) single nucleotide variant Inborn genetic diseases [RCV002799699] Chr6:36207350 [GRCh38]
Chr6:36175127 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3280A>G (p.Ile1094Val) single nucleotide variant Inborn genetic diseases [RCV002759244] Chr6:36228902 [GRCh38]
Chr6:36196679 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2953G>A (p.Glu985Lys) single nucleotide variant Inborn genetic diseases [RCV002737900] Chr6:36214350 [GRCh38]
Chr6:36182127 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1105A>T (p.Ser369Cys) single nucleotide variant Inborn genetic diseases [RCV002798165] Chr6:36201427 [GRCh38]
Chr6:36169204 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2504C>T (p.Pro835Leu) single nucleotide variant Inborn genetic diseases [RCV002998606] Chr6:36213901 [GRCh38]
Chr6:36181678 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.677G>A (p.Ser226Asn) single nucleotide variant Inborn genetic diseases [RCV002703978] Chr6:36200999 [GRCh38]
Chr6:36168776 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1552C>G (p.Pro518Ala) single nucleotide variant Inborn genetic diseases [RCV002821666] Chr6:36204761 [GRCh38]
Chr6:36172538 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3563T>G (p.Ile1188Ser) single nucleotide variant Inborn genetic diseases [RCV002915115] Chr6:36230554 [GRCh38]
Chr6:36198331 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2555C>T (p.Ser852Phe) single nucleotide variant Inborn genetic diseases [RCV002697391] Chr6:36213952 [GRCh38]
Chr6:36181729 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.454G>A (p.Val152Ile) single nucleotide variant Inborn genetic diseases [RCV002803169] Chr6:36200776 [GRCh38]
Chr6:36168553 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3172A>G (p.Asn1058Asp) single nucleotide variant Inborn genetic diseases [RCV002892300] Chr6:36222256 [GRCh38]
Chr6:36190033 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1154C>A (p.Ala385Asp) single nucleotide variant Inborn genetic diseases [RCV002718270] Chr6:36201476 [GRCh38]
Chr6:36169253 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1402C>A (p.Pro468Thr) single nucleotide variant Inborn genetic diseases [RCV002768819] Chr6:36201724 [GRCh38]
Chr6:36169501 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3158G>A (p.Gly1053Glu) single nucleotide variant Inborn genetic diseases [RCV002897553] Chr6:36222242 [GRCh38]
Chr6:36190019 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1345A>C (p.Lys449Gln) single nucleotide variant Inborn genetic diseases [RCV002832031] Chr6:36201667 [GRCh38]
Chr6:36169444 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2059G>A (p.Gly687Arg) single nucleotide variant Inborn genetic diseases [RCV002809706] Chr6:36210408 [GRCh38]
Chr6:36178185 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.821A>G (p.Asn274Ser) single nucleotide variant Inborn genetic diseases [RCV002719849] Chr6:36201143 [GRCh38]
Chr6:36168920 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.506A>G (p.Glu169Gly) single nucleotide variant Inborn genetic diseases [RCV002668528] Chr6:36200828 [GRCh38]
Chr6:36168605 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3286G>A (p.Asp1096Asn) single nucleotide variant Inborn genetic diseases [RCV002835964] Chr6:36228908 [GRCh38]
Chr6:36196685 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.736G>A (p.Val246Ile) single nucleotide variant Inborn genetic diseases [RCV002935602] Chr6:36201058 [GRCh38]
Chr6:36168835 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3173A>G (p.Asn1058Ser) single nucleotide variant Inborn genetic diseases [RCV002896430] Chr6:36222257 [GRCh38]
Chr6:36190034 [GRCh37]
Chr6:6p21.31		 likely benign
NC_000006.11:g.(?_32148920)_(36953949_?)dup duplication not provided [RCV003154914] Chr6:32148920..36953949 [GRCh37]
Chr6:6p21.32-21.2		 uncertain significance
NM_015695.3(BRPF3):c.2838G>T (p.Arg946Ser) single nucleotide variant Inborn genetic diseases [RCV003197079] Chr6:36214235 [GRCh38]
Chr6:36182012 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.3484G>A (p.Val1162Met) single nucleotide variant Inborn genetic diseases [RCV003198171] Chr6:36230475 [GRCh38]
Chr6:36198252 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.562G>A (p.Val188Ile) single nucleotide variant Inborn genetic diseases [RCV003173726] Chr6:36200884 [GRCh38]
Chr6:36168661 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2327A>G (p.Asn776Ser) single nucleotide variant Inborn genetic diseases [RCV003198695] Chr6:36211405 [GRCh38]
Chr6:36179182 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1922G>A (p.Arg641Gln) single nucleotide variant Inborn genetic diseases [RCV003204158] Chr6:36210271 [GRCh38]
Chr6:36178048 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.1414C>T (p.Pro472Ser) single nucleotide variant Inborn genetic diseases [RCV003265316] Chr6:36201736 [GRCh38]
Chr6:36169513 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.152G>A (p.Arg51His) single nucleotide variant Inborn genetic diseases [RCV003285953] Chr6:36200474 [GRCh38]
Chr6:36168251 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2560C>A (p.Pro854Thr) single nucleotide variant Inborn genetic diseases [RCV003357649] Chr6:36213957 [GRCh38]
Chr6:36181734 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2990G>C (p.Gly997Ala) single nucleotide variant Inborn genetic diseases [RCV003366898] Chr6:36217917 [GRCh38]
Chr6:36185694 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.26G>A (p.Arg9Gln) single nucleotide variant Inborn genetic diseases [RCV003356326] Chr6:36200348 [GRCh38]
Chr6:36168125 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.955G>A (p.Ala319Thr) single nucleotide variant Inborn genetic diseases [RCV003352409] Chr6:36201277 [GRCh38]
Chr6:36169054 [GRCh37]
Chr6:6p21.31		 uncertain significance
NM_015695.3(BRPF3):c.2362C>T (p.Pro788Ser) single nucleotide variant Inborn genetic diseases [RCV003354742] Chr6:36211440 [GRCh38]
Chr6:36179217 [GRCh37]
Chr6:6p21.31		 uncertain significance
GRCh37/hg19 6p21.31-21.1(chr6:35562152-42003452)x1 copy number loss not provided [RCV003485510] Chr6:35562152..42003452 [GRCh37]
Chr6:6p21.31-21.1		 pathogenic
NM_015695.3(BRPF3):c.3055A>G (p.Ser1019Gly) single nucleotide variant not provided [RCV003457468] Chr6:36217982 [GRCh38]
Chr6:36185759 [GRCh37]
Chr6:6p21.31		 likely benign
NM_015695.3(BRPF3):c.3253C>G (p.Arg1085Gly) single nucleotide variant not provided [RCV003457469] Chr6:36225338 [GRCh38]
Chr6:36193115 [GRCh37]
Chr6:6p21.31		 uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR155hsa-miR-155-5pMirtarbaseexternal_infoProteomics//Western blotFunctional MTI17668390
MIR155hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)17588946
MIR155hsa-miR-155-5pMirtarbaseexternal_infoProteomics;OtherFunctional MTI (Weak)16675453

Predicted Target Of
Summary Value
Count of predictions:13646
Count of miRNA genes:1133
Interacting mature miRNAs:1426
Transcripts:ENST00000339717, ENST00000357641, ENST00000441123, ENST00000441730, ENST00000443324, ENST00000446974, ENST00000449261, ENST00000454960, ENST00000527657, ENST00000532330, ENST00000532538, ENST00000534400, ENST00000534694, ENST00000543502
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-16533  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37636,180,136 - 36,180,278UniSTSGRCh37
Build 36636,288,114 - 36,288,256RGDNCBI36
Celera637,734,674 - 37,734,816RGD
Cytogenetic Map6p21UniSTS
HuRef635,899,683 - 35,899,825UniSTS
Stanford-G3 RH Map62014.0UniSTS
NCBI RH Map6548.8UniSTS
GeneMap99-G3 RH Map62146.0UniSTS
RH46861  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37636,180,136 - 36,180,324UniSTSGRCh37
Build 36636,288,114 - 36,288,302RGDNCBI36
Celera637,734,674 - 37,734,862RGD
Cytogenetic Map6p21UniSTS
HuRef635,899,683 - 35,899,871UniSTS
GeneMap99-GB4 RH Map6137.56UniSTS
STS-N66794  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37636,200,298 - 36,200,419UniSTSGRCh37
Build 36636,308,276 - 36,308,397RGDNCBI36
Celera637,754,836 - 37,754,957RGD
Cytogenetic Map6p21UniSTS
HuRef635,919,844 - 35,919,965UniSTS
GeneMap99-GB4 RH Map6131.53UniSTS
BRPF3_4470  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37636,199,863 - 36,200,594UniSTSGRCh37
Build 36636,307,841 - 36,308,572RGDNCBI36
Celera637,754,401 - 37,755,132RGD
HuRef635,919,409 - 35,920,140UniSTS
D1S3695  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map15q23UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map6p21UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map1p34-p12UniSTS
Cytogenetic Map6q27UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2299 1548 1432 342 1006 195 3853 1414 2272 311 1410 1562 159 1073 2428 3
Low 138 1432 294 282 939 269 503 778 1460 106 43 49 14 1 131 360 1 2
Below cutoff 1 8 5 1 2 2 2 7 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_015695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002956276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_926148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_926149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB033112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK000751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK074362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z84485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000339717   ⟹   ENSP00000345419
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,196,966 - 36,232,590 (+)Ensembl
RefSeq Acc Id: ENST00000357641   ⟹   ENSP00000350267
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,196,744 - 36,232,790 (+)Ensembl
RefSeq Acc Id: ENST00000441123   ⟹   ENSP00000411558
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,200,406 - 36,232,790 (+)Ensembl
RefSeq Acc Id: ENST00000441730   ⟹   ENSP00000413022
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,211,448 - 36,232,787 (+)Ensembl
RefSeq Acc Id: ENST00000446974   ⟹   ENSP00000410669
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,197,396 - 36,200,608 (+)Ensembl
RefSeq Acc Id: ENST00000449261   ⟹   ENSP00000416842
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,196,966 - 36,232,590 (+)Ensembl
RefSeq Acc Id: ENST00000454960   ⟹   ENSP00000413655
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,197,452 - 36,200,709 (+)Ensembl
RefSeq Acc Id: ENST00000527657   ⟹   ENSP00000431894
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,204,414 - 36,207,348 (+)Ensembl
RefSeq Acc Id: ENST00000532330   ⟹   ENSP00000437087
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,200,297 - 36,231,317 (+)Ensembl
RefSeq Acc Id: ENST00000532538
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,211,201 - 36,214,066 (+)Ensembl
RefSeq Acc Id: ENST00000534400   ⟹   ENSP00000436504
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,200,297 - 36,231,317 (+)Ensembl
RefSeq Acc Id: ENST00000534694   ⟹   ENSP00000434501
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl636,196,966 - 36,232,590 (+)Ensembl
RefSeq Acc Id: NM_015695   ⟹   NP_056510
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,196,744 - 36,232,790 (+)NCBI
GRCh37636,164,408 - 36,200,567 (+)NCBI
Build 36636,272,528 - 36,308,545 (+)NCBI Archive
Celera637,719,088 - 37,755,105 (+)RGD
HuRef635,884,145 - 35,920,113 (+)RGD
CHM1_1636,166,317 - 36,202,330 (+)NCBI
T2T-CHM13v2.0636,017,037 - 36,053,081 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011514490   ⟹   XP_011512792
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,197,385 - 36,232,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011514491   ⟹   XP_011512793
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,197,385 - 36,232,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011514492   ⟹   XP_011512794
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,197,385 - 36,214,066 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047418649   ⟹   XP_047274605
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,197,385 - 36,232,790 (+)NCBI
RefSeq Acc Id: XM_047418650   ⟹   XP_047274606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,197,385 - 36,232,790 (+)NCBI
RefSeq Acc Id: XM_047418651   ⟹   XP_047274607
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,197,385 - 36,210,528 (+)NCBI
RefSeq Acc Id: XM_054355175   ⟹   XP_054211150
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0636,017,615 - 36,053,081 (+)NCBI
RefSeq Acc Id: XM_054355176   ⟹   XP_054211151
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0636,017,651 - 36,053,081 (+)NCBI
RefSeq Acc Id: XM_054355177   ⟹   XP_054211152
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0636,017,660 - 36,053,081 (+)NCBI
RefSeq Acc Id: XM_054355178   ⟹   XP_054211153
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0636,017,660 - 36,053,081 (+)NCBI
RefSeq Acc Id: XM_054355179   ⟹   XP_054211154
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0636,017,660 - 36,034,359 (+)NCBI
RefSeq Acc Id: XM_054355180   ⟹   XP_054211155
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0636,017,660 - 36,030,821 (+)NCBI
Protein Sequences
Protein RefSeqs NP_056510 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512792 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512793 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512794 (Get FASTA)   NCBI Sequence Viewer  
  XP_047274605 (Get FASTA)   NCBI Sequence Viewer  
  XP_047274606 (Get FASTA)   NCBI Sequence Viewer  
  XP_047274607 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211150 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211151 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211152 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211153 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211154 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211155 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH33652 (Get FASTA)   NCBI Sequence Viewer  
  AAI17388 (Get FASTA)   NCBI Sequence Viewer  
  AAI43918 (Get FASTA)   NCBI Sequence Viewer  
  AAI43919 (Get FASTA)   NCBI Sequence Viewer  
  BAA86600 (Get FASTA)   NCBI Sequence Viewer  
  BAA91359 (Get FASTA)   NCBI Sequence Viewer  
  BAB85060 (Get FASTA)   NCBI Sequence Viewer  
  EAX03877 (Get FASTA)   NCBI Sequence Viewer  
  EAX03878 (Get FASTA)   NCBI Sequence Viewer  
  EAX03879 (Get FASTA)   NCBI Sequence Viewer  
  EAX03880 (Get FASTA)   NCBI Sequence Viewer  
  EAX03881 (Get FASTA)   NCBI Sequence Viewer  
  EAX03882 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000345419.7
  ENSP00000350267
  ENSP00000350267.6
  ENSP00000410669.1
  ENSP00000411558.1
  ENSP00000413022.2
  ENSP00000413655.1
  ENSP00000416842.2
  ENSP00000431894.1
  ENSP00000434501.1
  ENSP00000436504
  ENSP00000436504.1
  ENSP00000437087
  ENSP00000437087.1
GenBank Protein Q9ULD4 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_056510   ⟸   NM_015695
- UniProtKB: Q17RB6 (UniProtKB/Swiss-Prot),   E7EX85 (UniProtKB/Swiss-Prot),   B7ZLN5 (UniProtKB/Swiss-Prot),   A6NJE2 (UniProtKB/Swiss-Prot),   A6ND56 (UniProtKB/Swiss-Prot),   Q5R3K8 (UniProtKB/Swiss-Prot),   Q9ULD4 (UniProtKB/Swiss-Prot),   E9PI60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512793   ⟸   XM_011514491
- Peptide Label: isoform X2
- UniProtKB: E9PI60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512792   ⟸   XM_011514490
- Peptide Label: isoform X1
- UniProtKB: E9PI60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512794   ⟸   XM_011514492
- Peptide Label: isoform X4
- UniProtKB: E9PSF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000437087   ⟸   ENST00000532330
RefSeq Acc Id: ENSP00000413655   ⟸   ENST00000454960
RefSeq Acc Id: ENSP00000413022   ⟸   ENST00000441730
RefSeq Acc Id: ENSP00000434501   ⟸   ENST00000534694
RefSeq Acc Id: ENSP00000436504   ⟸   ENST00000534400
RefSeq Acc Id: ENSP00000411558   ⟸   ENST00000441123
RefSeq Acc Id: ENSP00000345419   ⟸   ENST00000339717
RefSeq Acc Id: ENSP00000410669   ⟸   ENST00000446974
RefSeq Acc Id: ENSP00000416842   ⟸   ENST00000449261
RefSeq Acc Id: ENSP00000431894   ⟸   ENST00000527657
RefSeq Acc Id: ENSP00000350267   ⟸   ENST00000357641
RefSeq Acc Id: XP_047274605   ⟸   XM_047418649
- Peptide Label: isoform X6
- UniProtKB: Q9ULD4 (UniProtKB/Swiss-Prot),   Q17RB6 (UniProtKB/Swiss-Prot),   E7EX85 (UniProtKB/Swiss-Prot),   B7ZLN5 (UniProtKB/Swiss-Prot),   A6NJE2 (UniProtKB/Swiss-Prot),   A6ND56 (UniProtKB/Swiss-Prot),   Q5R3K8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_047274606   ⟸   XM_047418650
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047274607   ⟸   XM_047418651
- Peptide Label: isoform X5
- UniProtKB: F6XDC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054211150   ⟸   XM_054355175
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054211151   ⟸   XM_054355176
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054211152   ⟸   XM_054355177
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054211153   ⟸   XM_054355178
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054211154   ⟸   XM_054355179
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054211155   ⟸   XM_054355180
- Peptide Label: isoform X5
- UniProtKB: F6XDC4 (UniProtKB/TrEMBL)
Protein Domains
Bromo   Enhancer of polycomb-like N-terminal   PHD-type   PWWP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ULD4-F1-model_v2 AlphaFold Q9ULD4 1-1205 view protein structure

Promoters
RGD ID:6873002
Promoter ID:EPDNEW_H9666
Type:initiation region
Name:BRPF3_1
Description:bromodomain and PHD finger containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9667  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,196,773 - 36,196,833EPDNEW
RGD ID:6873004
Promoter ID:EPDNEW_H9667
Type:initiation region
Name:BRPF3_2
Description:bromodomain and PHD finger containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9666  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38636,197,340 - 36,197,400EPDNEW
RGD ID:6803811
Promoter ID:HG_KWN:53352
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_015695,   OTTHUMT00000318492,   OTTHUMT00000318495,   OTTHUMT00000318496
Position:
Human AssemblyChrPosition (strand)Source
Build 36636,272,221 - 36,273,102 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14256 AgrOrtholog
COSMIC BRPF3 COSMIC
Ensembl Genes ENSG00000096070 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000339717.11 UniProtKB/Swiss-Prot
  ENST00000357641 ENTREZGENE
  ENST00000357641.10 UniProtKB/Swiss-Prot
  ENST00000441123.1 UniProtKB/TrEMBL
  ENST00000441730.2 UniProtKB/TrEMBL
  ENST00000446974.1 UniProtKB/TrEMBL
  ENST00000449261.6 UniProtKB/TrEMBL
  ENST00000454960.1 UniProtKB/TrEMBL
  ENST00000527657.1 UniProtKB/TrEMBL
  ENST00000532330 ENTREZGENE
  ENST00000532330.5 UniProtKB/TrEMBL
  ENST00000534400 ENTREZGENE
  ENST00000534400.5 UniProtKB/TrEMBL
  ENST00000534694.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.920.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.30.140 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000096070 GTEx
HGNC ID HGNC:14256 ENTREZGENE
Human Proteome Map BRPF3 Human Proteome Map
InterPro Bromodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRPF3_ePHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Enhancer_polycomb-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP_dom UniProtKB/Swiss-Prot
  Zinc_finger_PHD-type_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:27154 UniProtKB/Swiss-Prot
NCBI Gene 27154 ENTREZGENE
OMIM 616856 OMIM
PANTHER BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD FINGER PROTEINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot
  zf-HC5HC2H_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA25425 PharmGKB
PRINTS BROMODOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot
  ZF_PHD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BROMO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/Swiss-Prot
UniProt A6ND56 ENTREZGENE
  A6NJE2 ENTREZGENE
  A8WI61_HUMAN UniProtKB/TrEMBL
  A8WI62_HUMAN UniProtKB/TrEMBL
  B7ZLN5 ENTREZGENE
  BRPF3_HUMAN UniProtKB/Swiss-Prot
  E7EX85 ENTREZGENE
  E9PI60 ENTREZGENE, UniProtKB/TrEMBL
  E9PJ12_HUMAN UniProtKB/TrEMBL
  E9PSF3 ENTREZGENE, UniProtKB/TrEMBL
  F6XDC4 ENTREZGENE, UniProtKB/TrEMBL
  H0Y7B4_HUMAN UniProtKB/TrEMBL
  H0Y7I6_HUMAN UniProtKB/TrEMBL
  Q17RB6 ENTREZGENE
  Q5R3K8 ENTREZGENE
  Q8N4T7_HUMAN UniProtKB/TrEMBL
  Q9ULD4 ENTREZGENE
UniProt Secondary A6ND56 UniProtKB/Swiss-Prot
  A6NJE2 UniProtKB/Swiss-Prot
  B7ZLN5 UniProtKB/Swiss-Prot
  E7EX85 UniProtKB/Swiss-Prot
  Q17RB6 UniProtKB/Swiss-Prot
  Q5R3K8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-17 BRPF3  bromodomain and PHD finger containing 3    bromodomain and PHD finger containing, 3  Symbol and/or name change 5135510 APPROVED