KIF3B (kinesin family member 3B) - Rat Genome Database

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Gene: KIF3B (kinesin family member 3B) Homo sapiens
Analyze
Symbol: KIF3B
Name: kinesin family member 3B
RGD ID: 1315643
HGNC Page HGNC:6320
Description: Enables small GTPase binding activity. Involved in cilium organization; mitotic spindle assembly; and opsin transport. Located in microtubule cytoskeleton. Part of kinesin II complex. Implicated in retinitis pigmentosa 89.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: FLA8; HH0048; KIAA0359; kinesin-like protein KIF3B; KLP-11; microtubule plus end-directed kinesin motor 3B; RP89
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382032,277,651 - 32,335,011 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2032,277,651 - 32,335,011 (+)EnsemblGRCh38hg38GRCh38
GRCh372030,865,454 - 30,922,814 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362030,329,128 - 30,386,475 (+)NCBINCBI36Build 36hg18NCBI36
Build 342030,329,127 - 30,386,470NCBI
Celera2027,621,777 - 27,678,845 (+)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2027,653,055 - 27,711,242 (+)NCBIHuRef
CHM1_12030,769,227 - 30,827,250 (+)NCBICHM1_1
T2T-CHM13v2.02034,001,508 - 34,059,883 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Temporal and spatial expression of KIF3B after acute spinal cord injury in adult rats. Yu X, etal., J Mol Neurosci. 2013 Feb;49(2):387-94. doi: 10.1007/s12031-012-9901-7. Epub 2012 Oct 24.
Additional References at PubMed
PMID:7559760   PMID:9205841   PMID:9427749   PMID:9506951   PMID:9733766   PMID:9865700   PMID:10395937   PMID:10548469   PMID:11780052   PMID:11912492   PMID:12477932   PMID:12821668  
PMID:12832475   PMID:15231748   PMID:15345558   PMID:16298999   PMID:16344560   PMID:16751776   PMID:17008358   PMID:17825299   PMID:18957512   PMID:19056867   PMID:19339549   PMID:19635168  
PMID:19664597   PMID:19940036   PMID:19946888   PMID:21244100   PMID:21832049   PMID:21871436   PMID:21873635   PMID:21988832   PMID:22145905   PMID:22658674   PMID:23376485   PMID:24368420  
PMID:25588831   PMID:25921289   PMID:26496610   PMID:27173435   PMID:28161539   PMID:28514442   PMID:28761002   PMID:29395067   PMID:29507755   PMID:30021884   PMID:30217970   PMID:30480076  
PMID:30720171   PMID:31091453   PMID:31157987   PMID:31746486   PMID:31773695   PMID:31932471   PMID:32237034   PMID:32386558   PMID:33153390   PMID:33961781   PMID:34857952   PMID:34918036  
PMID:35256949   PMID:35271311   PMID:35509820   PMID:35831314   PMID:35944360   PMID:36215168   PMID:36543142   PMID:37120454  


Genomics

Comparative Map Data
KIF3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382032,277,651 - 32,335,011 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2032,277,651 - 32,335,011 (+)EnsemblGRCh38hg38GRCh38
GRCh372030,865,454 - 30,922,814 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362030,329,128 - 30,386,475 (+)NCBINCBI36Build 36hg18NCBI36
Build 342030,329,127 - 30,386,470NCBI
Celera2027,621,777 - 27,678,845 (+)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2027,653,055 - 27,711,242 (+)NCBIHuRef
CHM1_12030,769,227 - 30,827,250 (+)NCBICHM1_1
T2T-CHM13v2.02034,001,508 - 34,059,883 (+)NCBIT2T-CHM13v2.0
Kif3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392153,132,028 - 153,175,310 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2153,133,333 - 153,175,310 (+)EnsemblGRCm39 Ensembl
GRCm382153,291,395 - 153,333,390 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2153,291,413 - 153,333,390 (+)EnsemblGRCm38mm10GRCm38
MGSCv372153,117,152 - 153,159,126 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,982,870 - 153,023,655 (+)NCBIMGSCv36mm8
Celera2159,118,383 - 159,173,625 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.41NCBI
Kif3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83162,218,621 - 162,258,191 (+)NCBIGRCr8
mRatBN7.23141,758,466 - 141,798,012 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3141,758,466 - 141,797,963 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3145,660,861 - 145,700,355 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03154,244,665 - 154,284,156 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,985,380 - 152,024,806 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03148,772,937 - 148,813,342 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,773,259 - 148,813,293 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03155,284,567 - 155,324,361 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,642,175 - 143,681,902 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13143,547,821 - 143,587,573 (+)NCBI
Celera3140,504,639 - 140,544,329 (+)NCBICelera
Cytogenetic Map3q41NCBI
Kif3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542228,738,572 - 28,780,112 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542228,738,567 - 28,779,584 (-)NCBIChiLan1.0ChiLan1.0
KIF3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,969,880 - 38,026,975 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12037,962,979 - 38,020,074 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02028,566,710 - 28,605,550 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12029,727,021 - 29,750,223 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2029,727,021 - 29,750,218 (+)Ensemblpanpan1.1panPan2
KIF3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12421,661,730 - 21,706,839 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2421,661,059 - 21,802,815 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2421,309,537 - 21,354,399 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02422,350,430 - 22,395,357 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2422,350,378 - 22,395,357 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12421,628,854 - 21,659,087 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02421,734,375 - 21,779,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02422,165,013 - 22,210,036 (+)NCBIUU_Cfam_GSD_1.0
Kif3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640170,749,389 - 170,764,166 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648519,180,571 - 19,198,429 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648519,180,751 - 19,198,321 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1735,914,246 - 35,961,522 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11735,914,214 - 35,962,332 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KIF3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1236,655,957 - 36,711,292 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl236,687,168 - 36,711,925 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605090,198,770 - 90,255,540 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624741270,834 - 314,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KIF3B
26 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 20q11.21(chr20:31289875-32302312)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052792]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052792]|See cases [RCV000052792] Chr20:31289875..32302312 [GRCh38]
Chr20:29877678..30890115 [GRCh37]
Chr20:29341339..30353776 [NCBI36]
Chr20:20q11.21		 uncertain significance
GRCh38/hg38 20p12.2-q12(chr20:9811433-39316956)x3 copy number gain See cases [RCV000052999] Chr20:9811433..39316956 [GRCh38]
Chr20:9792081..37945599 [GRCh37]
Chr20:9740081..37379013 [NCBI36]
Chr20:20p12.2-q12		 pathogenic
NM_004798.3(KIF3B):c.34G>A (p.Val12Met) single nucleotide variant Malignant melanoma [RCV000072574] Chr20:32309811 [GRCh38]
Chr20:30897614 [GRCh37]
Chr20:30361275 [NCBI36]
Chr20:20q11.21		 not provided
GRCh38/hg38 20q11.21(chr20:31254983-32575288)x3 copy number gain See cases [RCV000134504] Chr20:31254983..32575288 [GRCh38]
Chr20:29842786..31163090 [GRCh37]
Chr20:29306447..30626751 [NCBI36]
Chr20:20q11.21		 pathogenic
GRCh38/hg38 20q11.21(chr20:31254983-33473080)x3 copy number gain See cases [RCV000135358] Chr20:31254983..33473080 [GRCh38]
Chr20:29842786..32060886 [GRCh37]
Chr20:29306447..31524547 [NCBI36]
Chr20:20q11.21		 pathogenic
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3 copy number gain See cases [RCV000135859] Chr20:99557..64277321 [GRCh38]
Chr20:80198..62908674 [GRCh37]
Chr20:28198..62379118 [NCBI36]
Chr20:20p13-q13.33		 pathogenic
GRCh38/hg38 20q11.21-11.23(chr20:32062768-35906606)x3 copy number gain See cases [RCV000141833] Chr20:32062768..35906606 [GRCh38]
Chr20:30650571..34494528 [GRCh37]
Chr20:30114232..33957942 [NCBI36]
Chr20:20q11.21-11.23		 pathogenic
GRCh37/hg19 20p12.1-q11.21(chr20:17705775-31600738)x3 copy number gain See cases [RCV000240436] Chr20:17705775..31600738 [GRCh37]
Chr20:20p12.1-q11.21		 pathogenic
GRCh37/hg19 20p11.21-q11.21(chr20:24162775-31820857)x3 copy number gain See cases [RCV000448977] Chr20:24162775..31820857 [GRCh37]
Chr20:20p11.21-q11.21		 likely pathogenic
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555)x3 copy number gain See cases [RCV000510832] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_004798.4(KIF3B):c.146C>T (p.Thr49Met) single nucleotide variant Inborn genetic diseases [RCV003254667] Chr20:32309923 [GRCh38]
Chr20:30897726 [GRCh37]
Chr20:20q11.21		 uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555) copy number gain See cases [RCV000512450] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
Single allele duplication not provided [RCV000677978] Chr20:17705775..31600738 [GRCh37]
Chr20:20p12.1-q11.21		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62948788)x3 copy number gain not provided [RCV000741058] Chr20:63244..62948788 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62961294)x3 copy number gain not provided [RCV000741059] Chr20:63244..62961294 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62912463)x3 copy number gain not provided [RCV000741057] Chr20:63244..62912463 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_004798.4(KIF3B):c.1413G>A (p.Glu471=) single nucleotide variant not provided [RCV000948042] Chr20:32316226 [GRCh38]
Chr20:30904029 [GRCh37]
Chr20:20q11.21		 benign
NC_000020.10:g.(?_30795725)_(31395729_?)dup duplication Centromeric instability of chromosomes 1,9 and 16 and immunodeficiency [RCV001032627] Chr20:30795725..31395729 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.160C>T (p.Pro54Ser) single nucleotide variant Inborn genetic diseases [RCV003248575] Chr20:32309937 [GRCh38]
Chr20:30897740 [GRCh37]
Chr20:20q11.21		 uncertain significance
GRCh37/hg19 20q11.21-11.23(chr20:29833608-35087952)x3 copy number gain not provided [RCV000849735] Chr20:29833608..35087952 [GRCh37]
Chr20:20q11.21-11.23		 pathogenic
NM_004798.4(KIF3B):c.748G>C (p.Glu250Gln) single nucleotide variant Retinitis pigmentosa 89 [RCV001249562] Chr20:32310525 [GRCh38]
Chr20:30898328 [GRCh37]
Chr20:20q11.21		 pathogenic
NM_004798.4(KIF3B):c.2225G>A (p.Arg742Gln) single nucleotide variant Inborn genetic diseases [RCV003273662] Chr20:32331300 [GRCh38]
Chr20:30919103 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.2224C>T (p.Arg742Trp) single nucleotide variant Inborn genetic diseases [RCV003290799] Chr20:32331299 [GRCh38]
Chr20:30919102 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.1568T>C (p.Leu523Pro) single nucleotide variant Retinitis pigmentosa 89 [RCV001249563] Chr20:32316588 [GRCh38]
Chr20:30904391 [GRCh37]
Chr20:20q11.21		 pathogenic
NM_004798.4(KIF3B):c.1032A>T (p.Pro344=) single nucleotide variant Oligospermia [RCV001255222] Chr20:32310809 [GRCh38]
Chr20:30898612 [GRCh37]
Chr20:20q11.21		 association
NC_000020.10:g.(?_30795725)_(31395729_?)dup duplication Centromeric instability of chromosomes 1,9 and 16 and immunodeficiency [RCV001300701] Chr20:30795725..31395729 [GRCh37]
Chr20:20q11.21		 uncertain significance
GRCh37/hg19 20p11.21-q11.22(chr20:25442597-33761550) copy number gain not specified [RCV002052709] Chr20:25442597..33761550 [GRCh37]
Chr20:20p11.21-q11.22		 pathogenic
GRCh37/hg19 20p11.23-q11.22(chr20:18665879-33903216)x3 copy number gain not provided [RCV001829151] Chr20:18665879..33903216 [GRCh37]
Chr20:20p11.23-q11.22		 likely pathogenic
GRCh37/hg19 20p11.21-q11.21(chr20:24162775-31820857) copy number gain not specified [RCV002052707] Chr20:24162775..31820857 [GRCh37]
Chr20:20p11.21-q11.21		 likely pathogenic
NM_004798.4(KIF3B):c.1565A>G (p.Glu522Gly) single nucleotide variant not provided [RCV001954850] Chr20:32316585 [GRCh38]
Chr20:30904388 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.57G>C (p.Met19Ile) single nucleotide variant Inborn genetic diseases [RCV003261139] Chr20:32309834 [GRCh38]
Chr20:30897637 [GRCh37]
Chr20:20q11.21		 uncertain significance
GRCh37/hg19 20q11.21-11.23(chr20:29833535-34815537)x3 copy number gain not provided [RCV002474532] Chr20:29833535..34815537 [GRCh37]
Chr20:20q11.21-11.23		 likely pathogenic
NM_004798.4(KIF3B):c.2017A>G (p.Arg673Gly) single nucleotide variant Inborn genetic diseases [RCV002685128] Chr20:32330189 [GRCh38]
Chr20:30917992 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.679G>A (p.Glu227Lys) single nucleotide variant Inborn genetic diseases [RCV002774412] Chr20:32310456 [GRCh38]
Chr20:30898259 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.1319T>G (p.Met440Arg) single nucleotide variant Inborn genetic diseases [RCV002841469] Chr20:32311096 [GRCh38]
Chr20:30898899 [GRCh37]
Chr20:20q11.21		 uncertain significance
GRCh37/hg19 20q11.21-11.23(chr20:29652122-35603726)x3 copy number gain not provided [RCV002475651] Chr20:29652122..35603726 [GRCh37]
Chr20:20q11.21-11.23		 likely pathogenic
NM_004798.4(KIF3B):c.1222G>A (p.Asp408Asn) single nucleotide variant Inborn genetic diseases [RCV002844935] Chr20:32310999 [GRCh38]
Chr20:30898802 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.329G>A (p.Arg110His) single nucleotide variant Inborn genetic diseases [RCV002739822] Chr20:32310106 [GRCh38]
Chr20:30897909 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.49C>T (p.Arg17Trp) single nucleotide variant Inborn genetic diseases [RCV002916323] Chr20:32309826 [GRCh38]
Chr20:30897629 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.818C>T (p.Ser273Phe) single nucleotide variant Inborn genetic diseases [RCV002836419] Chr20:32310595 [GRCh38]
Chr20:30898398 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.898C>A (p.Leu300Ile) single nucleotide variant Inborn genetic diseases [RCV003280641] Chr20:32310675 [GRCh38]
Chr20:30898478 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.2144C>T (p.Ala715Val) single nucleotide variant Inborn genetic diseases [RCV003309651] Chr20:32330316 [GRCh38]
Chr20:30918119 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.1481del (p.Gln494fs) deletion Retinitis pigmentosa 89 [RCV003326223] Chr20:32316294 [GRCh38]
Chr20:30904097 [GRCh37]
Chr20:20q11.21		 likely benign
NM_004798.4(KIF3B):c.1849A>T (p.Ile617Leu) single nucleotide variant Inborn genetic diseases [RCV003347427] Chr20:32326871 [GRCh38]
Chr20:30914674 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.622A>G (p.Met208Val) single nucleotide variant KIF3B-related condition [RCV003405804] Chr20:32310399 [GRCh38]
Chr20:30898202 [GRCh37]
Chr20:20q11.21		 uncertain significance
GRCh37/hg19 20q11.21(chr20:29917837-31886619)x3 copy number gain not specified [RCV003986134] Chr20:29917837..31886619 [GRCh37]
Chr20:20q11.21		 uncertain significance
NM_004798.4(KIF3B):c.1245G>A (p.Arg415=) single nucleotide variant KIF3B-related condition [RCV003984620] Chr20:32311022 [GRCh38]
Chr20:30898825 [GRCh37]
Chr20:20q11.21		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1965
Count of miRNA genes:932
Interacting mature miRNAs:1105
Transcripts:ENST00000375712, ENST00000418717
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D20S555E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372030,922,566 - 30,922,667UniSTSGRCh37
Build 362030,386,227 - 30,386,328RGDNCBI36
Celera2027,678,597 - 27,678,698RGD
Cytogenetic Map20q11.21UniSTS
HuRef2027,710,994 - 27,711,095UniSTS
GeneMap99-GB4 RH Map20177.14UniSTS
NCBI RH Map20279.4UniSTS
SHGC-81319  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372030,920,638 - 30,920,949UniSTSGRCh37
Build 362030,384,299 - 30,384,610RGDNCBI36
Celera2027,676,669 - 27,676,980RGD
Cytogenetic Map20q11.21UniSTS
HuRef2027,709,065 - 27,709,376UniSTS
TNG Radiation Hybrid Map2014400.0UniSTS
G63577  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372030,867,582 - 30,867,681UniSTSGRCh37
Build 362030,331,243 - 30,331,342RGDNCBI36
Celera2027,623,905 - 27,624,004RGD
Cytogenetic Map20q11.21UniSTS
HuRef2027,655,183 - 27,655,282UniSTS
TNG Radiation Hybrid Map2014375.0UniSTS
RH12366  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372030,921,552 - 30,921,742UniSTSGRCh37
Build 362030,385,213 - 30,385,403RGDNCBI36
Celera2027,677,583 - 27,677,773RGD
Cytogenetic Map20q11.21UniSTS
HuRef2027,709,980 - 27,710,170UniSTS
GeneMap99-GB4 RH Map20172.24UniSTS
NCBI RH Map20279.4UniSTS
A002Q37  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372030,921,220 - 30,921,399UniSTSGRCh37
Build 362030,384,881 - 30,385,060RGDNCBI36
Celera2027,677,251 - 27,677,430RGD
Cytogenetic Map20q11.21UniSTS
HuRef2027,709,647 - 27,709,826UniSTS
GeneMap99-GB4 RH Map20175.68UniSTS
NCBI RH Map20279.4UniSTS
A002U20  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372030,919,825 - 30,919,930UniSTSGRCh37
Build 362030,383,486 - 30,383,591RGDNCBI36
Celera2027,675,856 - 27,675,961RGD
Cytogenetic Map20q11.21UniSTS
HuRef2027,708,252 - 27,708,357UniSTS
GeneMap99-GB4 RH Map20172.15UniSTS
NCBI RH Map20279.4UniSTS
D20S582E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372030,919,891 - 30,919,976UniSTSGRCh37
Build 362030,383,552 - 30,383,637RGDNCBI36
Celera2027,675,922 - 27,676,007RGD
Cytogenetic Map20q11.21UniSTS
HuRef2027,708,318 - 27,708,403UniSTS
GeneMap99-GB4 RH Map20175.68UniSTS
NCBI RH Map20279.4UniSTS
IB1791  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map20q11.21UniSTS
GeneMap99-GB4 RH Map20168.36UniSTS
Whitehead-RH Map20172.5UniSTS
NCBI RH Map20279.4UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2376 1449 1571 465 1155 322 3299 947 3603 416 1453 1606 158 1 1172 1905 4 1
Low 63 1515 155 159 768 143 1058 1250 131 3 7 7 17 32 883 2 1
Below cutoff 27 28

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_004798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047440589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047440590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001754435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB002357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK302403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL121897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL353976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL354800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ431652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU621710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA805755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ579680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000375712   ⟹   ENSP00000364864
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2032,277,651 - 32,335,011 (+)Ensembl
RefSeq Acc Id: NM_004798   ⟹   NP_004789
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382032,277,651 - 32,335,011 (+)NCBI
GRCh372030,865,443 - 30,922,814 (+)NCBI
Build 362030,329,128 - 30,386,475 (+)NCBI Archive
HuRef2027,653,055 - 27,711,242 (+)ENTREZGENE
CHM1_12030,769,227 - 30,827,250 (+)NCBI
T2T-CHM13v2.02034,001,508 - 34,059,883 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047440589   ⟹   XP_047296545
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382032,301,770 - 32,335,011 (+)NCBI
RefSeq Acc Id: XM_047440590   ⟹   XP_047296546
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382032,278,118 - 32,335,011 (+)NCBI
RefSeq Acc Id: XM_054324228   ⟹   XP_054180203
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02034,025,625 - 34,059,883 (+)NCBI
RefSeq Acc Id: XM_054324229   ⟹   XP_054180204
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02034,001,973 - 34,059,883 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_004789   ⟸   NM_004798
- UniProtKB: B4DSR5 (UniProtKB/Swiss-Prot),   B2RMP4 (UniProtKB/Swiss-Prot),   E1P5M5 (UniProtKB/Swiss-Prot),   O15066 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000364864   ⟸   ENST00000375712
RefSeq Acc Id: XP_047296546   ⟸   XM_047440590
- Peptide Label: isoform X1
- UniProtKB: O15066 (UniProtKB/Swiss-Prot),   B4DSR5 (UniProtKB/Swiss-Prot),   B2RMP4 (UniProtKB/Swiss-Prot),   E1P5M5 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_047296545   ⟸   XM_047440589
- Peptide Label: isoform X1
- UniProtKB: O15066 (UniProtKB/Swiss-Prot),   B4DSR5 (UniProtKB/Swiss-Prot),   B2RMP4 (UniProtKB/Swiss-Prot),   E1P5M5 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054180204   ⟸   XM_054324229
- Peptide Label: isoform X1
- UniProtKB: O15066 (UniProtKB/Swiss-Prot),   B4DSR5 (UniProtKB/Swiss-Prot),   B2RMP4 (UniProtKB/Swiss-Prot),   E1P5M5 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054180203   ⟸   XM_054324228
- Peptide Label: isoform X1
- UniProtKB: O15066 (UniProtKB/Swiss-Prot),   B4DSR5 (UniProtKB/Swiss-Prot),   B2RMP4 (UniProtKB/Swiss-Prot),   E1P5M5 (UniProtKB/Swiss-Prot)
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O15066-F1-model_v2 AlphaFold O15066 1-747 view protein structure

Promoters
RGD ID:6798828
Promoter ID:HG_KWN:39023
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000078619
Position:
Human AssemblyChrPosition (strand)Source
Build 362030,328,794 - 30,329,294 (+)MPROMDB
RGD ID:6812045
Promoter ID:HG_ACW:48878
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:KIF3B.BAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 362030,329,716 - 30,330,216 (+)MPROMDB
RGD ID:13206651
Promoter ID:EPDNEW_H26906
Type:initiation region
Name:KIF3B_1
Description:kinesin family member 3B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382032,277,656 - 32,277,716EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6320 AgrOrtholog
COSMIC KIF3B COSMIC
Ensembl Genes ENSG00000101350 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000375712 ENTREZGENE
  ENST00000375712.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.850.10 UniProtKB/Swiss-Prot
GTEx ENSG00000101350 GTEx
HGNC ID HGNC:6320 ENTREZGENE
Human Proteome Map KIF3B Human Proteome Map
InterPro Kinesin-like_fam UniProtKB/Swiss-Prot
  Kinesin_motor_CS UniProtKB/Swiss-Prot
  Kinesin_motor_dom UniProtKB/Swiss-Prot
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report hsa:9371 UniProtKB/Swiss-Prot
NCBI Gene 9371 ENTREZGENE
OMIM 603754 OMIM
PANTHER CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED UniProtKB/Swiss-Prot
  KINESIN-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam Kinesin UniProtKB/Swiss-Prot
PharmGKB PA30103 PharmGKB
PRINTS KINESINHEAVY UniProtKB/Swiss-Prot
PROSITE KINESIN_MOTOR_1 UniProtKB/Swiss-Prot
  KINESIN_MOTOR_2 UniProtKB/Swiss-Prot
SMART KISc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt B2RMP4 ENTREZGENE
  B4DSR5 ENTREZGENE
  E1P5M5 ENTREZGENE
  KIF3B_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B2RMP4 UniProtKB/Swiss-Prot
  B4DSR5 UniProtKB/Swiss-Prot
  E1P5M5 UniProtKB/Swiss-Prot