Mbnl2 (muscleblind-like 2) - Rat Genome Database

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General
Array IDs

Gene: Mbnl2 (muscleblind-like 2) Mus musculus

Symbol:

Mbnl2

Name:

muscleblind-like 2

Description:

ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN regulation of alternative mRNA splicing, via spliceosome; regulation of RNA splicing (ortholog); ASSOCIATED WITH abnormal skeletal muscle fiber morphology; centrally nucleated skeletal muscle fibers; decreased skeletal muscle fiber size; FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

1110002M11Rik; AI047808; AI837313; AI849185; AL118326; KIAA4072; MBLL; mKIAA4072; muscleblind-like protein 2; R75232

Orthologs:

Homo sapiens : MBNL2 (muscleblind-like splicing regulator 2) HGNC
Rattus norvegicus : Mbnl2 (muscleblind-like splicing regulator 2)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	14	120,275,669 - 120,431,698	+	NCBI
Mouse cM Map	14		+	NCBI
Mouse Celera Assembly	14	118,828,759 - 118,986,361	+	NCBI
Mouse Genome Assembly Build 37	14	120,674,891 - 120,830,920	+	NCBI
Mouse Genome Assembly Build 36.1	14	120,674,891 - 120,830,920	+	NCBI
Mouse Cytogenetic Map	14	E4		NCBI

Model

Launch Genome Browser (GBrowse)

Annotation (Toggle Detail/Summary View)

Gene-Chemical Interaction Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
(-)-epigallocatechin 3-gallate	multiple interactions	ISO	RGD:1315628	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MBNL2 mRNA	CTD	PMID:22079256
17alpha-ethynylestradiol	increases expression	ISO	RGD:1591755	6480464	Ethinyl Estradiol results in increased expression of MBNL2 mRNA	CTD	PMID:17108234
17alpha-ethynylestradiol	decreases expression	ISO	RGD:1315628	6480464	Ethinyl Estradiol results in decreased expression of MBNL2 mRNA	CTD	PMID:18936297
17alpha-ethynylestradiol	increases expression	ISO		6480464	Ethinyl Estradiol results in increased expression of MBNL2 mRNA	CTD	PMID:17108234
17alpha-ethynylestradiol	multiple interactions	EXP		6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MBNL2 mRNA	CTD	PMID:17942748
2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	EXP		6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MBNL2 mRNA	CTD	PMID:17942748
2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of MBNL2 mRNA	CTD	PMID:21570461
2-methylcholine	affects expression	ISO	RGD:1315628	6480464	beta-methylcholine affects the expression of MBNL2 mRNA	CTD	PMID:21179406
aflatoxin B1	decreases expression	EXP		6480464	Aflatoxin B1 results in decreased expression of MBNL2 mRNA	CTD	PMID:19770486
all-trans-retinoic acid	increases expression	ISO	RGD:1315628	6480464	Tretinoin results in increased expression of MBNL2 mRNA	CTD	PMID:21934132
all-trans-retinoic acid	increases expression	ISO	RGD:1591755	6480464	Tretinoin results in increased expression of MBNL2 mRNA	CTD	PMID:20488242
benzo[a]pyrene	multiple interactions	EXP		6480464	[Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of MBNL2 mRNA	CTD	PMID:21715664
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of MBNL2 mRNA	CTD	PMID:22228805
benzo[a]pyrene	decreases expression	ISO	RGD:1315628	6480464	Benzo(a)pyrene results in decreased expression of MBNL2 mRNA	CTD	PMID:20064835
bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of MBNL2 mRNA	CTD	PMID:21932408
ciguatoxin CTX1B	affects expression	EXP		6480464	Ciguatoxins affects the expression of MBNL2 mRNA	CTD	PMID:18353800
copper(2+) sulfate	increases expression	ISO	RGD:1315628	6480464	Copper Sulfate results in increased expression of MBNL2 mRNA	CTD	PMID:19549813
cyclosporin A	increases expression	ISO	RGD:1315628	6480464	Cyclosporine results in increased expression of MBNL2 mRNA	CTD	PMID:20106945
cyclosporin A	increases expression	ISO	RGD:1315628	6480464	Cyclosporine results in increased expression of MBNL2 mRNA	CTD	PMID:20106945 PMID:21632981
cyclosporin A	decreases expression	EXP		6480464	Cyclosporine results in decreased expression of MBNL2 mRNA	CTD	PMID:19770486
diarsenic trioxide	increases expression	ISO	RGD:1315628	6480464	arsenic trioxide results in increased expression of MBNL2 mRNA	CTD	PMID:22521957
dibutyl phthalate	increases expression	EXP		6480464	Dibutyl Phthalate results in increased expression of MBNL2 mRNA	CTD	PMID:21266533
dibutyl phthalate	increases expression	ISO	RGD:1591755	6480464	Dibutyl Phthalate results in increased expression of MBNL2 mRNA	CTD	PMID:21266533
dibutyl phthalate	increases expression	ISO		6480464	Dibutyl Phthalate results in increased expression of MBNL2 mRNA	CTD	PMID:21266533
dioxygen	increases expression	ISO	RGD:1315628	6480464	Oxygen deficiency results in increased expression of MBNL2 mRNA	CTD	PMID:20042640
nickel dichloride	increases expression	ISO	RGD:1315628	6480464	nickel chloride results in increased expression of MBNL2 mRNA	CTD	PMID:17312168
paracetamol	affects expression	EXP		6480464	Acetaminophen affects the expression of MBNL2 mRNA	CTD	PMID:17562736
paracetamol	decreases expression	ISO	RGD:1315628	6480464	Acetaminophen results in decreased expression of MBNL2 mRNA	CTD	PMID:21420995
propiconazole	increases expression	EXP		6480464	propiconazole results in increased expression of MBNL2 mRNA	CTD	PMID:21278054
propiconazole	increases expression	EXP		6480464	propiconazole results in increased expression of MBNL2 mRNA	CTD	PMID:21278054 PMID:22334560
quercetin	decreases expression	ISO	RGD:1315628	6480464	Quercetin results in decreased expression of MBNL2 mRNA	CTD	PMID:21632981
raloxifene	multiple interactions	ISO	RGD:1315628	6480464	[Raloxifene co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA	CTD	PMID:19059307
sirolimus	multiple interactions	ISO	RGD:1315628	6480464	Sirolimus inhibits the reaction [TP73 protein results in increased expression of MBNL2 mRNA]	CTD	PMID:21245298
tamoxifen	multiple interactions	ISO	RGD:1315628	6480464	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA	CTD	PMID:19059307
tert-butyl hydroperoxide	decreases expression	ISO	RGD:1315628	6480464	tert-Butylhydroperoxide results in decreased expression of MBNL2 mRNA	CTD	PMID:15336504
testosterone enanthate	affects expression	ISO	RGD:1315628	6480464	testosterone enanthate affects the expression of MBNL2 mRNA	CTD	PMID:17440010
zinc sulfate	decreases expression	ISO	RGD:1315628	6480464	Zinc Sulfate results in decreased expression of MBNL2 mRNA	CTD	PMID:12756304

Gene Ontology Annotations

Biological Process

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
mRNA processing		IEA	UniProtKB-KW:KW-0507	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194
regulation of alternative mRNA splicing, via spliceosome		ISO	UniProtKB:Q9BZC1	2290270	MGI:MGI:2154458	MGI	MGI:MGI:2154458
regulation of alternative mRNA splicing, via spliceosome		IMP		2290270	MGI:MGI:5009479\|PMID:19720736	MGI	MGI:MGI:5009479 PMID:19720736
regulation of RNA splicing		ISO	UniProtKB:Q5VZF2	2290270	MGI:MGI:4834177	MGI	MGI:MGI:4834177
RNA splicing		IEA	UniProtKB-KW:KW-0508	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194

Cellular Component

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
cytoplasm		IEA	UniProtKB-KW:KW-0963	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194
nucleus		IEA	UniProtKB-KW:KW-0539	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194

Molecular Function

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
metal ion binding		IEA	UniProtKB-KW:KW-0479	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194
nucleic acid binding		IEA	InterPro:IPR000571	2290270	MGI:MGI:2152098	UniProtKB	MGI:MGI:2152098
RNA binding		IEA	UniProtKB-KW:KW-0694	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194
zinc ion binding		IEA	InterPro:IPR000571	2290270	MGI:MGI:2152098	UniProtKB	MGI:MGI:2152098

Phenotype Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
abnormal skeletal muscle fiber morphology		IAGP		5509061		MGI	PMID:18213585
centrally nucleated skeletal muscle fibers		IAGP		5509061		MGI	PMID:18213585
decreased skeletal muscle fiber size		IAGP		5509061		MGI	PMID:18213585
impaired muscle relaxation		IAGP		5509061		MGI	PMID:18213585
lordosis		IAGP		5509061		MGI	PMID:18213585
skeletal muscle interstitial fibrosis		IAGP		5509061		MGI	PMID:18213585

Gene-Chemical Interaction Annotations

	(-)-epigallocatechin 3-gallate (ISO)
	17alpha-ethynylestradiol (EXP,ISO)
	2,3,7,8-tetrachlorodibenzodioxine (EXP)
	2-methylcholine (ISO)
	aflatoxin B1 (EXP)
	all-trans-retinoic acid (ISO)
	benzo[a]pyrene (EXP,ISO)
	bisphenol A (EXP)
	ciguatoxin CTX1B (EXP)

	copper(2+) sulfate (ISO)
	cyclosporin A (EXP,ISO)
	diarsenic trioxide (ISO)
	dibutyl phthalate (EXP,ISO)
	dioxygen (ISO)
	nickel dichloride (ISO)
	paracetamol (EXP,ISO)
	propiconazole (EXP)
	quercetin (ISO)

	raloxifene (ISO)
	sirolimus (ISO)
	tamoxifen (ISO)
	tert-butyl hydroperoxide (ISO)
	testosterone enanthate (ISO)
	zinc sulfate (ISO)

Gene Ontology Annotations

Biological Process

	mRNA processing (IEA)
	regulation of alternative mRNA splicing, via spliceosome (IMP,ISO)
	regulation of RNA splicing (ISO)

RNA splicing (IEA)

Cellular Component

cytoplasm (IEA)

nucleus (IEA)

Molecular Function

	metal ion binding (IEA)
	nucleic acid binding (IEA)

	RNA binding (IEA)
	zinc ion binding (IEA)

Phenotype Annotations

	abnormal skeletal muscle fiber morphology (IAGP)
	centrally nucleated skeletal muscle fibers (IAGP)
	decreased skeletal muscle fiber size (IAGP)

	impaired muscle relaxation (IAGP)
	lordosis (IAGP)
	skeletal muscle interstitial fibrosis (IAGP)

References - curated

1.	Kanadia RN, etal., Gene Expr Patterns 2003 Aug;3(4):459-62.
2.	Kawai J, etal., Nature 2001 Feb 8;409(6821):685-90.
3.	MGD and Homologene mouse data transfer
4.	MGD data from the GO Consortium
5.	Okazaki Y, etal., Nature 2002 Dec 5;420(6915):563-73.
6.	RGD automated import pipeline
7.	RGD automated import pipeline for gene-chemical interactions
8.	Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.

References - uncurated

PubMed	10349636
	10512203
	10922068
	11042159
	11076861
	12477932
	12520002
	14610273
	15226823
	15489334
	15618518
	15782199
	15840001
	16141072
	16141073
	16717059
	17967808
	18213585
	18799693
	19075228
	19196664
	19720736
	20009516
	20098426
	20412781
	21194568
	21267068
	22846424
	22884328
	22901804
	23341629
	7671812
	8889548

Genomics

Comparative Map Data

Mbnl2 (Mus musculus)

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	14	120,275,669 - 120,431,698	+	NCBI
Mouse cM Map	14		+	NCBI
Mouse Celera Assembly	14	118,828,759 - 118,986,361	+	NCBI
Mouse Genome Assembly Build 37	14	120,674,891 - 120,830,920	+	NCBI
Mouse Genome Assembly Build 36.1	14	120,674,891 - 120,830,920	+	NCBI
Mouse Cytogenetic Map	14	E4		NCBI

MBNL2 (Homo sapiens)

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	13	78,797,742 - 78,971,749	+	NCBI
Human Genome Assembly HuRef	13	78,471,234 - 78,643,205	+	NCBI
Human Genome Assembly GRCh37	13	97,874,550 - 98,046,374	+	NCBI
Human Celera Assembly	13	78,721,989 - 78,893,793	+	NCBI
Human Genome Assembly Build 36	13	96,672,575 - 96,844,375	+	NCBI
Human Cytogenetic Map	13	q32.1		NCBI

Mbnl2 (Rattus norvegicus)

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	15	q24		NCBI
RGSC Genome Assembly v5.0	15	109,043,305 - 109,200,834	+	NCBI
RGSC Genome Assembly v3.4	15	105,356,456 - 105,514,135	+	NCBI
Rat Celera Assembly	15	96,204,034 - 96,361,422	+	NCBI

Position Markers

RH135852

Map	Chr	Position	Source
Mouse Genome Assembly GRCm38	14	120,429,399 - 120,429,524	UniSTS
Mouse Celera Assembly	14	118,984,061 - 118,984,186	UniSTS
Mouse Genome Assembly Build 37	14	120,828,621 - 120,828,746	UniSTS
Mouse Cytogenetic Map	14	E4	UniSTS

AI837313

Map	Chr	Position	Source
Mouse Genome Assembly GRCm38	14	120,431,419 - 120,431,532	UniSTS
Mouse Whitehead/MRC_RH	14	1253.6	UniSTS
Mouse Celera Assembly	14	118,986,082 - 118,986,195	UniSTS
Mouse Genome Assembly Build 37	14	120,830,641 - 120,830,754	UniSTS
Mouse Cytogenetic Map	14	E4	UniSTS

RH125191

Map	Chr	Position	Source
Mouse Genome Assembly GRCm38	14	120,429,514 - 120,429,598	UniSTS
Mouse Celera Assembly	14	118,984,176 - 118,984,260	UniSTS
Mouse Genome Assembly Build 37	14	120,828,736 - 120,828,820	UniSTS
Mouse Cytogenetic Map	14	E4	UniSTS

UniSTS:237249

Map	Chr	Position	Source
Mouse Genome Assembly GRCm38	14	120,417,090 - 120,417,322	UniSTS
Mouse Celera Assembly	14	118,971,754 - 118,971,986	UniSTS
Mouse Genome Assembly Build 37	14	120,816,312 - 120,816,544	UniSTS
Mouse Cytogenetic Map	14	E4	UniSTS

AI849185

Map	Chr	Position	Source
Mouse Genome Assembly GRCm38	14	120,428,969 - 120,429,097	UniSTS
Mouse Whitehead/MRC_RH	14	1253.6	UniSTS
Mouse Celera Assembly	14	118,983,631 - 118,983,759	UniSTS
Mouse Genome Assembly Build 37	14	120,828,191 - 120,828,319	UniSTS
Mouse Cytogenetic Map	14	E4	UniSTS

D10Mit157.2

Map	Chr	Position	Source
Mouse Whitehead Genetic	10	33.9	UniSTS
Mouse cM Map	10	40.0	UniSTS
Mouse Cytogenetic Map	6	D1	UniSTS
Mouse Cytogenetic Map	16	B4	UniSTS
Mouse Cytogenetic Map	18	E2	UniSTS
Mouse Cytogenetic Map	4	C3	UniSTS
Mouse Cytogenetic Map	7	B2	UniSTS
Mouse Cytogenetic Map	4	D2.3	UniSTS
Mouse Cytogenetic Map	11	E1	UniSTS
Mouse Cytogenetic Map	14	E2.2	UniSTS
Mouse Cytogenetic Map	4	C7	UniSTS
Mouse Cytogenetic Map	2	H4	UniSTS
Mouse Cytogenetic Map	1	F	UniSTS
Mouse Cytogenetic Map	6	C3	UniSTS
Mouse Cytogenetic Map	11	D	UniSTS
Mouse Cytogenetic Map	3	G2	UniSTS
Mouse Cytogenetic Map	17	A1	UniSTS
Mouse Cytogenetic Map	9	F2	UniSTS
Mouse Cytogenetic Map	12	F1	UniSTS
Mouse Cytogenetic Map	19	C2	UniSTS
Mouse Cytogenetic Map	3	B	UniSTS
Mouse Cytogenetic Map	8	C1	UniSTS
Mouse Cytogenetic Map	18	A2	UniSTS
Mouse Cytogenetic Map	3	F2	UniSTS
Mouse Cytogenetic Map	14	C3	UniSTS
Mouse Cytogenetic Map	8	E1	UniSTS
Mouse Cytogenetic Map	8	E2	UniSTS
Mouse Cytogenetic Map	5	B1	UniSTS
Mouse Cytogenetic Map	18	B1	UniSTS
Mouse Cytogenetic Map	9	C	UniSTS
Mouse Cytogenetic Map	14	C2	UniSTS
Mouse Cytogenetic Map	6	A1	UniSTS
Mouse Cytogenetic Map	10	B4	UniSTS
Mouse Cytogenetic Map	13	D2.1	UniSTS
Mouse Cytogenetic Map	5	E5	UniSTS
Mouse Cytogenetic Map	4	D1	UniSTS
Mouse Cytogenetic Map	9	A5.2	UniSTS
Mouse Cytogenetic Map	3	F1	UniSTS
Mouse Cytogenetic Map	11	B3	UniSTS
Mouse Cytogenetic Map	1	H4	UniSTS
Mouse Cytogenetic Map	6	A3	UniSTS
Mouse Cytogenetic Map	15	E1	UniSTS
Mouse Cytogenetic Map	13	D	UniSTS
Mouse Cytogenetic Map	14	B	UniSTS
Mouse Cytogenetic Map	14	D1	UniSTS
Mouse Cytogenetic Map	7	B4	UniSTS
Mouse Cytogenetic Map	X	D	UniSTS
Mouse Cytogenetic Map	17	A3.3	UniSTS
Mouse Cytogenetic Map	7	E2	UniSTS
Mouse Cytogenetic Map	7	A2	UniSTS
Mouse Cytogenetic Map	7	F3	UniSTS
Mouse Cytogenetic Map	9	F1	UniSTS
Mouse Cytogenetic Map	4	E2	UniSTS
Mouse Cytogenetic Map	16	A1	UniSTS
Mouse Cytogenetic Map	8	B3.3	UniSTS
Mouse Cytogenetic Map	3	D	UniSTS
Mouse Cytogenetic Map	15	D2	UniSTS
Mouse Cytogenetic Map	17	B1	UniSTS
Mouse Cytogenetic Map	7	A3	UniSTS
Mouse Cytogenetic Map	15	F1	UniSTS
Mouse Cytogenetic Map	7	C	UniSTS
Mouse Cytogenetic Map	3	F2.1	UniSTS
Mouse Cytogenetic Map	6	F3	UniSTS
Mouse Cytogenetic Map	11	E2	UniSTS
Mouse Cytogenetic Map	11	B5	UniSTS
Mouse Cytogenetic Map	9	F3	UniSTS
Mouse Cytogenetic Map	13	B3	UniSTS
Mouse Cytogenetic Map	9	A4	UniSTS
Mouse Cytogenetic Map	5	A3	UniSTS
Mouse Cytogenetic Map	2	H1	UniSTS
Mouse Cytogenetic Map	16	B1	UniSTS
Mouse Cytogenetic Map	1	A5	UniSTS
Mouse Cytogenetic Map	11	C	UniSTS
Mouse Cytogenetic Map	9	E1	UniSTS
Mouse Cytogenetic Map	6	G1	UniSTS
Mouse Cytogenetic Map	X	A2	UniSTS
Mouse Cytogenetic Map	13	B1	UniSTS
Mouse Cytogenetic Map	5	E2	UniSTS
Mouse Cytogenetic Map	12	C1	UniSTS
Mouse Cytogenetic Map	5	F	UniSTS
Mouse Cytogenetic Map	4	D3	UniSTS
Mouse Cytogenetic Map	10	C2	UniSTS
Mouse Cytogenetic Map	9	B	UniSTS
Mouse Cytogenetic Map	5	G2	UniSTS
Mouse Cytogenetic Map	7	F1	UniSTS
Mouse Cytogenetic Map	12	C3	UniSTS
Mouse Cytogenetic Map	10	A4	UniSTS
Mouse Cytogenetic Map	8	A2	UniSTS
Mouse Cytogenetic Map	18	A1	UniSTS
Mouse Cytogenetic Map	12	A1.1	UniSTS
Mouse Cytogenetic Map	1	C2	UniSTS
Mouse Cytogenetic Map	11	B2	UniSTS
Mouse Cytogenetic Map	6	E3	UniSTS
Mouse Cytogenetic Map	5	C3.3	UniSTS
Mouse Cytogenetic Map	1	B	UniSTS
Mouse Cytogenetic Map	17	A3.1	UniSTS
Mouse Cytogenetic Map	7	A1	UniSTS
Mouse Cytogenetic Map	2	E5	UniSTS
Mouse Cytogenetic Map	11	A1	UniSTS
Mouse Cytogenetic Map	4	B1	UniSTS
Mouse Cytogenetic Map	15	A2	UniSTS
Mouse Cytogenetic Map	8	C3	UniSTS
Mouse Cytogenetic Map	2	A3	UniSTS
Mouse Cytogenetic Map	5	G3	UniSTS
Mouse Cytogenetic Map	4	A3	UniSTS
Mouse Cytogenetic Map	2	H3	UniSTS
Mouse Cytogenetic Map	8	A1	UniSTS
Mouse Cytogenetic Map	8	A1.1	UniSTS
Mouse Cytogenetic Map	16	A3	UniSTS
Mouse Cytogenetic Map	10	B1	UniSTS
Mouse Cytogenetic Map	19	A	UniSTS
Mouse Cytogenetic Map	10	A1	UniSTS
Mouse Cytogenetic Map	13	D1	UniSTS
Mouse Cytogenetic Map	4	A1	UniSTS
Mouse Cytogenetic Map	9	A3	UniSTS
Mouse Cytogenetic Map	17	C	UniSTS
Mouse Cytogenetic Map	1	D	UniSTS
Mouse Cytogenetic Map	5	E3	UniSTS
Mouse Cytogenetic Map	15	D3	UniSTS
Mouse Cytogenetic Map	7	D3	UniSTS
Mouse Cytogenetic Map	2	A1	UniSTS
Mouse Cytogenetic Map	14	C1	UniSTS
Mouse Cytogenetic Map	10	C	UniSTS
Mouse Cytogenetic Map	18	B2	UniSTS
Mouse Cytogenetic Map	2	F1	UniSTS
Mouse Cytogenetic Map	17	A2	UniSTS
Mouse Cytogenetic Map	2	C3	UniSTS
Mouse Cytogenetic Map	1	C3	UniSTS
Mouse Cytogenetic Map	17	B2	UniSTS
Mouse Cytogenetic Map	5	B2	UniSTS
Mouse Cytogenetic Map	5	G1	UniSTS
Mouse Cytogenetic Map	4	C6	UniSTS
Mouse Cytogenetic Map	13	C3	UniSTS
Mouse Cytogenetic Map	2	E1	UniSTS
Mouse Cytogenetic Map	17	A3.2-A3.3	UniSTS
Mouse Cytogenetic Map	19	C3	UniSTS
Mouse Cytogenetic Map	7	E3	UniSTS
Mouse Cytogenetic Map	13	C1	UniSTS
Mouse Cytogenetic Map	9	E3.1	UniSTS
Mouse Cytogenetic Map	15	E3	UniSTS
Mouse Cytogenetic Map	6	B1	UniSTS
Mouse Cytogenetic Map	X	E3	UniSTS
Mouse Cytogenetic Map	4	C4	UniSTS
Mouse Cytogenetic Map	3	E3	UniSTS
Mouse Cytogenetic Map	11	A4	UniSTS
Mouse Cytogenetic Map	4	C5	UniSTS
Mouse Cytogenetic Map	18	B3	UniSTS
Mouse Cytogenetic Map	9	A2	UniSTS
Mouse Cytogenetic Map	7	E1	UniSTS
Mouse Cytogenetic Map	5	D-E1	UniSTS
Mouse Cytogenetic Map	5	B3	UniSTS
Mouse Cytogenetic Map	13	A2-A3	UniSTS
Mouse Cytogenetic Map	5	A2	UniSTS
Mouse Cytogenetic Map	4	B3	UniSTS
Mouse Cytogenetic Map	1	E4	UniSTS
Mouse Cytogenetic Map	17	E4	UniSTS
Mouse Cytogenetic Map	1	G2	UniSTS
Mouse Cytogenetic Map	15	B3.1	UniSTS
Mouse Cytogenetic Map	12	E	UniSTS
Mouse Cytogenetic Map	X	A5	UniSTS
Mouse Cytogenetic Map	6	A3.3	UniSTS
Mouse Cytogenetic Map	6	G3	UniSTS
Mouse Cytogenetic Map	6	F2	UniSTS
Mouse Cytogenetic Map	5	C1	UniSTS
Mouse Cytogenetic Map	4	D2.1	UniSTS
Mouse Cytogenetic Map	4	A5	UniSTS
Mouse Cytogenetic Map	3	F2.2	UniSTS
Mouse Cytogenetic Map	1	E3-E4	UniSTS
Mouse Cytogenetic Map	9	F1-F3	UniSTS
Mouse Cytogenetic Map	1	C1.1	UniSTS
Mouse Cytogenetic Map	14	D2	UniSTS
Mouse Cytogenetic Map	12	A2	UniSTS
Mouse Cytogenetic Map	17	A3-B	UniSTS
Mouse Cytogenetic Map	7	F5	UniSTS
Mouse Cytogenetic Map	14	A3	UniSTS
Mouse Cytogenetic Map	5	G1.1	UniSTS
Mouse Cytogenetic Map	X	F2-F4	UniSTS
Mouse Cytogenetic Map	7	D2	UniSTS
Mouse Cytogenetic Map	2	F3	UniSTS
Mouse Cytogenetic Map	10	A3	UniSTS
Mouse Cytogenetic Map	X	A7.3	UniSTS
Mouse Cytogenetic Map	9	F1-F2	UniSTS
Mouse Cytogenetic Map	13	A3.2	UniSTS
Mouse Cytogenetic Map	10	A2	UniSTS
Mouse Cytogenetic Map	1	C1	UniSTS
Mouse Cytogenetic Map	1	A1	UniSTS
Mouse Cytogenetic Map	12	D3	UniSTS
Mouse Cytogenetic Map	1	A3-A5	UniSTS
Mouse Cytogenetic Map	2	A2	UniSTS
Mouse Cytogenetic Map	3	A1	UniSTS
Mouse Cytogenetic Map	X	A3.3	UniSTS
Mouse Cytogenetic Map	16	A-B1	UniSTS
Mouse Cytogenetic Map	1	D2.3	UniSTS
Mouse Cytogenetic Map	6	B2.3	UniSTS
Mouse Cytogenetic Map	2	G3	UniSTS
Mouse Cytogenetic Map	X	A2-A3.1	UniSTS
Mouse Cytogenetic Map	9	A5.3	UniSTS
Mouse Cytogenetic Map	14	A2-B	UniSTS
Mouse Cytogenetic Map	8	E1-E2	UniSTS
Mouse Cytogenetic Map	8	A3	UniSTS
Mouse Cytogenetic Map	1	G3-H1	UniSTS
Mouse Cytogenetic Map	8	B3-C1	UniSTS
Mouse Cytogenetic Map	19	C1	UniSTS
Mouse Cytogenetic Map	8	C5	UniSTS
Mouse Cytogenetic Map	8	A4	UniSTS
Mouse Cytogenetic Map	15	F3	UniSTS
Mouse Cytogenetic Map	14	E4	UniSTS
Mouse Cytogenetic Map	4	D2.2	UniSTS
Mouse Cytogenetic Map	X	F5	UniSTS
Mouse Cytogenetic Map	11	B1.3	UniSTS
Mouse Cytogenetic Map	17	E3	UniSTS
Mouse Cytogenetic Map	5	E4-E5	UniSTS
Mouse Cytogenetic Map	8	D3	UniSTS
Mouse Cytogenetic Map	1	H2.3	UniSTS
Mouse Cytogenetic Map	10	C1	UniSTS
Mouse Cytogenetic Map	8	D2	UniSTS
Mouse Cytogenetic Map	16	B2	UniSTS
Mouse Cytogenetic Map	1	C4	UniSTS
Mouse Cytogenetic Map	2	B	UniSTS
Mouse Cytogenetic Map	2	H2	UniSTS
Mouse Cytogenetic Map	14	E5	UniSTS
Mouse Cytogenetic Map	10	D3	UniSTS

SGC38389

Map	Chr	Position	Source
Mouse Genome Assembly GRCm38	14	120,431,385 - 120,431,671	UniSTS
Mouse Celera Assembly	14	118,986,048 - 118,986,334	UniSTS
Mouse Genome Assembly Build 37	14	120,830,607 - 120,830,893	UniSTS
Mouse Cytogenetic Map	14	E4	UniSTS

QTLs in Region (Mouse Genome Assembly Build 37)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142274	Plast1_m	plasma plant sterol 1 (mouse)			Not determined		14	21900201	122065662	Mouse
1300909	Ath13_m	atherosclerosis 13 (mouse)			Not determined		14	51915899	165887941	Mouse
4141254	Plast1b_m	plasma plant sterol 1b (mouse)			Not determined		14	54729500	122065662	Mouse
1357869	Fmgty11_m	femur geometry 11 (mouse)			Not determined		14	89665012	123665155	Mouse
4141866	Vmmt10_m	vertebral morphology and mechanical traits 10 (mouse)			Not determined		14	89665012	123665155	Mouse

Sequence

Nucleotide Sequences

Nucleotide RefSeqs	NM_175341	(Get FASTA)	Search GEO for Microarray Profiles
	NM_207515	(Get FASTA)	Search GEO for Microarray Profiles
GenBank Nucleotide	AAHY01118745	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118746	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118747	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118748	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118749	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118750	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118751	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118752	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01118753	(Get FASTA)	Search GEO for Microarray Profiles
	AC154811	(Get FASTA)	Search GEO for Microarray Profiles
	AI461681	(Get FASTA)	Search GEO for Microarray Profiles
	AK003316	(Get FASTA)	Search GEO for Microarray Profiles
	AK028797	(Get FASTA)	Search GEO for Microarray Profiles
	AK040488	(Get FASTA)	Search GEO for Microarray Profiles
	AK085709	(Get FASTA)	Search GEO for Microarray Profiles
	AK148740	(Get FASTA)	Search GEO for Microarray Profiles
	AK151913	(Get FASTA)	Search GEO for Microarray Profiles
	AK151926	(Get FASTA)	Search GEO for Microarray Profiles
	AK151957	(Get FASTA)	Search GEO for Microarray Profiles
	AK153261	(Get FASTA)	Search GEO for Microarray Profiles
	AK159213	(Get FASTA)	Search GEO for Microarray Profiles
	AK164372	(Get FASTA)	Search GEO for Microarray Profiles
	AK167479	(Get FASTA)	Search GEO for Microarray Profiles
	AK167694	(Get FASTA)	Search GEO for Microarray Profiles
	AK178090	(Get FASTA)	Search GEO for Microarray Profiles
	AK178232	(Get FASTA)	Search GEO for Microarray Profiles
	AK192385	(Get FASTA)	Search GEO for Microarray Profiles
	AK206292	(Get FASTA)	Search GEO for Microarray Profiles
	AK216404	(Get FASTA)	Search GEO for Microarray Profiles
	AK217689	(Get FASTA)	Search GEO for Microarray Profiles
	AK220470	(Get FASTA)	Search GEO for Microarray Profiles
	BB673209	(Get FASTA)	Search GEO for Microarray Profiles
	BC020406	(Get FASTA)	Search GEO for Microarray Profiles
	BC023895	(Get FASTA)	Search GEO for Microarray Profiles
	BC026711	(Get FASTA)	Search GEO for Microarray Profiles
	BC075665	(Get FASTA)	Search GEO for Microarray Profiles
	BC079898	(Get FASTA)	Search GEO for Microarray Profiles
	BE336239	(Get FASTA)	Search GEO for Microarray Profiles
	BM932374	(Get FASTA)	Search GEO for Microarray Profiles
	BQ946035	(Get FASTA)	Search GEO for Microarray Profiles
	BY198796	(Get FASTA)	Search GEO for Microarray Profiles
	CAAA01048363	(Get FASTA)	Search GEO for Microarray Profiles
	CF586797	(Get FASTA)	Search GEO for Microarray Profiles
	CH466544	(Get FASTA)	Search GEO for Microarray Profiles
	CT009559	(Get FASTA)	Search GEO for Microarray Profiles
	GQ906534	(Get FASTA)	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

NM_175341

RefSeq Status:

VALIDATED

Type:

CODING

Protein Acc Id:

NP_780550

Peptide Label:

isoform 1

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	14	120,275,669 - 120,431,698	+	ENTREZGENE
Mouse cM Map	14		+	ENTREZGENE
Mouse Celera Assembly	14	118,828,759 - 118,986,361	+	RGD
Mouse Genome Assembly Build 37	14	120,674,891 - 120,830,920	+	RGD

RefSeq Acc Id:

NM_207515

RefSeq Status:

VALIDATED

Type:

CODING

Protein Acc Id:

NP_997398

Peptide Label:

isoform 2

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	14	120,275,669 - 120,431,698	+	ENTREZGENE
Mouse cM Map	14		+	ENTREZGENE
Mouse Celera Assembly	14	118,828,759 - 118,986,361	+	RGD
Mouse Genome Assembly Build 37	14	120,674,891 - 120,830,920	+	RGD

Protein Sequences

Protein RefSeqs	NP_780550	(Get FASTA)
	NP_997398	(Get FASTA)
GenBank Protein	AAH75665	(Get FASTA)
	ACX49758	(Get FASTA)
	BAC26125	(Get FASTA)
	BAC39515	(Get FASTA)
	BAD90497	(Get FASTA)
	BAE30793	(Get FASTA)
	BAE30803	(Get FASTA)
	BAE30829	(Get FASTA)
	BAE34902	(Get FASTA)
	BAE37762	(Get FASTA)
	BAE39560	(Get FASTA)
	EDL00591	(Get FASTA)
	EDL00592	(Get FASTA)
	EDL00593	(Get FASTA)
	EDL00594	(Get FASTA)
	EDL00595	(Get FASTA)
	Q8C181	(Get FASTA)

Promoters

RGD ID:

6825158

Promoter ID:

MM_KWN:17822

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000022738, ENSMUST00000088418, ENSMUST00000088419, NM_175341, NM_207515, UC007UZQ.1, UC007UZT.1

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	14	120,674,566 - 120,675,066	+	MPROMDB

RGD ID:

6888422

Promoter ID:

EPDNEW_M7662

Type:

preliminary

Name:

Mbnl2_1

Description:

muscleblind-like 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	14	120,674,943 - 120,675,003		EPDNEW

RGD ID:

6825159

Promoter ID:

MM_KWN:17823

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day1, 3T3L1_Day4, BoneMarrow_2Hour, BoneMarrow_4Hour, Kidney, Lung, MEF_B6

Transcripts:

UC007UZU.1

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	14	120,695,971 - 120,697,152	+	MPROMDB

RGD ID:

6825156

Promoter ID:

MM_KWN:17824

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, ES_Cell, Lung, MEF_B6

Transcripts:

UC007UZV.1

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	14	120,704,921 - 120,706,172	+	MPROMDB

RGD ID:

6825160

Promoter ID:

MM_KWN:17825

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_4Hour, Brain, Lung, MEF_B6

Transcripts:

UC007UZW.1

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	14	120,723,051 - 120,724,622	+	MPROMDB

RGD ID:

6847116

Promoter ID:

MM_ACW:17145

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_2Hour, BoneMarrow_4Hour, Kidney, Lung

Transcripts:

MBNL2.JSEP07-UNSPLICED

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	14	120,795,526 - 120,796,026	+	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000022139	ENTREZGENE
Ensembl Protein	ENSMUSP00000085763	ENTREZGENE
	ENSMUSP00000126186	ENTREZGENE
Ensembl Transcript	ENSMUST00000088419	ENTREZGENE
	ENSMUST00000167459	ENTREZGENE
Entrez Gene	105559	ENTREZGENE
HomoloGene Group ID	76766	ENTREZGENE
InterPro	Znf_CCCH	UniProtKB/Swiss-Prot
IPI	IPI00224114	UniProtKB/Swiss-Prot
	IPI00225400	UniProtKB/Swiss-Prot
	IPI00555136	UniProtKB/Swiss-Prot
	IPI00828659	UniProtKB/Swiss-Prot
KEGG Report	mmu:105559	ENTREZGENE, UniProtKB/Swiss-Prot
MGD	MGI:2145597	ENTREZGENE
Pfam	zf-CCCH	UniProtKB/Swiss-Prot
PROSITE	ZF_C3H1	UniProtKB/Swiss-Prot
SMART	ZnF_C3H1	UniProtKB/Swiss-Prot
UniProt	D0EX61_MOUSE	UniProtKB/TrEMBL
	MBNL2_MOUSE	UniProtKB/Swiss-Prot

More on Mbnl2
	Entrez Gene
	Ensembl Gene
	Genome Browser
	MGI Report
	NCBI Map Viewer
	Vista
	Vista + UCSC

RGD Object Information
RGD ID:	1315629
Created:	2005-01-12
Species:	Mus musculus
Last Modified:	2013-04-16
Status:	ACTIVE