Map3k5 (mitogen-activated protein kinase kinase kinase 5)

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Keyword

Gene: Map3k5 (mitogen-activated protein kinase kinase kinase 5) Mus musculus

Symbol:

Map3k5

Name:

mitogen-activated protein kinase kinase kinase 5

Description:

ENCODES a protein that exhibits MAP kinase kinase kinase activity; protein kinase binding; ATP binding (ortholog); INVOLVED IN activation of MAPK activity; positive regulation of apoptotic process; regulation of cell death; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH altered response to myocardial infarction; decreased physiological sensitivity to xenobiotic; decreased response of heart to induced stress; FOUND IN cytoplasm (inferred); endoplasmic reticulum (inferred); INTERACTS WITH all-trans-retinoic acid; benzo[a]pyrene; chloroethene

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

7420452D20Rik; apoptosis signal-regulating kinase 1; ASK; ASK-1; ASK1; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; MGC141518; MGC141519; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; OTTMUSP00000040557; OTTMUSP00000040576

Orthologs:

Homo sapiens : MAP3K5 (mitogen-activated protein kinase kinase kinase 5) HGNC
Rattus norvegicus : Map3k5 (mitogen-activated protein kinase kinase kinase 5)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	10	19,934,526 - 20,142,750	+	NCBI
Mouse cM Map	10		+	NCBI
Mouse Celera Assembly	10	19,821,331 - 20,029,886	+	NCBI
Mouse Genome Assembly Build 37	10	19,654,332 - 19,862,556	+	NCBI
Mouse Genome Assembly Build 36.1	10	19,654,278 - 19,861,529	+	NCBI
Mouse Cytogenetic Map	10	A3		NCBI