SERPINB1 (serpin peptidase inhibitor, clade B (ovalbumin), member 1)

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Keyword

Gene: SERPINB1 (serpin peptidase inhibitor, clade B (ovalbumin), member 1) Homo sapiens

Symbol:

SERPINB1

Name:

serpin peptidase inhibitor, clade B (ovalbumin), member 1

Description:

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

anti-elastase; EI; ELANH2; LEI; leukocyte elastase inhibitor; M/NEI; MNEI; monocyte/neutrophil elastase inhibitor; OTTHUMP00000015943; peptidase inhibitor 2; PI-2; PI-2; PI2; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; serpin B1

Orthologs:

Mus musculus : Serpinb1a (serine (or cysteine) peptidase inhibitor, clade B, member 1a) MGI
Rattus norvegicus : Serpinb1a (serine (or cysteine) proteinase inhibitor, clade B, member 1a)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	6	2,764,091 - 2,773,773	-	NCBI
Human Genome Assembly HuRef	6	2,705,973 - 2,715,695	-	NCBI
Human Genome Assembly GRCh37	6	2,832,566 - 2,842,283	-	NCBI
Human Genome Assembly Build 36	6	2,778,732 - 2,787,080	-	NCBI
Human Cytogenetic Map	6	p25		NCBI
Human Genome Assembly	6	2,778,734 - 2,787,080		NCBI