Gene: KCNJ6 (potassium voltage-gated channel subfamily J member 6) Homo sapiens
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Symbol: KCNJ6
Name: potassium voltage-gated channel subfamily J member 6
Description: This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BIR1; G protein-activated inward rectifier potassium channel 2; GIRK-2; GIRK2; hiGIRK2; inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; KATP-2; KATP2; KCNJ7; KIR3.2; KPLBS; MGC126596; OTTHUMP00000109101; potassium channel, inwardly rectifying subfamily J member 6; potassium channel, inwardly rectifying subfamily J, member 6; potassium inwardly-rectifying channel, subfamily J, member 6
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382137,624,223 - 37,916,438 (-)NCBIGRCh38hg38GRCh38
GRCh372138,996,778 - 39,288,741 (-)NCBIGRCh37hg19GRCh37
Build 362137,918,655 - 38,210,566 (-)NCBINCBI36hg18NCBI36
Build 342137,918,656 - 38,210,566NCBI
Celera2124,194,896 - 24,487,265 (-)NCBI
Cytogenetic Map21q22.13NCBImapview
HuRef2124,470,127 - 24,761,921 (-)NCBI
CHM1_12138,557,669 - 38,850,112 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KCNJ6
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
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Vista + UCSC

RGD Object Information
RGD ID: 1313992
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2017-09-12
Status: ACTIVE