Gene: TRPM1 (transient receptor potential cation channel subfamily M member 1) Homo sapiens
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Symbol: TRPM1
Name: transient receptor potential cation channel subfamily M member 1
Description: This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CSNB1C; long transient receptor potential channel 1; LTRPC1; melastatin 1; melastatin-1; MLSN1; OTTHUMP00000159584; transient receptor potential cation channel, subfamily M, member 1; transient receptor potential melastatin family
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381531,001,061 - 31,161,273 (-)NCBIGRCh38hg38GRCh38
GRCh371531,293,264 - 31,453,476 (-)NCBIGRCh37hg19GRCh37
Build 361529,080,829 - 29,181,216 (-)NCBINCBI36hg18NCBI36
Build 341529,080,844 - 29,181,216NCBI
Celera159,019,006 - 9,119,394 (-)NCBI
Cytogenetic Map15q13.3NCBImapview
HuRef158,470,226 - 8,630,487 (-)NCBI
CHM1_11531,284,115 - 31,444,331 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

Nucleotide Sequences
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Additional Information

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Nomenclature History
 
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RGD Object Information
RGD ID: 1312607
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2017-09-05
Status: ACTIVE