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Gene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | | IEA | Ensembl:ENSP00000342105 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | | ISO | RGD:1323814 | 1624291 | PMID:17349958 | RGD | PMID:17349958 | negative regulation of NFAT protein import into nucleus | | IEA | Ensembl:ENSP00000342105 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | negative regulation of NFAT protein import into nucleus | | ISO | RGD:1323814 | 1624291 | PMID:16511445 | RGD | PMID:16511445 | positive regulation of glycogen biosynthetic process | | ISO | RGD:1323814 | 1624291 | PMID:11311121 | RGD | PMID:11311121 | positive regulation of glycogen biosynthetic process | | IEA | Ensembl:ENSP00000342105 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | protein phosphorylation | | ISO | RGD:1323814 | 1624291 | PMID:11311121 | RGD | PMID:11311121 | response to DNA damage stimulus | | ISO | RGD:1323814 | 1624291 | PMID:19965871 | RGD | PMID:19965871 | smoothened signaling pathway | | ISO | RGD:1323814 | 1624291 | PMID:18455992 | RGD | PMID:18455992 | smoothened signaling pathway | | IEA | Ensembl:ENSP00000342105 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Pathway Annotations| External Database Links | |
| Pathway Interaction Database | p53 pathway (PID:200206) |
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| Pathway Interaction Database | p53 pathway (PID:200206) |
References - curated| 1. |
GOA data from the GO Consortium |
| 2. |
Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 3. |
RGD automated data pipeline |
| 4. |
RGD automated import pipeline for gene-chemical interactions |
RGD Disease Portals| Dyrk2 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Dyrk2 (Rattus norvegicus) |
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| DYRK2 (Homo sapiens) |
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| Dyrk2 (Mus musculus) |
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Position Markers| RH140100 |
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| Dyrk2 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001108100 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06049868 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHX01049502 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473960 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_001108100 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001101570 | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001101570 | (Get FASTA) |
| GenBank Protein | EDM16591 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000007821 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000010283 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000010283 | ENTREZGENE, UniProtKB/TrEMBL |
| Entrez Gene | 314862 | ENTREZGENE |
| HomoloGene Group ID | 48437 | ENTREZGENE |
| InterPro | Kinase-like_dom | UniProtKB/TrEMBL |
| Prot_kinase_cat_dom | UniProtKB/TrEMBL | |
| Protein_kinase_ATP_BS | UniProtKB/TrEMBL | |
| Ser/Thr_kinase_AS | UniProtKB/TrEMBL | |
| Ser/Thr_kinase_dom | UniProtKB/TrEMBL | |
| IPI | IPI00360231 | UniProtKB/TrEMBL |
| KEGG Report | rno:314862 | ENTREZGENE |
| Pfam | Pkinase | UniProtKB/TrEMBL |
| PROSITE | PROTEIN_KINASE_ATP | UniProtKB/TrEMBL |
| PROTEIN_KINASE_DOM | UniProtKB/TrEMBL | |
| PROTEIN_KINASE_ST | UniProtKB/TrEMBL | |
| SMART | S_TKc | UniProtKB/TrEMBL |
| Superfamily-SCOP | Kinase_like | UniProtKB/TrEMBL |
| UniGene | Rn.23189 | ENTREZGENE |
| UniProt | F1LYY7_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2008-04-30 | Dyrk2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | Dyrk2_predicted | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (predicted) | 'predicted' is removed | 24709 | APPROVED |
| 2005-01-12 | Dyrk2_predicted | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (predicted) | Symbol and Name status set to approved | 1724 | APPROVED |
| More on Dyrk2 | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 1312039 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




