Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases methylation | ISO | CCDC85A (Homo sapiens) | 6480464 | o and p'-DDT results in increased methylation of CCDC85A gene | CTD | PMID:30822522 | 1,2-dichloroethane | increases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of CCDC85A mRNA | CTD | PMID:28960355 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCDC85A mRNA | CTD | PMID:19933214 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | 2-palmitoylglycerol | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of CCDC85A mRNA | CTD | PMID:37199045 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CCDC85A mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC85A mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CCDC85A mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Ccdc85a (Mus musculus) | 6480464 | bisphenol S results in increased methylation of CCDC85A exon | CTD | PMID:33297965 | aflatoxin B1 | increases methylation | ISO | CCDC85A (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of CCDC85A exon and Aflatoxin B1 results in increased methylation of CCDC85A intron | CTD | PMID:30157460 | arsane | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Arsenic results in decreased expression of CCDC85A mRNA | CTD | PMID:19654921 | arsenic atom | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Arsenic results in decreased expression of CCDC85A mRNA | CTD | PMID:19654921 | benzo[a]pyrene | increases methylation | ISO | CCDC85A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CCDC85A promoter | CTD | PMID:27901495 | benzo[e]pyrene | decreases methylation | ISO | CCDC85A (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of CCDC85A intron | CTD | PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CCDC85A mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | bisphenol A results in increased expression of CCDC85A mRNA | CTD | PMID:32156529 | bisphenol A | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC85A mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CCDC85A mRNA | CTD | PMID:28628672 | cadmium atom | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCDC85A mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCDC85A mRNA | CTD | PMID:35301059 | calcitriol | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of CCDC85A mRNA | CTD | PMID:21592394 | calcitriol | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Calcitriol results in increased expression of CCDC85A mRNA | CTD | PMID:21592394 | carbon nanotube | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CCDC85A gene] | CTD | PMID:28238834 | chloroprene | increases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Chloroprene results in increased expression of CCDC85A mRNA | CTD | PMID:23125180 | choline | multiple interactions | ISO | Ccdc85a (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCDC85A gene | CTD | PMID:20938992 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CCDC85A mRNA | CTD | PMID:26033743 | copper atom | multiple interactions | EXP | | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of CCDC85A mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | EXP | | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of CCDC85A mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CCDC85A mRNA | CTD | PMID:26033743 | crocidolite asbestos | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of CCDC85A mRNA | CTD | PMID:29279043 | DDE | increases methylation | ISO | CCDC85A (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased methylation of CCDC85A gene | CTD | PMID:30822522 | DDT | decreases methylation | EXP | | 6480464 | DDT results in decreased methylation of CCDC85A gene | CTD | PMID:31682807 | dexamethasone | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of CCDC85A mRNA | CTD | PMID:25047013 | dexamethasone | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC85A mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CCDC85A mRNA | CTD | PMID:28628672 | dichloroacetic acid | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Dichloroacetic Acid results in decreased expression of CCDC85A mRNA | CTD | PMID:28962523 | dorsomorphin | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC85A mRNA | CTD | PMID:27188386 | ethanol | affects expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Ethanol affects the expression of CCDC85A mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Ccdc85a (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCDC85A gene | CTD | PMID:20938992 | folic acid | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Folic Acid results in decreased expression of CCDC85A mRNA | CTD | PMID:25629700 | formaldehyde | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of CCDC85A mRNA | CTD | PMID:23649840 | glycidol | increases expression | EXP | | 6480464 | glycidol results in increased expression of CCDC85A mRNA | CTD | PMID:24915197 | Indeno[1,2,3-cd]pyrene | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | indeno(1 more ... | CTD | PMID:26377693 | indometacin | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC85A mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CCDC85A mRNA | CTD | PMID:28628672 | isoprenaline | increases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Isoproterenol results in increased expression of CCDC85A mRNA | CTD | PMID:20003209 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of CCDC85A mRNA | CTD | PMID:20080153 | L-methionine | multiple interactions | ISO | Ccdc85a (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCDC85A gene | CTD | PMID:20938992 | lead(0) | affects expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Lead affects the expression of CCDC85A mRNA | CTD | PMID:28903495 | lipopolysaccharide | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | lipopolysaccharide | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of CCDC85A mRNA | CTD | PMID:35811015 | methapyrilene | decreases methylation | ISO | CCDC85A (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of CCDC85A intron | CTD | PMID:30157460 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of CCDC85A gene | CTD | PMID:35440735 | nickel atom | decreases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Nickel results in decreased expression of CCDC85A mRNA | CTD | PMID:25583101 | ozone | multiple interactions | ISO | Ccdc85a (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CCDC85A mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of CCDC85A mRNA | CTD | PMID:27106289 and PMID:34911549 | phenylmercury acetate | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC85A mRNA | CTD | PMID:27188386 | pioglitazone | multiple interactions | ISO | Ccdc85a (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC85A mRNA | CTD | PMID:27935865 | resveratrol | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of CCDC85A mRNA | CTD | PMID:23557933 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of CCDC85A mRNA | CTD | PMID:28374803 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC85A mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of CCDC85A mRNA | CTD | PMID:25895662 | sodium arsenite | decreases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CCDC85A mRNA | CTD | PMID:34032870 | testosterone | multiple interactions | ISO | CCDC85A (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of CCDC85A mRNA | CTD | PMID:21592394 | testosterone | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Testosterone results in increased expression of CCDC85A mRNA | CTD | PMID:21592394 | titanium dioxide | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of CCDC85A mRNA | CTD | PMID:23557971 | tremolite asbestos | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | tremolite results in decreased expression of CCDC85A mRNA | CTD | PMID:29279043 | trichostatin A | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | trichostatin A results in increased expression of CCDC85A mRNA | CTD | PMID:24935251 | trimellitic anhydride | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of CCDC85A mRNA | CTD | PMID:19042947 | valproic acid | increases expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CCDC85A mRNA | CTD | PMID:24383497 | valproic acid | affects expression | ISO | CCDC85A (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CCDC85A mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | Ccdc85a (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of CCDC85A mRNA | CTD | PMID:24896083 | |