Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TSTD2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TSTD2 mRNA | CTD | PMID:28628672 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TSTD2 mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TSTD2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TSTD2 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | Tstd2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of TSTD2 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | TSTD2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TSTD2 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TSTD2 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TSTD2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TSTD2 mRNA | CTD | PMID:32699268 | antirheumatic drug | increases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of TSTD2 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | affects methylation | ISO | TSTD2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TSTD2 5' UTR | CTD | PMID:27901495 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TSTD2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TSTD2 mRNA | CTD | PMID:34947998 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of TSTD2 promoter | CTD | PMID:22457795 | clotrimazole | decreases expression | EXP | | 6480464 | Clotrimazole results in decreased expression of TSTD2 mRNA | CTD | PMID:30047161 | cyclosporin A | increases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TSTD2 mRNA | CTD | PMID:20106945 and PMID:25562108 | dexamethasone | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TSTD2 mRNA | CTD | PMID:28628672 | doxorubicin | decreases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TSTD2 mRNA | CTD | PMID:29803840 | indometacin | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TSTD2 mRNA | CTD | PMID:28628672 | methidathion | decreases expression | ISO | Tstd2 (Mus musculus) | 6480464 | methidathion results in decreased expression of TSTD2 mRNA | CTD | PMID:34813904 | ozone | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TSTD2 mRNA more ... | CTD | PMID:32699268 | paracetamol | decreases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TSTD2 mRNA | CTD | PMID:21420995 | pentachlorophenol | increases expression | ISO | Tstd2 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of TSTD2 mRNA | CTD | PMID:23892564 | perfluorononanoic acid | increases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of TSTD2 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | increases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of TSTD2 mRNA | CTD | PMID:25812627 | pirinixic acid | multiple interactions | ISO | Tstd2 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TSTD2 mRNA | CTD | PMID:19710929 | resveratrol | multiple interactions | ISO | TSTD2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TSTD2 mRNA | CTD | PMID:23557933 | silver atom | decreases expression | ISO | Tstd2 (Mus musculus) | 6480464 | Silver results in decreased expression of TSTD2 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Tstd2 (Mus musculus) | 6480464 | Silver results in decreased expression of TSTD2 mRNA | CTD | PMID:27131904 | sodium arsenite | decreases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TSTD2 mRNA | CTD | PMID:28595984 more ... | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of TSTD2 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TSTD2 mRNA | CTD | PMID:31533062 | tebuconazole | decreases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | tebuconazole results in decreased expression of TSTD2 mRNA | CTD | PMID:30458266 | tetrachloroethene | decreases expression | ISO | Tstd2 (Mus musculus) | 6480464 | Tetrachloroethylene results in decreased expression of TSTD2 mRNA | CTD | PMID:28973375 | tetrachloromethane | increases expression | ISO | Tstd2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of TSTD2 mRNA | CTD | PMID:31919559 | trovafloxacin | increases expression | ISO | Tstd2 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of TSTD2 mRNA | CTD | PMID:35537566 | valproic acid | affects expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TSTD2 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | TSTD2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TSTD2 mRNA | CTD | PMID:28001369 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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