Man1a1 (mannosidase, alpha, class 1A, member 1) - Rat Genome Database

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Gene: Man1a1 (mannosidase, alpha, class 1A, member 1) Rattus norvegicus
Analyze
Symbol: Man1a1
Name: mannosidase, alpha, class 1A, member 1
RGD ID: 1310891
Description: Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in protein targeting to ER. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and endoplasmic reticulum-Golgi intermediate compartment. Predicted to be active in Golgi membrane and endoplasmic reticulum. Orthologous to human MAN1A1 (mannosidase alpha class 1A member 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Aa2-166; LOC294567; Man1a; Man1a_predicted; mannosidase 1, alpha; mannosidase 1, alpha (predicted); mannosyl-oligosaccharide 1,2-alpha-mannosidase IA; mannosyl-oligosaccharide alpha-1,2-mannosidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82033,745,158 - 33,928,584 (-)NCBIGRCr8
mRatBN7.22033,202,509 - 33,385,747 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2033,202,517 - 33,385,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2034,243,805 - 34,417,921 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02033,634,516 - 33,808,635 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02034,361,433 - 34,535,551 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02035,257,688 - 35,450,132 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2035,257,985 - 35,450,513 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02037,014,560 - 37,204,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42032,582,507 - 32,766,761 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12032,597,679 - 32,672,777 (-)NCBI
Celera2034,596,324 - 34,772,507 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3',5'-cyclic AMP  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bicalutamide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
isoprenaline  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
mercury dibromide  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylisothiazolinone  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11042173   PMID:12477932   PMID:15308636   PMID:17456197   PMID:19056867   PMID:19946888   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Man1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82033,745,158 - 33,928,584 (-)NCBIGRCr8
mRatBN7.22033,202,509 - 33,385,747 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2033,202,517 - 33,385,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2034,243,805 - 34,417,921 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02033,634,516 - 33,808,635 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02034,361,433 - 34,535,551 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02035,257,688 - 35,450,132 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2035,257,985 - 35,450,513 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02037,014,560 - 37,204,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42032,582,507 - 32,766,761 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12032,597,679 - 32,672,777 (-)NCBI
Celera2034,596,324 - 34,772,507 (-)NCBICelera
Cytogenetic Map20q11NCBI
MAN1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386119,177,205 - 119,350,605 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6119,177,205 - 119,349,761 (-)EnsemblGRCh38hg38GRCh38
GRCh376119,498,370 - 119,670,926 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366119,540,965 - 119,712,625 (-)NCBINCBI36Build 36hg18NCBI36
Build 346119,540,965 - 119,712,625NCBI
Celera6120,243,528 - 120,415,211 (-)NCBICelera
Cytogenetic Map6q22.31NCBI
HuRef6117,080,487 - 117,252,887 (-)NCBIHuRef
CHM1_16119,762,560 - 119,935,122 (-)NCBICHM1_1
T2T-CHM13v2.06120,363,405 - 120,543,535 (-)NCBIT2T-CHM13v2.0
Man1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391053,780,881 - 53,952,712 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1053,780,881 - 53,952,705 (-)EnsemblGRCm39 Ensembl
GRCm381053,904,785 - 54,076,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1053,904,785 - 54,076,609 (-)EnsemblGRCm38mm10GRCm38
MGSCv371053,625,839 - 53,795,602 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361053,594,448 - 53,764,211 (-)NCBIMGSCv36mm8
Celera1054,732,740 - 54,902,785 (-)NCBICelera
Cytogenetic Map10B3NCBI
cM Map1027.4NCBI
Man1a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554361,830,211 - 1,935,970 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554361,830,275 - 1,972,861 (-)NCBIChiLan1.0ChiLan1.0
MAN1A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25139,190,400 - 139,363,179 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16137,087,348 - 137,260,129 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06116,984,842 - 117,157,623 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16121,125,027 - 121,297,408 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6121,127,656 - 121,298,196 (-)Ensemblpanpan1.1panPan2
MAN1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1159,106,834 - 59,274,936 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl159,109,366 - 59,275,399 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha159,909,291 - 60,075,933 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0159,293,486 - 59,462,360 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl159,293,490 - 59,463,591 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1159,207,080 - 59,373,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0159,034,562 - 59,201,157 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0159,666,423 - 59,835,236 (-)NCBIUU_Cfam_GSD_1.0
Man1a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946109,874,340 - 110,041,486 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366581,983,787 - 2,150,280 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366581,981,203 - 2,148,349 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAN1A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl142,729,722 - 42,896,283 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1142,729,722 - 42,896,290 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2147,894,684 - 48,057,901 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAN1A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11354,494,856 - 54,668,888 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1354,496,370 - 54,671,539 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604026,838,134 - 27,005,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Man1a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479810,986,519 - 11,117,650 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479810,986,465 - 11,117,182 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Man1a1
1363 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:220
Count of miRNA genes:136
Interacting mature miRNAs:163
Transcripts:ENSRNOT00000057422
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat
70158Bp60Blood pressure QTL 603arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)203161428444396023Rat

Markers in Region
D20Rat76  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22033,278,295 - 33,278,545 (+)MAPPERmRatBN7.2
Rnor_6.02035,335,270 - 35,335,519NCBIRnor6.0
Rnor_5.02037,089,597 - 37,089,846UniSTSRnor5.0
RGSC_v3.42032,659,815 - 32,660,065RGDRGSC3.4
RGSC_v3.42032,659,817 - 32,660,066UniSTSRGSC3.4
RGSC_v3.12032,673,560 - 32,674,141RGD
Celera2034,670,615 - 34,670,864UniSTS
SHRSP x BN Map2022.43UniSTS
SHRSP x BN Map2022.43RGD
Cytogenetic Map20q11UniSTS
BF387907  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22033,242,854 - 33,243,028 (+)MAPPERmRatBN7.2
Rnor_6.02035,298,032 - 35,298,205NCBIRnor6.0
Rnor_5.02037,054,061 - 37,054,234UniSTSRnor5.0
RGSC_v3.42032,624,257 - 32,624,430UniSTSRGSC3.4
Celera2034,635,485 - 34,635,658UniSTS
RH 3.4 Map20371.03UniSTS
Cytogenetic Map20q11UniSTS
UniSTS:498241  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22033,204,746 - 33,205,118 (+)MAPPERmRatBN7.2
Rnor_6.02035,259,926 - 35,260,297NCBIRnor6.0
Rnor_5.02037,016,798 - 37,017,169UniSTSRnor5.0
RGSC_v3.42032,583,482 - 32,583,853UniSTSRGSC3.4
Celera2034,597,299 - 34,597,670UniSTS
Cytogenetic Map20q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 38 57 41 19 41 2 2 21 19 27 11 2
Low 5 6 9 53 16 14 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000057422   ⟹   ENSRNOP00000054231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2033,203,772 - 33,384,874 (-)Ensembl
Rnor_6.0 Ensembl2035,258,951 - 35,449,280 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085465   ⟹   ENSRNOP00000072276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2033,202,517 - 33,277,456 (-)Ensembl
Rnor_6.0 Ensembl2035,260,324 - 35,334,430 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000087342   ⟹   ENSRNOP00000069718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2033,203,772 - 33,384,533 (-)Ensembl
Rnor_6.0 Ensembl2035,257,985 - 35,450,513 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101500   ⟹   ENSRNOP00000076820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2033,203,772 - 33,385,824 (-)Ensembl
RefSeq Acc Id: NM_001033656   ⟹   NP_001028828
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82033,746,420 - 33,927,501 (-)NCBI
mRatBN7.22033,203,772 - 33,384,874 (-)NCBI
Rnor_6.02035,258,951 - 35,449,280 (-)NCBI
Rnor_5.02037,014,560 - 37,204,461 (-)NCBI
RGSC_v3.42032,582,507 - 32,766,761 (-)RGD
Celera2034,596,324 - 34,772,507 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256497   ⟹   XP_006256559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82033,745,158 - 33,928,584 (-)NCBI
mRatBN7.22033,202,509 - 33,385,747 (-)NCBI
Rnor_6.02035,257,688 - 35,450,132 (-)NCBI
Rnor_5.02037,014,560 - 37,204,461 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001028828   ⟸   NM_001033656
- UniProtKB: A0A0G2JW29 (UniProtKB/TrEMBL),   A6K4A2 (UniProtKB/TrEMBL),   G3V9N9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256559   ⟸   XM_006256497
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JW29 (UniProtKB/TrEMBL),   A0A8I5ZJA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054231   ⟸   ENSRNOT00000057422
RefSeq Acc Id: ENSRNOP00000072276   ⟸   ENSRNOT00000085465
RefSeq Acc Id: ENSRNOP00000069718   ⟸   ENSRNOT00000087342
RefSeq Acc Id: ENSRNOP00000076820   ⟸   ENSRNOT00000101500

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JW29-F1-model_v2 AlphaFold A0A0G2JW29 1-746 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701631
Promoter ID:EPDNEW_R12155
Type:initiation region
Name:Man1a1_1
Description:mannosidase, alpha, class 1A, member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02035,449,222 - 35,449,282EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310891 AgrOrtholog
BioCyc Gene G2FUF-3618 BioCyc
BioCyc Pathway PWY-7919 [protein N-glycosylation processing phase (plants and animals)] BioCyc
BioCyc Pathway Image PWY-7919 BioCyc
Ensembl Genes ENSRNOG00000000800 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057422 ENTREZGENE
  ENSRNOT00000057422.3 UniProtKB/TrEMBL
  ENSRNOT00000085465.2 UniProtKB/TrEMBL
  ENSRNOT00000087342.2 UniProtKB/TrEMBL
  ENSRNOT00000101500.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7302739 IMAGE-MGC_LOAD
InterPro 6hp_glycosidase-like_sf UniProtKB/TrEMBL
  Glyco_hydro_47 UniProtKB/TrEMBL
  Seven-hairpin_glycosidases UniProtKB/TrEMBL
KEGG Report rno:294410 UniProtKB/TrEMBL
MGC_CLONE MGC:105974 IMAGE-MGC_LOAD
NCBI Gene Man1a1 ENTREZGENE
PANTHER MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IA UniProtKB/TrEMBL
  MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED UniProtKB/TrEMBL
Pfam Glyco_hydro_47 UniProtKB/TrEMBL
PhenoGen Man1a1 PhenoGen
PRINTS GLYHDRLASE47 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000800 RatGTEx
Superfamily-SCOP Glyco_hydro_47 UniProtKB/TrEMBL
UniProt A0A0G2JW29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZJA7 ENTREZGENE, UniProtKB/TrEMBL
  A6K4A2 ENTREZGENE, UniProtKB/TrEMBL
  G3V9N9 ENTREZGENE, UniProtKB/TrEMBL
  Q5D005_RAT UniProtKB/TrEMBL
  Q7TP80_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-06 Man1a1  mannosidase, alpha, class 1A, member 1  Man1a  mannosidase 1, alpha   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Man1a  mannosidase 1, alpha   Man1a_predicted  mannosidase 1, alpha (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Man1a_predicted  mannosidase 1, alpha (predicted)      Symbol and Name status set to approved 70820 APPROVED