Larp4b (La ribonucleoprotein 4B) - Rat Genome Database

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Gene: Larp4b (La ribonucleoprotein 4B) Rattus norvegicus
Analyze
Symbol: Larp4b
Name: La ribonucleoprotein 4B
RGD ID: 1310713
Description: Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in positive regulation of 3'-UTR-mediated mRNA stabilization and positive regulation of translation. Predicted to be located in nucleolus. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human LARP4B (La ribonucleoprotein 4B); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: La ribonucleoprotein domain family, member 4B; La ribonucleoprotein domain family, member 5; la-related protein 4B; Larp5; LOC307070; RGD1310713; similar to expressed sequence AI256361
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81765,813,125 - 65,908,920 (-)NCBIGRCr8
mRatBN7.21761,138,663 - 61,217,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1764,342,474 - 64,421,256 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01768,345,568 - 68,424,348 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01762,506,614 - 62,585,282 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01763,236,007 - 63,317,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1763,265,407 - 63,314,019 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01765,007,058 - 65,085,258 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41771,931,605 - 72,010,103 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11771,943,684 - 72,020,936 (-)NCBI
Celera1759,363,334 - 59,441,817 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasmic stress granule  (IBA,ISO)
cytosol  (IBA,ISO)
nucleolus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19946888   PMID:20573744   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Larp4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81765,813,125 - 65,908,920 (-)NCBIGRCr8
mRatBN7.21761,138,663 - 61,217,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1764,342,474 - 64,421,256 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01768,345,568 - 68,424,348 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01762,506,614 - 62,585,282 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01763,236,007 - 63,317,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1763,265,407 - 63,314,019 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01765,007,058 - 65,085,258 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41771,931,605 - 72,010,103 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11771,943,684 - 72,020,936 (-)NCBI
Celera1759,363,334 - 59,441,817 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
LARP4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810806,914 - 988,341 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10806,933 - 931,821 (-)EnsemblGRCh38hg38GRCh38
GRCh3710852,854 - 977,645 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610845,484 - 921,702 (-)NCBINCBI36Build 36hg18NCBI36
Celera10805,808 - 882,035 (-)NCBICelera
Cytogenetic Map10p15.3NCBI
HuRef10792,203 - 916,997 (-)NCBIHuRef
CHM1_110852,377 - 977,610 (-)NCBICHM1_1
T2T-CHM13v2.010804,686 - 932,709 (-)NCBIT2T-CHM13v2.0
Larp4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,143,643 - 9,224,487 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,143,917 - 9,224,487 (+)EnsemblGRCm39 Ensembl
GRCm38139,093,653 - 9,174,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl139,093,881 - 9,174,451 (+)EnsemblGRCm38mm10GRCm38
MGSCv37139,093,151 - 9,172,355 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36139,093,151 - 9,172,355 (+)NCBIMGSCv36mm8
Celera139,036,118 - 9,115,259 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map133.66NCBI
Larp4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955492138,374 - 193,145 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955492113,900 - 197,753 (+)NCBIChiLan1.0ChiLan1.0
LARP4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2813,330,417 - 13,452,683 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11013,335,739 - 13,457,978 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010842,621 - 966,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110894,957 - 971,160 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10894,957 - 971,154 (-)Ensemblpanpan1.1panPan2
LARP4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,026,788 - 34,122,144 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl234,026,534 - 34,119,443 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,062,127 - 31,156,072 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0234,411,932 - 34,506,183 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1231,495,099 - 31,589,276 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0232,334,911 - 32,429,094 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0233,081,930 - 33,176,119 (+)NCBIUU_Cfam_GSD_1.0
Larp4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934437,073,263 - 37,137,741 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648413,238,528 - 13,299,448 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648413,238,456 - 13,302,962 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LARP4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11068,621,596 - 68,707,894 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21075,646,959 - 75,711,019 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LARP4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19778,786 - 898,263 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660515,811,979 - 5,950,512 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Larp4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477510,083,476 - 10,145,712 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477510,055,200 - 10,149,178 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Larp4b
272 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:785
Count of miRNA genes:338
Interacting mature miRNAs:463
Transcripts:ENSRNOT00000058548
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)175724672370852846Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat

Markers in Region
D17Rat124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21761,177,516 - 61,177,650 (-)MAPPERmRatBN7.2
Rnor_6.01763,275,714 - 63,275,847NCBIRnor6.0
Rnor_5.01765,046,765 - 65,046,898UniSTSRnor5.0
RGSC_v3.41771,970,266 - 71,970,400RGDRGSC3.4
RGSC_v3.41771,970,267 - 71,970,400UniSTSRGSC3.4
RGSC_v3.11771,981,067 - 71,981,616RGD
Celera1759,402,870 - 59,403,009UniSTS
SHRSP x BN Map1732.6999RGD
SHRSP x BN Map1732.6999UniSTS
Cytogenetic Map17q12.1UniSTS
RH129270  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21761,138,816 - 61,139,019 (-)MAPPERmRatBN7.2
Rnor_6.01763,316,988 - 63,317,190NCBIRnor6.0
Rnor_5.01765,084,948 - 65,085,150UniSTSRnor5.0
RGSC_v3.41771,931,713 - 71,931,915UniSTSRGSC3.4
Celera1759,441,507 - 59,441,709UniSTS
Cytogenetic Map17q12.1UniSTS
AA849380  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21761,182,962 - 61,183,117 (-)MAPPERmRatBN7.2
Rnor_6.01763,270,247 - 63,270,401NCBIRnor6.0
Rnor_5.01765,041,298 - 65,041,452UniSTSRnor5.0
RGSC_v3.41771,975,713 - 71,975,867UniSTSRGSC3.4
Celera1759,397,403 - 59,397,557UniSTS
RH 3.4 Map17586.2UniSTS
Cytogenetic Map17q12.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 57 41 19 41 8 10 74 35 41 11 8
Low 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000058548   ⟹   ENSRNOP00000055347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)Ensembl
Rnor_6.0 Ensembl1763,265,444 - 63,313,864 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077471   ⟹   ENSRNOP00000073054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)Ensembl
Rnor_6.0 Ensembl1763,265,407 - 63,314,019 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095591   ⟹   ENSRNOP00000091873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1761,138,709 - 61,184,498 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000120050   ⟹   ENSRNOP00000089771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)Ensembl
RefSeq Acc Id: NM_001107361   ⟹   NP_001100831
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,022 - 65,908,676 (-)NCBI
mRatBN7.21761,138,663 - 61,217,318 (-)NCBI
Rnor_6.01763,236,007 - 63,317,298 (+)NCBI
Rnor_5.01765,007,058 - 65,085,258 (+)NCBI
RGSC_v3.41771,931,605 - 72,010,103 (-)RGD
Celera1759,363,334 - 59,441,817 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095755   ⟹   XP_038951683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095756   ⟹   XP_038951684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,779 (-)NCBI
mRatBN7.21761,138,709 - 61,217,423 (-)NCBI
RefSeq Acc Id: XM_039095757   ⟹   XP_038951685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095758   ⟹   XP_038951686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095760   ⟹   XP_038951688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095761   ⟹   XP_038951689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095762   ⟹   XP_038951690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095763   ⟹   XP_038951691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095764   ⟹   XP_038951692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_063276484   ⟹   XP_063132554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,885 (-)NCBI
RefSeq Acc Id: XM_063276485   ⟹   XP_063132555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,920 (-)NCBI
RefSeq Acc Id: XM_063276486   ⟹   XP_063132556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XM_063276487   ⟹   XP_063132557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XM_063276488   ⟹   XP_063132558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XM_063276489   ⟹   XP_063132559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,865 (-)NCBI
RefSeq Acc Id: XM_063276490   ⟹   XP_063132560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XR_010058882
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,813,125 - 65,908,555 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001100831   ⟸   NM_001107361
- UniProtKB: A6KN12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073054   ⟸   ENSRNOT00000077471
RefSeq Acc Id: ENSRNOP00000055347   ⟸   ENSRNOT00000058548
RefSeq Acc Id: XP_038951684   ⟸   XM_039095756
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951692   ⟸   XM_039095764
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038951686   ⟸   XM_039095758
- Peptide Label: isoform X3
- UniProtKB: D3ZF45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951691   ⟸   XM_039095763
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038951690   ⟸   XM_039095762
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038951689   ⟸   XM_039095761
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038951688   ⟸   XM_039095760
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038951685   ⟸   XM_039095757
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K4I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951683   ⟸   XM_039095755
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000091873   ⟸   ENSRNOT00000095591
RefSeq Acc Id: ENSRNOP00000089771   ⟸   ENSRNOT00000120050
RefSeq Acc Id: XP_063132555   ⟸   XM_063276485
- Peptide Label: isoform X4
- UniProtKB: A6KN12 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132554   ⟸   XM_063276484
- Peptide Label: isoform X3
- UniProtKB: D3ZF45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132559   ⟸   XM_063276489
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063132560   ⟸   XM_063276490
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063132558   ⟸   XM_063276488
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063132557   ⟸   XM_063276487
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A8U8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132556   ⟸   XM_063276486
- Peptide Label: isoform X6
Protein Domains
HTH La-type RNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZF45-F1-model_v2 AlphaFold D3ZF45 1-737 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310713 AgrOrtholog
BioCyc Gene G2FUF-8902 BioCyc
Ensembl Genes ENSRNOG00000015888 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058548.5 UniProtKB/TrEMBL
  ENSRNOT00000077471.2 UniProtKB/TrEMBL
  ENSRNOT00000095591.1 UniProtKB/TrEMBL
  ENSRNOT00000120050.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro La_dom_prot UniProtKB/TrEMBL
  LARP5_RRM UniProtKB/TrEMBL
  Lupus_La_RNA-bd UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:307070 UniProtKB/TrEMBL
NCBI Gene 307070 ENTREZGENE
PANTHER LA-RELATED PROTEIN 4B UniProtKB/TrEMBL
  PTHR22792 UniProtKB/TrEMBL
Pfam PF05383 UniProtKB/TrEMBL
PhenoGen Larp4b PhenoGen
PROSITE HTH_LA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015888 RatGTEx
SMART SM00715 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A0G2K4I2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8U8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AUI4_RAT UniProtKB/TrEMBL
  A6KN12 ENTREZGENE, UniProtKB/TrEMBL
  D3ZF45 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Larp4b  La ribonucleoprotein 4B  Larp4b  La ribonucleoprotein domain family, member 4B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-17 Larp4b  La ribonucleoprotein domain family, member 4B  Larp5  La ribonucleoprotein domain family, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Larp5  La ribonucleoprotein domain family, member 5   Larp5_predicted  La ribonucleoprotein domain family, member 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Larp5_predicted  La ribonucleoprotein domain family, member 5 (predicted)  RGD1310713_predicted  similar to expressed sequence AI256361 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1310713_predicted  similar to expressed sequence AI256361 (predicted)  LOC307070_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC307070_predicted  similar to expressed sequence AI256361 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL