Abhd3 (abhydrolase domain containing 3, phospholipase)

Gene: Abhd3 (abhydrolase domain containing 3, phospholipase) Rattus norvegicus

Analyze

Symbol:

Abhd3

Name:

abhydrolase domain containing 3, phospholipase

RGD ID:

1310655

Description:

Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process; medium-chain fatty acid catabolic process; and phosphatidylcholine metabolic process. Predicted to be located in membrane. Orthologous to human ABHD3 (abhydrolase domain containing 3, phospholipase); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; aflatoxin B1; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

abhydrolase domain containing 3; abhydrolase domain-containing protein 3; LOC291793; phospholipase ABHD3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ABHD3 (abhydrolase domain containing 3, phospholipase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Abhd3 (abhydrolase domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Abhd3 (abhydrolase domain containing 3, phospholipase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ABHD3 (abhydrolase domain containing 3, phospholipase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ABHD3 (abhydrolase domain containing 3, phospholipase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Abhd3 (abhydrolase domain containing 3, phospholipase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ABHD3 (abhydrolase domain containing 3, phospholipase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ABHD3 (abhydrolase domain containing 3, phospholipase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Abhd3 (abhydrolase domain containing 3, phospholipase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	OR10G3 (olfactory receptor family 10 subfamily G member 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ABHD3 (abhydrolase domain containing 3, phospholipase)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Abhd3 (abhydrolase domain containing 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	abhd3 (abhydrolase domain containing 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	EEB1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	EHT1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Hydr1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MGL2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	abhd-3.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	abhd-3.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	abhd3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	1,996,010 - 2,051,311 (-)	NCBI		GRCr8
mRatBN7.2	18	1,723,203 - 1,778,488 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	1,720,718 - 1,803,428 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	1,952,568 - 2,008,143 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	2,740,264 - 2,795,850 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	1,954,460 - 2,010,020 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	1,892,413 - 1,946,840 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	1,892,413 - 1,946,840 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	1,925,174 - 1,979,805 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	2,027,477 - 2,082,082 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	2,027,474 - 2,106,019 (-)	NCBI
Celera	18	1,603,943 - 1,659,266 (-)	NCBI		Celera
Cytogenetic Map	18	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

Niemann-Pick disease type C1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2-palmitoylglycerol (ISO)

7,12-dimethyltetraphene (ISO)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (EXP,ISO)

antirheumatic drug (ISO)

arsenous acid (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

calcitriol (ISO)

cannabidiol (ISO)

chlordecone (ISO)

ciglitazone (ISO)

cisplatin (ISO)

Clofop (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclophosphamide (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

gentamycin (EXP)

GW 501516 (ISO)

inulin (ISO)

mercury dibromide (ISO)

methyl methanesulfonate (ISO)

ochratoxin A (EXP)

p-chloromercuribenzoic acid (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

Soman (EXP)

sulforaphane (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

medium-chain fatty acid biosynthetic process (IBA)

medium-chain fatty acid catabolic process (IBA)

phosphatidylcholine metabolic process (IBA,ISO)

Cellular Component

membrane (IEA)

Molecular Function

acetylesterase activity (IBA)

acylglycerol lipase activity (IBA)

phospholipase A1 activity (IBA,ISO)

phospholipase A2 activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:21926997

Genomics

Comparative Map Data

Abhd3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	1,996,010 - 2,051,311 (-)	NCBI		GRCr8
mRatBN7.2	18	1,723,203 - 1,778,488 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	1,720,718 - 1,803,428 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	1,952,568 - 2,008,143 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	2,740,264 - 2,795,850 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	1,954,460 - 2,010,020 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	1,892,413 - 1,946,840 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	1,892,413 - 1,946,840 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	1,925,174 - 1,979,805 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	2,027,477 - 2,082,082 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	2,027,474 - 2,106,019 (-)	NCBI
Celera	18	1,603,943 - 1,659,266 (-)	NCBI		Celera
Cytogenetic Map	18	p13	NCBI

ABHD3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	21,650,901 - 21,704,774 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	21,650,901 - 21,704,780 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	19,230,862 - 19,284,735 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	17,484,856 - 17,538,724 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	17,484,855 - 17,538,724	NCBI
Celera	18	16,036,856 - 16,090,764 (-)	NCBI		Celera
Cytogenetic Map	18	q11.2	NCBI
HuRef	18	16,077,990 - 16,131,762 (-)	NCBI		HuRef
CHM1_1	18	19,157,962 - 19,211,880 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	21,835,996 - 21,889,881 (-)	NCBI		T2T-CHM13v2.0

Abhd3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	10,644,411 - 10,706,784 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	10,642,092 - 10,706,771 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	10,644,411 - 10,706,783 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	10,642,092 - 10,706,771 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	10,644,409 - 10,706,694 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	10,644,409 - 10,706,694 (-)	NCBI		MGSCv36	mm8
Celera	18	10,674,408 - 10,736,690 (-)	NCBI		Celera
Cytogenetic Map	18	A1	NCBI
cM Map	18	5.28	NCBI

Abhd3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	10,316,297 - 10,356,052 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	10,316,881 - 10,355,760 (-)	NCBI	ChiLan1.0	ChiLan1.0

ABHD3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	39,049,242 - 39,123,372 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	24,741,836 - 24,815,967 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	14,888,915 - 14,944,295 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	18,526,670 - 18,578,874 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	18,527,364 - 18,578,736 (-)	Ensembl	panpan1.1		panPan2

ABHD3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	66,331,687 - 66,383,443 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	66,332,410 - 66,382,942 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	65,785,702 - 65,837,429 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	66,395,969 - 66,447,789 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	66,397,119 - 66,447,792 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	66,061,627 - 66,113,117 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	66,084,767 - 66,136,553 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	66,385,056 - 66,437,451 (+)	NCBI		UU_Cfam_GSD_1.0

Abhd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	62,408,000 - 62,451,161 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936550	1,359,606 - 1,407,925 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936550	1,359,570 - 1,408,080 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABHD3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	106,851,627 - 106,917,531 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	106,851,625 - 106,917,720 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	99,355,413 - 99,401,087 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABHD3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	58,795,497 - 58,842,714 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	58,795,865 - 58,842,824 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	33,573,847 - 33,619,867 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abhd3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	10,073,444 - 10,113,235 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624770	10,073,462 - 10,126,062 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Abhd3
584 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	348
Count of miRNA genes:	206
Interacting mature miRNAs:	247
Transcripts:	ENSRNOT00000041878
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	25758124	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	25758124	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	30558703	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34291613	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34291613	Rat
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat

Markers in Region

BE102283

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	1,765,985 - 1,766,139 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	1,934,308 - 1,934,461	NCBI	Rnor6.0
Rnor_5.0	18	1,967,157 - 1,967,310	UniSTS	Rnor5.0
RGSC_v3.4	18	2,069,770 - 2,069,923	UniSTS	RGSC3.4
Celera	18	1,647,077 - 1,647,230	UniSTS
RH 3.4 Map	18	10.4	UniSTS
Cytogenetic Map	18	p13	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			8						50	8	16
Low	3	41	31	23	19	23	8	10	24	27	25	11	8
Below cutoff		2	18	18		18		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000041878 ⟹ ENSRNOP00000047416

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	1,723,203 - 1,803,428 (-)	Ensembl
Rnor_6.0 Ensembl	18	1,892,413 - 1,946,840 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000110127 ⟹ ENSRNOP00000081406

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	1,720,718 - 1,778,488 (-)	Ensembl

RefSeq Acc Id:

NM_001106162 ⟹ NP_001099632

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	1,996,010 - 2,051,289 (-)	NCBI
mRatBN7.2	18	1,723,203 - 1,778,488 (-)	NCBI
Rnor_6.0	18	1,892,413 - 1,946,840 (-)	NCBI
Rnor_5.0	18	1,925,174 - 1,979,805 (-)	NCBI
RGSC_v3.4	18	2,027,477 - 2,082,082 (-)	RGD
Celera	18	1,603,943 - 1,659,266 (-)	RGD

Sequence:

show sequence

CGCTCCCGCGAGCTGGCCTCCGCTGCAGCTGCGCCGGGCTCGCGCCATGCAGCGCCTGGCCATG
GATCTGCGGGTGCTGTCCCGGGAGCTGGCGCTCTACGTGGAGCACCAGGTTCGCGTGGGTTTCT
TCGGCTCGGGCGTGGGCTTGTCGCTGATCCTGGGCTTCAGCGTCGCCTATGCCTGCTACTACCT
GAGCAGCATTGCCAAGAAACCCCAGTTAGTGATTGGAGGGGAGAGTTTCAGCCGCTTCCTACAG
GACCACTGTCCGGTGGTGACAGAAACCTATTACCCGACGGTCTGGTGCTGGGAGAGCCGAGGAC
AGACACTGCTGAGACCCTTCATCACTGCCAAGCCCCGGGTGCAGTACAGGAATGAACTCATTAA
AACAGCAGACGGAGGACAGATCTCACTGGACTGGTTTGATAACAATAACAGTGCATGCTATGTG
GATGCCAGTACCAGACCTACTATCTTGCTCCTGCCTGGCCTCACTGGAACAAGCAAGGAATCCT
ATATCCTTCATATGATCCATCTCAGTGAAGAATTAGGATACAGGTGTGTGGTTTTTAATAACAG
AGGAGTAGCAGGAGAGAGTCTCTTGACACCTCGGACTTACTGCTGCGCAAACACTGAAGACTTG
GAGGCGGTTATCCACCACGTTCACAGCCTGTACCCTTTGGCCCCCTTTCTGGCAGCAGGCGTGT
CAATGGGAGGAATGCTGCTTCTGAATTACTTGGGTAAAATTGGGTCCAAAACCCCTCTGATGGC
GGCTGCAACGTTTTCGGTTGGCTGGAACACTTTTGCTTGCTCAGAGTCACTGGAGAGACCACTG
AACTGGCTGCTTTTTAATTACTACTTGACAACTTGCCTCCAGTCTTCAGTTAAGAAGCACCGGC
ATATGTTTGTGGGACAGATTGACATGGACCAGGTCATGAAGGCCAAGTCGATCAGAGAGTTTGA
TAGGCGGTTCACCTCCGTCATGTTTGGATACCGTACGCTTGATGACTATTACACAGATGCCAGT
CCAAACCGCAGGCTGAAGTCGGTGGGAATTCCAGTGCTGTGCCTGAATGCTGCAGACGATGTTT
TCTCACCCAGCCACGCTATCCCAATAGAAACTGCTAAGCAAAACCCTAACGTGGCTTTGGTCCT
TACATCGTATGGAGGCCATATTGGTTTTCTGGAGGGAATCTGGCCTAGGCAATGCACTTACATG
GATCGAGTCTTCAAGCAGTTTGTGCAGGCCATGGTTGAGCATGGACATGAACTCTCCAACATGT
AGCTTCTTGGCTGCATTAAGCCTGAACAACTGTTGTTACTGCAGTTGAGCTCAGTGCATGAATT
TTAACTACTGAAGGTAAAGCTGATCCAACAGCAGATGGGTGAAGAGGTCGGCATGACATGCAAA
AACTACTTCTTAGGGAAATAAAACAATTTTGTAGTAAGAAACTAAAAATAGTTTAGATTGTTAC
TGTAGTAGATCTTATTTTTCCTATGCCTTACCGAATATGACCTTAAAATTAAGTAGTCCTTATG
GAAGAGTTGCACTTAACCAAAACTATTGTGTAAAGAGATTTTAATTCCTCAGGGTTTTTATTTA
GGCTAATATTTTTAGATTACTCAGTTTAGGTGACTTAATAGTACTTTAATAACTGTTAAGAGAT
TTTAATGATTTGAATGTAAGTTACAAGAGGGGCATTCATAGTAACAGGATAAAGGATAAATTGC
AATGTGTAAGTGTTTCTTCTGACATTAAAAGGCAAATGCAACAATGTTAGACTGACTTCTATAT
TTGCTCTCTTCTCTGATGATATTAAATTAGGGCTGATTTATGTTTTATAATTATTATTTACATG
CTTATTTTTAAAATAGTATTTGTGAATACATATATTAAAATAAATTCTATCATTTT

hide sequence

RefSeq Acc Id:

XM_063277269 ⟹ XP_063133339

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	2,002,741 - 2,051,307 (-)	NCBI

RefSeq Acc Id:

XM_063277270 ⟹ XP_063133340

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	2,002,741 - 2,051,311 (-)	NCBI

RefSeq Acc Id:

XM_063277271 ⟹ XP_063133341

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	2,002,284 - 2,051,310 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099632	(Get FASTA)	NCBI Sequence Viewer
	XP_063133339	(Get FASTA)	NCBI Sequence Viewer
	XP_063133340	(Get FASTA)	NCBI Sequence Viewer
	XP_063133341	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL86673	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000047416.5
	ENSRNOP00000081406
	ENSRNOP00000081406.1

RefSeq Acc Id:

NP_001099632 ⟸ NM_001106162

- UniProtKB:

A6KNE8 (UniProtKB/TrEMBL), A0A8I5ZSG0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQRLAMDLRVLSRELALYVEHQVRVGFFGSGVGLSLILGFSVAYACYYLSSIAKKPQLVIGGES
FSRFLQDHCPVVTETYYPTVWCWESRGQTLLRPFITAKPRVQYRNELIKTADGGQISLDWFDNN
NSACYVDASTRPTILLLPGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGESLLTPRTYCC
ANTEDLEAVIHHVHSLYPLAPFLAAGVSMGGMLLLNYLGKIGSKTPLMAAATFSVGWNTFACSE
SLERPLNWLLFNYYLTTCLQSSVKKHRHMFVGQIDMDQVMKAKSIREFDRRFTSVMFGYRTLDD
YYTDASPNRRLKSVGIPVLCLNAADDVFSPSHAIPIETAKQNPNVALVLTSYGGHIGFLEGIWP
RQCTYMDRVFKQFVQAMVEHGHELSNM

hide sequence

RefSeq Acc Id:

ENSRNOP00000047416 ⟸ ENSRNOT00000041878

RefSeq Acc Id:

ENSRNOP00000081406 ⟸ ENSRNOT00000110127

RefSeq Acc Id:	XP_063133341 ⟸ XM_063277271
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063133340 ⟸ XM_063277270
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063133339 ⟸ XM_063277269
- Peptide Label:	isoform X1

Protein Domains

AB hydrolase-1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A3D4-F1-model_v2	AlphaFold	D4A3D4	1-411	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700631

Promoter ID:

EPDNEW_R11155

Type:

initiation region

Name:

Abhd3_1

Description:

abhydrolase domain containing 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	1,946,839 - 1,946,899	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310655	AgrOrtholog
BioCyc Gene	G2FUF-8409	BioCyc
Ensembl Genes	ENSRNOG00000029370	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000041878.5	UniProtKB/TrEMBL
	ENSRNOT00000110127	ENTREZGENE
	ENSRNOT00000110127.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB-Hydro_YheT	UniProtKB/TrEMBL
	AB_hydrolase	UniProtKB/TrEMBL
	AB_hydrolase_1	UniProtKB/TrEMBL
	UPF0017_hydro-like_CS	UniProtKB/TrEMBL
KEGG Report	rno:291793	UniProtKB/TrEMBL
NCBI Gene	291793	ENTREZGENE
PANTHER	ABHYDROLASE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	PHOSPHOLIPASE ABHD3	UniProtKB/TrEMBL
Pfam	Abhydrolase_1	UniProtKB/TrEMBL
PhenoGen	Abhd3	PhenoGen
PIRSF	Ab_hydro_YheT	UniProtKB/TrEMBL
PROSITE	UPF0017	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000029370	RatGTEx
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	A0A8I5ZSG0	ENTREZGENE, UniProtKB/TrEMBL
	A6KNE8	ENTREZGENE, UniProtKB/TrEMBL
	D4A3D4_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-02-13	Abhd3	abhydrolase domain containing 3, phospholipase	Abhd3	abhydrolase domain containing 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Abhd3	abhydrolase domain containing 3	Abhd3_predicted	abhydrolase domain containing 3 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Abhd3_predicted	abhydrolase domain containing 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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